Standard name Systematic name Name description Description
APM4 YOL062C Cargo-binding mu subunit of AP-2 Cargo-binding mu subunit of AP-2; AP-2 is a heterotetrameric endocytic cargo-binding adaptor that facilitates uptake of membrane proteins during clathrin-mediated endocytosis; Apm4p is required for AP-2 function and localization, and binds cell wall stress receptor Mid2p; AP-2 is required for cell polarity responses to pheromone, nutritional status and cell wall damage in S. cerevisiae, and for hyphal growth in C. albicans; AP-2 complex is conserved in mammals
Visualize the interactome of APM4
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.143 0.196 0.123
Budneck 0.076 NaN 0.091
Budsite 0.201 0.113 0.158
Cell Periphery 0.134 0.119 0.120
Cort. Patches 0.464 0.588 0.430
Cytoplasm 0.170 0.216 0.164
ER 0.071 0.067 0.061
Mito 0.107 0.155 0.067
Peroxisome 0.071 NaN 0.135
SpindlePole 0.058 NaN 0.132

GFP localization & abundance

GFP localization GFP abundance
bud neck, cell periphery 3410

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
APM4 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
APL1 YJR005W Beta-adaptin physical 4 3 4 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid
APL3 YBL037W Alpha-adaptin physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
REI1 YBR267W Cytoplasmic pre-60S factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PCA1 YBR295W Cadmium transporting P-type ATPase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
APS2 YJR058C Small subunit of the clathrin-associated adaptor complex AP-2 physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 2 1 2 Negative Genetic, Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 1 2 Negative Genetic, Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 2 1 2 Positive Genetic, Positive Genetic
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 2 1 1 Negative Genetic, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 2 1 1 Negative Genetic, Negative Genetic
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Positive Genetic
SEC53 YFL045C Phosphomannomutase physical 1 1 1 Affinity Capture-MS
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases physical 1 1 1 Biochemical Activity
GRX6 YDL010W Cis-Golgi localized monothiol glutaredoxin, binds Fe-S cluster physical 1 1 1 Co-fractionation
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 Reconstituted Complex
PKC1 YBL105C Protein serine/threonine kinase physical 1 1 1 Two-hybrid
NCE103 YNL036W Carbonic anhydrase physical 1 1 1 Two-hybrid
RAD18 YCR066W E3 ubiquitin ligase physical 1 1 1 Two-hybrid
GEA1 YJR031C Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) physical 1 1 1 Two-hybrid
FUN12 YAL035W Translation initiation factor eIF5B physical 1 1 1 Two-hybrid
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) physical 1 1 1 Two-hybrid
DMA1 YHR115C Ubiquitin-protein ligase (E3) physical 1 1 1 Two-hybrid
ATG11 YPR049C Adapter protein for pexophagy and the Cvt targeting pathway physical 1 1 1 Two-hybrid
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
ATG31 YDR022C Autophagy-specific protein required for autophagosome formation physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
TDA5 YLR426W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
YAR066W YAR066W Putative GPI protein genetic 1 1 1 Negative Genetic
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Lethality
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 1 1 1 Synthetic Rescue
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic