Standard name Systematic name Name description Description
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase Mitochondrial acetyl-coenzyme A carboxylase; catalyzes production of malonyl-CoA in mitochondrial fatty acid biosynthesis; relocalizes from mitochondrion to cytoplasm upon DNA replication stress; genetic and comparative analysis suggests that translation begins at a non-canonical (Ile) start codon at -372 relative to the annotated start codon
Visualize the interactome of HFA1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cort. Patches 0.067 NaN NaN
Cytoplasm 0.181 0.412 0.393
ER 0.067 NaN NaN
Endosome 0.201 0.077 0.053
Mito 0.215 0.383 0.427
SpindlePole 0.201 0.077 0.161
Vac/Vac Memb 0.134 0.128 NaN
Peroxisome NaN 0.071 NaN
Bud NaN NaN 0.093

GFP localization & abundance

GFP localization GFP abundance
ambiguous, mitochondrion 396

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HFA1 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0108 (acetyl-Coa carboxylase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ALD5 YER073W Mitochondrial aldehyde dehydrogenase genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
THR4 YCR053W Threonine synthase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CTP1 YBR291C Mitochondrial inner membrane citrate transporter genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 3 1 3 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
MCX1 YBR227C Non-proteolytic ATPase of the AAA family genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 2 2 2 Negative Genetic, Positive Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 2 2 2 Negative Genetic, Positive Genetic
ATP11 YNL315C Molecular chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 2 1 2 Negative Genetic, Negative Genetic
APL4 YPR029C Gamma-adaptin genetic 2 1 2 Positive Genetic, Positive Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 2 1 2 Positive Genetic, Positive Genetic
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
HPT1 YDR399W Dimeric hypoxanthine-guanine phosphoribosyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response genetic 2 1 2 Positive Genetic, Positive Genetic
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 2 1 2 Positive Genetic, Positive Genetic
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 2 1 2 Negative Genetic, Negative Genetic
PDX1 YGR193C E3-binding protein of the mitochondrial pyruvate dehydrogenase complex genetic 2 1 2 Negative Genetic, Negative Genetic
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases genetic 2 1 2 Negative Genetic, Negative Genetic
SER1 YOR184W 3-phosphoserine aminotransferase genetic 2 1 2 Negative Genetic, Negative Genetic
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 2 1 2 Negative Genetic, Negative Genetic
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 2 1 2 Negative Genetic, Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase genetic 2 1 1 Negative Genetic, Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
CIT1 YNR001C Mitochondrial citrate synthase genetic 2 1 1 Positive Genetic, Positive Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 2 1 1 Positive Genetic, Positive Genetic
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Negative Genetic
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing genetic 1 1 1 Negative Genetic
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 Affinity Capture-MS
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme physical 1 1 1 Affinity Capture-MS
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Positive Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Affinity Capture-MS
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 1 1 1 Positive Genetic
ATP22 YDR350C Specific translational activator for the mitochondrial ATP6 mRNA genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase physical 1 1 1 Affinity Capture-MS
CSN9 YDR179C Subunit of the Cop9 signalosome genetic 1 1 1 Positive Genetic
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
DIA4 YHR011W Probable mitochondrial seryl-tRNA synthetase genetic 1 1 1 Positive Genetic
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) genetic 1 1 1 Negative Genetic
GRH1 YDR517W Acetylated cis-Golgi protein, homolog of human GRASP65 genetic 1 1 1 Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Negative Genetic
ADK1 YDR226W Adenylate kinase, required for purine metabolism genetic 1 1 1 Negative Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 1 1 1 Negative Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Positive Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Positive Genetic
DAP1 YPL170W Heme-binding protein genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
CRC1 YOR100C Mitochondrial inner membrane carnitine transporter genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Positive Genetic
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Positive Genetic
ATP20 YPR020W Subunit g of the mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
BIL2 YGL015C Formin inhibitor genetic 1 1 1 Negative Genetic
CIT2 YCR005C Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle genetic 1 1 1 Negative Genetic
GDH1 YOR375C NADP(+)-dependent glutamate dehydrogenase genetic 1 1 1 Positive Genetic
ACO2 YJL200C Putative mitochondrial aconitase isozyme genetic 1 1 1 Negative Genetic
ATG39 YLR312C Transmembrane receptor with a role in nucleophagy genetic 1 1 1 Negative Genetic
BMT2 YBR141C Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Positive Genetic
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
ELO3 YLR372W Elongase genetic 1 1 1 Synthetic Rescue
LSM2 YBL026W Lsm (Like Sm) protein physical 1 1 1 Two-hybrid
LSM2 YBL026W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
HGH1 YGR187C Chaperone protein for translation factor eEF2 physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
HXK1 YFR053C Hexokinase isoenzyme 1 genetic 1 1 1 Positive Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
TUB3 YML124C Alpha-tubulin genetic 1 1 1 Negative Genetic
URK1 YNR012W Uridine/cytidine kinase genetic 1 1 1 Positive Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
YDR124W YDR124W Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
RAD30 YDR419W DNA polymerase eta genetic 1 1 1 Negative Genetic
SDD1 YEL057C Protein of unknown function genetic 1 1 1 Negative Genetic
UBC8 YEL012W Ubiquitin-conjugating enzyme that regulates gluconeogenesis genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Positive Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Negative Genetic
YUR1 YJL139C Mannosyltransferase involved in protein N-glycosylation genetic 1 1 1 Negative Genetic
LEU1 YGL009C Isopropylmalate isomerase genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Positive Genetic
IAH1 YOR126C Isoamyl acetate-hydrolyzing esterase genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
UTR1 YJR049C ATP-NADH kinase genetic 1 1 1 Positive Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Positive Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 1 1 1 Negative Genetic
RBK1 YCR036W Ribokinase, phosphorylates ribose to ribose-5-phosphate genetic 1 1 1 Positive Genetic
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Positive Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Synthetic Growth Defect
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Positive Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Positive Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Positive Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Positive Genetic
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Positive Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Positive Genetic
NKP1 YDR383C Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Positive Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Positive Genetic
QRI5 YLR204W Mitochondrial inner membrane protein genetic 1 1 1 Positive Genetic
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p genetic 1 1 1 Positive Genetic
HNT1 YDL125C Adenosine 5'-monophosphoramidase genetic 1 1 1 Positive Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Positive Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Positive Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Positive Genetic
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Positive Genetic
RTC6 YPL183W-A Protein involved in translation genetic 1 1 1 Positive Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Positive Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
NOP19 YGR251W Ribosome biogenesis factor genetic 1 1 1 Negative Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 1 1 1 Negative Genetic
PAM18 YLR008C Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
ILV5 YLR355C Acetohydroxyacid reductoisomerase and mtDNA binding protein genetic 1 1 1 Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
SPC29 YPL124W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Negative Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
UTP6 YDR449C Nucleolar protein genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
TBF1 YPL128C Telobox-containing general regulatory factor genetic 1 1 1 Negative Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 1 1 1 Negative Genetic
PDX3 YBR035C Pyridoxine (pyridoxamine) phosphate oxidase genetic 1 1 1 Negative Genetic
TYR1 YBR166C Prephenate dehydrogenase involved in tyrosine biosynthesis genetic 1 1 1 Negative Genetic
MRPL32 YCR003W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
IPF1 YDL176W Protein of unknown function involved in actin patch formation genetic 1 1 1 Negative Genetic
YER187W YER187W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR121W-A YGR121W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
XKS1 YGR194C Xylulokinase genetic 1 1 1 Negative Genetic
YGR210C YGR210C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YHR140W YHR140W Endoplasmic reticulum protein genetic 1 1 1 Negative Genetic
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
PMT4 YJR143C Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
URA1 YKL216W Dihydroorotate dehydrogenase genetic 1 1 1 Negative Genetic
YKR041W YKR041W Protein of unknown function genetic 1 1 1 Negative Genetic
NHA1 YLR138W Na+/H+ antiporter genetic 1 1 1 Negative Genetic
UBC12 YLR306W Enzyme that mediates the conjugation of Rub1p genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
RTC2 YBR147W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Negative Genetic
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
SHM1 YBR263W Mitochondrial serine hydroxymethyltransferase genetic 1 1 1 Negative Genetic
YBR284W YBR284W Putative metallo-dependent hydrolase superfamily protein genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
SPS2 YDR522C Protein expressed during sporulation genetic 1 1 1 Negative Genetic
HSP12 YFL014W Plasma membrane protein involved in maintaining membrane organization genetic 1 1 1 Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MTO1 YGL236C Mitochondrial protein genetic 1 1 1 Negative Genetic
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RSR1 YGR152C Ras-type GTPase genetic 1 1 1 Negative Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
YHB1 YGR234W Nitric oxide oxidoreductase genetic 1 1 1 Negative Genetic
RIM4 YHL024W Putative RNA-binding protein genetic 1 1 1 Negative Genetic
OSH3 YHR073W Member of an oxysterol-binding protein family genetic 1 1 1 Negative Genetic
SOL3 YHR163W 6-phosphogluconolactonase genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
MET28 YIR017C bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
PIR5 YJL160C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SRL3 YKR091W Repressor of transcription at Start genetic 1 1 1 Negative Genetic
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
TAG1 YLR173W Vacuolar membrane protein involved in termination of autophagy genetic 1 1 1 Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Negative Genetic
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Negative Genetic
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p genetic 1 1 1 Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
MCP1 YOR228C Mitochondrial protein of unknown function involved in lipid homeostas genetic 1 1 1 Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Negative Genetic
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA genetic 1 1 1 Negative Genetic
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
LTP1 YPR073C Protein phosphotyrosine phosphatase of unknown cellular role genetic 1 1 1 Negative Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
PEX17 YNL214W Membrane peroxin of the peroxisomal importomer complex genetic 1 1 1 Negative Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
PHA2 YNL316C Prephenate dehydratase genetic 1 1 1 Negative Genetic
YNR048W YNR048W Potential noncatalytic subunit for phospholipid translocase Dnf3p genetic 1 1 1 Negative Genetic
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Positive Genetic
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 1 1 1 Negative Genetic
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
PMS1 YNL082W ATP-binding protein required for mismatch repair genetic 1 1 1 Positive Genetic
RPL11A YPR102C Ribosomal 60S subunit protein L11A genetic 1 1 1 Positive Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Negative Genetic
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin genetic 1 1 1 Positive Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
MSH1 YHR120W DNA-binding protein of the mitochondria genetic 1 1 1 Positive Genetic
LST7 YGR057C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Positive Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Positive Genetic
IRA1 YBR140C GTPase-activating protein genetic 1 1 1 Negative Genetic
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) genetic 1 1 1 Positive Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
PEX12 YMR026C C3HC4-type RING-finger peroxin and E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
BCS1 YDR375C Protein translocase and chaperone required for Complex III assembly genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
EHT1 YBR177C Octanoyl-CoA:ethanol acyltransferase genetic 1 1 1 Negative Genetic
COQ10 YOL008W Coenzyme Q (ubiquinone) binding protein genetic 1 1 1 Negative Genetic
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
FAS1 YKL182W Beta subunit of fatty acid synthetase physical 1 1 1 Affinity Capture-MS
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b genetic 1 1 1 Negative Genetic
HEM1 YDR232W 5-aminolevulinate synthase genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
BAP2 YBR068C High-affinity leucine permease genetic 1 1 1 Negative Genetic
DUR3 YHL016C Plasma membrane transporter for both urea and polyamines genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Positive Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Negative Genetic
GPI14 YJR013W Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I genetic 1 1 1 Negative Genetic
FCY22 YER060W-A Putative purine-cytosine permease genetic 1 1 1 Negative Genetic
COX9 YDL067C Subunit VIIa of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 1 1 1 Phenotypic Enhancement
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Negative Genetic
DPC25 YPL107W Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
GSH2 YOL049W Glutathione synthetase genetic 1 1 1 Negative Genetic
HEM25 YDL119C Mitochondrial glycine transporter genetic 1 1 1 Negative Genetic
ERG8 YMR220W Phosphomevalonate kinase genetic 1 1 1 Phenotypic Enhancement