Standard name Systematic name Name description Description
RAD30 YDR419W DNA polymerase eta DNA polymerase eta; involved in translesion synthesis during post-replication repair; catalyzes the synthesis of DNA opposite cyclobutane pyrimidine dimers and other lesions; involved in formation of post-replicative damage-induced genome-wide cohesion; may also have a role in protection against mitochondrial mutagenesis; may be involved in meiosis; mutations in human pol eta are responsible for XPV
Visualize the interactome of RAD30
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.167 0.160 0.343
Mito 0.283 NaN NaN
Nucleus 0.600 0.543 0.463
Vac/Vac Memb 0.242 0.481 0.194

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 1860

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RAD30 7 1 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
REV3 YPL167C Catalytic subunit of DNA polymerase zeta genetic 16 3 16 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) physical 15 4 13 Two-hybrid, Two-hybrid, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Protein-peptide, Co-crystal Structure
REV1 YOR346W Deoxycytidyl transferase physical 9 3 6 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Reconstituted Complex
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 8 4 7 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Rescue, Synthetic Growth Defect
REV1 YOR346W Deoxycytidyl transferase genetic 7 2 6 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Rescue, Phenotypic Enhancement
OGG1 YML060W Nuclear and mitochondrial glycosylase/lyase genetic 6 2 6 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 5 4 4 Phenotypic Enhancement, Synthetic Lethality, Synthetic Growth Defect, Synthetic Rescue, Synthetic Growth Defect
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 5 2 4 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Enhancement
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 4 2 4 Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect
RNH201 YNL072W Ribonuclease H2 catalytic subunit genetic 4 2 3 Synthetic Lethality, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
LSM12 YHR121W Protein of unknown function that may function in RNA processing physical 4 3 2 Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western
UBI4 YLL039C Ubiquitin physical 3 3 3 Two-hybrid, Reconstituted Complex, Co-crystal Structure
POL32 YJR043C Third subunit of DNA polymerase delta genetic 3 3 2 Phenotypic Enhancement, Synthetic Lethality, Synthetic Growth Defect
RNH1 YMR234W Ribonuclease H1 genetic 3 2 2 Synthetic Lethality, Synthetic Rescue, Synthetic Rescue
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MSS18 YPR134W Nuclear encoded protein needed for splicing of mitochondrial intron genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MTO1 YGL236C Mitochondrial protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MSH6 YDR097C Protein required for mismatch repair in mitosis and meiosis genetic 2 2 2 Dosage Lethality, Phenotypic Enhancement
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
UBC13 YDR092W E2 ubiquitin-conjugating enzyme genetic 2 2 2 Synthetic Growth Defect, Phenotypic Enhancement
MAG1 YER142C 3-methyl-adenine DNA glycosylase genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
FUI1 YBL042C High affinity uridine permease, localizes to the plasma membrane genetic 2 1 2 Negative Genetic, Negative Genetic
MDV1 YJL112W Peripheral protein of cytosolic face of mitochondrial outer membrane genetic 2 1 2 Negative Genetic, Negative Genetic
MGA1 YGR249W Protein similar to heat shock transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
INP1 YMR204C Peripheral membrane protein of peroxisomes genetic 2 1 2 Negative Genetic, Negative Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
RRT6 YGL146C Integral membrane protein, member of the p24 family genetic 2 1 2 Negative Genetic, Negative Genetic
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
DIA1 YMR316W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
RAD18 YCR066W E3 ubiquitin ligase physical 2 2 1 Two-hybrid, Protein-peptide
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 2 1 1 Negative Genetic, Negative Genetic
YMD8 YML038C Putative nucleotide sugar transporter genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Positive Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
PSY2 YNL201C Subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Phenotypic Suppression
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Positive Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Biochemical Activity
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Negative Genetic
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Synthetic Growth Defect
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Negative Genetic
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRH4 YGL064C Mitochondrial ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 PCA
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Phenotypic Enhancement
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Phenotypic Enhancement
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions genetic 1 1 1 Phenotypic Suppression
MGS1 YNL218W Protein with DNA-dependent ATPase and ssDNA annealing activities genetic 1 1 1 Synthetic Rescue
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex physical 1 1 1 Affinity Capture-MS
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Negative Genetic
FUN30 YAL019W Snf2p family member with ATP-dependent chromatin remodeling activity genetic 1 1 1 Synthetic Rescue
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Phenotypic Enhancement
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
HTB1 YDR224C Histone H2B genetic 1 1 1 Phenotypic Enhancement
DDC1 YPL194W DNA damage checkpoint protein genetic 1 1 1 Synthetic Growth Defect
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
RAD18 YCR066W E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
ISN1 YOR155C Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase genetic 1 1 1 Negative Genetic
MER1 YNL210W mRNA-binding protein required for meiosis-specific mRNA splicing genetic 1 1 1 Negative Genetic
DEF1 YKL054C RNAPII degradation factor genetic 1 1 1 Synthetic Growth Defect
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Synthetic Growth Defect
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Lethality
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease genetic 1 1 1 Phenotypic Enhancement
ECO1 YFR027W Acetyltransferase required for sister chromatid cohesion physical 1 1 1 Biochemical Activity
ECO1 YFR027W Acetyltransferase required for sister chromatid cohesion genetic 1 1 1 Synthetic Growth Defect
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta physical 1 1 1 Affinity Capture-MS
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) physical 1 1 1 Affinity Capture-MS
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation genetic 1 1 1 Negative Genetic
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 1 1 1 Phenotypic Enhancement
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase genetic 1 1 1 Negative Genetic
DSE1 YER124C Daughter cell-specific protein genetic 1 1 1 Negative Genetic
PET494 YNR045W Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
HRI1 YLR301W Protein of unknown function that interacts with Sec72p and Hrr25p genetic 1 1 1 Negative Genetic
ERF2 YLR246W Subunit of a palmitoyltransferase genetic 1 1 1 Negative Genetic
PIN3 YPR154W Negative regulator of actin nucleation-promoting factor activity genetic 1 1 1 Negative Genetic
MIG2 YGL209W Zinc finger transcriptional repressor genetic 1 1 1 Negative Genetic
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Affinity Capture-MS
SNU13 YEL026W RNA binding protein physical 1 1 1 Affinity Capture-MS
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex physical 1 1 1 Affinity Capture-MS
RBS1 YDL189W Protein involved in assembly of the RNA Pol III complex physical 1 1 1 PCA
TVP23 YDR084C Integral membrane protein physical 1 1 1 PCA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RAD5 YLR032W DNA helicase/Ubiquitin ligase physical 1 1 1 Two-hybrid
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Protein-peptide
REV3 YPL167C Catalytic subunit of DNA polymerase zeta physical 1 1 1 Affinity Capture-MS
REV7 YIL139C Accessory subunit of DNA polymerase zeta physical 1 1 1 Affinity Capture-MS
REV7 YIL139C Accessory subunit of DNA polymerase zeta genetic 1 1 1 Phenotypic Enhancement
RAD55 YDR076W Protein that stimulates strand exchange genetic 1 1 1 Synthetic Growth Defect
YHP1 YDR451C Homeobox transcriptional repressor genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Positive Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Positive Genetic
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Phenotypic Enhancement
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes genetic 1 1 1 Phenotypic Enhancement
SIZ1 YDR409W SUMO E3 ligase genetic 1 1 1 Synthetic Growth Defect
VCX1 YDL128W Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity genetic 1 1 1 Negative Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 1 1 1 Negative Genetic
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 1 1 1 Synthetic Growth Defect
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 1 1 1 Synthetic Growth Defect
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Synthetic Growth Defect
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Lethality
RAD51 YER095W Strand exchange protein genetic 1 1 1 Synthetic Growth Defect
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Synthetic Growth Defect
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Synthetic Growth Defect
RSM19 YNR037C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Negative Genetic
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex genetic 1 1 1 Negative Genetic
TEP1 YNL128W PTEN homolog with no demonstrated inositol lipid phosphatase activity genetic 1 1 1 Negative Genetic
YER079W YER079W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YIL024C YIL024C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RCF1 YML030W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
RPL20A YMR242C Ribosomal 60S subunit protein L20A genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
YNL208W YNL208W Protein of unknown function genetic 1 1 1 Negative Genetic
RPL18B YNL301C Ribosomal 60S subunit protein L18B genetic 1 1 1 Negative Genetic
YOR012W YOR012W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOR186W YOR186W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Synthetic Growth Defect
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 1 1 1 Synthetic Growth Defect
CUL3 YGR003W Ubiquitin-protein ligase genetic 1 1 1 Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
MRPL22 YNL177C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
PMS1 YNL082W ATP-binding protein required for mismatch repair genetic 1 1 1 Dosage Lethality
OTU2 YHL013C Protein of unknown function genetic 1 1 1 Negative Genetic
PDE1 YGL248W Low-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic
HLJ1 YMR161W Co-chaperone for Hsp40p physical 1 1 1 PCA
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly genetic 1 1 1 Negative Genetic
CMC2 YBL059C-A Protein involved in respiratory chain complex assembly or maintenance genetic 1 1 1 Negative Genetic
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Synthetic Growth Defect
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3 genetic 1 1 1 Negative Genetic
HIM1 YDR317W Protein of unknown function involved in DNA repair genetic 1 1 1 Phenotypic Suppression
ADY2 YCR010C Acetate transporter required for normal sporulation genetic 1 1 1 Negative Genetic
DAL4 YIR028W Allantoin permease genetic 1 1 1 Negative Genetic
MTC4 YBR255W Protein of unknown function genetic 1 1 1 Negative Genetic