NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
19 |
5 |
11 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-purification, Co-crystal Structure, Co-crystal Structure, Reconstituted Complex, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure |
NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
15 |
4 |
11 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
physical |
13 |
3 |
11 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
8 |
2 |
6 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SEC13 |
YLR208W |
Structural component of 3 complexes |
physical |
7 |
2 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
physical |
5 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
physical |
5 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
RTC1 |
YOL138C |
Subunit of SEACAT, a subcomplex of the SEA complex |
physical |
5 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
4 |
2 |
4 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence |
IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
SEA4 |
YBL104C |
Subunit of SEACAT, a subcomplex of the SEA complex |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
3 |
3 |
3 |
Affinity Capture-MS, Co-purification, Reconstituted Complex |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
3 |
2 |
3 |
Positive Genetic, Negative Genetic, Negative Genetic |
MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
3 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
NPR2 |
YEL062W |
Subunit of the Iml1p/SEACIT complex |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
2 |
2 |
2 |
Affinity Capture-RNA, Affinity Capture-MS |
NUP157 |
YER105C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DUG1 |
YFR044C |
Cys-Gly metallo-di-peptidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FAR7 |
YFR008W |
Protein involved in recovery from pheromone-induced cell cycle arrest |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ALD5 |
YER073W |
Mitochondrial aldehyde dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAD28 |
YDR030C |
Protein involved in DNA repair |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
APM4 |
YOL062C |
Cargo-binding mu subunit of AP-2 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ENT3 |
YJR125C |
Protein containing an N-terminal epsin-like domain |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FAR3 |
YMR052W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PPG1 |
YNR032W |
Serine protein phosphatase involved in formation of FAR complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAL1 |
YDR348C |
Protein of unknown function thought to be involved in endocytosis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RLM1 |
YPL089C |
MADS-box transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BCS1 |
YDR375C |
Protein translocase and chaperone required for Complex III assembly |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DUS3 |
YLR401C |
Dihydrouridine synthase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
EXP1 |
YDL121C |
A cargo receptor protein for Pma1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BNA1 |
YJR025C |
3-hydroxyanthranilic acid dioxygenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TRM1 |
YDR120C |
tRNA methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STB5 |
YHR178W |
Transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YIR043C |
YIR043C |
Blocked reading frame |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SNX4 |
YJL036W |
Sorting nexin |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TVP38 |
YKR088C |
Integral membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TAL1 |
YLR354C |
Transaldolase, enzyme in the non-oxidative pentose phosphate pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YML100W-A |
YML100W-A |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPT7 |
YML001W |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YNL046W |
YNL046W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YOL036W |
YOL036W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SER1 |
YOR184W |
3-phosphoserine aminotransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TKL1 |
YPR074C |
Transketolase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AGE2 |
YIL044C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DOT5 |
YIL010W |
Nuclear thiol peroxidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MDM38 |
YOL027C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ARO7 |
YPR060C |
Chorismate mutase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MAK31 |
YCR020C-A |
Non-catalytic subunit of N-terminal acetyltransferase of the NatC type |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FAU1 |
YER183C |
5,10-methenyltetrahydrofolate synthetase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PKP1 |
YIL042C |
Mitochondrial protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ILT1 |
YDR090C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP100 |
YKL068W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Reconstituted Complex |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADH1 |
YOL086C |
Alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Positive Genetic |
BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP43 |
YCR035C |
Exosome non-catalytic core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HPR1 |
YDR138W |
Subunit of THO/TREX complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUD1 |
YBR119W |
U1 snRNP A protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAP95 |
YLR347C |
Karyopherin beta |
physical |
1 |
1 |
1 |
Reconstituted Complex |
ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP82 |
YJL061W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF6 |
YDR496C |
Pumilio-homology domain protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADE13 |
YLR359W |
Adenylosuccinate lyase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIC96 |
YFR002W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP159 |
YIL115C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OST1 |
YJL002C |
Alpha subunit of the oligosaccharyltransferase complex of the ER lumen |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
1 |
1 |
1 |
Negative Genetic |
MKT1 |
YNL085W |
Protein similar to nucleases that forms a complex with Pbp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NAS6 |
YGR232W |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSN9 |
YDR179C |
Subunit of the Cop9 signalosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC13 |
YLR208W |
Structural component of 3 complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC65 |
YML105C |
Subunit of the signal recognition particle (SRP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LTV1 |
YKL143W |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DTD1 |
YDL219W |
D-Tyr-tRNA(Tyr) deacylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MSD1 |
YPL104W |
Mitochondrial aspartyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAR8 |
YMR029C |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Negative Genetic |
NGL2 |
YMR285C |
Protein involved in 5.8S rRNA processing |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSR2 |
YPR030W |
Nuclear ubiquitin protein ligase binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GDE1 |
YPL110C |
Glycerophosphocholine (GroPCho) phosphodiesterase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
DIP5 |
YPL265W |
Dicarboxylic amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSR1 |
YLL010C |
Plasma membrane-associated protein phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPA1 |
YJR141W |
Protein implicated in pre-mRNA processing and proteasomal degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRM2 |
YIL037C |
Pheromone-regulated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
1 |
1 |
1 |
Negative Genetic |
KIN2 |
YLR096W |
S/T protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DIA2 |
YOR080W |
Origin-binding F-box protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DAK2 |
YFL053W |
Dihydroxyacetone kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DUF1 |
YOL087C |
Ubiquitin-binding protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRS5 |
YOL061W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMD1 |
YER132C |
Protein with an N-terminal kelch-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
APE3 |
YBR286W |
Vacuolar aminopeptidase Y |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ROD1 |
YOR018W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GDH2 |
YDL215C |
NAD(+)-dependent glutamate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
genetic |
1 |
1 |
1 |
Negative Genetic |
IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTQ2 |
YDR140W |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
EBS1 |
YDR206W |
Protein involved in translation inhibition and nonsense-mediated decay |
genetic |
1 |
1 |
1 |
Positive Genetic |
COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAC3 |
YDR159W |
mRNA export factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
HPC2 |
YBR215W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MOT2 |
YER068W |
Ubiquitin-protein ligase subunit of the CCR4-NOT complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MTR2 |
YKL186C |
mRNA transport regulator |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RFM1 |
YOR279C |
Component of the Sum1p-Rfm1p-Hst1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC61 |
YLR378C |
Conserved ER protein translocation channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RCY1 |
YJL204C |
F-box protein involved in recycling endocytosed proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARG80 |
YMR042W |
Transcription factor involved in regulating arginine-responsive genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRI2 |
YOL117W |
Subunit of the COP9 signalosome (CSN) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DCN1 |
YLR128W |
Scaffold-type E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC19 |
YAL038W |
Pyruvate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CUS2 |
YNL286W |
Putative checkpoint factor in transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCA1 |
YOR197W |
Ca2+-dependent cysteine protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERV29 |
YGR284C |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
NVJ1 |
YHR195W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAP120 |
YPL125W |
Karyopherin responsible for the nuclear import of Rpf1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG5 |
YMR015C |
C-22 sterol desaturase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EUC1 |
YMR111C |
Sequence-specific DNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
POM152 |
YMR129W |
Glycoprotein subunit of transmembrane ring of nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTB1 |
YDR221W |
Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
GAT2 |
YMR136W |
Protein containing GATA family zinc finger motifs |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HTD2 |
YHR067W |
Mitochondrial 3-hydroxyacyl-thioester dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET10 |
YFR030W |
Subunit alpha of assimilatory sulfite reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUL3 |
YGR003W |
Ubiquitin-protein ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSD2 |
YGR170W |
Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMP21 |
YIL154C |
Transcriptional activator involved in maintenance of ion homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT101 |
YJL047C |
Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEF1 |
YLR069C |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
COA4 |
YLR218C |
Twin Cx(9)C protein involved in cytochrome c oxidase organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRE28 |
YDR532C |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PTH2 |
YBL057C |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMB1 |
YER029C |
Core Sm protein Sm B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
physical |
1 |
1 |
1 |
Biochemical Activity |
URA2 |
YJL130C |
Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPO7 |
YAL009W |
Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSR2 |
YLR435W |
Protein with a potential role in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOL3 |
YHR163W |
6-phosphogluconolactonase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF4632 |
YGL049C |
Translation initiation factor eIF4G and scaffold protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRM9 |
YML014W |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPO12 |
YHR152W |
Nucleolar protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAH1 |
YCR060W |
Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SOL2 |
YCR073W-A |
Protein with a possible role in tRNA export |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLH1 |
YGR271W |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Positive Genetic |
YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Positive Genetic |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSF2 |
YDR312W |
Protein required for ribosomal large subunit maturation |
genetic |
1 |
1 |
1 |
Positive Genetic |
TSA2 |
YDR453C |
Stress inducible cytoplasmic thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Positive Genetic |
SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
genetic |
1 |
1 |
1 |
Positive Genetic |
YMR226C |
YMR226C |
NADP(+)-dependent serine dehydrogenase and carbonyl reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
SHR5 |
YOL110W |
Palmitoyltransferase subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRM11 |
YOL124C |
Catalytic subunit of adoMet-dependent tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
SKI7 |
YOR076C |
GTP-binding protein that couples the Ski complex and exosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
1 |
1 |
1 |
Positive Genetic |
THI72 |
YOR192C |
Transporter of thiamine or related compound |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
1 |
1 |
1 |
Positive Genetic |
ULA1 |
YPL003W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPE3 |
YPR069C |
Spermidine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF8 |
YML114C |
TFIID subunit (65 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VVS1 |
YBR241C |
Putative transporter, member of the sugar porter family |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF11 |
YDR073W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR124W |
YDR124W |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
STP1 |
YDR463W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHU1 |
YHL006C |
Component of Shu complex (aka PCSS complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUC2 |
YIL162W |
Invertase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZRT3 |
YKL175W |
Vacuolar membrane zinc transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRP3 |
YKL211C |
Indole-3-glycerol-phosphate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBR2 |
YLR024C |
Cytoplasmic ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
UCC1 |
YLR224W |
F-box protein and component of SCF ubiquitin ligase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHM2 |
YMR241W |
Citrate and oxoglutarate carrier protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL143C |
YNL143C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCB1 |
YOR086C |
Lipid-binding ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLP1 |
YOR154W |
Glycosylated integral ER membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR292C |
YOR292C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPL257W |
YPL257W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
1 |
1 |
1 |
Positive Genetic |
COM2 |
YER130C |
Transcription factor that binds IME1 Upstream Activation Signal (UAS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CGR1 |
YGL029W |
Protein involved in nucleolar integrity and processing of pre-rRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
LCB3 |
YJL134W |
Long-chain base-1-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAL9 |
YOL089C |
Putative transcription factor containing a zinc finger |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG41 |
YPL250C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
CWC27 |
YPL064C |
Component of a complex containing Cef1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB4 |
YOR171C |
Sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTO1 |
YGL236C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
APS3 |
YJL024C |
Small subunit of the clathrin-associated adaptor complex AP-3 |
genetic |
1 |
1 |
1 |
Positive Genetic |
CHM7 |
YJL049W |
Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Positive Genetic |
OPT2 |
YPR194C |
Oligopeptide transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Positive Genetic |
MTC4 |
YBR255W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRX15 |
YNR040W |
Membrane-associated mitoribosome receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPM2 |
YOL141W |
AdoMet-dependent tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRE1 |
YPL223C |
Hydrophilin essential in desiccation-rehydration process |
genetic |
1 |
1 |
1 |
Positive Genetic |
PUS2 |
YGL063W |
Mitochondrial tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM9 |
YMR063W |
Plasma membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRT8 |
YOL048C |
Protein involved in spore wall assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |