CSH1 |
YBR161W |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
12 |
4 |
10 |
Synthetic Lethality, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
10 |
2 |
7 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
9 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Rescue, Synthetic Rescue, Negative Genetic, Negative Genetic, Synthetic Rescue |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
8 |
2 |
6 |
Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
8 |
2 |
6 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
7 |
4 |
4 |
Synthetic Lethality, Dosage Rescue, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
6 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
6 |
2 |
2 |
Negative Genetic, Negative Genetic, Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
5 |
3 |
5 |
Synthetic Rescue, Phenotypic Suppression, Positive Genetic, Positive Genetic, Positive Genetic |
VPS74 |
YDR372C |
Golgi PI4K effector, PtdIns4P sensor, and retention receptor |
genetic |
5 |
3 |
5 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Lethality, Negative Genetic |
SUR2 |
YDR297W |
Sphinganine C4-hydroxylase |
genetic |
5 |
2 |
5 |
Positive Genetic, Positive Genetic, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
5 |
3 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Rescue, Synthetic Lethality |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
5 |
2 |
4 |
Phenotypic Suppression, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GEF1 |
YJR040W |
Voltage-gated chloride channel |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
LCB5 |
YLR260W |
Minor sphingoid long-chain base kinase |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
5 |
3 |
3 |
Synthetic Rescue, Positive Genetic, Positive Genetic, Positive Genetic, Negative Genetic |
YEH2 |
YLR020C |
Steryl ester hydrolase |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ERG4 |
YGL012W |
C-24(28) sterol reductase |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect |
ISC1 |
YER019W |
Inositol phosphosphingolipid phospholipase C |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
4 |
3 |
3 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Rescue |
PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
4 |
3 |
3 |
Positive Genetic, Synthetic Growth Defect, Synthetic Rescue, Positive Genetic |
ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Rescue |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Positive Genetic, Negative Genetic |
SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ELO3 |
YLR372W |
Elongase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEI1 |
YLR404W |
Seipin involved in lipid droplet (LD) assembly |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
3 |
3 |
3 |
Negative Genetic, Positive Genetic, Synthetic Growth Defect |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
3 |
3 |
3 |
Synthetic Growth Defect, Negative Genetic, Synthetic Lethality |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
3 |
3 |
3 |
Positive Genetic, Synthetic Rescue, Negative Genetic |
CCC2 |
YDR270W |
Cu(+2)-transporting P-type ATPase |
genetic |
3 |
3 |
3 |
Phenotypic Suppression, Dosage Rescue, Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
3 |
2 |
3 |
Dosage Rescue, Dosage Rescue, Negative Genetic |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
3 |
2 |
3 |
Dosage Rescue, Negative Genetic, Negative Genetic |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
MNL2 |
YLR057W |
Putative mannosidase involved in ER-associated protein degradation |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Lethality, Negative Genetic |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
FAT1 |
YBR041W |
Very long chain fatty acyl-CoA synthetase and fatty acid transporter |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
STR2 |
YJR130C |
Cystathionine gamma-synthase, converts cysteine into cystathionine |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
3 |
3 |
2 |
Synthetic Lethality, Phenotypic Enhancement, Negative Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
3 |
2 |
2 |
Positive Genetic, Synthetic Rescue, Synthetic Rescue |
CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPS4B |
YHR203C |
Protein component of the small (40S) ribosomal subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MVD1 |
YNR043W |
Mevalonate pyrophosphate decarboxylase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TVS1 |
YCR061W |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PTM1 |
YKL039W |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPS18B |
YML026C |
Protein component of the small (40S) ribosomal subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MTC6 |
YHR151C |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
LAT1 |
YNL071W |
Dihydrolipoamide acetyltransferase component (E2) of the PDC |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Lethality |
PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Lethality |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
ERG5 |
YMR015C |
C-22 sterol desaturase |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
CCC1 |
YLR220W |
Vacuolar Fe2+/Mn2+ transporter |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Growth Defect |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Rescue |
SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
CHO1 |
YER026C |
Phosphatidylserine synthase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Enhancement |
LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GPT2 |
YKR067W |
Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAD1 |
YPL022W |
Single-stranded DNA endonuclease (with Rad10p) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CNB1 |
YKL190W |
Calcineurin B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NOP6 |
YDL213C |
rRNA-binding protein required for 40S ribosomal subunit biogenesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BUD32 |
YGR262C |
Protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPO12 |
YHR152W |
Nucleolar protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LUG1 |
YLR352W |
Protein of unknown function with similarity to F-box proteins |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AFG3 |
YER017C |
Mitochondrial inner membrane m-AAA protease component |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ISY1 |
YJR050W |
Member of the NineTeen Complex (NTC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRS1 |
YIR021W |
Splicing protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SGM1 |
YJR134C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SYG1 |
YIL047C |
Plasma membrane protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YKR018C |
YKR018C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPT31 |
YER031C |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPT1 |
YFL038C |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS55 |
YJR044C |
Late endosomal protein involved in late endosome to vacuole transport |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TOS1 |
YBR162C |
Covalently-bound cell wall protein of unknown function |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL37A |
YLR185W |
Ribosomal 60S subunit protein L37A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DSF1 |
YEL070W |
Mannitol dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PHO13 |
YDL236W |
Conserved phosphatase acting as a metabolite repair enzyme |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS29B |
YDL061C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RKM4 |
YDR257C |
Ribosomal lysine methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PYP1 |
YNL010W |
Sugar alcohol phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AIM14 |
YGL160W |
NADPH oxidase localized to the perinuclear ER |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COX9 |
YDL067C |
Subunit VIIa of cytochrome c oxidase (Complex IV) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FYV7 |
YLR068W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RPS28B |
YLR264W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SDT1 |
YGL224C |
Pyrimidine nucleotidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
EAF6 |
YJR082C |
Subunit of the NuA4 acetyltransferase complex |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Growth Defect |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
IPI1 |
YHR085W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
NUC1 |
YJL208C |
Major mitochondrial nuclease |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
AEP2 |
YMR282C |
Mitochondrial protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CDC53 |
YDL132W |
Cullin |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ERG27 |
YLR100W |
3-keto sterol reductase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DOP1 |
YDR141C |
Protein involved in vesicular transport at trans-Golgi network (TGN) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SSS1 |
YDR086C |
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YTA12 |
YMR089C |
Mitochondrial inner membrane m-AAA protease component |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VPS68 |
YOL129W |
Vacuolar membrane protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
UTP9 |
YHR196W |
Nucleolar protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
UTP15 |
YMR093W |
Nucleolar protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YSY6 |
YBR162W-A |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MIP1 |
YOR330C |
Mitochondrial DNA polymerase gamma |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPL29 |
YFR032C-A |
Ribosomal 60S subunit protein L29 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PSD2 |
YGR170W |
Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MSS51 |
YLR203C |
Specific translational activator for the mitochondrial COX1 mRNA |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GEP5 |
YLR091W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
NMT1 |
YLR195C |
N-myristoyl transferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
RSF1 |
YMR030W |
Protein required for respiratory growth |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPS16B |
YDL083C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HER2 |
YMR293C |
Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DLT1 |
YMR126C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPS29A |
YLR388W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MTC4 |
YBR255W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BFR2 |
YDR299W |
Component of the SSU and 90S preribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
STT4 |
YLR305C |
Phosphatidylinositol-4-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK16 |
YAL025C |
Essential nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP16 |
YER002W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL17A |
YKL180W |
Ribosomal 60S subunit protein L17A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL38 |
YLR325C |
Ribosomal 60S subunit protein L38 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMH1 |
YLR309C |
Protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMP1 |
YLR145W |
Subunit of RNase MRP |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP45 |
YAL032C |
Protein required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
LTO1 |
YNL260C |
Substrate-specific adaptor protein involved in apo-Rli1p maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIP2 |
YLR129W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP7 |
YCL031C |
Essential protein involved in rRNA processing and ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP4 |
YHR069C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP42 |
YDL111C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARX1 |
YDR101C |
Nuclear export factor for the ribosomal pre-60S subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
PWP1 |
YLR196W |
Protein with WD-40 repeats involved in rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCP1 |
YDR361C |
Essential nuclear chaperone for ribosomal protein Rpl23p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADE4 |
YMR300C |
Phosphoribosylpyrophosphate amidotransferase (PRPPAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
BAT1 |
YHR208W |
Mitochondrial branched-chain amino acid (BCAA) aminotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX5A |
YNL052W |
Subunit Va of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERP1 |
YAR002C-A |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
GDI1 |
YER136W |
GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HTB2 |
YBL002W |
Histone H2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACK1 |
YDL203C |
Protein that functions in the cell wall integrity pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
GEA2 |
YEL022W |
Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAK10 |
YEL053C |
Non-catalytic subunit of the NatC N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MAK5 |
YBR142W |
Essential nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRP7 |
YNL005C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCM1 |
YGR150C |
Mitochondrial 15S rRNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGM101 |
YJR144W |
Protein with a role in mitochondrial DNA recombinational repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTR10 |
YOR160W |
Nuclear import receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
NMD3 |
YHR170W |
Protein involved in nuclear export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
1 |
1 |
1 |
Negative Genetic |
PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOA4 |
YDR069C |
Ubiquitin hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PIM1 |
YBL022C |
ATP-dependent Lon protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP28 |
YDR243C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
LIN1 |
YHR156C |
Non-essential component of U5 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDS3 |
YGL197W |
Putative component of the TOR regulatory pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP14 |
YDL148C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD3 |
YER171W |
5' to 3' DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAM1 |
YDL090C |
Beta subunit of the CAAX farnesyltransferase (FTase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
physical |
1 |
1 |
1 |
PCA |
MRPL6 |
YHR147C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB8 |
YOR224C |
RNA polymerase subunit ABC14.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL23A |
YBL087C |
Ribosomal 60S subunit protein L23A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL2A |
YFR031C-A |
Ribosomal 60S subunit protein L2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC53 |
YDL150W |
RNA polymerase III subunit C53 |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTR3 |
YGR158C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIL1 |
YGR086C |
Eisosome core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
REA1 |
YLR106C |
Huge dynein-related AAA-type ATPase (midasin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
PCA |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC25 |
YLR310C |
Membrane bound guanine nucleotide exchange factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKI6 |
YGR195W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLC1 |
YDL052C |
1-acyl-sn-glycerol-3-phosphate acyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SME1 |
YOR159C |
Core Sm protein Sm E |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPO7 |
YAL009W |
Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIM1 |
YPL266W |
Essential 18S rRNA dimethylase (dimethyladenosine transferase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIO2 |
YNL207W |
Essential serine kinase involved in the processing of 20S pre-rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
BNA3 |
YJL060W |
Kynurenine aminotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC5 |
YMR001C |
Polo-like kinase required for mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADO1 |
YJR105W |
Adenosine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRB1 |
YEL060C |
Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
SER1 |
YOR184W |
3-phosphoserine aminotransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Positive Genetic |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSH49 |
YOR319W |
U2-snRNP associated splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
FYV10 |
YIL097W |
Subunit of GID complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESL2 |
YKR096W |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GYP6 |
YJL044C |
GTPase-activating protein (GAP) for yeast Rab family member Ypt6p |
genetic |
1 |
1 |
1 |
Positive Genetic |
ADK1 |
YDR226W |
Adenylate kinase, required for purine metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
APT1 |
YML022W |
Adenine phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRS6 |
YOR370C |
Rab escort protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAP122 |
YGL016W |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPA2 |
YER020W |
Nucleotide binding alpha subunit of the heterotrimeric G protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPP2 |
YER062C |
DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GID8 |
YMR135C |
Subunit of GID Complex, binds strongly to central component Vid30p |
genetic |
1 |
1 |
1 |
Negative Genetic |
FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSL7 |
YBR133C |
Protein arginine N-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG20 |
YJL167W |
Farnesyl pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MNN9 |
YPL050C |
Subunit of Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
OPY1 |
YBR129C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPK1 |
YNR047W |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OMS1 |
YDR316W |
Protein integral to the mitochondrial membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HMG2 |
YLR450W |
HMG-CoA reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOF1 |
YLL011W |
Protein required for biogenesis of 40S (small) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBP2 |
YHL038C |
Required for splicing of the group I intron bI5 of the COB pre-mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCF1 |
YDR339C |
PINc domain endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSC1 |
YLR241W |
Calcium permeable gated cation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDJ1 |
YFL016C |
Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Positive Genetic |
CYS3 |
YAL012W |
Cystathionine gamma-lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAL2 |
YLR081W |
Galactose permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
APM4 |
YOL062C |
Cargo-binding mu subunit of AP-2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CUE5 |
YOR042W |
Ubiquitin-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
FZF1 |
YGL254W |
Transcription factor involved in sulfite metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
DID4 |
YKL002W |
Class E Vps protein of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENT3 |
YJR125C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Positive Genetic |
GEP4 |
YHR100C |
Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARG81 |
YML099C |
Zinc finger transcription factor involved in arginine-responsive genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Positive Genetic |
PCL2 |
YDL127W |
Cyclin, interacts with cyclin-dependent kinase Pho85p |
genetic |
1 |
1 |
1 |
Negative Genetic |
IKS1 |
YJL057C |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET191 |
YJR034W |
Protein required for assembly of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ5 |
YML110C |
2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
JSN1 |
YJR091C |
Member of the Puf family of RNA-binding proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
SBH2 |
YER019C-A |
Ssh1p-Sss1p-Sbh2p complex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
DLS1 |
YJL065C |
Subunit of ISW2/yCHRAC chromatin accessibility complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMD5 |
YDR255C |
Component of GID Complex that confers ubiquitin ligase (U3) activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLM1 |
YIL105C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRR1 |
YKL116C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Positive Genetic |
CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CWC15 |
YDR163W |
Non-essential protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRC3 |
YLL035W |
Polynucleotide kinase present on rDNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC21 |
YOR074C |
Thymidylate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL9A |
YGL147C |
Ribosomal 60S subunit protein L9A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFH1 |
YLR321C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
PRP2 |
YNR011C |
RNA-dependent DExD/H-box ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL20B |
YOR312C |
Ribosomal 60S subunit protein L20B |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS17B |
YDR447C |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
FRQ1 |
YDR373W |
N-myristoylated calcium-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
MDM12 |
YOL009C |
Mitochondrial outer membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIS1 |
YNL078W |
Protein involved in axial bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
PET111 |
YMR257C |
Mitochondrial translational activator specific for the COX2 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE6 |
YKL209C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEP7 |
YDR323C |
Adaptor protein involved in vesicle-mediated vacuolar protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Positive Genetic |
PHO2 |
YDL106C |
Homeobox transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MST28 |
YAR033W |
Putative integral membrane protein, involved in vesicle formation |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCO1 |
YBR037C |
Copper-binding protein of mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSO1 |
YNR049C |
Lipid-interacting protein in SNARE complex assembly machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESC2 |
YDR363W |
Sumo-like domain protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
LRG1 |
YDL240W |
GTPase-activating protein (GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GNT1 |
YOR320C |
N-acetylglucosaminyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FIR1 |
YER032W |
Protein involved in 3' mRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
RLM1 |
YPL089C |
MADS-box transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
GFD2 |
YCL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIP3 |
YNL257C |
Putative sterol transfer protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP1 |
YBL099W |
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSR1 |
YGR152C |
Ras-type GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENT2 |
YLR206W |
Epsin-like protein required for endocytosis and actin patch assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCH1 |
YGR217W |
Voltage-gated high-affinity calcium channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERT1 |
YBR239C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
VID30 |
YGL227W |
Central component of GID Complex, involved in FBPase degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VID28 |
YIL017C |
GID Complex subunit, serves as adaptor for regulatory subunit Vid24p |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZRT2 |
YLR130C |
Low-affinity zinc transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TGL1 |
YKL140W |
Steryl ester hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI7 |
YLR237W |
Plasma membrane transporter responsible for the uptake of thiamine |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VRG4 |
YGL225W |
Golgi GDP-mannose transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS5 |
YOR069W |
Nexin-1 homolog |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
YIP4 |
YGL198W |
Protein that interacts with Rab GTPases |
genetic |
1 |
1 |
1 |
Positive Genetic |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TLG1 |
YDR468C |
Essential t-SNARE that mediates fusion of vesicles with the late Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
URB2 |
YJR041C |
Protein required for normal metabolism of the rRNA primary transcript |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAE1 |
YJR067C |
Substrate-specific adaptor protein involved in apo-Rli1p maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFA1 |
YKL028W |
TFIIE large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP13 |
YLR222C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP14 |
YML093W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP5 |
YDR398W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTM1 |
YOR272W |
Ribosomal assembly factor and 66S pre-ribosomal particle constituent |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBL071C-B |
YBL071C-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR220C |
YBR220C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR124W |
YDR124W |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VHS1 |
YDR247W |
Cytoplasmic serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR248C |
YDR248C |
Putative gluconokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC8 |
YEL012W |
Ubiquitin-conjugating enzyme that regulates gluconeogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
YER078W-A |
YER078W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TYW3 |
YGL050W |
tRNA methyltransferase required for synthesis of wybutosine |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL114W |
YGL114W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPO2 |
YGR138C |
Polyamine transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR050W-A |
YHR050W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR210C |
YHR210C |
Putative aldose 1-epimerase superfamily protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VHR1 |
YIL056W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIL092W |
YIL092W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIL165C |
YIL165C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL027C |
YJL027C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL047C-A |
YJL047C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL077W-B |
YJL077W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMA22 |
YJR014W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRX1 |
YLR043C |
Cytoplasmic thioredoxin isoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR152C |
YLR152C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR242W-A |
YMR242W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR253C |
YMR253C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSR3 |
YOR006C |
Protein required for 20S pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR186W |
YOR186W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUF1 |
YOR187W |
Mitochondrial translation elongation factor Tu (EF-Tu) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCL042W |
YCL042W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR045W |
YHR045W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPS1 |
YLR120C |
Aspartic protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML108W |
YML108W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZDS1 |
YMR273C |
Protein with a role in regulating Swe1p-dependent polarized growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Negative Genetic |
WSC2 |
YNL283C |
Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOR268C |
YOR268C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
UFE1 |
YOR075W |
t-SNARE protein required for retrograde vesicular traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YNG1 |
YOR064C |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ZIP2 |
YGL249W |
Meiosis-specific protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
UTP30 |
YKR060W |
Subunit of U3-containing 90S preribosome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YSP2 |
YDR326C |
Sterol-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
BSD2 |
YBR290W |
Heavy metal ion homeostasis protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
GGA1 |
YDR358W |
Golgi-localized protein with homology to gamma-adaptin |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSM1 |
YJL103C |
Putative zinc cluster protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MID1 |
YNL291C |
Stretch-activated Ca2+-permeable cation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL11B |
YGR085C |
Ribosomal 60S subunit protein L11B |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERF2 |
YLR246W |
Subunit of a palmitoyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBP1 |
YJL209W |
Mitochondrial protein, regulator of COB mRNA stability and translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDR12 |
YPL058C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
COX19 |
YLL018C-A |
Protein required for cytochrome c oxidase assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET1 |
YKR069W |
S-adenosyl-L-methionine uroporphyrinogen III transmethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU13 |
YEL026W |
RNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTN1 |
YDR233C |
Reticulon protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOT13 |
YKL084W |
Zinc-binding mitochondrial intermembrane space (IMS) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
AUS1 |
YOR011W |
Plasma membrane sterol transporter of the ATP-binding cassette family |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDH3 |
YKL141W |
Subunit of succinate dehydrogenase and of TIM22 translocase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATX1 |
YNL259C |
Cytosolic copper metallochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRA1 |
YLL029W |
Protein involved in negative regulation of iron regulon transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALG1 |
YBR110W |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ3 |
YOL096C |
O-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDP3 |
YLR455W |
Component of the NuA3b histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GDA1 |
YEL042W |
Guanosine diphosphatase located in the Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIC1 |
YLR348C |
Mitochondrial dicarboxylate carrier |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG7 |
YHR072W |
Lanosterol synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCH1 |
YGL038C |
Mannosyltransferase of the cis-Golgi apparatus |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RIM1 |
YCR028C-A |
ssDNA-binding protein essential for mitochondrial genome maintenance |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLO4 |
YOR040W |
Mitochondrial glyoxalase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ10 |
YOL008W |
Coenzyme Q (ubiquinone) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCF2 |
YLR051C |
Nucleolar protein involved in the early steps of 35S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP40 |
YKR092C |
Nucleolar serine-rich protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPP6 |
YNR024W |
Nuclear exosome-associated RNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MVB12 |
YGR206W |
ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAB4 |
YGR277C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOB2 |
YPR117W |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPX1 |
YHR201C |
Exopolyphosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDR10 |
YOR328W |
ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSM24 |
YDR175C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP12 |
YJL180C |
Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COA4 |
YLR218C |
Twin Cx(9)C protein involved in cytochrome c oxidase organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMT1 |
YJL147C |
Translational repressor of the mitochondrial ATP6/8 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCV3 |
YAL044C |
H subunit of the mitochondrial glycine decarboxylase complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
COQ6 |
YGR255C |
Flavin-dependent monooxygenase involved in ubiquinone biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MGR1 |
YCL044C |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPS12 |
YNR036C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSF1 |
YPR047W |
Mitochondrial phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL12A |
YEL054C |
Ribosomal 60S subunit protein L12A |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX32 |
YBR168W |
Peroxisomal integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
COA3 |
YJL062W-A |
Mitochondrial protein required for cytochrome c oxidase assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
PML39 |
YML107C |
Protein required for nuclear retention of unspliced pre-mRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDD2 |
YMR074C |
Protein with homology to human PDCD5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRG1 |
YDR065W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL24A |
YGL031C |
Ribosomal 60S subunit protein L24A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL20A |
YMR242C |
Ribosomal 60S subunit protein L20A |
genetic |
1 |
1 |
1 |
Negative Genetic |
KTR6 |
YPL053C |
Probable mannosylphosphate transferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACL4 |
YDR161W |
Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS7B |
YNL096C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL27 |
YBR282W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL19A |
YBR084C-A |
Ribosomal 60S subunit protein L19A |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHS6 |
YJL099W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISR1 |
YPR106W |
Predicted protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPT1 |
YDR072C |
Inositolphosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL36A |
YMR194W |
Ribosomal 60S subunit protein L36A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
HUT1 |
YPL244C |
Protein with a role in UDP-galactose transport to the Golgi lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYC3 |
YAL039C |
Cytochrome c heme lyase (holocytochrome c synthase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRE8 |
YLR047C |
Protein with sequence similarity to iron/copper reductases |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDX3 |
YBR035C |
Pyridoxine (pyridoxamine) phosphate oxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ENT4 |
YLL038C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORM1 |
YGR038W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Positive Genetic |
ISF1 |
YMR081C |
Serine-rich, hydrophilic protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGR3 |
YMR115W |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCT1 |
YBL011W |
Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ8 |
YGL119W |
ATPase required for ubiquinone biosynthesis and respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
AGE1 |
YDR524C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SSK22 |
YCR073C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTG2 |
YHR168W |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSK1 |
YNL073W |
Mitochondrial lysine-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
QCR8 |
YJL166W |
Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CYC1 |
YJR048W |
Cytochrome c, isoform 1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGS2 |
YOR107W |
Negative regulator of glucose-induced cAMP signaling |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
LIP1 |
YMR298W |
Ceramide synthase subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
COQ2 |
YNR041C |
Para hydroxybenzoate polyprenyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
BXI1 |
YNL305C |
Protein involved in apoptosis |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
BXI1 |
YNL305C |
Protein involved in apoptosis |
genetic |
1 |
1 |
1 |
Dosage Rescue |
MPS3 |
YJL019W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL31B |
YLR406C |
Ribosomal 60S subunit protein L31B |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIP1 |
YEL024W |
Ubiquinol-cytochrome-c reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTR2 |
YKR093W |
Integral membrane peptide transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRT14 |
YIL127C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CGR1 |
YGL029W |
Protein involved in nucleolar integrity and processing of pre-rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NNR2 |
YKL151C |
Widely-conserved NADHX dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMR1 |
YGL250W |
Protein required for meiotic recombination and gene conversion |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHS1 |
YJL097W |
Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTC2 |
YKL098W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIE2 |
YGR227W |
Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX12 |
YLR038C |
Subunit VIb of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IML2 |
YJL082W |
Protein required for clearance of inclusion bodies |
genetic |
1 |
1 |
1 |
Negative Genetic |
MHO1 |
YJR008W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB4 |
YOR171C |
Sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
1 |
1 |
1 |
Positive Genetic |
COX20 |
YDR231C |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
KHA1 |
YJL094C |
Putative K+/H+ antiporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOR7 |
YMR251W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
COX8 |
YLR395C |
Subunit VIII of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPC1 |
YGL080W |
Highly conserved subunit of mitochondrial pyruvate carrier (MPC) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
IGO2 |
YHR132W-A |
Protein required for initiation of G0 program |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMC1 |
YIL098C |
Mitochondrial matrix protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRC18 |
YJL037W |
Protein involved in outer spore wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMC2 |
YBL059C-A |
Protein involved in respiratory chain complex assembly or maintenance |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYT2 |
YKL087C |
Cytochrome c1 heme lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPI8 |
YJL133C-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG12 |
YMR208W |
Mevalonate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AFG1 |
YEL052W |
Protein that may act as a chaperone for cytochrome c oxidase subunits |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CPR8 |
YNR028W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
APS3 |
YJL024C |
Small subunit of the clathrin-associated adaptor complex AP-3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCD4 |
YKL165C |
Protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG8 |
YMR220W |
Phosphomevalonate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL24B |
YGR148C |
Ribosomal 60S subunit protein L24B |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO87 |
YCR037C |
Low-affinity inorganic phosphate (Pi) transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
RBK1 |
YCR036W |
Ribokinase, phosphorylates ribose to ribose-5-phosphate |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMF2 |
YHR050W |
Divalent metal ion transporter involved in manganese homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIN10 |
YDR387C |
Putative transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
ODC1 |
YPL134C |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALK2 |
YBL009W |
Atypical protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
EFM3 |
YJR129C |
S-adenosylmethionine-dependent methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS30B |
YOR182C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET54 |
YGR222W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFA1 |
YDL168W |
Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL37B |
YDR500C |
Ribosomal 60S subunit protein L37B |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET100 |
YDR079W |
Chaperone that facilitates the assembly of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAN6 |
YIL145C |
Pantothenate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
STF1 |
YDL130W-A |
Protein involved in regulation of the mitochondrial F1F0-ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPP41 |
YDR464W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCE101 |
YJL205C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
HPM1 |
YIL110W |
AdoMet-dependent methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RML2 |
YEL050C |
Mitochondrial ribosomal protein of the large subunit (L2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
HEM4 |
YOR278W |
Uroporphyrinogen III synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHY1 |
YGR112W |
Mitochondrial inner membrane protein required for complex IV assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSM26 |
YJR101W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMD9 |
YGL107C |
Mitochondrial protein that controls mitochondrial gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRE7 |
YOL152W |
Putative ferric reductase with similarity to Fre2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPP1 |
YCR026C |
Nucleotide pyrophosphatase/phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IZH1 |
YDR492W |
Membrane protein involved in zinc ion homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
LDB16 |
YCL005W |
Protein involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMT1 |
YBL013W |
Methionyl-tRNA formyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUD25 |
YER014C-A |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Positive Genetic |
KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Positive Genetic |
ADF1 |
YCL058W-A |
Transcriptional repressor encoded by the FYV5 antisense strand |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAY24 |
YPR153W |
Peripheral ER membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTS2 |
YOR077W |
Basic zinc-finger protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNE1 |
YOR350C |
Protein involved in splicing Group I aI5-beta intron from COX1 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
PZF1 |
YPR186C |
Transcription factor IIIA (TFIIIA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCH1 |
YMR034C |
Negative regulator of cytosolic calcium homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |