ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
7 |
3 |
7 |
Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
7 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
6 |
3 |
5 |
Phenotypic Suppression, Positive Genetic, Phenotypic Suppression, Phenotypic Enhancement, Positive Genetic, Positive Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
6 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
6 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
6 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
5 |
3 |
5 |
Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
INP51 |
YIL002C |
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
genetic |
5 |
2 |
5 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
5 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
5 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ARV1 |
YLR242C |
Cortical ER protein |
genetic |
5 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
YPT31 |
YER031C |
Rab family GTPase |
genetic |
5 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ERG5 |
YMR015C |
C-22 sterol desaturase |
genetic |
5 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic, Positive Genetic |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
AGE2 |
YIL044C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
OLE1 |
YGL055W |
Delta(9) fatty acid desaturase |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ARO7 |
YPR060C |
Chorismate mutase |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic |
CMD1 |
YBR109C |
Calmodulin |
genetic |
5 |
2 |
3 |
Negative Genetic, Positive Genetic, Positive Genetic, Negative Genetic, Positive Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
5 |
2 |
3 |
Negative Genetic, Positive Genetic, Positive Genetic, Negative Genetic, Positive Genetic |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Negative Genetic |
ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
4 |
3 |
4 |
Synthetic Rescue, Synthetic Growth Defect, Positive Genetic, Positive Genetic |
VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
4 |
2 |
4 |
Negative Genetic, Positive Genetic, Negative Genetic, Negative Genetic |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
4 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
APL2 |
YKL135C |
Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
4 |
1 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TVP18 |
YMR071C |
Integral membrane protein |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
4 |
1 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
4 |
3 |
3 |
Phenotypic Suppression, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Negative Genetic |
LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
4 |
2 |
3 |
Phenotypic Enhancement, Positive Genetic, Positive Genetic, Positive Genetic |
BRR6 |
YGL247W |
Essential nuclear envelope integral membrane protein |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
4 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
APL4 |
YPR029C |
Gamma-adaptin |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TRP2 |
YER090W |
Anthranilate synthase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
THI3 |
YDL080C |
Regulatory protein that binds Pdc2p and Thi2p transcription factors |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TKL1 |
YPR074C |
Transketolase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SWH1 |
YAR042W |
Protein similar to mammalian oxysterol-binding protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MTC4 |
YBR255W |
Protein of unknown function |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SUR7 |
YML052W |
Plasma membrane protein, component of eisosomes |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
FRQ1 |
YDR373W |
N-myristoylated calcium-binding protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PDR1 |
YGL013C |
Transcription factor that regulates the pleiotropic drug response |
genetic |
3 |
3 |
3 |
Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Suppression |
SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
3 |
3 |
3 |
Positive Genetic, Synthetic Rescue, Negative Genetic |
ELO3 |
YLR372W |
Elongase |
genetic |
3 |
2 |
3 |
Positive Genetic, Negative Genetic, Negative Genetic |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Rescue, Negative Genetic |
KRE1 |
YNL322C |
Cell wall glycoprotein involved in beta-glucan assembly |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Negative Genetic, Negative Genetic |
SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Negative Genetic, Negative Genetic |
PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
genetic |
3 |
2 |
3 |
Positive Genetic, Negative Genetic, Negative Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
3 |
2 |
3 |
Negative Genetic, Positive Genetic, Positive Genetic |
ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ABD1 |
YBR236C |
Methyltransferase |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ADO1 |
YJR105W |
Adenosine kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
CDC19 |
YAL038W |
Pyruvate kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
SCO1 |
YBR037C |
Copper-binding protein of mitochondrial inner membrane |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
VHC1 |
YBR235W |
Vacuolar membrane cation-chloride cotransporter (CCC) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
YBR238C |
YBR238C |
Mitochondrial membrane protein |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RAD57 |
YDR004W |
Protein that stimulates strand exchange |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
IRC3 |
YDR332W |
Double-stranded DNA-dependent helicase of the DExH/D-box family |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SLO1 |
YER180C-A |
Protein interacting with Arl3p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
UFD1 |
YGR048W |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SHY1 |
YGR112W |
Mitochondrial inner membrane protein required for complex IV assembly |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
HTD2 |
YHR067W |
Mitochondrial 3-hydroxyacyl-thioester dehydratase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SET4 |
YJL105W |
Chromatin-associated protein involved in control of stress response |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
NFU1 |
YKL040C |
Protein involved in Fe-S cluster transfer to mitochondrial clients |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SRP40 |
YKR092C |
Nucleolar serine-rich protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
HLJ1 |
YMR161W |
Co-chaperone for Hsp40p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ESC1 |
YMR219W |
Protein involved in telomeric silencing |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
GCY1 |
YOR120W |
Glycerol dehydrogenase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
PDX3 |
YBR035C |
Pyridoxine (pyridoxamine) phosphate oxidase |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
FUM1 |
YPL262W |
Fumarase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
TDA1 |
YMR291W |
Protein kinase of unknown cellular role |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
UPC2 |
YDR213W |
Sterol regulatory element binding protein |
genetic |
3 |
1 |
3 |
Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
3 |
3 |
2 |
Negative Genetic, Phenotypic Suppression, Positive Genetic |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Positive Genetic |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
3 |
2 |
2 |
Positive Genetic, Positive Genetic, Negative Genetic |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
3 |
2 |
2 |
Positive Genetic, Positive Genetic, Negative Genetic |
MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Positive Genetic |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Positive Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
physical |
3 |
1 |
2 |
PCA, PCA, PCA |
DFG5 |
YMR238W |
Putative mannosidase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
AIM29 |
YKR074W |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
GDI1 |
YER136W |
GDP dissociation inhibitor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
NOP7 |
YGR103W |
Component of several different pre-ribosomal particles |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PFY1 |
YOR122C |
Profilin |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MRS6 |
YOR370C |
Rab escort protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TRP4 |
YDR354W |
Anthranilate phosphoribosyl transferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PUF6 |
YDR496C |
Pumilio-homology domain protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MIL1 |
YFL034W |
Predicted lipase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MTC6 |
YHR151C |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
LST4 |
YKL176C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MEH1 |
YKR007W |
Subunit of the EGO/GSE complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TRS33 |
YOR115C |
Core component of TRAPP complexes I, II and IV |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MAY24 |
YPR153W |
Peripheral ER membrane protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
ERG28 |
YER044C |
Endoplasmic reticulum membrane protein |
physical |
2 |
2 |
2 |
Affinity Capture-Western, PCA |
CSH1 |
YBR161W |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
ISC1 |
YER019W |
Inositol phosphosphingolipid phospholipase C |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Lethality |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Growth Defect |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
ALP1 |
YNL270C |
Arginine transporter |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
BCP1 |
YDR361C |
Essential nuclear chaperone for ribosomal protein Rpl23p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AOS1 |
YPR180W |
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
DBP10 |
YDL031W |
Putative ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
COX4 |
YGL187C |
Subunit IV of cytochrome c oxidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DUG1 |
YFR044C |
Cys-Gly metallo-di-peptidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CRZ1 |
YNL027W |
Transcription factor, activates transcription of stress response genes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ATP3 |
YBR039W |
Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CDC53 |
YDL132W |
Cullin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DLD3 |
YEL071W |
2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ATG4 |
YNL223W |
Conserved cysteine protease required for autophagy |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BUD9 |
YGR041W |
Protein involved in bud-site selection |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ATG2 |
YNL242W |
Peripheral membrane protein required for autophagic vesicle formation |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ALY1 |
YKR021W |
Alpha arrestin, substrate of calcineurin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DBP6 |
YNR038W |
Essential protein involved in ribosome biogenesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
APM2 |
YHL019C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COA4 |
YLR218C |
Twin Cx(9)C protein involved in cytochrome c oxidase organization |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BIL1 |
YOR304C-A |
Protein that binds Bud6p and has a role in actin cable assembly |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ACL4 |
YDR161W |
Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CYC3 |
YAL039C |
Cytochrome c heme lyase (holocytochrome c synthase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EEB1 |
YPL095C |
Acyl-coenzymeA:ethanol O-acyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COA1 |
YIL157C |
Mitochondrial inner membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ALG12 |
YNR030W |
Alpha-1,6-mannosyltransferase localized to the ER |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERG7 |
YHR072W |
Lanosterol synthase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MSS2 |
YDL107W |
Peripherally bound inner membrane protein of the mitochondrial matrix |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PEX29 |
YDR479C |
ER-resident protein involved in peroxisomal biogenesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PEX12 |
YMR026C |
C3HC4-type RING-finger peroxin and E3 ubiquitin ligase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YPL150W |
YPL150W |
Protein kinase of unknown cellular role |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
VPS5 |
YOR069W |
Nexin-1 homolog |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PIL1 |
YGR086C |
Eisosome core component |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TGL2 |
YDR058C |
Triacylglycerol lipase that is localized to the mitochondria |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SEC4 |
YFL005W |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TFC1 |
YBR123C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RIB5 |
YBR256C |
Riboflavin synthase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SEC1 |
YDR164C |
Sm-like protein involved in docking and fusion of exocytic vesicles |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PRP3 |
YDR473C |
Splicing factor |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
KRE29 |
YER038C |
Subunit of the SMC5-SMC6 complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ISD11 |
YER048W-A |
Cysteine desulfurase (Nfs1p) activator |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SCC4 |
YER147C |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YPT1 |
YFL038C |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PHS1 |
YJL097W |
Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
GCD14 |
YJL125C |
Subunit of tRNA (1-methyladenosine) methyltransferase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PRP40 |
YKL012W |
U1 snRNP protein involved in splicing |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
LIP1 |
YMR298W |
Ceramide synthase subunit |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
POP1 |
YNL221C |
Subunit of RNase MRP, nuclear RNase P and telomerase complexes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TSC3 |
YBR058C-A |
Protein that stimulates the activity of serine palmitoyltransferase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YBL055C |
YBL055C |
3'-->5' exonuclease and endonuclease with a possible role in apoptosis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PET112 |
YBL080C |
Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MRPS9 |
YBR146W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MRPS5 |
YBR251W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MRPL27 |
YBR282W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RSM24 |
YDR175C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YER079W |
YER079W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ERG4 |
YGL012W |
C-24(28) sterol reductase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
WSC2 |
YNL283C |
Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
FIG4 |
YNL325C |
Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TIM18 |
YOR297C |
Component of the mitochondrial TIM22 complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RSA4 |
YCR072C |
Ribosomal large subunit (60S) assembly factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TSR1 |
YDL060W |
Protein required for processing of 20S pre-rRNA in the cytoplasm |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SCM3 |
YDL139C |
Nonhistone component of centromeric chromatin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HEM12 |
YDR047W |
Uroporphyrinogen decarboxylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HEM1 |
YDR232W |
5-aminolevulinate synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RRP17 |
YDR412W |
5' exoribonuclease required for 5' end processing of pre-60S rRNA |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TFB3 |
YDR460W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPP41 |
YDR464W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC15 |
YGL233W |
Essential 113 kDa subunit of the exocyst complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VHT1 |
YGR065C |
High-affinity plasma membrane H+-biotin (vitamin H) symporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TFG1 |
YGR186W |
TFIIF (Transcription Factor II) largest subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MAS2 |
YHR024C |
Alpha subunit of the mitochondrial processing protease (MPP) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NMD3 |
YHR170W |
Protein involved in nuclear export of the large ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UTP9 |
YHR196W |
Nucleolar protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RIX1 |
YHR197W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TIM54 |
YJL054W |
Component of the mitochondrial TIM22 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PRP21 |
YJL203W |
Subunit of the SF3a splicing factor complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TFA1 |
YKL028W |
TFIIE large subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MPE1 |
YKL059C |
Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LAS1 |
YKR063C |
Endonuclease involved in pre-rRNA processing at both ends of ITS2 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PWP1 |
YLR196W |
Protein with WD-40 repeats involved in rRNA processing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RRN11 |
YML043C |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC65 |
YML105C |
Subunit of the signal recognition particle (SRP) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC59 |
YMR013C |
Dolichol kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TRS130 |
YMR218C |
Component of transport protein particle (TRAPP) complex II |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SGT1 |
YOR057W |
Cochaperone protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RIO1 |
YOR119C |
Serine kinase involved in cell cycle regulation and rDNA integrity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LAS17 |
YOR181W |
Actin assembly factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPB8 |
YOR224C |
RNA polymerase subunit ABC14.5 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HEM4 |
YOR278W |
Uroporphyrinogen III synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NOG1 |
YPL093W |
Putative GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL33A |
YPL143W |
Ribosomal 60S subunit protein L33A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NSL1 |
YPL233W |
Essential component of the MIND kinetochore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC8 |
YPR055W |
Essential 121 kDa subunit of the exocyst complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RFC5 |
YBR087W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OST1 |
YJL002C |
Alpha subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KRE9 |
YJL174W |
Glycoprotein involved in cell wall beta-glucan assembly |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IPA1 |
YJR141W |
Protein implicated in pre-mRNA processing and proteasomal degradation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NOG2 |
YNR053C |
Putative GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RRS1 |
YOR294W |
Essential protein that binds ribosomal protein L11 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SRP54 |
YPR088C |
Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MYO4 |
YAL029C |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YAL064W |
YAL064W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FLO1 |
YAR050W |
Lectin-like protein involved in flocculation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPK3 |
YBR028C |
AGC kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL21A |
YBR191W |
Ribosomal 60S subunit protein L21A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FTH1 |
YBR207W |
Putative high affinity iron transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YBP1 |
YBR216C |
Protein involved in cellular response to oxidative stress |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YBR285W |
YBR285W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRPL32 |
YCR003W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GPM2 |
YDL021W |
Nonfunctional homolog of Gpm1p phosphoglycerate mutase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS29B |
YDL061C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAM1 |
YDL090C |
Beta subunit of the CAAX farnesyltransferase (FTase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRPL11 |
YDL202W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TFB5 |
YDR079C-A |
Component of RNA polymerase II general transcription factor TFIIH |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PET100 |
YDR079W |
Chaperone that facilitates the assembly of cytochrome c oxidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRPL35 |
YDR322W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HXT6 |
YDR343C |
High-affinity glucose transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL12B |
YDR418W |
Ribosomal 60S subunit protein L12B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TCA17 |
YEL048C |
Component of transport protein particle (TRAPP) complex II |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YER010C |
YER010C |
Bifunctional HMG aldolase/oxaloacetate decarboxylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SSA4 |
YER103W |
Heat shock protein that is highly induced upon stress |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL2A |
YFR031C-A |
Ribosomal 60S subunit protein L2A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YFR035C |
YFR035C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRX20 |
YFR045W |
Putative mitochondrial transport protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL24A |
YGL031C |
Ribosomal 60S subunit protein L24A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RMD9 |
YGL107C |
Mitochondrial protein that controls mitochondrial gene expression |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL1B |
YGL135W |
Ribosomal 60S subunit protein L1B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TPN1 |
YGL186C |
Plasma membrane pyridoxine (vitamin B6) transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YGL188C-A |
YGL188C-A |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
POX1 |
YGL205W |
Fatty-acyl coenzyme A oxidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MTL1 |
YGR023W |
Putative plasma membrane sensor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IMO32 |
YGR031W |
Conserved mitochondrial protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SCM4 |
YGR049W |
Mitochondrial outer membrane protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LST7 |
YGR057C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PDC6 |
YGR087C |
Minor isoform of pyruvate decarboxylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MDR1 |
YGR100W |
Cytoplasmic GTPase-activating protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SYF2 |
YGR129W |
Member of the NineTeen Complex (NTC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FYV8 |
YGR196C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TDA3 |
YHR009C |
Putative oxidoreductase involved in late endosome to Golgi transport |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPS100 |
YHR139C |
Protein required for spore wall maturation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LAM1 |
YHR155W |
Putative sterol transfer protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PPX1 |
YHR201C |
Exopolyphosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RCI37 |
YIL077C |
Protein that associates with the large mitoribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KGD1 |
YIL125W |
Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAU14 |
YIL176C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YJL107C |
YJL107C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YJR056C |
YJR056C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RSM26 |
YJR101W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAN3 |
YKL025C |
Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA5 |
YKL080W |
Subunit C of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MTC2 |
YKL098W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRP8 |
YKL142W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GAP1 |
YKR039W |
General amino acid permease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FMP46 |
YKR049C |
Putative redox protein containing a thioredoxin fold |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HBS1 |
YKR084C |
GTPase with similarity to translation release factors |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TVP38 |
YKR088C |
Integral membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LAA2 |
YBL010C |
Clathrin adaptor (adaptin) accessory protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAR32 |
YDL173W |
Low complexity protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
INO2 |
YDR123C |
Transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MKC7 |
YDR144C |
GPI-anchored aspartyl protease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS25A |
YGR027C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YGR201C |
YGR201C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TRR2 |
YHR106W |
Mitochondrial thioredoxin reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SMN1 |
YHR202W |
Putative AMP hydrolase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YIL024C |
YIL024C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TIF2 |
YJL138C |
Translation initiation factor eIF4A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KKQ8 |
YKL168C |
Putative serine/threonine protein kinase with unknown cellular role |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TRP3 |
YKL211C |
Indole-3-glycerol-phosphate synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PEX30 |
YLR324W |
ER-resident protein involved in peroxisomal biogenesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SAS5 |
YOR213C |
Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TPO4 |
YOR273C |
Polyamine transporter of the major facilitator superfamily |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YOR289W |
YOR289W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SNU66 |
YOR308C |
Component of the U4/U6.U5 snRNP complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAD17 |
YOR368W |
Checkpoint protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GPB1 |
YOR371C |
Multistep regulator of cAMP-PKA signaling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OAZ1 |
YPL052W |
Regulator of ornithine decarboxylase Spe1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YDC1 |
YPL087W |
Alkaline dihydroceramidase, involved in sphingolipid metabolism |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPL088W |
YPL088W |
Putative aryl alcohol dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FMP30 |
YPL103C |
Protein with a role in maintaining mitochondrial morphology |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PXA1 |
YPL147W |
Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL7B |
YPL198W |
Ribosomal 60S subunit protein L7B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPL216W |
YPL216W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FMP40 |
YPL222W |
Mitochondrial AMPylator in the pseudokinase selenoprotein-O family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPR078C |
YPR078C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPR089W |
YPR089W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SAM1 |
YLR180W |
S-adenosylmethionine synthetase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YLR456W |
YLR456W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBX4 |
YMR067C |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ICY1 |
YMR195W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PET111 |
YMR257C |
Mitochondrial translational activator specific for the COX2 mRNA |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PRM15 |
YMR278W |
Phosphoribomutase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YNL067W-B |
YNL067W-B |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YNL194C |
YNL194C |
Integral membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RRG9 |
YNL213C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PEX17 |
YNL214W |
Membrane peroxin of the peroxisomal importomer complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
JJJ1 |
YNL227C |
Co-chaperone that stimulates the ATPase activity of Ssa1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SKP2 |
YNL311C |
F-box protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
URK1 |
YNR012W |
Uridine/cytidine kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRPS12 |
YNR036C |
Mitochondrial protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RSM19 |
YNR037C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SIL1 |
YOL031C |
Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SDH5 |
YOL071W |
Protein required for flavinylation of Sdh1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPO21 |
YOL091W |
Component of the meiotic outer plaque of the spindle pole body |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MDH2 |
YOL126C |
Cytoplasmic malate dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YVC1 |
YOR087W |
Vacuolar cation channel |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RCN2 |
YOR220W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RDL2 |
YOR286W |
Protein with rhodanese activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MEK1 |
YOR351C |
Meiosis-specific serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRX11 |
YPL041C |
Protein that associates with mitochondrial ribosome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPL077C |
YPL077C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PEP4 |
YPL154C |
Vacuolar aspartyl protease (proteinase A) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EDC1 |
YGL222C |
RNA-binding protein that activates mRNA decapping directly |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BSC4 |
YNL269W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DIE2 |
YGR227W |
Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COX9 |
YDL067C |
Subunit VIIa of cytochrome c oxidase (Complex IV) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COX20 |
YDR231C |
Mitochondrial inner membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ALG11 |
YNL048W |
Alpha-1,2-mannosyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ENV9 |
YOR246C |
Conserved oxidoreductase involved in lipid droplet morphology |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BUD25 |
YER014C-A |
Protein involved in bud-site selection |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CAX4 |
YGR036C |
Dolichyl pyrophosphate (Dol-P-P) phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BNI1 |
YNL271C |
Formin |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Synthetic Lethality |
LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
ERG27 |
YLR100W |
3-keto sterol reductase |
physical |
2 |
1 |
1 |
PCA, PCA |
MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SWI6 |
YLR182W |
Transcription cofactor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SET4 |
YJL105W |
Chromatin-associated protein involved in control of stress response |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
genetic |
1 |
1 |
1 |
Positive Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADE4 |
YMR300C |
Phosphoribosylpyrophosphate amidotransferase (PRPPAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
1 |
1 |
1 |
Positive Genetic |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG26 |
YGL001C |
C-3 sterol dehydrogenase |
physical |
1 |
1 |
1 |
PCA |
CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Positive Genetic |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
CPR1 |
YDR155C |
Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
AEP2 |
YMR282C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
1 |
1 |
1 |
Positive Genetic |
BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Positive Genetic |
ABP1 |
YCR088W |
Actin-binding protein of the cortical actin cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
AAC3 |
YBR085W |
Mitochondrial inner membrane ADP/ATP translocator |
genetic |
1 |
1 |
1 |
Positive Genetic |
AIM2 |
YAL049C |
Cytoplasmic protein involved in mitochondrial function or organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
CNB1 |
YKL190W |
Calcineurin B |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENV7 |
YPL236C |
Vacuolar membrane protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG11 |
YPR049C |
Adapter protein for pexophagy and the Cvt targeting pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC60 |
YPL160W |
Cytosolic leucyl tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG20 |
YJL167W |
Farnesyl pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CHS1 |
YNL192W |
Chitin synthase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARF2 |
YDL137W |
ADP-ribosylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIO3 |
YNR058W |
7,8-diamino-pelargonic acid aminotransferase (DAPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBP2 |
YHL038C |
Required for splicing of the group I intron bI5 of the COB pre-mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
physical |
1 |
1 |
1 |
PCA |
EFM1 |
YHL039W |
Lysine methyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
1 |
1 |
1 |
Positive Genetic |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENT3 |
YJR125C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM18 |
YHR198C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM7 |
YDR063W |
Protein that interacts with Arp2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC21 |
YOR074C |
Thymidylate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Positive Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCS1 |
YMR038C |
Copper chaperone for superoxide dismutase Sod1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHS3 |
YBR023C |
Chitin synthase III |
genetic |
1 |
1 |
1 |
Positive Genetic |
AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP1 |
YBL099W |
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENV11 |
YGR071C |
Protein proposed to be involved in vacuolar functions |
genetic |
1 |
1 |
1 |
Positive Genetic |
COX14 |
YML129C |
Mitochondrial cytochrome c oxidase (complex IV) assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADI1 |
YMR009W |
Acireductone dioxygenease involved in methionine salvage pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATX1 |
YNL259C |
Cytosolic copper metallochaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
BAP3 |
YDR046C |
Amino acid permease |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASE1 |
YOR058C |
Mitotic spindle midzone-localized microtubule bundling protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
BPH1 |
YCR032W |
Protein homologous to Chediak-Higashi syndrome and Beige proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ10 |
YOL008W |
Coenzyme Q (ubiquinone) binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP12 |
YJL180C |
Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
APS1 |
YLR170C |
Small subunit of the clathrin-associated adaptor complex AP-1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ6 |
YGR255C |
Flavin-dependent monooxygenase involved in ubiquinone biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
EGH1 |
YIR007W |
Steryl-beta-glucosidase with broad specificity for aglycones |
genetic |
1 |
1 |
1 |
Negative Genetic |
ABZ2 |
YMR289W |
Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAB1 |
YDR531W |
Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
AIM11 |
YER093C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ABM1 |
YJR108W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
DLD2 |
YDL178W |
D-2-hydroxyglutarate dehydrogenase, and minor D-lactate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CHS7 |
YHR142W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG24 |
YNL280C |
C-14 sterol reductase |
physical |
1 |
1 |
1 |
PCA |
CYC1 |
YJR048W |
Cytochrome c, isoform 1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG13 |
YGL047W |
Catalytic component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CPD1 |
YGR247W |
Cyclic nucleotide phosphodiesterase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASI2 |
YNL159C |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYC2 |
YOR037W |
Mitochondrial peripheral inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG3 |
YLR056W |
C-5 sterol desaturase |
physical |
1 |
1 |
1 |
PCA |
ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
PCA |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
physical |
1 |
1 |
1 |
PCA |
ERG7 |
YHR072W |
Lanosterol synthase |
physical |
1 |
1 |
1 |
PCA |
ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
physical |
1 |
1 |
1 |
PCA |
TPO1 |
YLL028W |
Polyamine transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
PCA |
SMF3 |
YLR034C |
Putative divalent metal ion transporter involved in iron homeostasis |
physical |
1 |
1 |
1 |
PCA |
IFA38 |
YBR159W |
Microsomal beta-keto-reductase |
physical |
1 |
1 |
1 |
PCA |
SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
physical |
1 |
1 |
1 |
PCA |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HRD3 |
YLR207W |
ER membrane protein that plays a central role in ERAD |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RCY1 |
YJL204C |
F-box protein involved in recycling endocytosed proteins |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PDR3 |
YBL005W |
Transcriptional activator of the pleiotropic drug resistance network |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAP190 |
YKR028W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UFD4 |
YKL010C |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEX1 |
YNL253W |
Protein involved in mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRM1 |
YNL279W |
Pheromone-regulated multispanning membrane protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TRP1 |
YDR007W |
Phosphoribosylanthranilate isomerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HIS3 |
YOR202W |
Imidazoleglycerol-phosphate dehydratase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFA1 |
YDL168W |
Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAL1 |
YDR021W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM11 |
YDR322C-A |
Subunit e of mitochondrial F1F0-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM4 |
YER112W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET122 |
YER153C |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
USE1 |
YGL098W |
Essential SNARE protein localized to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCY1 |
YGR012W |
Putative cysteine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC7 |
YMR022W |
Ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSS11 |
YMR164C |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP2 |
YNR052C |
Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOB1 |
YOR056C |
Protein involved in proteasomal and 40S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAM10 |
YOR068C |
Protein involved in vacuole morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCO89 |
YPL180W |
Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPO19 |
YPL130W |
Meiosis-specific prospore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCR1 |
YPL006W |
Vacuolar membrane protein involved with Npc2p in sterol trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMH18 |
YPR098C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
HTB1 |
YDR224C |
Histone H2B |
genetic |
1 |
1 |
1 |
Positive Genetic |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SUR2 |
YDR297W |
Sphinganine C4-hydroxylase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HKR1 |
YDR420W |
Mucin family member that functions as an osmosensor in the HOG pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIT1 |
YEL065W |
Ferrioxamine B transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GYP5 |
YPL249C |
GTPase-activating protein (GAP) for yeast Rab family members |
genetic |
1 |
1 |
1 |
Negative Genetic |
YEH2 |
YLR020C |
Steryl ester hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GND1 |
YHR183W |
6-phosphogluconate dehydrogenase (decarboxylating) |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Positive Genetic |
HER2 |
YMR293C |
Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA11 |
YPL234C |
Vacuolar ATPase V0 domain subunit c' |
genetic |
1 |
1 |
1 |
Negative Genetic |
YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEL2 |
YGR099W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NCP1 |
YHR042W |
NADP-cytochrome P450 reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YDL109C |
YDL109C |
Putative lipase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPO14 |
YKR031C |
Phospholipase D |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPS7 |
YDR349C |
Putative GPI-anchored aspartic protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
GEA2 |
YEL022W |
Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRE5 |
YOR336W |
Protein required for beta-1,6 glucan biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
KEX2 |
YNL238W |
Kexin, a subtilisin-like protease (proprotein convertase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YUR1 |
YJL139C |
Mannosyltransferase involved in protein N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC21 |
YNL287W |
Gamma subunit of coatomer |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
LPL1 |
YOR059C |
Phospholipase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSC10 |
YBR265W |
3-ketosphinganine reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RSC3 |
YDR303C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
IPT1 |
YDR072C |
Inositolphosphotransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IQG1 |
YPL242C |
Actin filament binding protein that enhances actin ring formation |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
1 |
1 |
1 |
Positive Genetic |
KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
genetic |
1 |
1 |
1 |
Positive Genetic |
PDR16 |
YNL231C |
Phosphatidylinositol transfer protein (PITP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SND1 |
YDR186C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
YSP2 |
YDR326C |
Sterol-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Positive Genetic |
TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
PHO2 |
YDL106C |
Homeobox transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPI1 |
YHR085W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP13 |
YLR222C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPT1 |
YOL102C |
tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIL055C |
YIL055C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEN54 |
YPL083C |
Subunit of the tRNA splicing endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFC2 |
YJR068W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR220C |
YBR220C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSB1 |
YOR188W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSH1 |
YBR283C |
Subunit of the Ssh1 translocon complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET12 |
YPL023C |
Protein with MTHFR activity in vitro |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC6 |
YIL068C |
Essential 88kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAV2 |
YDR202C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR212W-A |
YHR212W-A |
Pseudogenic fragment with similarity to flocculins |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRX21 |
YPR011C |
Mitochondrial transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS18B |
YML026C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NHP2 |
YDL208W |
Protein related to mammalian high mobility group (HMG) proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRS2 |
YOR334W |
Mitochondrial inner membrane Mg(2+) channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL20A |
YMR242C |
Ribosomal 60S subunit protein L20A |
genetic |
1 |
1 |
1 |
Negative Genetic |
FLC2 |
YAL053W |
Putative calcium channel involved in calcium release under hypotonic |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP42 |
YDL111C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR099C |
YMR099C |
Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
genetic |
1 |
1 |
1 |
Negative Genetic |
XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYO3 |
YKL129C |
One of two type I myosins |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDS3 |
YGL197W |
Putative component of the TOR regulatory pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL4B |
YDR012W |
Ribosomal 60S subunit protein L4B |
genetic |
1 |
1 |
1 |
Negative Genetic |
FDH1 |
YOR388C |
NAD(+)-dependent formate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
REV3 |
YPL167C |
Catalytic subunit of DNA polymerase zeta |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIP2 |
YGL208W |
One of three alternate beta subunits of the Snf1 kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP14 |
YDL148C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
THP3 |
YPR045C |
Protein that may have a role in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO80 |
YGL150C |
Nucleosome spacing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS4 |
YML006C |
CAAX box containing protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL13A |
YDL082W |
Ribosomal 60S subunit protein L13A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMR1 |
YGL250W |
Protein required for meiotic recombination and gene conversion |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSO1 |
YPL232W |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMP21 |
YIL154C |
Transcriptional activator involved in maintenance of ion homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ODC1 |
YPL134C |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOG2 |
YOR353C |
Key component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMP41 |
YNL168C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF3 |
YPL011C |
TFIID subunit (47 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOS4 |
YIL112W |
Subunit of the Set3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM31 |
YHR194W |
Mitochondrial protein that may have a role in phospholipid metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKI6 |
YGR195W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCV1 |
YDR019C |
T subunit of the mitochondrial glycine decarboxylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI21 |
YPL258C |
Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMH11 |
YJR085C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC11 |
YOR339C |
Ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
1 |
1 |
1 |
Negative Genetic |
HYR1 |
YIR037W |
Glutathione peroxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
QNS1 |
YHR074W |
Glutamine-dependent NAD(+) synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VRG4 |
YGL225W |
Golgi GDP-mannose transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
VHS3 |
YOR054C |
Negative regulatory subunit of protein phosphatase 1 Ppz1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML037C |
YML037C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS73 |
YGL104C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMD1 |
YER132C |
Protein with an N-terminal kelch-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSM3 |
YBR272C |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML108W |
YML108W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS4A |
YJR145C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLD5 |
YDR489W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP14 |
YKL082C |
Essential protein, constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRE1 |
YPL176C |
Transferrin receptor-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPN2 |
YNL217W |
Zn2+-dependent endopolyphosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP12 |
YPL012W |
Protein required for export of the ribosomal subunits |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE3 |
YJL001W |
Beta 1 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
LIA1 |
YJR070C |
Deoxyhypusine hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP11 |
YKR098C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR017W |
YGR017W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB4 |
YMR019W |
Putative transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RUB1 |
YDR139C |
Ubiquitin-like protein with similarity to mammalian NEDD8 |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBP2 |
YGL060W |
Central kinetochore associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORM1 |
YGR038W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI6 |
YPL214C |
Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL185C |
YGL185C |
Putative protein with sequence similar to hydroxyacid dehydrogenases |
genetic |
1 |
1 |
1 |
Negative Genetic |
STP1 |
YDR463W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD18 |
YCR066W |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIP3 |
YNL044W |
Protein localized to COPII vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISM1 |
YPL040C |
Mitochondrial isoleucyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR415C |
YDR415C |
Putative aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HXT3 |
YDR345C |
Low affinity glucose transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIN10 |
YFR032C-B |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCS3 |
YGL126W |
Protein required for normal ER membrane biosynthesis in response to ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKL063C |
YKL063C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP15 |
YMR093W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUC1 |
YJL208C |
Major mitochondrial nuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNR021W |
YNR021W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSF1 |
YDR013W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAR035C-A |
YAR035C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRPL24 |
YMR193W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL19A |
YBR084C-A |
Ribosomal 60S subunit protein L19A |
genetic |
1 |
1 |
1 |
Positive Genetic |
YTP1 |
YNL237W |
Probable type-III integral membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRP45 |
YDR280W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
NGR1 |
YBR212W |
RNA binding protein that negatively regulates growth rate |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUS1 |
YDL193W |
Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
YMR262W |
YMR262W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG8 |
YMR220W |
Phosphomevalonate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRPL19 |
YNL185C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS9B |
YBR189W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
LDB7 |
YBL006C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
FZO1 |
YBR179C |
Mitofusin, protein involved in mitochondrial outer membrane fusion |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YIL152W |
YIL152W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MVD1 |
YNR043W |
Mevalonate pyrophosphate decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
INN1 |
YNL152W |
Essential protein that associates with contractile actomyosin ring |
genetic |
1 |
1 |
1 |
Positive Genetic |
TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
PTK1 |
YKL198C |
Putative serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
PBN1 |
YCL052C |
Component of glycosylphosphatidylinositol-mannosyltransferase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
genetic |
1 |
1 |
1 |
Positive Genetic |
RBD2 |
YPL246C |
Possible rhomboid protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAL1 |
YPR005C |
Cytoplasmic protein involved in halotolerance |
genetic |
1 |
1 |
1 |
Positive Genetic |
YML053C |
YML053C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
PUP1 |
YOR157C |
Beta 2 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
TFB4 |
YPR056W |
Subunit of TFIIH complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC7 |
YDR170C |
Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPO31 |
YOR116C |
RNA polymerase III largest subunit C160 |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Positive Genetic |
HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAL12 |
YGR292W |
Maltase (alpha-D-glucosidase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
YSF3 |
YNL138W-A |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPO7 |
YAL009W |
Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP28 |
YDR243C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRI1 |
YMR233W |
Non-essential sumoylated protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
LEM3 |
YNL323W |
Membrane protein of the plasma membrane and ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPT15 |
YER148W |
TATA-binding protein (TBP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TOA1 |
YOR194C |
TFIIA large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
PFK27 |
YOL136C |
6-phosphofructo-2-kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
FES1 |
YBR101C |
Hsp70 (Ssa1p) nucleotide exchange factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
YOL036W |
YOL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
URB2 |
YJR041C |
Protein required for normal metabolism of the rRNA primary transcript |
genetic |
1 |
1 |
1 |
Positive Genetic |
IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YNG1 |
YOR064C |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
LUC7 |
YDL087C |
Essential protein associated with the U1 snRNP complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HMF1 |
YER057C |
Member of the p14.5 protein family |
genetic |
1 |
1 |
1 |
Positive Genetic |
PET18 |
YCR020C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MLH1 |
YMR167W |
Protein required for mismatch repair in mitosis and meiosis |
genetic |
1 |
1 |
1 |
Positive Genetic |
LOS1 |
YKL205W |
Nuclear pore protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Positive Genetic |
RHO5 |
YNL180C |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAL11 |
YGR289C |
High-affinity maltose transporter (alpha-glucoside transporter) |
genetic |
1 |
1 |
1 |
Positive Genetic |
OCA4 |
YCR095C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMP3 |
YOR149C |
Alpha 1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
VID24 |
YBR105C |
GID Complex regulatory subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRPL50 |
YNR022C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERR1 |
YOR393W |
Putative phosphopyruvate hydratase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRM6 |
YML047C |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Positive Genetic |
YKR011C |
YKR011C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
UTR4 |
YEL038W |
Protein with sequence similarity to acireductone synthases |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
1 |
1 |
1 |
Positive Genetic |
HFA1 |
YMR207C |
Mitochondrial acetyl-coenzyme A carboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
PEX32 |
YBR168W |
Peroxisomal integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
IMA1 |
YGR287C |
Major isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRPL51 |
YPR100W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL35A |
YDL191W |
Ribosomal 60S subunit protein L35A |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAC2 |
YER007W |
Microtubule effector required for tubulin heterodimer formation |
genetic |
1 |
1 |
1 |
Positive Genetic |
YOR131C |
YOR131C |
Putative haloacid dehalogenase-like hydrolase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRPL36 |
YBR122C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
YNL035C |
YNL035C |
Nuclear protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
REF2 |
YDR195W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
FYV10 |
YIL097W |
Subunit of GID complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GSH2 |
YOL049W |
Glutathione synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRM7 |
YBR061C |
2'-O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSS1 |
YDR086C |
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MCM6 |
YGL201C |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SET5 |
YHR207C |
Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
KIN82 |
YCR091W |
Putative serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MCP1 |
YOR228C |
Mitochondrial protein of unknown function involved in lipid homeostas |
genetic |
1 |
1 |
1 |
Positive Genetic |
HMG1 |
YML075C |
HMG-CoA reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YJR124C |
YJR124C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSL7 |
YBR133C |
Protein arginine N-methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
LDB16 |
YCL005W |
Protein involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCD10 |
YNL062C |
Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPT2 |
YPL148C |
Phosphopantetheine:protein transferase (PPTase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
THI5 |
YFL058W |
Protein involved in synthesis of the thiamine precursor HMP |
genetic |
1 |
1 |
1 |
Positive Genetic |
GRE1 |
YPL223C |
Hydrophilin essential in desiccation-rehydration process |
genetic |
1 |
1 |
1 |
Positive Genetic |
STR2 |
YJR130C |
Cystathionine gamma-synthase, converts cysteine into cystathionine |
genetic |
1 |
1 |
1 |
Positive Genetic |
MGR1 |
YCL044C |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
OCA2 |
YNL056W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SHG1 |
YBR258C |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD34 |
YDR314C |
Protein involved in nucleotide excision repair (NER) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAK5 |
YBR142W |
Essential nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
PCL10 |
YGL134W |
Pho85p cyclin |
genetic |
1 |
1 |
1 |
Positive Genetic |
RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
SED4 |
YCR067C |
Integral ER membrane protein that stimulates Sar1p GTPase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPP2A |
YOL039W |
Ribosomal protein P2 alpha |
genetic |
1 |
1 |
1 |
Positive Genetic |
KRE2 |
YDR483W |
Alpha1,2-mannosyltransferase of the Golgi |
genetic |
1 |
1 |
1 |
Positive Genetic |
PHM7 |
YOL084W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
TUB3 |
YML124C |
Alpha-tubulin |
genetic |
1 |
1 |
1 |
Positive Genetic |
SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
genetic |
1 |
1 |
1 |
Positive Genetic |
UTR1 |
YJR049C |
ATP-NADH kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MTC3 |
YGL226W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
TFC3 |
YAL001C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SIP5 |
YMR140W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
GFD2 |
YCL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
UPS3 |
YDR185C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MGA1 |
YGR249W |
Protein similar to heat shock transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
PEF1 |
YGR058W |
Penta-EF-hand protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MBA1 |
YBR185C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD14 |
YMR201C |
Subunit of Nucleotide Excision Repair Factor 1 (NEF1) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TED1 |
YIL039W |
GPI-glycan remodelase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SIP3 |
YNL257C |
Putative sterol transfer protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
BIG1 |
YHR101C |
Integral membrane protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDS1 |
YBR029C |
Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALG9 |
YNL219C |
Mannosyltransferase, involved in N-linked glycosylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATG41 |
YPL250C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELO1 |
YJL196C |
Elongase I, medium-chain acyl elongase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRT10 |
YOL063C |
Protein required for the degradation of mutant 25S rRNAs |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMI7 |
YIL002W-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
CBP4 |
YGR174C |
Mitochondrial protein required for assembly of cytochrome bc1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM9 |
YKR004C |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
ECM4 |
YKR076W |
S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) |
genetic |
1 |
1 |
1 |
Positive Genetic |
DLT1 |
YMR126C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CNE1 |
YAL058W |
Calnexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM24 |
YJR080C |
Protein with a role in determining mitochondrial architecture |
genetic |
1 |
1 |
1 |
Positive Genetic |
DPI35 |
YMR130W |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBR1 |
YKL149C |
RNA lariat debranching enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |