| BNI1 |
YNL271C |
Formin |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
physical |
3 |
2 |
1 |
Two-hybrid, Two-hybrid, Affinity Capture-MS |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MTR4 |
YJL050W |
RNA duplex-sensing translocase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KKQ8 |
YKL168C |
Putative serine/threonine protein kinase with unknown cellular role |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IKI1 |
YHR187W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
| AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HSP30 |
YCR021C |
Negative regulator of the H(+)-ATPase Pma1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PTP3 |
YER075C |
Phosphotyrosine-specific protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SKM1 |
YOL113W |
Member of the PAK family of serine/threonine protein kinases |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MSC1 |
YML128C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| GPI1 |
YGR216C |
Membrane protein involved in the synthesis of GlcNAc-PI |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-MS |
| GDI1 |
YER136W |
GDP dissociation inhibitor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CEF1 |
YMR213W |
Essential splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPI1 |
YHR085W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AXL2 |
YIL140W |
Integral plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC42 |
YLR229C |
Small rho-like GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MDM20 |
YOL076W |
Non-catalytic subunit of the NatB N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPE1 |
YKL059C |
Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC45 |
YLR103C |
DNA replication initiation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMG1 |
YCR046C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL10 |
YNL284C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRPL24 |
YMR193W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL9 |
YGR220C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPS28 |
YDR337W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MUM2 |
YBR057C |
Protein essential for meiotic DNA replication and sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CAM1 |
YPL048W |
One of two isoforms of the gamma subunit of eEF1B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KOG1 |
YHR186C |
Subunit of TORC1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG11 |
YPR049C |
Adapter protein for pexophagy and the Cvt targeting pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG27 |
YLR100W |
3-keto sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUG2 |
YBR281C |
Component of glutamine amidotransferase (GATase II) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| IPA1 |
YJR141W |
Protein implicated in pre-mRNA processing and proteasomal degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GPN3 |
YLR243W |
Putative GTPase with a role in biogenesis of RNA pol II and polIII |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUD9 |
YGR041W |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAL1 |
YDR021W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DEF1 |
YKL054C |
RNAPII degradation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPA1 |
YHR005C |
Subunit of G protein involved in pheromone response |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| FCF1 |
YDR339C |
PINc domain endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APE2 |
YKL157W |
Aminopeptidase yscII |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM10 |
YIL150C |
Essential chromatin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAS2 |
YDR020C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM1 |
YMR043W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCD1 |
YHR144C |
Deoxycytidine monophosphate (dCMP) deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MYO5 |
YMR109W |
One of two type I myosin motors |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATS1 |
YAL020C |
Protein required for modification of wobble nucleosides in tRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOB1 |
YIL106W |
Component of the mitotic exit network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBS2 |
YDR197W |
Mitochondrial translational activator of the COB mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG1 |
YBR110W |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAE1 |
YKR038C |
Highly conserved ATPase of HSP70/DnaK family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI17 |
YDR434W |
Transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERP5 |
YHR110W |
Protein with similarity to Emp24p and Erv25p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG13 |
YGL047W |
Catalytic component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET7 |
YOR241W |
Folylpolyglutamate synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HXT2 |
YMR011W |
High-affinity glucose transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TUM1 |
YOR251C |
Rhodanese domain sulfur transferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PDI1 |
YCL043C |
Protein disulfide isomerase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP4 |
YBR257W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SDH7 |
YDR511W |
Mitochondrial protein involved in assembly of succinate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| USE1 |
YGL098W |
Essential SNARE protein localized to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKR104W |
YKR104W |
Putative transporter of the MRP subfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF8 |
YML114C |
TFIID subunit (65 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP28 |
YDR243C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL4B |
YDR012W |
Ribosomal 60S subunit protein L4B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TMA64 |
YDR117C |
Protein of unknown function that associates with ribosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOM1 |
YEL059C-A |
Subunit of the mitochondrial inner membrane peptidase (IMP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YGL114W |
YGL114W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PIH1 |
YHR034C |
Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Positive Genetic |
| QCR8 |
YJL166W |
Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RCF1 |
YML030W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFC1 |
YBR123C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUS1 |
YDL193W |
Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NHP2 |
YDL208W |
Protein related to mammalian high mobility group (HMG) proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RLI1 |
YDR091C |
Essential Fe-S protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPP41 |
YDR464W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TLG1 |
YDR468C |
Essential t-SNARE that mediates fusion of vesicles with the late Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP7 |
YER082C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VRG4 |
YGL225W |
Golgi GDP-mannose transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP4 |
YHR069C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM54 |
YJL054W |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAM18 |
YLR008C |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRB1 |
YMR131C |
Specific assembly chaperone for ribosomal protein Rpl3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMP3 |
YOR149C |
Alpha 1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP15 |
YPR143W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP14 |
YDL148C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLD3 |
YGL113W |
Protein involved in the initiation of DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAM35 |
YHR083W |
Component of the sorting and assembly machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHQ1 |
YIL104C |
Chaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRI1 |
YIR008C |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN7 |
YJL025W |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC2 |
YJR068W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRI2 |
YKL045W |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT4 |
YLR305C |
Phosphatidylinositol-4-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPK3 |
YBR028C |
AGC kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB5 |
YDR079C-A |
Component of RNA polymerase II general transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRP4 |
YDR354W |
Anthranilate phosphoribosyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR415C |
YDR415C |
Putative aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RML2 |
YEL050C |
Mitochondrial ribosomal protein of the large subunit (L2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER188C-A |
YER188C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THI5 |
YFL058W |
Protein involved in synthesis of the thiamine precursor HMP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL242C |
YGL242C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM21 |
YGR033C |
Nonessential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPO2 |
YGR138C |
Polyamine transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR273C |
YGR273C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCD1 |
YHR003C |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PCL5 |
YHR071W |
Cyclin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCD2 |
YKL027W |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBR2 |
YLR024C |
Cytoplasmic ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAG1 |
YLR173W |
Vacuolar membrane protein involved in termination of autophagy |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS36 |
YLR417W |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR315W |
YMR315W |
Protein with NADP(H) oxidoreductase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS28 |
YPL065W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR015C |
YPR015C |
Putative zinc finger transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POM34 |
YLR018C |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| FMC1 |
YIL098C |
Mitochondrial matrix protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CMC2 |
YBL059C-A |
Protein involved in respiratory chain complex assembly or maintenance |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GEX2 |
YKR106W |
Proton:glutathione antiporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GRE1 |
YPL223C |
Hydrophilin essential in desiccation-rehydration process |
genetic |
1 |
1 |
1 |
Negative Genetic |
