Standard name Systematic name Name description Description
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER Thiol oxidase required for oxidative protein folding in the ER; essential for maintaining ER redox balance; feedback regulated via reduction and oxidation of regulatory bonds; reduced Pdi1p activates Ero1p by direct reduction of Ero1p regulatory bonds; depletion of thiol substrates and accumulation of oxidized Pdi1p results in inactivation of Ero1p by both Pdi1p-mediated oxidation and autonomous oxidation of Ero1p regulatory bonds; ero1-1 mutation complemented by human ERO1L
Visualize the interactome of ERO1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ERO1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PDI1 YCL043C Protein disulfide isomerase physical 4 3 4 Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ROT2 YBR229C Glucosidase II catalytic subunit genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SSH1 YBR283C Subunit of the Ssh1 translocon complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YBT1 YLL048C Transporter of the ATP-binding cassette (ABC) family genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PHO80 YOL001W Cyclin genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
UBP1 YDL122W Ubiquitin-specific protease genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FMN1 YDR236C Riboflavin kinase, produces riboflavin monophosphate (FMN) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CMD1 YBR109C Calmodulin genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CNE1 YAL058W Calnexin genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
OSM1 YJR051W Fumarate reductase, catalyzes the reduction of fumarate to succinate physical 3 2 1 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
PDI1 YCL043C Protein disulfide isomerase genetic 2 2 2 Synthetic Lethality, Negative Genetic
PBN1 YCL052C Component of glycosylphosphatidylinositol-mannosyltransferase I genetic 2 2 2 Synthetic Lethality, Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 2 1 2 Negative Genetic, Negative Genetic
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex genetic 2 1 2 Negative Genetic, Negative Genetic
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 2 1 2 Negative Genetic, Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 2 1 2 Positive Genetic, Positive Genetic
ERV41 YML067C Protein localized to COPII-coated vesicles physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ERV46 YAL042W Protein localized to COPII-coated vesicles physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SEC13 YLR208W Structural component of 3 complexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
OST1 YJL002C Alpha subunit of the oligosaccharyltransferase complex of the ER lumen physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PWP2 YCR057C Conserved 90S pre-ribosomal component physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LRE1 YCL051W Protein involved in control of cell wall structure and stress response genetic 2 1 2 Negative Genetic, Negative Genetic
SHE10 YGL228W Protein involved in outer spore wall assembly genetic 2 1 2 Negative Genetic, Negative Genetic
YKE4 YIL023C Zinc transporter genetic 2 1 2 Negative Genetic, Negative Genetic
STE24 YJR117W Highly conserved zinc metalloprotease genetic 2 1 2 Negative Genetic, Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 2 1 2 Negative Genetic, Negative Genetic
ZRC1 YMR243C Vacuolar membrane zinc transporter genetic 2 1 2 Negative Genetic, Negative Genetic
HUT1 YPL244C Protein with a role in UDP-galactose transport to the Golgi lumen genetic 2 1 2 Negative Genetic, Negative Genetic
GPI18 YBR004C Functional ortholog of human PIG-V genetic 2 1 2 Negative Genetic, Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
KRE5 YOR336W Protein required for beta-1,6 glucan biosynthesis genetic 2 1 2 Negative Genetic, Negative Genetic
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 2 1 2 Negative Genetic, Negative Genetic
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis genetic 2 1 2 Negative Genetic, Negative Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 2 1 2 Negative Genetic, Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 2 1 2 Negative Genetic, Negative Genetic
SLP1 YOR154W Glycosylated integral ER membrane protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 2 1 2 Negative Genetic, Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 2 1 2 Negative Genetic, Negative Genetic
CNB1 YKL190W Calcineurin B genetic 2 1 2 Negative Genetic, Negative Genetic
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) genetic 2 1 2 Negative Genetic, Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 2 1 2 Negative Genetic, Negative Genetic
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3 genetic 2 1 2 Negative Genetic, Negative Genetic
EMP65 YER140W Integral membrane protein of the ER genetic 2 1 2 Negative Genetic, Negative Genetic
SSS1 YDR086C Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) genetic 2 1 1 Negative Genetic, Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 1 1 Negative Genetic, Negative Genetic
YIP1 YGR172C Integral membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 2 1 1 Negative Genetic, Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 2 1 1 Negative Genetic, Negative Genetic
SPC3 YLR066W Subunit of signal peptidase complex genetic 2 1 1 Negative Genetic, Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 2 1 1 Negative Genetic, Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 2 1 1 Negative Genetic, Negative Genetic
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
BIG1 YHR101C Integral membrane protein of the endoplasmic reticulum genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT6 YGR116W Nucleosome remodeling protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Positive Genetic
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Positive Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly genetic 1 1 1 Negative Genetic
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Positive Genetic
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family genetic 1 1 1 Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Positive Genetic
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Positive Genetic
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
BNI1 YNL271C Formin genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Positive Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
OST1 YJL002C Alpha subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
PWP2 YCR057C Conserved 90S pre-ribosomal component genetic 1 1 1 Negative Genetic
MPD2 YOL088C Member of the protein disulfide isomerase (PDI) family physical 1 1 1 Affinity Capture-Western
PMT1 YDL095W Protein O-mannosyltransferase of the ER membrane physical 1 1 1 Affinity Capture-MS
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane physical 1 1 1 Affinity Capture-MS
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 1 1 1 Positive Genetic
TRX1 YLR043C Cytoplasmic thioredoxin isoenzyme physical 1 1 1 Biochemical Activity
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER physical 1 1 1 Affinity Capture-MS
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 1 1 1 Affinity Capture-MS
OSM1 YJR051W Fumarate reductase, catalyzes the reduction of fumarate to succinate genetic 1 1 1 Negative Genetic
ERV2 YPR037C Flavin-linked sulfhydryl oxidase localized to the ER lumen genetic 1 1 1 Dosage Rescue
LEU2 YCL018W Beta-isopropylmalate dehydrogenase (IMDH) genetic 1 1 1 Synthetic Growth Defect
GID7 YCL039W Subunit of GID Complex that binds directly to central component Vid30p genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
NDE2 YDL085W Mitochondrial external NADH dehydrogenase genetic 1 1 1 Negative Genetic
RPO41 YFL036W Mitochondrial RNA polymerase genetic 1 1 1 Negative Genetic
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
SNO1 YMR095C Protein of unconfirmed function genetic 1 1 1 Negative Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Positive Genetic
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export genetic 1 1 1 Positive Genetic
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Positive Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Positive Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Positive Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Positive Genetic
SOF1 YLL011W Protein required for biogenesis of 40S (small) ribosomal subunit genetic 1 1 1 Positive Genetic
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Positive Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Positive Genetic
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 1 1 1 Positive Genetic
VID24 YBR105C GID Complex regulatory subunit genetic 1 1 1 Positive Genetic
PER1 YCR044C Protein of the endoplasmic reticulum genetic 1 1 1 Positive Genetic
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Positive Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Positive Genetic
RNY1 YPL123C Vacuolar RNase of the T(2) family genetic 1 1 1 Positive Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Positive Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
RIB5 YBR256C Riboflavin synthase genetic 1 1 1 Negative Genetic
FAD1 YDL045C Flavin adenine dinucleotide (FAD) synthetase genetic 1 1 1 Negative Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Negative Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Negative Genetic
UTP7 YER082C Nucleolar protein genetic 1 1 1 Negative Genetic
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Negative Genetic
THS1 YIL078W Threonyl-tRNA synthetase genetic 1 1 1 Negative Genetic
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) genetic 1 1 1 Negative Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
MTR2 YKL186C mRNA transport regulator genetic 1 1 1 Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
KAE1 YKR038C Highly conserved ATPase of HSP70/DnaK family genetic 1 1 1 Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
RIB7 YBR153W Diaminohydroxyphoshoribosylaminopyrimidine deaminase genetic 1 1 1 Negative Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
MAK21 YDR060W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 1 1 1 Negative Genetic
UTP5 YDR398W Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Negative Genetic
NBP35 YGL091C Essential cytoplasmic iron-sulfur cluster binding protein genetic 1 1 1 Negative Genetic
TIM44 YIL022W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
GSP1 YLR293C Ran GTPase genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
SEC62 YPL094C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) genetic 1 1 1 Negative Genetic
NUT2 YPR168W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 1 1 1 Negative Genetic
PGA2 YNL149C Essential protein required for maturation of Gas1p and Pho8p genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Negative Genetic
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p genetic 1 1 1 Negative Genetic
RIB2 YOL066C Bifunctional DRAP deaminase tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
FUN30 YAL019W Snf2p family member with ATP-dependent chromatin remodeling activity genetic 1 1 1 Negative Genetic
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Negative Genetic
RER1 YCL001W Protein involved in retention of membrane proteins genetic 1 1 1 Negative Genetic
FIG2 YCR089W Cell wall adhesin, expressed specifically during mating genetic 1 1 1 Negative Genetic
YCR099C YCR099C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Negative Genetic
RPL35B YDL136W Ribosomal 60S subunit protein L35B genetic 1 1 1 Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
SED1 YDR077W Major stress-induced structural GPI-cell wall glycoprotein genetic 1 1 1 Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Negative Genetic
RMD5 YDR255C Component of GID Complex that confers ubiquitin ligase (U3) activity genetic 1 1 1 Negative Genetic
TMN3 YER113C Protein with a role in cellular adhesion and filamentous growth genetic 1 1 1 Negative Genetic
RTR1 YER139C Dual specificity protein phosphatase genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
FYV8 YGR196C Protein of unknown function genetic 1 1 1 Negative Genetic
YHL017W YHL017W Putative protein of unknown function genetic 1 1 1 Negative Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
HPM1 YIL110W AdoMet-dependent methyltransferase genetic 1 1 1 Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
YUR1 YJL139C Mannosyltransferase involved in protein N-glycosylation genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
PHO90 YJL198W Low-affinity phosphate transporter genetic 1 1 1 Negative Genetic
JJJ3 YJR097W Iron-binding protein genetic 1 1 1 Negative Genetic
RPS30A YLR287C-A Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TSR2 YLR435W Protein with a potential role in pre-rRNA processing genetic 1 1 1 Negative Genetic
OCA2 YNL056W Protein of unknown function genetic 1 1 1 Negative Genetic
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 1 1 1 Negative Genetic
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Negative Genetic
SFG1 YOR315W Nuclear protein putative transcription factor genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
RLM1 YPL089C MADS-box transcription factor genetic 1 1 1 Negative Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
PAU8 YAL068C Protein of unknown function genetic 1 1 1 Negative Genetic
SRO77 YBL106C Protein with roles in exocytosis and cation homeostasis genetic 1 1 1 Negative Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Negative Genetic
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
THI2 YBR240C Transcriptional activator of thiamine biosynthetic genes genetic 1 1 1 Negative Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Negative Genetic
MIC10 YCL057C-A Conserved component of the MICOS complex genetic 1 1 1 Negative Genetic
YDR003W-A YDR003W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RAD61 YDR014W Subunit of a complex that inhibits sister chromatid cohesion genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
YCF1 YDR135C Vacuolar glutathione S-conjugate transporter genetic 1 1 1 Negative Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Negative Genetic
GCN2 YDR283C Protein kinase genetic 1 1 1 Negative Genetic
MGP12 YDR286C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
YDR338C YDR338C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YDR524W-C YDR524W-C Putative protein of unknown function genetic 1 1 1 Negative Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Negative Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
FCY22 YER060W-A Putative purine-cytosine permease genetic 1 1 1 Negative Genetic
ZNF1 YFL052W Zinc cluster transcription factor that regulates respiratory growth genetic 1 1 1 Negative Genetic
LIF1 YGL090W Component of the DNA ligase IV complex genetic 1 1 1 Negative Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Negative Genetic
RPL9A YGL147C Ribosomal 60S subunit protein L9A genetic 1 1 1 Negative Genetic
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins genetic 1 1 1 Negative Genetic
VMA7 YGR020C Subunit F of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PDX1 YGR193C E3-binding protein of the mitochondrial pyruvate dehydrogenase complex genetic 1 1 1 Negative Genetic
YGR204C-A YGR204C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
PAU12 YGR294W Protein of unknown function genetic 1 1 1 Negative Genetic
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein genetic 1 1 1 Negative Genetic
PAU15 YIR041W Protein of unknown function genetic 1 1 1 Negative Genetic
RPL17B YJL177W Ribosomal 60S subunit protein L17B genetic 1 1 1 Negative Genetic
RPS14B YJL191W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
MNS1 YJR131W Alpha-1,2-mannosidase genetic 1 1 1 Negative Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
TGL1 YKL140W Steryl ester hydrolase genetic 1 1 1 Negative Genetic
SRP40 YKR092C Nucleolar serine-rich protein genetic 1 1 1 Negative Genetic
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
RPS28B YLR264W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RIF2 YLR453C Protein that binds to the Rap1p C-terminus genetic 1 1 1 Negative Genetic
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Negative Genetic
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Negative Genetic
LAG2 YOL025W Protein that negatively regulates the SCF E3-ubiquitin ligase genetic 1 1 1 Negative Genetic
YOL038C-A YOL038C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
FDH1 YOR388C NAD(+)-dependent formate dehydrogenase genetic 1 1 1 Negative Genetic
YPL060C-A YPL060C-A TyA Gag protein genetic 1 1 1 Negative Genetic
THI6 YPL214C Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase genetic 1 1 1 Negative Genetic
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Negative Genetic
YPR202W YPR202W Putative protein of unknown function genetic 1 1 1 Negative Genetic
GRX6 YDL010W Cis-Golgi localized monothiol glutaredoxin, binds Fe-S cluster genetic 1 1 1 Synthetic Rescue
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
FLC2 YAL053W Putative calcium channel involved in calcium release under hypotonic genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Positive Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Positive Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 1 1 1 Positive Genetic
SOK1 YDR006C Protein of unknown function genetic 1 1 1 Positive Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Positive Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Positive Genetic
GDI1 YER136W GDP dissociation inhibitor genetic 1 1 1 Positive Genetic
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Positive Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Positive Genetic
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Positive Genetic
PAN2 YGL094C Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex genetic 1 1 1 Positive Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Positive Genetic
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 1 1 1 Positive Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Positive Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Positive Genetic
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Negative Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Positive Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
HSP150 YJL159W O-mannosylated heat shock protein genetic 1 1 1 Positive Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Negative Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Positive Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
GCN3 YKR026C Alpha subunit of translation initiation factor eIF2B genetic 1 1 1 Positive Genetic
SDH2 YLL041C Iron-sulfur protein subunit of succinate dehydrogenase genetic 1 1 1 Positive Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Positive Genetic
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Positive Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 1 1 1 Positive Genetic
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Positive Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 1 1 1 Negative Genetic
SLK19 YOR195W Kinetochore-associated protein genetic 1 1 1 Positive Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 1 1 1 Positive Genetic
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Negative Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Positive Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Positive Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Positive Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Positive Genetic
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
YJR011C YJR011C Putative protein of unknown function genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Positive Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Negative Genetic
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p genetic 1 1 1 Positive Genetic
CSR2 YPR030W Nuclear ubiquitin protein ligase binding protein genetic 1 1 1 Positive Genetic
CDC53 YDL132W Cullin genetic 1 1 1 Negative Genetic
ARP10 YDR106W Component of the dynactin complex genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Positive Genetic
CCE1 YKL011C Mitochondrial cruciform cutting endonuclease genetic 1 1 1 Negative Genetic
CMG1 YLR271W Putative protein of unknown function genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
CLG1 YGL215W Cyclin-like protein that interacts with Pho85p genetic 1 1 1 Negative Genetic
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Positive Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
DFG5 YMR238W Putative mannosidase genetic 1 1 1 Negative Genetic
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 1 1 1 Negative Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Negative Genetic
ATG33 YLR356W Mitochondrial mitophagy-specific protein genetic 1 1 1 Negative Genetic
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Positive Genetic
CWH41 YGL027C Processing alpha glucosidase I genetic 1 1 1 Negative Genetic
DFM1 YDR411C Endoplasmic reticulum (ER) localized protein genetic 1 1 1 Negative Genetic
AGE2 YIL044C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector genetic 1 1 1 Negative Genetic
ALG13 YGL047W Catalytic component of UDP-GlcNAc transferase genetic 1 1 1 Negative Genetic
DFG16 YOR030W Probable multiple transmembrane protein genetic 1 1 1 Negative Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 1 1 1 Negative Genetic
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) genetic 1 1 1 Negative Genetic
DDL1 YOR022C DDHD domain-containing phospholipase A1 genetic 1 1 1 Negative Genetic
AVT5 YBL089W Putative transporter genetic 1 1 1 Negative Genetic
ARN1 YHL040C ARN family transporter for siderophore-iron chelates genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic
ALG8 YOR067C Glucosyl transferase genetic 1 1 1 Negative Genetic
DDI3 YFL061W Cyanamide hydratase that detoxifies cyanamide genetic 1 1 1 Negative Genetic