Standard name Systematic name Name description Description
SHQ1 YIL104C Chaperone protein Chaperone protein; required for the assembly of box H/ACA snoRNPs and thus for pre-rRNA processing; functions as an RNA mimic; forms a complex with Naf1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; homology with known Hsp90p cochaperones; relocalizes to the cytosol in response to hypoxia
Visualize the interactome of SHQ1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.073 NaN NaN
Nucleus 0.956 0.947 0.780
Vac/Vac Memb NaN 0.070 0.203
Cytoplasm NaN NaN 0.091

GFP localization & abundance

GFP localization GFP abundance
nucleus 7060

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SHQ1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 7 4 5 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-crystal Structure, Affinity Capture-MS, Co-crystal Structure, Reconstituted Complex
NAF1 YNL124W RNA-binding protein required for the assembly of box H/ACA snoRNPs physical 2 2 2 Reconstituted Complex, Two-hybrid
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 2 1 2 Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
NOP10 YHR072W-A Subunit of box H/ACA snoRNP complex physical 2 2 1 Co-crystal Structure, Reconstituted Complex
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 1 1 1 DNA to cDNA expression microarray evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HAP4 YKL109W Transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing genetic 1 1 1 Negative Genetic
HAS1 YMR290C ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Negative Genetic
KEL3 YPL263C Cytoplasmic protein of unknown function genetic 1 1 1 Negative Genetic
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs genetic 1 1 1 Negative Genetic
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex physical 1 1 1 Co-crystal Structure
NHP2 YDL208W Protein related to mammalian high mobility group (HMG) proteins physical 1 1 1 Reconstituted Complex
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Negative Genetic
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
PRE8 YML092C Alpha 2 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) physical 1 1 1 Two-hybrid
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Positive Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Positive Genetic
CYR1 YJL005W Adenylate cyclase genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
CTO1 YCR015C Protein required for cold tolerance genetic 1 1 1 Negative Genetic
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Negative Genetic
IMG1 YCR046C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MHR1 YDR296W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Positive Genetic
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC genetic 1 1 1 Negative Genetic
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 1 1 1 Negative Genetic
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Reconstituted Complex
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 1 1 1 Dosage Lethality
PKH2 YOL100W Serine/threonine protein kinase physical 1 1 1 Reconstituted Complex
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 1 1 1 Negative Genetic
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis genetic 1 1 1 Negative Genetic
LAS1 YKR063C Endonuclease involved in pre-rRNA processing at both ends of ITS2 genetic 1 1 1 Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
PTC2 YER089C Type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
DEF1 YKL054C RNAPII degradation factor genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
AZF1 YOR113W Zinc-finger transcription factor genetic 1 1 1 Negative Genetic
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 1 1 1 Negative Genetic
DBP6 YNR038W Essential protein involved in ribosome biogenesis genetic 1 1 1 Negative Genetic
NOP8 YOL144W Nucleolar protein required for 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
ASG1 YIL130W Zinc cluster protein proposed to be a transcriptional regulator genetic 1 1 1 Negative Genetic
PBN1 YCL052C Component of glycosylphosphatidylinositol-mannosyltransferase I genetic 1 1 1 Negative Genetic
PHO11 YAR071W One of three repressible acid phosphatases genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family genetic 1 1 1 Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
CHS6 YJL099W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Negative Genetic
AIM29 YKR074W Protein of unknown function genetic 1 1 1 Negative Genetic
SET4 YJL105W Chromatin-associated protein involved in control of stress response genetic 1 1 1 Negative Genetic
RBA50 YDR527W Protein involved in transcription genetic 1 1 1 Negative Genetic
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 1 1 1 Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Positive Genetic
BCD1 YHR040W Essential protein required for the accumulation of box C/D snoRNA genetic 1 1 1 Negative Genetic
DBR1 YKL149C RNA lariat debranching enzyme genetic 1 1 1 Negative Genetic
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Synthetic Lethality
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Positive Genetic
YHL042W YHL042W Endoplasmic reticulum protein genetic 1 1 1 Positive Genetic
YJL136W-A YJL136W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
YLR154C-H YLR154C-H Putative protein of unknown function genetic 1 1 1 Positive Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
SNU13 YEL026W RNA binding protein genetic 1 1 1 Negative Genetic
ZPR1 YGR211W Essential protein with two zinc fingers genetic 1 1 1 Negative Genetic
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
SPC42 YKL042W Central plaque component of spindle pole body (SPB) genetic 1 1 1 Negative Genetic
UTP23 YOR004W Component of the small subunit processome genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
SHY1 YGR112W Mitochondrial inner membrane protein required for complex IV assembly genetic 1 1 1 Negative Genetic
YGR122W YGR122W Protein that may be involved in pH regulation genetic 1 1 1 Negative Genetic
TMA19 YKL056C Protein that associates with ribosomes genetic 1 1 1 Negative Genetic
SRP40 YKR092C Nucleolar serine-rich protein genetic 1 1 1 Negative Genetic
YLR264C-A YLR264C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TSR3 YOR006C Protein required for 20S pre-rRNA processing genetic 1 1 1 Negative Genetic
YPL068C YPL068C Protein of unknown function genetic 1 1 1 Negative Genetic
MIN3 YMR182W-A Mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic