Standard name Systematic name Name description Description
RCF1 YML030W Cytochrome c oxidase subunit Cytochrome c oxidase subunit; required for assembly of the Complex III-Complex IV supercomplex, and for assembly of Cox13p and Rcf2p into cytochrome c oxidase; similar to Rcf2p, and either Rcf1p or Rcf2p is required for late-stage assembly of the Cox12p and Cox13p subunits and for cytochrome c oxidase activity; required for growth under hypoxic conditions; member of the hypoxia induced gene family; C. elegans and human orthologs are functional in yeast
Visualize the interactome of RCF1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Endosome 0.059 NaN NaN
Mito 0.844 0.841 0.957
Vac/Vac Memb 0.250 0.155 0.071
Cell Periphery NaN 0.071 NaN
Golgi NaN 0.067 NaN
Bud NaN NaN 0.081

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RCF1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
COX1 Q0045 Subunit I of cytochrome c oxidase (Complex IV) physical 7 3 7 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Co-purification
COX3 Q0275 Subunit III of cytochrome c oxidase (Complex IV) physical 6 3 6 Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Reconstituted Complex, Co-purification
COX2 Q0250 Subunit II of cytochrome c oxidase (Complex IV) physical 6 4 5 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Co-purification
COR1 YBL045C Core subunit of the ubiquinol-cytochrome c reductase complex physical 6 3 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification
COX4 YGL187C Subunit IV of cytochrome c oxidase physical 5 2 4 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
CYT1 YOR065W Cytochrome c1 physical 5 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
IRA2 YOL081W GTPase-activating protein genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 4 1 4 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
RCF2 YNR018W Cytochrome c oxidase subunit genetic 3 2 2 Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
COB Q0105 Cytochrome b physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
RIP1 YEL024W Ubiquinol-cytochrome-c reductase physical 2 2 2 Affinity Capture-MS, Co-purification
SNF7 YLR025W One of four subunits of the ESCRT-III complex physical 2 2 2 Affinity Capture-MS, Two-hybrid
ATP11 YNL315C Molecular chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
PCF11 YDR228C mRNA 3' end processing factor genetic 2 1 2 Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
ATP5 YDR298C Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase genetic 2 1 2 Negative Genetic, Negative Genetic
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 2 1 2 Negative Genetic, Negative Genetic
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter genetic 2 1 2 Negative Genetic, Negative Genetic
ATP12 YJL180C Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase genetic 2 1 2 Negative Genetic, Negative Genetic
MCY1 YGR012W Putative cysteine synthase genetic 2 1 2 Negative Genetic, Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 2 1 2 Negative Genetic, Negative Genetic
DFG16 YOR030W Probable multiple transmembrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p genetic 2 1 2 Negative Genetic, Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
COX13 YGL191W Subunit VIa of cytochrome c oxidase physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
LSC2 YGR244C Beta subunit of succinyl-CoA ligase genetic 2 1 2 Negative Genetic, Negative Genetic
IRC15 YPL017C Microtubule associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SOR2 YDL246C Sorbitol dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 2 1 2 Negative Genetic, Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
VID28 YIL017C GID Complex subunit, serves as adaptor for regulatory subunit Vid24p genetic 2 1 2 Negative Genetic, Negative Genetic
YME2 YMR302C Integral inner mitochondrial membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 2 1 2 Negative Genetic, Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 2 1 2 Negative Genetic, Negative Genetic
SVL3 YPL032C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
PAU10 YDR542W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 2 1 1 Negative Genetic, Negative Genetic
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase genetic 2 1 1 Negative Genetic, Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 2 1 1 Negative Genetic, Negative Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 2 1 1 Positive Genetic, Positive Genetic
RCF2 YNR018W Cytochrome c oxidase subunit physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
RCF3 YBR255C-A Mitochondrial inner membrane protein physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 2 1 1 Negative Genetic, Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 2 1 1 Negative Genetic, Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 2 1 1 Negative Genetic, Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation physical 1 1 1 Two-hybrid
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
MUD1 YBR119W U1 snRNP A protein genetic 1 1 1 Positive Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Negative Genetic
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 genetic 1 1 1 Negative Genetic
HGH1 YGR187C Chaperone protein for translation factor eEF2 genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
CCA1 YER168C ATP (CTP):tRNA-specific tRNA nucleotidyltransferase genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
COX5A YNL052W Subunit Va of cytochrome c oxidase physical 1 1 1 Affinity Capture-MS
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) physical 1 1 1 Affinity Capture-MS
DYN1 YKR054C Cytoplasmic heavy chain dynein physical 1 1 1 Two-hybrid
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
AEP2 YMR282C Mitochondrial protein genetic 1 1 1 Negative Genetic
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 1 1 1 Negative Genetic
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
MAK3 YPR051W Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) genetic 1 1 1 Negative Genetic
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Positive Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
PAN2 YGL094C Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Negative Genetic
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Positive Genetic
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p genetic 1 1 1 Positive Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Negative Genetic
PNO1 YOR145C Essential nucleolar protein required for pre-18S rRNA processing genetic 1 1 1 Negative Genetic
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 1 1 1 Negative Genetic
NGL2 YMR285C Protein involved in 5.8S rRNA processing genetic 1 1 1 Negative Genetic
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 1 1 1 Negative Genetic
GSP1 YLR293C Ran GTPase genetic 1 1 1 Negative Genetic
HSH49 YOR319W U2-snRNP associated splicing factor genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Negative Genetic
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 1 1 1 Negative Genetic
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane genetic 1 1 1 Synthetic Growth Defect
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 1 1 1 Negative Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Negative Genetic
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 1 1 1 Positive Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Positive Genetic
LOS1 YKL205W Nuclear pore protein genetic 1 1 1 Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
ATP7 YKL016C Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
ADE2 YOR128C Phosphoribosylaminoimidazole carboxylase genetic 1 1 1 Negative Genetic
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Dosage Growth Defect
CLG1 YGL215W Cyclin-like protein that interacts with Pho85p genetic 1 1 1 Negative Genetic
ATG34 YOL083W Receptor protein involved in selective autophagy during starvation genetic 1 1 1 Negative Genetic
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex genetic 1 1 1 Negative Genetic
PEX14 YGL153W Central component of the peroxisomal importomer complex genetic 1 1 1 Negative Genetic
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
BLI1 YKL061W Subunit of the BLOC-1 complex involved in endosomal maturation genetic 1 1 1 Negative Genetic
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p genetic 1 1 1 Negative Genetic
HPC2 YBR215W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
MTR2 YKL186C mRNA transport regulator genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
RAV2 YDR202C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Negative Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Negative Genetic
MBF1 YOR298C-A Transcriptional coactivator genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
GAL1 YBR020W Galactokinase genetic 1 1 1 Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
PET122 YER153C Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Positive Genetic
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p physical 1 1 1 Two-hybrid
NNK1 YKL171W Protein kinase genetic 1 1 1 Negative Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
NIP100 YPL174C Large subunit of the dynactin complex physical 1 1 1 Two-hybrid
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Negative Genetic
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 1 1 1 Negative Genetic
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Positive Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
ERF2 YLR246W Subunit of a palmitoyltransferase genetic 1 1 1 Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
HOT13 YKL084W Zinc-binding mitochondrial intermembrane space (IMS) protein genetic 1 1 1 Negative Genetic
ARO8 YGL202W Aromatic aminotransferase I genetic 1 1 1 Negative Genetic
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Negative Genetic
HSP31 YDR533C Methylglyoxalase that converts methylglyoxal to D-lactate genetic 1 1 1 Negative Genetic
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription genetic 1 1 1 Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Positive Genetic
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
PMT5 YDL093W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
RAD30 YDR419W DNA polymerase eta genetic 1 1 1 Negative Genetic
IAI11 YBL059W Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
CUL3 YGR003W Ubiquitin-protein ligase genetic 1 1 1 Negative Genetic
PPT1 YGR123C Protein serine/threonine phosphatase genetic 1 1 1 Negative Genetic
MVB12 YGR206W ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers genetic 1 1 1 Negative Genetic
GUT1 YHL032C Glycerol kinase genetic 1 1 1 Negative Genetic
CYB5 YNL111C Cytochrome b5 physical 1 1 1 Co-purification
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
INM2 YDR287W Inositol monophosphatase genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
JID1 YPR061C Probable Hsp40p co-chaperone physical 1 1 1 Affinity Capture-MS
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b genetic 1 1 1 Negative Genetic
MIL1 YFL034W Predicted lipase genetic 1 1 1 Negative Genetic
AIM11 YER093C-A Protein of unknown function genetic 1 1 1 Negative Genetic
CYC3 YAL039C Cytochrome c heme lyase (holocytochrome c synthase) physical 1 1 1 Co-purification
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
AGE1 YDR524C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector genetic 1 1 1 Negative Genetic
PNT1 YOR266W Mitochondrial integral inner membrane protein genetic 1 1 1 Negative Genetic
POT1 YIL160C 3-ketoacyl-CoA thiolase with broad chain length specificity genetic 1 1 1 Negative Genetic
COX11 YPL132W Protein required for delivery of copper to Cox1p genetic 1 1 1 Phenotypic Enhancement
APE4 YHR113W Cytoplasmic aspartyl aminopeptidase with possible vacuole function genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
COX7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV) genetic 1 1 1 Positive Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Negative Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Positive Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Negative Genetic
BIG1 YHR101C Integral membrane protein of the endoplasmic reticulum genetic 1 1 1 Negative Genetic
FRT1 YOR324C Tail-anchored ER membrane protein of unknown function physical 1 1 1 Two-hybrid
GPI14 YJR013W Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I genetic 1 1 1 Negative Genetic
COX13 YGL191W Subunit VIa of cytochrome c oxidase genetic 1 1 1 Synthetic Growth Defect
COX12 YLR038C Subunit VIb of cytochrome c oxidase genetic 1 1 1 Positive Genetic
MIC60 YKR016W Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
MIC60 YKR016W Component of the MICOS complex genetic 1 1 1 Negative Genetic
APA2 YDR530C Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II genetic 1 1 1 Negative Genetic
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 1 1 1 Positive Genetic
COX8 YLR395C Subunit VIII of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
COX26 YDR119W-A Subunit of cytochrome C oxidase complex physical 1 1 1 Affinity Capture-Western
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Growth Defect
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Negative Genetic
MCH4 YOL119C Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Negative Genetic
MCO32 YGR053C Putative protein of unknown function genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
MIC10 YCL057C-A Conserved component of the MICOS complex physical 1 1 1 Affinity Capture-MS
HEM25 YDL119C Mitochondrial glycine transporter genetic 1 1 1 Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Negative Genetic
ALG8 YOR067C Glucosyl transferase genetic 1 1 1 Negative Genetic
COA6 YMR244C-A Protein involved in cytochrome c oxidase (Complex IV) assembly genetic 1 1 1 Negative Genetic
CIT3 YPR001W Dual specificity mitochondrial citrate and methylcitrate synthase genetic 1 1 1 Negative Genetic
FSH1 YHR049W Lysophospholipase genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
CTS2 YDR371W Putative chitinase genetic 1 1 1 Negative Genetic
AIM36 YMR157C Protein of unknown function genetic 1 1 1 Negative Genetic
SDH1 YKL148C Flavoprotein subunit of succinate dehydrogenase physical 1 1 1 Affinity Capture-MS
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
RCF1 YML030W Cytochrome c oxidase subunit physical 1 1 1 Affinity Capture-Western
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor physical 1 1 1 Two-hybrid
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways physical 1 1 1 Two-hybrid
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Two-hybrid
STE50 YCL032W Adaptor protein for various signaling pathways physical 1 1 1 Two-hybrid
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Positive Genetic
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 Two-hybrid
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 Two-hybrid
YAP1802 YGR241C Protein of the AP180 family, involved in clathrin cage assembly physical 1 1 1 Two-hybrid
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation physical 1 1 1 Two-hybrid
SMY1 YKL079W Kinesin-like myosin passenger-protein physical 1 1 1 Two-hybrid
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay physical 1 1 1 Two-hybrid
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Negative Genetic
SRO9 YCL037C Cytoplasmic RNA-binding protein genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes genetic 1 1 1 Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Positive Genetic
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
RPC53 YDL150W RNA polymerase III subunit C53 genetic 1 1 1 Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Positive Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
YJR120W YJR120W Protein of unknown function genetic 1 1 1 Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
SGE1 YPR198W Plasma membrane multidrug transporter genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Synthetic Growth Defect
YSY6 YBR162W-A Protein of unknown function genetic 1 1 1 Negative Genetic
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SBH1 YER087C-B Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) genetic 1 1 1 Negative Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Positive Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Positive Genetic
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes genetic 1 1 1 Positive Genetic
RSM24 YDR175C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Positive Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Positive Genetic
RPS29A YLR388W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit genetic 1 1 1 Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RRP12 YPL012W Protein required for export of the ribosomal subunits genetic 1 1 1 Negative Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 1 1 1 Negative Genetic
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex genetic 1 1 1 Negative Genetic
YBP1 YBR216C Protein involved in cellular response to oxidative stress genetic 1 1 1 Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
YBR298C-A YBR298C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TFB5 YDR079C-A Component of RNA polymerase II general transcription factor TFIIH genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RTS3 YGR161C Putative component of the protein phosphatase type 2A complex genetic 1 1 1 Negative Genetic
SOL4 YGR248W 6-phosphogluconolactonase genetic 1 1 1 Negative Genetic
YHR045W YHR045W Putative protein of unknown function genetic 1 1 1 Negative Genetic
UTR1 YJR049C ATP-NADH kinase genetic 1 1 1 Negative Genetic
YKR041W YKR041W Protein of unknown function genetic 1 1 1 Negative Genetic
SRP40 YKR092C Nucleolar serine-rich protein genetic 1 1 1 Negative Genetic
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
YMC2 YBR104W Putative mitochondrial inner membrane transporter genetic 1 1 1 Negative Genetic
VID24 YBR105C GID Complex regulatory subunit genetic 1 1 1 Negative Genetic
SLX1 YBR228W Endonuclease involved in DNA recombination and repair genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
TGL2 YDR058C Triacylglycerol lipase that is localized to the mitochondria genetic 1 1 1 Negative Genetic
YDR061W YDR061W Protein with similarity to ABC transporter family members genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
SDH7 YDR511W Mitochondrial protein involved in assembly of succinate dehydrogenase genetic 1 1 1 Negative Genetic
SPI1 YER150W GPI-anchored cell wall protein involved in weak acid resistance genetic 1 1 1 Negative Genetic
YER158C YER158C Protein of unknown function genetic 1 1 1 Negative Genetic
YMR31 YFR049W Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase genetic 1 1 1 Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RIE1 YGR250C RNA binding protein and negative regulator of START genetic 1 1 1 Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
TAX4 YJL083W EH domain-containing protein genetic 1 1 1 Negative Genetic
RPL17B YJL177W Ribosomal 60S subunit protein L17B genetic 1 1 1 Negative Genetic
VPS501 YKR078W Vacuolar SNX-BAR protein genetic 1 1 1 Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Negative Genetic
SPO75 YLL005C Meiosis-specific protein of unknown function genetic 1 1 1 Negative Genetic
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPL22A YLR061W Ribosomal 60S subunit protein L22A genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SCW10 YMR305C Cell wall protein with similarity to glucanases genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
TOM7 YNL070W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
YNL095C YNL095C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Negative Genetic
STD1 YOR047C Protein involved in control of glucose-regulated gene expression genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
LCL3 YGL085W Putative protein of unknown function genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic
FMT1 YBL013W Methionyl-tRNA formyltransferase genetic 1 1 1 Negative Genetic
ADF1 YCL058W-A Transcriptional repressor encoded by the FYV5 antisense strand genetic 1 1 1 Negative Genetic