SEC65 |
YML105C |
Subunit of the signal recognition particle (SRP) |
physical |
5 |
2 |
4 |
Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS |
SRP14 |
YDL092W |
Signal recognition particle (SRP) subunit |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SEC65 |
YML105C |
Subunit of the signal recognition particle (SRP) |
genetic |
3 |
2 |
3 |
Dosage Rescue, Dosage Rescue, Negative Genetic |
SRP21 |
YKL122C |
Subunit of the signal recognition particle (SRP) |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SRP68 |
YPL243W |
Core component of the signal recognition particle (SRP) complex |
physical |
3 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SRP72 |
YPL210C |
Core component of the signal recognition particle (SRP) |
physical |
3 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex |
RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
LHP1 |
YDL051W |
RNA binding protein required for maturation of tRNA and U6 snRNA |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
physical |
2 |
2 |
1 |
Co-fractionation, Affinity Capture-Western |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
physical |
2 |
1 |
1 |
Reconstituted Complex, Reconstituted Complex |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CAD1 |
YDR423C |
AP-1-like basic leucine zipper (bZIP) transcriptional activator |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
physical |
1 |
1 |
1 |
Co-purification |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSF2 |
YJL072C |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
physical |
1 |
1 |
1 |
Co-purification |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Co-purification |
NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
physical |
1 |
1 |
1 |
Co-purification |
MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
physical |
1 |
1 |
1 |
Co-purification |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Co-purification |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
physical |
1 |
1 |
1 |
Co-purification |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
physical |
1 |
1 |
1 |
Co-purification |
ENO1 |
YGR254W |
Enolase I, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Co-purification |
ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTO1 |
YCR015C |
Protein required for cold tolerance |
physical |
1 |
1 |
1 |
Co-purification |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
physical |
1 |
1 |
1 |
Co-purification |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Co-purification |
MRPL25 |
YGR076C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL28 |
YDR462W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Negative Genetic |
IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPM1 |
YKL152C |
Tetrameric phosphoglycerate mutase |
physical |
1 |
1 |
1 |
Co-purification |
NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Co-purification |
RET3 |
YPL010W |
Zeta subunit of the coatomer complex (COPI) |
physical |
1 |
1 |
1 |
Co-purification |
MSL1 |
YIR009W |
U2B component of U2 snRNP |
physical |
1 |
1 |
1 |
Co-purification |
PRP42 |
YDR235W |
U1 snRNP protein involved in splicing |
physical |
1 |
1 |
1 |
Co-purification |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YTM1 |
YOR272W |
Ribosomal assembly factor and 66S pre-ribosomal particle constituent |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YKU80 |
YMR106C |
Subunit of telomeric Ku complex (Yku70p-Yku80p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YKL070W |
YKL070W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
YJR027W |
YJR027W |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Co-purification |
YEL076C |
YEL076C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
YHL049C |
YHL049C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
YBL081W |
YBL081W |
Non-essential protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
YBR225W |
YBR225W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
YDR124W |
YDR124W |
Mitochondrial protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
YER137C |
YER137C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
YER187W |
YER187W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
THI5 |
YFL058W |
Protein involved in synthesis of the thiamine precursor HMP |
physical |
1 |
1 |
1 |
Co-purification |
STR3 |
YGL184C |
Peroxisomal cystathionine beta-lyase |
physical |
1 |
1 |
1 |
Co-purification |
YHR210C |
YHR210C |
Putative aldose 1-epimerase superfamily protein |
physical |
1 |
1 |
1 |
Co-purification |
YML002W |
YML002W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
YNL193W |
YNL193W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
YPL113C |
YPL113C |
Glyoxylate reductase |
physical |
1 |
1 |
1 |
Co-purification |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
physical |
1 |
1 |
1 |
Co-purification |
TKL2 |
YBR117C |
Transketolase |
physical |
1 |
1 |
1 |
Co-purification |
UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
physical |
1 |
1 |
1 |
Co-purification |
TDP1 |
YBR223C |
Tyrosyl-DNA phosphodiesterase I |
physical |
1 |
1 |
1 |
Co-purification |
THI2 |
YBR240C |
Transcriptional activator of thiamine biosynthetic genes |
physical |
1 |
1 |
1 |
Co-purification |
THI3 |
YDL080C |
Regulatory protein that binds Pdc2p and Thi2p transcription factors |
physical |
1 |
1 |
1 |
Co-purification |
ZPR1 |
YGR211W |
Essential protein with two zinc fingers |
physical |
1 |
1 |
1 |
Co-purification |
TAD2 |
YJL035C |
Subunit of tRNA-specific adenosine-34 deaminase |
physical |
1 |
1 |
1 |
Co-purification |
ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
physical |
1 |
1 |
1 |
Co-purification |
UTP18 |
YJL069C |
Small-subunit processome protein involved in pre-18S rRNA maturation |
physical |
1 |
1 |
1 |
Co-purification |
TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
physical |
1 |
1 |
1 |
Co-purification |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
physical |
1 |
1 |
1 |
Co-purification |
YBL005W-A |
YBL005W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Co-purification |
YGR109W-A |
YGR109W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Co-purification |
TIM12 |
YBR091C |
Essential protein of the inner mitochondrial membrane |
physical |
1 |
1 |
1 |
Co-purification |
YMC2 |
YBR104W |
Putative mitochondrial inner membrane transporter |
physical |
1 |
1 |
1 |
Co-purification |
TAO3 |
YIL129C |
Component of the RAM signaling network |
physical |
1 |
1 |
1 |
Co-purification |
TES1 |
YJR019C |
Peroxisomal acyl-CoA thioesterase |
physical |
1 |
1 |
1 |
Co-purification |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
physical |
1 |
1 |
1 |
Co-purification |
YDR476C |
YDR476C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YBR221W-A |
YBR221W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TFC1 |
YBR123C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Negative Genetic |
UFD1 |
YGR048W |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR071W |
YBR071W |
Protein of unknown function found in the cytoplasm and bud neck |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSH1 |
YBR283C |
Subunit of the Ssh1 translocon complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
genetic |
1 |
1 |
1 |
Negative Genetic |
THO1 |
YER063W |
Conserved nuclear RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIL134C-A |
YIL134C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VBA5 |
YKR105C |
Plasma membrane protein of the Major Facilitator Superfamily (MFS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI7 |
YLR237W |
Plasma membrane transporter responsible for the uptake of thiamine |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML096W |
YML096W |
Putative protein with similarity to asparagine synthetases |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
physical |
1 |
1 |
1 |
Co-purification |
MNL1 |
YHR204W |
Alpha-1,2-specific exomannosidase of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP2 |
YJR121W |
Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
physical |
1 |
1 |
1 |
Co-purification |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Dosage Rescue |
IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NMD5 |
YJR132W |
Karyopherin |
physical |
1 |
1 |
1 |
Co-purification |
MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
physical |
1 |
1 |
1 |
Co-purification |
GSP2 |
YOR185C |
GTP binding protein (mammalian Ranp homolog) |
physical |
1 |
1 |
1 |
Co-purification |
GSP1 |
YLR293C |
Ran GTPase |
physical |
1 |
1 |
1 |
Co-purification |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
physical |
1 |
1 |
1 |
Co-purification |
AGX1 |
YFL030W |
Alanine:glyoxylate aminotransferase (AGT) |
physical |
1 |
1 |
1 |
Co-purification |
HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CYC8 |
YBR112C |
General transcriptional co-repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
COS111 |
YBR203W |
Protein required for antifungal drug ciclopirox olamine resistance |
physical |
1 |
1 |
1 |
Co-purification |
CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
physical |
1 |
1 |
1 |
Co-purification |
MOH1 |
YBL049W |
Protein of unknown function, essential for stationary phase survival |
physical |
1 |
1 |
1 |
Co-purification |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Two-hybrid |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAF4 |
YKR036C |
WD40 repeat-containing protein associated with the CCR4-NOT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GAL3 |
YDR009W |
Transcriptional regulator |
physical |
1 |
1 |
1 |
Co-purification |
MAP2 |
YBL091C |
Methionine aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDH2 |
YOL126C |
Cytoplasmic malate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GID10 |
YGR066C |
Recognition component (N-recognin) of the Pro/N-degron pathway |
physical |
1 |
1 |
1 |
Co-purification |
NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GDH2 |
YDL215C |
NAD(+)-dependent glutamate dehydrogenase |
physical |
1 |
1 |
1 |
Co-purification |
ATP7 |
YKL016C |
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAD1 |
YDR016C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Co-purification |
DAD2 |
YKR083C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX29 |
YDR479C |
ER-resident protein involved in peroxisomal biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADE2 |
YOR128C |
Phosphoribosylaminoimidazole carboxylase |
physical |
1 |
1 |
1 |
Two-hybrid |
CDD1 |
YLR245C |
Cytidine deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIT2 |
YCR005C |
Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle |
physical |
1 |
1 |
1 |
Co-purification |
INO2 |
YDR123C |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
physical |
1 |
1 |
1 |
Co-purification |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
physical |
1 |
1 |
1 |
Co-purification |
MSH5 |
YDL154W |
Protein of the MutS family |
physical |
1 |
1 |
1 |
Co-purification |
MRX16 |
YDR132C |
Protein that associates with the large mitoribosomal subunit |
physical |
1 |
1 |
1 |
Co-purification |
CHA4 |
YLR098C |
DNA binding transcriptional activator |
physical |
1 |
1 |
1 |
Co-purification |
SHU1 |
YHL006C |
Component of Shu complex (aka PCSS complex) |
physical |
1 |
1 |
1 |
Co-purification |
FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
IBD2 |
YNL164C |
Component of the BUB2-dependent spindle checkpoint pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
physical |
1 |
1 |
1 |
Co-purification |
CEP3 |
YMR168C |
Essential kinetochore protein |
physical |
1 |
1 |
1 |
Co-purification |
GIP3 |
YPL137C |
Cytoplasmic protein that regulates protein phosphatase 1 Glc7p |
physical |
1 |
1 |
1 |
Co-purification |
HTL1 |
YCR020W-B |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMC2 |
YFR031C |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGT1 |
YKL038W |
Glucose-responsive transcription factor |
physical |
1 |
1 |
1 |
Co-purification |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
physical |
1 |
1 |
1 |
Co-purification |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
physical |
1 |
1 |
1 |
Co-purification |
SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
physical |
1 |
1 |
1 |
Co-purification |
SEC22 |
YLR268W |
R-SNARE protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
CIN1 |
YOR349W |
Tubulin folding factor D involved in beta-tubulin (Tub2p) folding |
physical |
1 |
1 |
1 |
Co-purification |
SCC2 |
YDR180W |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
physical |
1 |
1 |
1 |
Co-purification |
HAP1 |
YLR256W |
Zinc finger transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET494 |
YNR045W |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMR2 |
YOR093C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
SPC25 |
YER018C |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Co-purification |
PEX30 |
YLR324W |
ER-resident protein involved in peroxisomal biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PEX30 |
YLR324W |
ER-resident protein involved in peroxisomal biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL1A |
YPL220W |
Ribosomal 60S subunit protein L1A |
physical |
1 |
1 |
1 |
Co-purification |
REC8 |
YPR007C |
Meiosis-specific component of the sister chromatid cohesion complex |
physical |
1 |
1 |
1 |
Co-purification |
SHG1 |
YBR258C |
Subunit of the COMPASS (Set1C) complex |
physical |
1 |
1 |
1 |
Co-purification |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
physical |
1 |
1 |
1 |
Co-purification |
ATG10 |
YLL042C |
Conserved E2-like conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
physical |
1 |
1 |
1 |
Co-purification |
SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
physical |
1 |
1 |
1 |
Co-purification |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Co-purification |
RPL29 |
YFR032C-A |
Ribosomal 60S subunit protein L29 |
physical |
1 |
1 |
1 |
Co-purification |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG5 |
YMR015C |
C-22 sterol desaturase |
physical |
1 |
1 |
1 |
Co-purification |
CRG1 |
YHR209W |
S-AdoMet-dependent methyltransferase involved in lipid homeostasis |
physical |
1 |
1 |
1 |
Co-purification |
MDM1 |
YML104C |
PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROG3 |
YFR022W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
physical |
1 |
1 |
1 |
Co-purification |
HUL4 |
YJR036C |
Protein with similarity to hect domain E3 ubiquitin-protein ligases |
physical |
1 |
1 |
1 |
Co-purification |
PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET17 |
YLR303W |
O-acetyl homoserine-O-acetyl serine sulfhydrylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
BPL1 |
YDL141W |
Biotin:apoprotein ligase |
physical |
1 |
1 |
1 |
Co-purification |
NSI1 |
YDR026C |
RNA polymerase I termination factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ICL1 |
YER065C |
Isocitrate lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GUK1 |
YDR454C |
Guanylate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSS1 |
YMR023C |
Mitochondrial protein |
physical |
1 |
1 |
1 |
Co-purification |
NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSM24 |
YDR175C |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Co-purification |
ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Co-purification |
PMU1 |
YKL128C |
Putative phosphomutase |
physical |
1 |
1 |
1 |
Co-purification |
GCV3 |
YAL044C |
H subunit of the mitochondrial glycine decarboxylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAD1 |
YDR538W |
Phenylacrylic acid decarboxylase |
physical |
1 |
1 |
1 |
Co-purification |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PGS1 |
YCL004W |
Phosphatidylglycerolphosphate synthase |
physical |
1 |
1 |
1 |
Co-purification |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
physical |
1 |
1 |
1 |
Co-purification |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS14B |
YJL191W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Co-purification |
SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
physical |
1 |
1 |
1 |
Co-purification |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
physical |
1 |
1 |
1 |
Co-purification |
PTP1 |
YDL230W |
Phosphotyrosine-specific protein phosphatase |
physical |
1 |
1 |
1 |
Co-purification |
RDR1 |
YOR380W |
Transcriptional repressor involved in regulating multidrug resistance |
physical |
1 |
1 |
1 |
Co-purification |
DAP2 |
YHR028C |
Dipeptidyl aminopeptidase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGM1 |
YMR182C |
Putative zinc finger DNA binding transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGO1 |
YOR073W |
Component of the spindle checkpoint |
physical |
1 |
1 |
1 |
Co-purification |
RPS27B |
YHR021C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Co-purification |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
QNS1 |
YHR074W |
Glutamine-dependent NAD(+) synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHD1 |
YKL043W |
Transcriptional activator that enhances pseudohyphal growth |
physical |
1 |
1 |
1 |
Co-purification |
ENA1 |
YDR040C |
P-type ATPase sodium pump |
genetic |
1 |
1 |
1 |
Negative Genetic |
POM34 |
YLR018C |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Co-purification |
BSC1 |
YDL037C |
Protein of unconfirmed function |
physical |
1 |
1 |
1 |
Co-purification |
MAL13 |
YGR288W |
MAL-activator protein |
physical |
1 |
1 |
1 |
Co-purification |
CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
physical |
1 |
1 |
1 |
Co-purification |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IML2 |
YJL082W |
Protein required for clearance of inclusion bodies |
genetic |
1 |
1 |
1 |
Negative Genetic |
MHO1 |
YJR008W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
SED4 |
YCR067C |
Integral ER membrane protein that stimulates Sar1p GTPase activity |
physical |
1 |
1 |
1 |
Co-purification |
GLO1 |
YML004C |
Monomeric glyoxalase I |
physical |
1 |
1 |
1 |
Co-purification |
DPL1 |
YDR294C |
Dihydrosphingosine phosphate lyase |
physical |
1 |
1 |
1 |
Co-purification |
LDO45 |
YMR147W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Co-purification |
NAT4 |
YMR069W |
N alpha-acetyl-transferase |
physical |
1 |
1 |
1 |
Co-purification |
MRX14 |
YDR115W |
Putative mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Co-purification |
LIH1 |
YJR107W |
Putative lipase |
physical |
1 |
1 |
1 |
Co-purification |
MXR2 |
YCL033C |
Methionine-R-sulfoxide reductase |
physical |
1 |
1 |
1 |
Co-purification |
CBP4 |
YGR174C |
Mitochondrial protein required for assembly of cytochrome bc1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
AIM32 |
YML050W |
2Fe-2S mitochondrial protein involved in redox quality control |
physical |
1 |
1 |
1 |
Co-purification |
MAL33 |
YBR297W |
MAL-activator protein |
physical |
1 |
1 |
1 |
Co-purification |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
JHD1 |
YER051W |
JmjC domain family histone demethylase specific for H3-K36 |
physical |
1 |
1 |
1 |
Co-purification |
LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTS2 |
YDR371W |
Putative chitinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBT1 |
YKL208W |
Protein involved in 5' RNA end processing |
physical |
1 |
1 |
1 |
Co-purification |
SFM1 |
YOR021C |
SPOUT methyltransferase |
physical |
1 |
1 |
1 |
Co-purification |
BDS1 |
YOL164W |
Bacterially-derived sulfatase |
physical |
1 |
1 |
1 |
Co-purification |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPM1 |
YDR435C |
Carboxyl methyltransferase |
physical |
1 |
1 |
1 |
Co-purification |
SDH7 |
YDR511W |
Mitochondrial protein involved in assembly of succinate dehydrogenase |
physical |
1 |
1 |
1 |
Co-purification |
RRF1 |
YHR038W |
Mitochondrial ribosome recycling factor |
physical |
1 |
1 |
1 |
Co-purification |
ALP1 |
YNL270C |
Arginine transporter |
physical |
1 |
1 |
1 |
Co-purification |
PPT2 |
YPL148C |
Phosphopantetheine:protein transferase (PPTase) |
genetic |
1 |
1 |
1 |
Negative Genetic |