Standard name Systematic name Name description Description
MIP1 YOR330C Mitochondrial DNA polymerase gamma Mitochondrial DNA polymerase gamma; single subunit of mitochondrial DNA polymerase in yeast, in contrast to metazoan complex of catalytic and accessory subunits; polymorphic in yeast, petites occur more frequently in some lab strains; human ortholog POLG complements yeast mip1 mutant; mutations in human POLG associated with Alpers-Huttenlocher syndrome (AHS), progressive external ophthalmoplegia (PEO), parkinsonism, other mitochondrial diseases
Visualize the interactome of MIP1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Endosome 0.110 NaN NaN
Golgi 0.082 NaN NaN
Mito 0.773 0.919 0.960
Nuc Periphery 0.053 NaN NaN
Peroxisome 0.089 NaN NaN
Vac/Vac Memb 0.128 0.152 NaN
Bud NaN NaN 0.063

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 377

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MIP1 1 0 0 0 2

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SML1 YML058W Ribonucleotide reductase inhibitor genetic 3 3 3 Synthetic Rescue, Phenotypic Suppression, Phenotypic Enhancement
RNR1 YER070W Major isoform of large subunit of ribonucleotide-diphosphate reductase genetic 2 2 2 Dosage Rescue, Phenotypic Suppression
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 2 2 2 Positive Genetic, Synthetic Rescue
MFT1 YML062C Subunit of the THO complex genetic 2 1 2 Positive Genetic, Positive Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 2 Positive Genetic, Positive Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 2 1 2 Negative Genetic, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
POL4 YCR014C DNA polymerase IV genetic 2 1 2 Negative Genetic, Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 2 1 2 Positive Genetic, Positive Genetic
SED1 YDR077W Major stress-induced structural GPI-cell wall glycoprotein physical 2 2 1 Two-hybrid, Affinity Capture-Western
REV3 YPL167C Catalytic subunit of DNA polymerase zeta genetic 2 2 1 Phenotypic Suppression, Phenotypic Enhancement
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 1 Positive Genetic, Positive Genetic
IRA2 YOL081W GTPase-activating protein genetic 2 1 1 Negative Genetic, Negative Genetic
ELO3 YLR372W Elongase genetic 2 1 1 Positive Genetic, Positive Genetic
FMP42 YMR221C Putative protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
ATP1 YBL099W Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 2 1 1 Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 1 1 Positive Genetic, Positive Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 2 1 1 Negative Genetic, Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 2 1 1 Positive Genetic, Positive Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 2 1 1 Negative Genetic, Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 2 1 1 Negative Genetic, Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 2 1 1 Negative Genetic, Negative Genetic
TYW1 YPL207W Iron-sulfur protein required for synthesis of wybutosine modified tRNA genetic 2 1 1 Negative Genetic, Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 2 1 1 Negative Genetic, Negative Genetic
TAZ1 YPR140W Lyso-phosphatidylcholine acyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 2 1 1 Positive Genetic, Positive Genetic
MGR3 YMR115W Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 2 1 1 Negative Genetic, Negative Genetic
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 2 1 1 Positive Genetic, Positive Genetic
EMA19 YLR050C Integral ER membrane protein involved in protein sorting genetic 2 1 1 Negative Genetic, Negative Genetic
MIC60 YKR016W Component of the MICOS complex genetic 2 1 1 Negative Genetic, Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Positive Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 1 1 1 Positive Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
CDC45 YLR103C DNA replication initiation factor genetic 1 1 1 Negative Genetic
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
DOA4 YDR069C Ubiquitin hydrolase genetic 1 1 1 Negative Genetic
HTA1 YDR225W Histone H2A physical 1 1 1 Affinity Capture-MS
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
HTA2 YBL003C Histone H2A genetic 1 1 1 Negative Genetic
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Negative Genetic
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen genetic 1 1 1 Negative Genetic
HTB1 YDR224C Histone H2B physical 1 1 1 Affinity Capture-MS
GPD1 YDL022W NAD-dependent glycerol-3-phosphate dehydrogenase genetic 1 1 1 Negative Genetic
ERG10 YPL028W Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Positive Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Synthetic Growth Defect
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Positive Genetic
MIC19 YFR011C Component of the MICOS complex genetic 1 1 1 Negative Genetic
MDH3 YDL078C Peroxisomal malate dehydrogenase genetic 1 1 1 Negative Genetic
DAL82 YNL314W Positive regulator of allophanate inducible genes genetic 1 1 1 Negative Genetic
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Negative Genetic
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 1 1 1 Positive Genetic
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Positive Genetic
IOC4 YMR044W Member of a complex (Isw1b) with Isw1p and Ioc2p genetic 1 1 1 Positive Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
CQD1 YPL109C UbiB family mitochondrial protein genetic 1 1 1 Negative Genetic
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Phenotypic Enhancement
MSH5 YDL154W Protein of the MutS family genetic 1 1 1 Negative Genetic
RXT3 YDL076C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Negative Genetic
RAD24 YER173W Checkpoint protein genetic 1 1 1 Positive Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Positive Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Positive Genetic
RDH54 YBR073W DNA-dependent ATPase genetic 1 1 1 Positive Genetic
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Positive Genetic
MRX3 YBL095W Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Positive Genetic
OPY1 YBR129C Protein of unknown function genetic 1 1 1 Negative Genetic
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex genetic 1 1 1 Negative Genetic
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 1 1 1 Positive Genetic
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
SLC1 YDL052C 1-acyl-sn-glycerol-3-phosphate acyltransferase genetic 1 1 1 Negative Genetic
YDL157C YDL157C Putative protein of unknown function genetic 1 1 1 Positive Genetic
NRG1 YDR043C Transcriptional repressor genetic 1 1 1 Positive Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 1 1 1 Positive Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
UBC8 YEL012W Ubiquitin-conjugating enzyme that regulates gluconeogenesis genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Negative Genetic
MSP1 YGR028W Highly-conserved N-terminally anchored AAA-ATPase genetic 1 1 1 Negative Genetic
PBP1 YGR178C Component of glucose deprivation induced stress granules genetic 1 1 1 Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease genetic 1 1 1 Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Negative Genetic
SNL1 YIL016W Ribosome-associated protein genetic 1 1 1 Negative Genetic
PKP1 YIL042C Mitochondrial protein kinase genetic 1 1 1 Negative Genetic
RCI37 YIL077C Protein that associates with the large mitoribosomal subunit genetic 1 1 1 Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Negative Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Positive Genetic
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SDH3 YKL141W Subunit of succinate dehydrogenase and of TIM22 translocase genetic 1 1 1 Negative Genetic
OAF3 YKR064W Putative transcriptional repressor with Zn(2)-Cys(6) finger genetic 1 1 1 Negative Genetic
PAM17 YKR065C Constituent of the TIM23 complex genetic 1 1 1 Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Negative Genetic
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Negative Genetic
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase genetic 1 1 1 Negative Genetic
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Positive Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
YNL195C YNL195C Protein of unknown function genetic 1 1 1 Negative Genetic
NNR1 YNL200C NADHX epimerase genetic 1 1 1 Negative Genetic
PSY2 YNL201C Subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 1 1 1 Negative Genetic
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 1 1 1 Negative Genetic
RTT10 YPL183C WD40 domain-containing protein involved in endosomal recycling genetic 1 1 1 Negative Genetic
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Negative Genetic
SAM3 YPL274W High-affinity S-adenosylmethionine permease genetic 1 1 1 Negative Genetic
MSH1 YHR120W DNA-binding protein of the mitochondria genetic 1 1 1 Phenotypic Suppression
REV7 YIL139C Accessory subunit of DNA polymerase zeta genetic 1 1 1 Phenotypic Suppression
REV1 YOR346W Deoxycytidyl transferase genetic 1 1 1 Phenotypic Suppression
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Positive Genetic
MDM31 YHR194W Mitochondrial protein that may have a role in phospholipid metabolism genetic 1 1 1 Negative Genetic
KIP1 YBL063W Kinesin-related motor protein genetic 1 1 1 Negative Genetic
ATF1 YOR377W Alcohol acetyltransferase genetic 1 1 1 Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
GAS5 YOL030W 1,3-beta-glucanosyltransferase genetic 1 1 1 Negative Genetic
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase genetic 1 1 1 Positive Genetic
IZH3 YLR023C Membrane protein involved in zinc ion homeostasis genetic 1 1 1 Negative Genetic
LAM1 YHR155W Putative sterol transfer protein genetic 1 1 1 Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 1 1 1 Positive Genetic
CYC3 YAL039C Cytochrome c heme lyase (holocytochrome c synthase) genetic 1 1 1 Negative Genetic
INP54 YOL065C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Positive Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Negative Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Positive Genetic
DIE2 YGR227W Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase genetic 1 1 1 Positive Genetic
IML2 YJL082W Protein required for clearance of inclusion bodies genetic 1 1 1 Negative Genetic
MIC12 YBR262C Component of the MICOS complex genetic 1 1 1 Negative Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Negative Genetic
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Negative Genetic
AIM19 YIL087C Protein of unknown function genetic 1 1 1 Negative Genetic
BCD1 YHR040W Essential protein required for the accumulation of box C/D snoRNA genetic 1 1 1 Positive Genetic
IMA1 YGR287C Major isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase) genetic 1 1 1 Negative Genetic
AIM36 YMR157C Protein of unknown function genetic 1 1 1 Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
AGP3 YFL055W Low-affinity amino acid permease genetic 1 1 1 Negative Genetic