Standard name Systematic name Name description Description
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in lipid metabolism Phospholipase B (lysophospholipase) involved in lipid metabolism; hydrolyzes phosphatidylinositol and phosphatidylserine and displays transacylase activity in vitro; PLB3 has a paralog, PLB1, that arose from the whole genome duplication
Visualize the interactome of PLB3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 157

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.775 0.748 0.671
Vac/Vac Memb 0.258 0.158 0.207
ER NaN 0.062 0.055
Mito NaN 0.102 0.055
Endosome NaN NaN 0.114

GFP localization & abundance

GFP localization GFP abundance
vacuole low signal

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PLB3 4 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_3059 (PS phospholipase B (1-16:1, 2-16:1), cell envelope), r_3064 (PS phospholipase B (1-18:0, 2-18:1), cell envelope), r_3065 (PS phospholipase B (1-18:1, 2-18:1), cell envelope), r_3071 (PI phospholipase B (1-16:1, 2-16:1), cell envelope), r_3062 (PS phospholipase B (1-16:0, 2-18:1), cell envelope), r_3068 (LPS phospholipase B (18:0), cell envelope), r_3074 (PI phospholipase B (1-16:0, 2-18:1), cell envelope), r_3077 (PI phospholipase B (1-18:1, 2-18:1), cell envelope), r_3080 (LPI phospholipase B (18:0), cell envelope), r_3060 (PS phospholipase B (1-18:0, 2-16:1), cell envelope), r_3066 (LPS phospholipase B (16:0), cell envelope), r_3072 (PI phospholipase B (1-18:0, 2-16:1), cell envelope), r_3078 (LPI phospholipase B (16:0), cell envelope), r_3063 (PS phospholipase B (1-16:1, 2-18:1), cell envelope), r_3069 (LPS phospholipase B (18:1), cell envelope), r_3075 (PI phospholipase B (1-16:1, 2-18:1), cell envelope), r_3081 (LPI phospholipase B (18:1), cell envelope), r_3061 (PS phospholipase B (1-18:1, 2-16:1), cell envelope), r_3067 (LPS phospholipase B (16:1), cell envelope), r_3058 (PS phospholipase B (1-16:0, 2-16:1), cell envelope), r_3076 (PI phospholipase B (1-18:0, 2-18:1), cell envelope), r_3073 (PI phospholipase B (1-18:1, 2-16:1), cell envelope), r_3070 (PI phospholipase B (1-16:0, 2-16:1), cell envelope), r_3079 (LPI phospholipase B (16:1), cell envelope)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
RSB1 YOR049C Sphingoid long-chain base (LCB) efflux transporter genetic 3 2 3 Phenotypic Enhancement, Negative Genetic, Negative Genetic
INM1 YHR046C Inositol monophosphatase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
CWC15 YDR163W Non-essential protein involved in pre-mRNA splicing genetic 2 1 2 Negative Genetic, Negative Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 2 1 2 Negative Genetic, Negative Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 2 1 2 Negative Genetic, Negative Genetic
YDR248C YDR248C Putative gluconokinase genetic 2 1 2 Negative Genetic, Negative Genetic
PUF6 YDR496C Pumilio-homology domain protein genetic 2 1 2 Negative Genetic, Negative Genetic
PYC1 YGL062W Pyruvate carboxylase isoform genetic 2 1 2 Negative Genetic, Negative Genetic
STF2 YGR008C Protein involved in resistance to desiccation stress genetic 2 1 2 Negative Genetic, Negative Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 2 1 2 Negative Genetic, Negative Genetic
MXR1 YER042W Methionine-S-sulfoxide reductase genetic 2 1 2 Negative Genetic, Negative Genetic
IMA5 YJL216C Alpha-glucosidase genetic 2 1 2 Negative Genetic, Negative Genetic
PEX18 YHR160C Peroxin genetic 2 1 1 Negative Genetic, Negative Genetic
BCS1 YDR375C Protein translocase and chaperone required for Complex III assembly genetic 2 1 1 Negative Genetic, Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 2 1 1 Positive Genetic, Positive Genetic
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit genetic 2 1 1 Negative Genetic, Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 2 1 1 Negative Genetic, Negative Genetic
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 DNA to cDNA expression microarray evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SKN7 YHR206W Nuclear response regulator and transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Negative Genetic
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
APL3 YBL037W Alpha-adaptin genetic 1 1 1 Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Negative Genetic
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
DHR2 YKL078W Predominantly nucleolar DEAH-box ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Positive Genetic
NDL1 YLR254C Homolog of nuclear distribution factor NudE genetic 1 1 1 Negative Genetic
AKR2 YOR034C Ankyrin repeat-containing protein genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
PEP12 YOR036W Target membrane receptor (t-SNARE) genetic 1 1 1 Negative Genetic
CRP1 YHR146W Protein that binds to cruciform DNA structures genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
ERG25 YGR060W C-4 methyl sterol oxidase genetic 1 1 1 Positive Genetic
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase genetic 1 1 1 Negative Genetic
ATC1 YDR184C Nuclear protein genetic 1 1 1 Negative Genetic
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Negative Genetic
PET122 YER153C Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Two-hybrid
SUP35 YDR172W Translation termination factor eRF3 physical 1 1 1 Affinity Capture-MS
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
VBA4 YDR119W Protein of unknown function genetic 1 1 1 Negative Genetic
TPC1 YGR096W Mitochondrial membrane transporter genetic 1 1 1 Negative Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 1 1 1 Negative Genetic
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 1 1 1 Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Negative Genetic
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis genetic 1 1 1 Negative Genetic
SEG1 YMR086W Component of eisosome required for proper eisosome assembly genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Positive Genetic
YCR090C YCR090C Putative protein of unknown function genetic 1 1 1 Positive Genetic
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
PRE8 YML092C Alpha 2 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RIP1 YEL024W Ubiquinol-cytochrome-c reductase genetic 1 1 1 Negative Genetic
RPO41 YFL036W Mitochondrial RNA polymerase genetic 1 1 1 Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
YGL036W YGL036W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) genetic 1 1 1 Negative Genetic
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Negative Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Dosage Rescue
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Negative Genetic
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Positive Genetic
DIN7 YDR263C Mitochondrial nuclease functioning in DNA repair and replication genetic 1 1 1 Negative Genetic
OSM1 YJR051W Fumarate reductase, catalyzes the reduction of fumarate to succinate genetic 1 1 1 Negative Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Synthetic Rescue
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
PLB2 YMR006C Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Dosage Rescue