Standard name Systematic name Name description Description
ERG25 YGR060W C-4 methyl sterol oxidase C-4 methyl sterol oxidase; catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol; human MSMO1 functionally complements the growth defect caused by repression of ERG25 expression
Visualize the interactome of ERG25
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.681 0.491 0.255
ER 0.159 0.451 0.646
Vac/Vac Memb 0.188 0.065 0.132

GFP localization & abundance

GFP localization GFP abundance
ER, vacuole 77100

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ERG25 3 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0241 (C-4 sterol methyl oxidase (4,4-dimethylzymosterol)), r_0239 (C-4 methyl sterol oxidase), r_0240 (C-4 methyl sterol oxidase), r_0238 (C-4 methyl sterol oxidase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
STE24 YJR117W Highly conserved zinc metalloprotease genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CUE1 YMR264W Ubiquitin-binding protein genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERG28 YER044C Endoplasmic reticulum membrane protein physical 5 3 3 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, PCA, PCA
ERG27 YLR100W 3-keto sterol reductase physical 4 3 3 Two-hybrid, Affinity Capture-Western, PCA, PCA
MSC7 YHR039C Protein of unknown function genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UBC7 YMR022W Ubiquitin conjugating enzyme genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 3 2 3 PCA, PCA, Affinity Capture-MS
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase physical 3 1 2 PCA, PCA, PCA
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase physical 3 1 2 PCA, PCA, PCA
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GDA1 YEL042W Guanosine diphosphatase located in the Golgi genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ERG2 YMR202W C-8 sterol isomerase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ERG26 YGL001C C-3 sterol dehydrogenase physical 2 2 2 Two-hybrid, PCA
YMR226C YMR226C NADP(+)-dependent serine dehydrogenase and carbonyl reductase genetic 2 2 2 Positive Genetic, Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 2 2 2 Positive Genetic, Negative Genetic
ARF1 YDL192W ADP-ribosylation factor genetic 2 1 2 Negative Genetic, Negative Genetic
ERG1 YGR175C Squalene epoxidase physical 2 1 2 PCA, PCA
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 2 1 2 Negative Genetic, Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p physical 2 1 2 PCA, PCA
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein physical 2 1 2 PCA, PCA
ERG25 YGR060W C-4 methyl sterol oxidase physical 2 1 2 PCA, PCA
ERG5 YMR015C C-22 sterol desaturase genetic 2 1 2 Positive Genetic, Positive Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 2 1 2 Negative Genetic, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 2 1 2 Negative Genetic, Negative Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 2 Negative Genetic, Negative Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 2 1 2 Negative Genetic, Negative Genetic
URA5 YML106W Major orotate phosphoribosyltransferase (OPRTase) isozyme genetic 2 1 2 Negative Genetic, Negative Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 2 1 2 Positive Genetic, Positive Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 2 1 2 Positive Genetic, Positive Genetic
FUM1 YPL262W Fumarase genetic 2 1 2 Negative Genetic, Negative Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 2 1 2 Positive Genetic, Positive Genetic
LCB3 YJL134W Long-chain base-1-phosphate phosphatase genetic 2 1 2 Positive Genetic, Positive Genetic
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 2 1 2 Negative Genetic, Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 2 1 2 Negative Genetic, Negative Genetic
FRQ1 YDR373W N-myristoylated calcium-binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
SEC4 YFL005W Rab family GTPase genetic 2 1 2 Negative Genetic, Negative Genetic
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase physical 2 1 2 PCA, PCA
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 2 1 2 Negative Genetic, Negative Genetic
ANY1 YMR010W Protein involved in phospholipid flippase function genetic 2 1 2 Negative Genetic, Negative Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 2 1 2 Negative Genetic, Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 2 1 1 Negative Genetic, Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase physical 2 1 1 PCA, PCA
INP54 YOL065C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 2 1 1 Negative Genetic, Negative Genetic
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 2 1 1 Negative Genetic, Negative Genetic
YDR476C YDR476C Putative protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
NTE1 YML059C Serine esterase genetic 2 1 1 Negative Genetic, Negative Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Negative Genetic, Negative Genetic
YPS1 YLR120C Aspartic protease genetic 2 1 1 Positive Genetic, Positive Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HAP1 YLR256W Zinc finger transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NDD1 YOR372C Transcriptional activator essential for nuclear division regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Negative Genetic
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
ATG14 YBR128C Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I genetic 1 1 1 Negative Genetic
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
CIA2 YHR122W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
EMP24 YGL200C Component of the p24 complex physical 1 1 1 PCA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
CSI1 YMR025W Subunit of the Cop9 signalosome genetic 1 1 1 Negative Genetic
AVT4 YNL101W Vacuolar transporter physical 1 1 1 PCA
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Positive Genetic
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) genetic 1 1 1 Negative Genetic
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Negative Genetic
CNB1 YKL190W Calcineurin B genetic 1 1 1 Negative Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Negative Genetic
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone genetic 1 1 1 Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Negative Genetic
ARF2 YDL137W ADP-ribosylation factor genetic 1 1 1 Negative Genetic
EPT1 YHR123W sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase physical 1 1 1 PCA
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 1 1 1 Synthetic Rescue
ATP5 YDR298C Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
CDC26 YFR036W Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
AMD1 YML035C AMP deaminase genetic 1 1 1 Positive Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis physical 1 1 1 PCA
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Positive Genetic
ELO3 YLR372W Elongase physical 1 1 1 PCA
EMC5 YIL027C Member of conserved ER transmembrane complex physical 1 1 1 PCA
CHS3 YBR023C Chitin synthase III genetic 1 1 1 Negative Genetic
ERG27 YLR100W 3-keto sterol reductase genetic 1 1 1 Negative Genetic
ERP1 YAR002C-A Member of the p24 family involved in ER to Golgi transport physical 1 1 1 PCA
SND3 YBR106W Involved in SRP-independent protein targeting to the ER genetic 1 1 1 Negative Genetic
VVS1 YBR241C Putative transporter, member of the sugar porter family physical 1 1 1 PCA
SSH1 YBR283C Subunit of the Ssh1 translocon complex physical 1 1 1 PCA
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport physical 1 1 1 PCA
ORM2 YLR350W Protein that mediates sphingolipid homeostasis physical 1 1 1 PCA
SPC2 YML055W Subunit of signal peptidase complex physical 1 1 1 PCA
ILM1 YJR118C Protein of unknown function physical 1 1 1 PCA
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
RBD2 YPL246C Possible rhomboid protease physical 1 1 1 PCA
ERG29 YMR134W Protein of unknown function involved in ergosterol biosynthesis physical 1 1 1 PCA
ERG29 YMR134W Protein of unknown function involved in ergosterol biosynthesis genetic 1 1 1 Dosage Rescue
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 PCA
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ERG4 YGL012W C-24(28) sterol reductase physical 1 1 1 PCA
ERG5 YMR015C C-22 sterol desaturase physical 1 1 1 PCA
ERG7 YHR072W Lanosterol synthase physical 1 1 1 PCA
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) physical 1 1 1 PCA
YPC1 YBR183W Alkaline ceramidase physical 1 1 1 PCA
ERP2 YAL007C Member of the p24 family involved in ER to Golgi transport physical 1 1 1 PCA
UIP3 YAR027W Putative integral membrane protein of unknown function physical 1 1 1 PCA
IFA38 YBR159W Microsomal beta-keto-reductase physical 1 1 1 PCA
TSC13 YDL015C Enoyl reductase physical 1 1 1 PCA
SHR3 YDL212W Endoplasmic reticulum packaging chaperone physical 1 1 1 PCA
SHR3 YDL212W Endoplasmic reticulum packaging chaperone genetic 1 1 1 Negative Genetic
HXT6 YDR343C High-affinity glucose transporter physical 1 1 1 PCA
PMP2 YEL017C-A Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p) physical 1 1 1 PCA
MST27 YGL051W Putative integral membrane protein, involved in vesicle formation physical 1 1 1 PCA
VMA21 YGR105W Integral membrane protein required for V-ATPase function physical 1 1 1 PCA
ERV29 YGR284C Protein localized to COPII-coated vesicles physical 1 1 1 PCA
LAG1 YHL003C Ceramide synthase component physical 1 1 1 PCA
YHR140W YHR140W Endoplasmic reticulum protein physical 1 1 1 PCA
SNL1 YIL016W Ribosome-associated protein physical 1 1 1 PCA
TRK1 YJL129C Component of the Trk1p-Trk2p potassium transport system physical 1 1 1 PCA
STE24 YJR117W Highly conserved zinc metalloprotease physical 1 1 1 PCA
LAC1 YKL008C Ceramide synthase component physical 1 1 1 PCA
YET1 YKL065C Endoplasmic reticulum transmembrane protein physical 1 1 1 PCA
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit physical 1 1 1 PCA
TVP38 YKR088C Integral membrane protein physical 1 1 1 PCA
SPO75 YLL005C Meiosis-specific protein of unknown function physical 1 1 1 PCA
GAS2 YLR343W 1,3-beta-glucanosyltransferase physical 1 1 1 PCA
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein physical 1 1 1 PCA
HMG1 YML075C HMG-CoA reductase physical 1 1 1 PCA
GAS3 YMR215W Putative 1,3-beta-glucanosyltransferase physical 1 1 1 PCA
PFA4 YOL003C Palmitoyltransferase with autoacylation activity physical 1 1 1 PCA
ERP4 YOR016C Member of the p24 family involved in ER to Golgi transport physical 1 1 1 PCA
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI physical 1 1 1 PCA
YOP1 YPR028W Reticulon-interacting protein physical 1 1 1 PCA
SPC1 YJR010C-A Subunit of the signal peptidase complex (SPC) physical 1 1 1 PCA
TPO1 YLL028W Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
YPL264C YPL264C Endoplasmic reticulum protein of unknown function physical 1 1 1 PCA
RPS17B YDR447C Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Negative Genetic
MMT1 YMR177W Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Dosage Rescue
MMT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Dosage Rescue
HEM2 YGL040C Aminolevulinate dehydratase genetic 1 1 1 Synthetic Rescue
HEM4 YOR278W Uroporphyrinogen III synthase genetic 1 1 1 Synthetic Rescue
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Negative Genetic
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 1 1 1 Negative Genetic
RPL35A YDL191W Ribosomal 60S subunit protein L35A genetic 1 1 1 Negative Genetic
IPT1 YDR072C Inositolphosphotransferase genetic 1 1 1 Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Positive Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Negative Genetic
YDR248C YDR248C Putative gluconokinase genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
WWM1 YFL010C WW domain containing protein of unknown function genetic 1 1 1 Negative Genetic
ROG1 YGL144C Lipase with specificity for monoacylglycerol genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Negative Genetic
HEL1 YKR017C RING finger ubiquitin ligase (E3) genetic 1 1 1 Negative Genetic
FMP46 YKR049C Putative redox protein containing a thioredoxin fold genetic 1 1 1 Negative Genetic
MSC3 YLR219W Protein of unknown function genetic 1 1 1 Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Positive Genetic
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Negative Genetic
PRM6 YML047C Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Negative Genetic
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 1 1 1 Negative Genetic
MAM3 YOL060C Protein involved in magnesium homeostasis genetic 1 1 1 Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 1 1 1 Negative Genetic
SFG1 YOR315W Nuclear protein putative transcription factor genetic 1 1 1 Negative Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Negative Genetic
YPR089W YPR089W Protein of unknown function genetic 1 1 1 Negative Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus genetic 1 1 1 Synthetic Growth Defect
SHM1 YBR263W Mitochondrial serine hydroxymethyltransferase genetic 1 1 1 Positive Genetic
SAM1 YLR180W S-adenosylmethionine synthetase genetic 1 1 1 Positive Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Positive Genetic
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) genetic 1 1 1 Positive Genetic
FBP26 YJL155C Fructose-2,6-bisphosphatase, required for glucose metabolism genetic 1 1 1 Positive Genetic
MET12 YPL023C Protein with MTHFR activity in vitro genetic 1 1 1 Positive Genetic
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Positive Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Positive Genetic
NDI1 YML120C NADH:ubiquinone oxidoreductase genetic 1 1 1 Negative Genetic
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Positive Genetic
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease genetic 1 1 1 Positive Genetic
GAL7 YBR018C Galactose-1-phosphate uridyl transferase genetic 1 1 1 Negative Genetic
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 1 1 1 Positive Genetic
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Positive Genetic
PCK1 YKR097W Phosphoenolpyruvate carboxykinase genetic 1 1 1 Negative Genetic
PCD1 YLR151C 8-oxo-dGTP diphosphatase genetic 1 1 1 Negative Genetic
POX1 YGL205W Fatty-acyl coenzyme A oxidase genetic 1 1 1 Negative Genetic
IDP3 YNL009W Peroxisomal NADP-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
UGA4 YDL210W GABA (gamma-aminobutyrate) permease genetic 1 1 1 Positive Genetic
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
VMA11 YPL234C Vacuolar ATPase V0 domain subunit c' genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Positive Genetic
GEA1 YJR031C Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) genetic 1 1 1 Negative Genetic
SRO77 YBL106C Protein with roles in exocytosis and cation homeostasis genetic 1 1 1 Negative Genetic
MYO3 YKL129C One of two type I myosins genetic 1 1 1 Negative Genetic
SRF1 YDL133W Regulator of phospholipase D (Spo14p) genetic 1 1 1 Negative Genetic
SPO14 YKR031C Phospholipase D genetic 1 1 1 Negative Genetic
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 1 1 1 Negative Genetic
MTC4 YBR255W Protein of unknown function genetic 1 1 1 Negative Genetic
GEA2 YEL022W Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Positive Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Negative Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
SUR7 YML052W Plasma membrane protein, component of eisosomes genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
LCB5 YLR260W Minor sphingoid long-chain base kinase genetic 1 1 1 Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Negative Genetic
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Negative Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Negative Genetic
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Positive Genetic
YPT31 YER031C Rab family GTPase genetic 1 1 1 Negative Genetic
TVP18 YMR071C Integral membrane protein genetic 1 1 1 Negative Genetic
SMY1 YKL079W Kinesin-like myosin passenger-protein genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Positive Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Positive Genetic
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
PRP6 YBR055C Splicing factor genetic 1 1 1 Negative Genetic
FAD1 YDL045C Flavin adenine dinucleotide (FAD) synthetase genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
GDI1 YER136W GDP dissociation inhibitor genetic 1 1 1 Negative Genetic
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 1 1 1 Negative Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Negative Genetic
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase genetic 1 1 1 Negative Genetic
RSC4 YKR008W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
PMS1 YNL082W ATP-binding protein required for mismatch repair genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
YCR090C YCR090C Putative protein of unknown function genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
MAL12 YGR292W Maltase (alpha-D-glucosidase) genetic 1 1 1 Negative Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
IRS4 YKR019C EH domain-containing protein genetic 1 1 1 Negative Genetic
SHB17 YKR043C Sedoheptulose bisphosphatase involved in riboneogenesis genetic 1 1 1 Negative Genetic
RPS1B YML063W Ribosomal protein of the small (40S) subunit genetic 1 1 1 Negative Genetic
STB4 YMR019W Putative transcription factor genetic 1 1 1 Negative Genetic
PAI3 YMR174C Cytoplasmic proteinase A (Pep4p) inhibitor genetic 1 1 1 Negative Genetic
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Negative Genetic
TDA1 YMR291W Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Negative Genetic
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
YNL134C YNL134C NADH-dependent aldehyde reductase genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 1 1 1 Negative Genetic
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
CQD1 YPL109C UbiB family mitochondrial protein genetic 1 1 1 Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
ALG1 YBR110W Mannosyltransferase physical 1 1 1 PCA
ERG2 YMR202W C-8 sterol isomerase physical 1 1 1 PCA
BAP3 YDR046C Amino acid permease physical 1 1 1 PCA
CUE1 YMR264W Ubiquitin-binding protein physical 1 1 1 PCA
COQ10 YOL008W Coenzyme Q (ubiquinone) binding protein genetic 1 1 1 Negative Genetic
ALD6 YPL061W Cytosolic aldehyde dehydrogenase genetic 1 1 1 Positive Genetic
COS8 YHL048W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
DCW1 YKL046C Putative mannosidase genetic 1 1 1 Negative Genetic
ATG15 YCR068W Phospholipase genetic 1 1 1 Negative Genetic
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 1 1 1 Negative Genetic
CHO1 YER026C Phosphatidylserine synthase physical 1 1 1 PCA
ELO1 YJL196C Elongase I, medium-chain acyl elongase genetic 1 1 1 Negative Genetic
COX8 YLR395C Subunit VIII of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease physical 1 1 1 PCA
ERD2 YBL040C HDEL receptor physical 1 1 1 PCA
AQY1 YPR192W Spore-specific water channel physical 1 1 1 PCA
DGK1 YOR311C Diacylglycerol kinase genetic 1 1 1 Negative Genetic
CDA2 YLR308W Chitin deacetylase genetic 1 1 1 Negative Genetic