GEnome-wide tool for Multi-scale Modeling
data Extraction and Representation
for Saccharomyces cerevisiae

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.

Standard name	Systematic name	Name description	Type	#Experiments	#Methods	#Publications	Evidence
SPC97	YHR172W	Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex	physical	12	5	9	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, FRET, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
CDC5	YMR001C	Polo-like kinase required for mitotic exit	physical	9	7	7	Affinity Capture-MS, Biochemical Activity, Biochemical Activity, Affinity Capture-Western, Protein-peptide, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Two-hybrid
TUB4	YLR212C	Gamma-tubulin	physical	9	5	5	Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Co-localization, Reconstituted Complex, Co-fractionation
STU2	YLR045C	Microtubule polymerase of the XMAP215/Dis1 family	physical	6	3	3	Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Reconstituted Complex
SPC98	YNL126W	Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex	physical	5	4	3	Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-MS
SPC72	YAL047C	Gamma-tubulin small complex (gamma-TuSC) receptor	physical	5	4	3	Two-hybrid, FRET, Reconstituted Complex, PCA, Two-hybrid
NUD1	YOR373W	Mitotic exit network (MEN) scaffold protein	physical	4	3	3	Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Reconstituted Complex
MLP2	YIL149C	Myosin-like protein associated with the nuclear envelope	physical	3	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
BFA1	YJR053W	Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p	physical	3	3	2	Co-localization, FRET, Reconstituted Complex
CRM1	YGR218W	Nuclear export factor, exportin	physical	3	2	2	Two-hybrid, Two-hybrid, Reconstituted Complex
KEL1	YHR158C	Protein required for proper cell fusion and cell morphology	physical	3	1	2	Two-hybrid, Two-hybrid, Two-hybrid
KAR1	YNL188W	Protein involved in karyogamy and spindle pole body duplication	physical	3	3	1	Two-hybrid, Reconstituted Complex, Co-localization
SGM1	YJR134C	Protein of unknown function	physical	3	2	1	PCA, Two-hybrid, Two-hybrid
COY1	YKL179C	Golgi membrane protein with similarity to mammalian CASP	physical	3	2	1	PCA, Two-hybrid, Two-hybrid
BUB2	YMR055C	Mitotic exit network regulator	genetic	2	2	2	Synthetic Lethality, Phenotypic Enhancement
SPC98	YNL126W	Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex	genetic	2	2	2	Dosage Rescue, Synthetic Growth Defect
TUB4	YLR212C	Gamma-tubulin	genetic	2	2	2	Dosage Rescue, Synthetic Growth Defect
CIN8	YEL061C	Bipolar kinesin motor protein	physical	2	1	2	Two-hybrid, Two-hybrid
VAM7	YGL212W	Vacuolar SNARE protein	physical	2	1	2	Two-hybrid, Two-hybrid
YJL113W	YJL113W	Retrotransposon TYA Gag and TYB Pol genes	physical	2	1	2	Two-hybrid, Two-hybrid
IMH1	YLR309C	Protein involved in vesicular transport	physical	2	2	1	PCA, Two-hybrid
END3	YNL084C	EH domain-containing protein involved in endocytosis	physical	2	2	1	PCA, Two-hybrid
VPS20	YMR077C	Myristoylated subunit of the ESCRT-III complex	physical	2	2	1	PCA, Two-hybrid
HDA2	YDR295C	Subunit of HDA1 histone deacetylase complex	physical	2	1	1	Two-hybrid, Two-hybrid
ETP1	YHL010C	Protein of unknown function required for growth on ethanol	physical	2	1	1	Two-hybrid, Two-hybrid
NUF2	YOL069W	Component of the kinetochore-associated Ndc80 complex	physical	2	1	1	Two-hybrid, Two-hybrid
YAP6	YDR259C	Basic leucine zipper (bZIP) transcription factor	physical	2	1	1	Two-hybrid, Two-hybrid
RTG3	YBL103C	bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways	physical	2	1	1	Two-hybrid, Two-hybrid
SNX4	YJL036W	Sorting nexin	physical	2	1	1	Two-hybrid, Two-hybrid
NIP100	YPL174C	Large subunit of the dynactin complex	physical	2	1	1	Two-hybrid, Two-hybrid
FKH1	YIL131C	Forkhead family transcription factor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MED2	YDL005C	Subunit of the RNA polymerase II mediator complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YAP6	YDR259C	Basic leucine zipper (bZIP) transcription factor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
TFC7	YOR110W	RNA pol III transcription initiation factor complex (TFIIIC) subunit	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MED4	YOR174W	Subunit of the RNA polymerase II mediator complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
EAF1	YDR359C	Component of the NuA4 histone acetyltransferase complex	physical	1	1	1	Two-hybrid
NTR2	YKR022C	Essential protein that forms a dimer with Ntr1p	physical	1	1	1	Two-hybrid
FRT2	YAL028W	Tail-anchored ER membrane protein of unknown function	physical	1	1	1	Two-hybrid
SNP1	YIL061C	Component of U1 snRNP required for mRNA splicing via spliceosome	physical	1	1	1	Two-hybrid
RPN1	YHR027C	Non-ATPase base subunit of the 19S RP of the 26S proteasome	physical	1	1	1	Two-hybrid
ACT1	YFL039C	Actin, structural protein in cytoskeleton	genetic	1	1	1	Synthetic Haploinsufficiency
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	physical	1	1	1	Affinity Capture-RNA
ATG14	YBR128C	Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I	physical	1	1	1	Two-hybrid
CDC14	YFR028C	Protein phosphatase required for mitotic exit	physical	1	1	1	Co-localization
CDC3	YLR314C	Component of the septin ring that is required for cytokinesis	physical	1	1	1	Two-hybrid
EDE1	YBL047C	Scaffold protein involved in the formation of early endocytic sites	physical	1	1	1	Two-hybrid
DYN1	YKR054C	Cytoplasmic heavy chain dynein	genetic	1	1	1	Synthetic Growth Defect
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	physical	1	1	1	Affinity Capture-RNA
CCM1	YGR150C	Mitochondrial 15S rRNA-binding protein	physical	1	1	1	Two-hybrid
NOT3	YIL038C	Component of the CCR4-NOT core complex, involved in mRNA decapping	physical	1	1	1	Two-hybrid
PGD1	YGL025C	Subunit of the RNA polymerase II mediator complex	physical	1	1	1	Two-hybrid
CSN9	YDR179C	Subunit of the Cop9 signalosome	physical	1	1	1	Affinity Capture-MS
NUM1	YDR150W	Protein required for nuclear migration	genetic	1	1	1	Synthetic Growth Defect
SET2	YJL168C	Histone methyltransferase with a role in transcriptional elongation	physical	1	1	1	Two-hybrid
CRN1	YLR429W	Coronin	physical	1	1	1	Two-hybrid
SNF7	YLR025W	One of four subunits of the ESCRT-III complex	physical	1	1	1	Two-hybrid
CAF20	YOR276W	Phosphoprotein of the mRNA cap-binding complex	physical	1	1	1	Affinity Capture-RNA
BFA1	YJR053W	Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p	genetic	1	1	1	Synthetic Lethality
ATG11	YPR049C	Adapter protein for pexophagy and the Cvt targeting pathway	physical	1	1	1	Two-hybrid
OM45	YIL136W	Mitochondrial outer membrane protein of unknown function	physical	1	1	1	Two-hybrid
RNA1	YMR235C	GTPase activating protein (GAP) for Gsp1p	physical	1	1	1	Two-hybrid
ARE1	YCR048W	Acyl-CoA:sterol acyltransferase	physical	1	1	1	Two-hybrid
KEL2	YGR238C	Protein that negatively regulates mitotic exit	physical	1	1	1	Two-hybrid
CAF4	YKR036C	WD40 repeat-containing protein associated with the CCR4-NOT complex	physical	1	1	1	Two-hybrid
LHS1	YKL073W	Molecular chaperone of the endoplasmic reticulum lumen	physical	1	1	1	Two-hybrid
CIK1	YMR198W	Kinesin-associated protein	physical	1	1	1	Two-hybrid
NOP53	YPL146C	Nucleolar protein	physical	1	1	1	Two-hybrid
NDE1	YMR145C	Mitochondrial external NADH dehydrogenase	physical	1	1	1	Two-hybrid
CLN2	YPL256C	G1 cyclin involved in regulation of the cell cycle	physical	1	1	1	Reconstituted Complex
SKA1	YKL023W	SKI complex-associated protein	physical	1	1	1	Two-hybrid
ATG1	YGL180W	Protein serine/threonine kinase	physical	1	1	1	Two-hybrid
PKC1	YBL105C	Protein serine/threonine kinase	physical	1	1	1	Two-hybrid
ACA1	YER045C	ATF/CREB family basic leucine zipper (bZIP) transcription factor	physical	1	1	1	Two-hybrid
RGA1	YOR127W	GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP)	physical	1	1	1	Two-hybrid
SPC97	YHR172W	Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex	genetic	1	1	1	Dosage Rescue
YJL114W	YJL114W	Retrotransposon TYA Gag gene co-transcribed with TYB Pol	physical	1	1	1	Two-hybrid
YLR179C	YLR179C	Protein of unknown function with similarity to Tfs1p	physical	1	1	1	Affinity Capture-MS
SSB2	YNL209W	Cytoplasmic ATPase that is a ribosome-associated molecular chaperone	physical	1	1	1	Affinity Capture-MS
SQS1	YNL224C	Protein that stimulates the ATPase and helicase activities of Prp43p	physical	1	1	1	Affinity Capture-MS
TUB1	YML085C	Alpha-tubulin	physical	1	1	1	Co-localization
SWE1	YJL187C	Protein kinase that regulates the G2/M transition	physical	1	1	1	Two-hybrid
YLR031W	YLR031W	Putative protein of unknown function	physical	1	1	1	Two-hybrid
YAP1	YML007W	Basic leucine zipper (bZIP) transcription factor	physical	1	1	1	Two-hybrid
VPS5	YOR069W	Nexin-1 homolog	physical	1	1	1	Two-hybrid
SSO1	YPL232W	Plasma membrane t-SNARE	physical	1	1	1	Two-hybrid
SPR3	YGR059W	Sporulation-specific homolog of the CDC3/10/11/12 family of genes	physical	1	1	1	Two-hybrid
SSA4	YER103W	Heat shock protein that is highly induced upon stress	physical	1	1	1	Two-hybrid
VPS53	YJL029C	Component of the GARP (Golgi-associated retrograde protein) complex	physical	1	1	1	Two-hybrid
TUP1	YCR084C	General repressor of transcription in complex with Cyc8p	physical	1	1	1	Two-hybrid
TSC11	YER093C	Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p)	physical	1	1	1	Two-hybrid
YAP1802	YGR241C	Protein of the AP180 family, involved in clathrin cage assembly	physical	1	1	1	Two-hybrid
ZIP1	YDR285W	Transverse filament protein of the synaptonemal complex	physical	1	1	1	Two-hybrid
YHL009W-A	YHL009W-A	Retrotransposon TYA Gag gene co-transcribed with TYB Pol	physical	1	1	1	Two-hybrid
VPS51	YKR020W	Component of the GARP (Golgi-associated retrograde protein) complex	physical	1	1	1	Two-hybrid
SPO14	YKR031C	Phospholipase D	physical	1	1	1	Two-hybrid
SVL3	YPL032C	Protein of unknown function	physical	1	1	1	Two-hybrid
CLB5	YPR120C	B-type cyclin involved in DNA replication during S phase	physical	1	1	1	Reconstituted Complex
KAR3	YPR141C	Minus-end-directed microtubule motor	physical	1	1	1	Two-hybrid
KAR3	YPR141C	Minus-end-directed microtubule motor	genetic	1	1	1	Synthetic Growth Defect
KAR9	YPL269W	Spindle positioning factor	physical	1	1	1	Co-localization
KAR9	YPL269W	Spindle positioning factor	genetic	1	1	1	Synthetic Growth Defect
MPS1	YDL028C	Dual-specificity kinase	physical	1	1	1	Biochemical Activity
SEC9	YGR009C	t-SNARE protein required for secretory vesicle-plasma membrane fusion	physical	1	1	1	Two-hybrid
SKN7	YHR206W	Nuclear response regulator and transcription factor	physical	1	1	1	Two-hybrid
MPS2	YGL075C	Essential membrane protein localized at nuclear envelope and SPBs	physical	1	1	1	Two-hybrid
CNM67	YNL225C	Component of the spindle pole body outer plaque	genetic	1	1	1	Synthetic Growth Defect
SCC2	YDR180W	Subunit of cohesin loading factor (Scc2p-Scc4p)	physical	1	1	1	Two-hybrid
SPC110	YDR356W	Inner plaque spindle pole body (SPB) component	physical	1	1	1	Co-purification
FCP1	YMR277W	Carboxy-terminal domain (CTD) phosphatase	physical	1	1	1	Two-hybrid
ATC1	YDR184C	Nuclear protein	physical	1	1	1	Two-hybrid
REC107	YJR021C	Protein involved in early stages of meiotic recombination	physical	1	1	1	Two-hybrid
IVY1	YDR229W	Phospholipid-binding protein that interacts with both Ypt7p and Vps33p	physical	1	1	1	Two-hybrid
SCD5	YOR329C	Protein required for normal actin organization and endocytosis	physical	1	1	1	Two-hybrid
SPC25	YER018C	Component of the kinetochore-associated Ndc80 complex	physical	1	1	1	Two-hybrid
SPC42	YKL042W	Central plaque component of spindle pole body (SPB)	physical	1	1	1	Affinity Capture-MS
ENT2	YLR206W	Epsin-like protein required for endocytosis and actin patch assembly	physical	1	1	1	Two-hybrid
LRS4	YDR439W	Nucleolar protein that forms a complex with Csm1p	physical	1	1	1	Two-hybrid
SHE9	YDR393W	Protein required for normal mitochondrial morphology	physical	1	1	1	Two-hybrid
DID2	YKR035W-A	Class E protein of the vacuolar protein-sorting (Vps) pathway	physical	1	1	1	Two-hybrid
EAF7	YNL136W	Subunit of the NuA4 histone acetyltransferase complex	physical	1	1	1	Affinity Capture-Western
KIP1	YBL063W	Kinesin-related motor protein	physical	1	1	1	Two-hybrid
SLK19	YOR195W	Kinetochore-associated protein	physical	1	1	1	Two-hybrid
EPO1	YMR124W	Protein involved in septin-ER tethering	physical	1	1	1	Two-hybrid
FMP27	YLR454W	Protein with structural similarity to lipid transport protein Vps13p	physical	1	1	1	Two-hybrid
KIP2	YPL155C	Kinesin-related motor protein involved in mitotic spindle positioning	physical	1	1	1	Two-hybrid
KIP2	YPL155C	Kinesin-related motor protein involved in mitotic spindle positioning	genetic	1	1	1	Synthetic Growth Defect
NDJ1	YOL104C	Protein that regulates meiotic SPB cohesion and telomere clustering	physical	1	1	1	Affinity Capture-MS
ASE1	YOR058C	Mitotic spindle midzone-localized microtubule bundling protein	physical	1	1	1	Two-hybrid
KIN4	YOR233W	Serine/threonine protein kinase	physical	1	1	1	Affinity Capture-Western
MRS2	YOR334W	Mitochondrial inner membrane Mg(2+) channel	physical	1	1	1	Two-hybrid
APJ1	YNL077W	Hsp40 chaperone with a role in SUMO-mediated protein degradation	physical	1	1	1	Affinity Capture-MS
SKS1	YPL026C	Putative serine/threonine protein kinase	physical	1	1	1	Two-hybrid
PUF2	YPR042C	PUF family mRNA-binding protein	physical	1	1	1	Affinity Capture-RNA
SMY1	YKL079W	Kinesin-like myosin passenger-protein	physical	1	1	1	Two-hybrid
SGO1	YOR073W	Component of the spindle checkpoint	physical	1	1	1	Two-hybrid
MPS3	YJL019W	Nuclear envelope protein	physical	1	1	1	Two-hybrid
KIP3	YGL216W	Kinesin-related antiparallel sliding motor protein	genetic	1	1	1	Synthetic Growth Defect
LGE1	YPL055C	Protein involved in histone H2B ubiquitination	physical	1	1	1	Two-hybrid
RRP17	YDR412W	5' exoribonuclease required for 5' end processing of pre-60S rRNA	physical	1	1	1	Two-hybrid
LAM4	YHR080C	Sterol-binding protein that localizes to puncta in the cortical ER	physical	1	1	1	Two-hybrid
CMI7	YIL002W-A	Putative mitochondrial protein of unknown function	physical	1	1	1	Two-hybrid
ARR1	YPR199C	Transcriptional activator of the basic leucine zipper (bZIP) family	physical	1	1	1	Two-hybrid
CHM7	YJL049W	Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum	physical	1	1	1	Two-hybrid
LNP1	YHR192W	Lunapark family member involved in ER network formation	physical	1	1	1	Two-hybrid
NCA2	YPR155C	Protein that regulates expression of Fo-F1 ATP synthase subunits	physical	1	1	1	Two-hybrid
RCF1	YML030W	Cytochrome c oxidase subunit	physical	1	1	1	Two-hybrid
RCI50	YKL133C	Mitochondrial protein of unknown function	physical	1	1	1	Two-hybrid