Standard name Systematic name Name description Description
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis Transcription factor involved in iron utilization and homeostasis; binds consensus site PyPuCACCCPu and activates transcription in response to changes in iron availability; in iron-replete conditions localization is regulated by Grx3p, Grx4p, and Fra2p, and promoter binding is negatively regulated via Grx3p-Grx4p binding; AFT1 has a paralog, AFT2, that arose from the whole genome duplication; relative distribution to the nucleus increases upon DNA replication stress
Visualize the interactome of AFT1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.133 0.161 0.260
Nucleus 0.625 0.537 0.635
Vac/Vac Memb 0.319 0.459 0.146

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
AFT1 5 2 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
AFT2 YPL202C Iron-regulated transcriptional activator genetic 11 5 9 Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Dosage Rescue, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect
GRX3 YDR098C Glutathione-dependent oxidoreductase physical 8 3 6 Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Two-hybrid
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase physical 7 3 4 Two-hybrid, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 4 2 4 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 4 3 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Rescue
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 4 2 2 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
RAD9 YDR217C DNA damage-dependent checkpoint protein physical 4 3 1 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Co-localization
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 3 3 3 Synthetic Growth Defect, Negative Genetic, Positive Genetic
IML3 YBR107C Outer kinetochore protein and component of the Ctf19 complex physical 3 2 3 Two-hybrid, Two-hybrid, Affinity Capture-Western
HTZ1 YOL012C Histone variant H2AZ genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 3 2 3 Negative Genetic, Positive Genetic, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MMT1 YMR177W Putative metal transporter involved in mitochondrial iron accumulation regulation 3 3 2 beta-galactosidase reporter gene assay evidence, chromatin immunoprecipitation-chip evidence, quantitative reverse transcription polymerase chain reaction evidence
NHP6A YPR052C High-mobility group (HMG) protein physical 3 2 2 Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 3 2 2 Negative Genetic, Positive Genetic, Negative Genetic
CUP2 YGL166W Copper-binding transcription factor genetic 3 2 2 Negative Genetic, Phenotypic Suppression, Phenotypic Suppression
RNR1 YER070W Major isoform of large subunit of ribonucleotide-diphosphate reductase regulation 3 3 1 beta-galactosidase reporter gene assay evidence, qualitative western immunoblotting evidence, quantitative reverse transcription polymerase chain reaction evidence
SIT1 YEL065W Ferrioxamine B transporter physical 3 3 1 Two-hybrid, Affinity Capture-Western, Reconstituted Complex
OLE1 YGL055W Delta(9) fatty acid desaturase regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
SIT1 YEL065W Ferrioxamine B transporter regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
FET3 YMR058W Ferro-O2-oxidoreductase regulation 2 2 2 DNA to cDNA expression microarray evidence, northern blot evidence
FTR1 YER145C High affinity iron permease regulation 2 2 2 chromatin immunoprecipitation-chip evidence, northern blot evidence
MRS4 YKR052C Iron transporter of the mitochondrial carrier family regulation 2 2 2 beta-galactosidase reporter gene assay evidence, chromatin immunoprecipitation-chip evidence
FAA1 YOR317W Long chain fatty acyl-CoA synthetase regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
APE1 YKL103C Vacuolar aminopeptidase yscI regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
GRX3 YDR098C Glutathione-dependent oxidoreductase genetic 2 2 2 Phenotypic Suppression, Synthetic Rescue
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase genetic 2 2 2 Phenotypic Suppression, Synthetic Rescue
MAC1 YMR021C Copper-sensing transcription factor genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
MIF2 YKL089W Centromeric CDEIII region binding protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
YFH1 YDL120W Mitochondrial matrix iron chaperone genetic 2 2 2 Phenotypic Suppression, Synthetic Rescue
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane genetic 2 2 2 Synthetic Lethality, Negative Genetic
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 2 2 2 Synthetic Lethality, Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 2 2 2 Dosage Growth Defect, Negative Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 2 2 2 Negative Genetic, Positive Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Positive Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
PFY1 YOR122C Profilin genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
FET3 YMR058W Ferro-O2-oxidoreductase genetic 2 2 2 Phenotypic Suppression, Synthetic Rescue
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
IML3 YBR107C Outer kinetochore protein and component of the Ctf19 complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MCM22 YJR135C Outer kinetochore protein and component of the Ctf3 subcomplex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 2 Negative Genetic, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 2 1 2 Negative Genetic, Negative Genetic
STB5 YHR178W Transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
EDS1 YBR033W Putative zinc cluster protein, predicted to be a transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
MMT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation regulation 2 2 1 beta-galactosidase reporter gene assay evidence, quantitative reverse transcription polymerase chain reaction evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 2 2 1 beta-galactosidase reporter gene assay evidence, quantitative reverse transcription polymerase chain reaction evidence
CYC8 YBR112C General transcriptional co-repressor physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis physical 2 2 1 Two-hybrid, Affinity Capture-Western
MSN5 YDR335W Karyopherin physical 2 2 1 Affinity Capture-Western, Two-hybrid
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 2 2 1 Biochemical Activity, Affinity Capture-Western
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 2 2 1 Synthetic Growth Defect, Dosage Growth Defect
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 2 2 1 Negative Genetic, Positive Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
JAC1 YGL018C Specialized J-protein that functions in Fe-S cluster biogenesis genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AFT2 YPL202C Iron-regulated transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation regulation 1 1 1 protein kinase assay evidence
ACO1 YLR304C Aconitase regulation 1 1 1 DNA to cDNA expression microarray evidence
AGA2 YGL032C Adhesion subunit of a-agglutinin of a-cells regulation 1 1 1 DNA to cDNA expression microarray evidence
YGL039W YGL039W Aldehyde reductase regulation 1 1 1 DNA to cDNA expression microarray evidence
TMC1 YOR052C AN1-type zinc finger protein, effector of proteotoxic stress response regulation 1 1 1 DNA to cDNA expression microarray evidence
AGA1 YNR044W Anchorage subunit of a-agglutinin of a-cells regulation 1 1 1 DNA to cDNA expression microarray evidence
ALP1 YNL270C Arginine transporter regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARG4 YHR018C Argininosuccinate lyase regulation 1 1 1 DNA to cDNA expression microarray evidence
BAR1 YIL015W Aspartyl protease secreted to periplasmic space of mating type a cell regulation 1 1 1 DNA to cDNA expression microarray evidence
APL1 YJR005W Beta-adaptin regulation 1 1 1 DNA to cDNA expression microarray evidence
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase regulation 1 1 1 DNA to cDNA expression microarray evidence
CLB1 YGR108W B-type cyclin involved in cell cycle progression regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CMK2 YOL016C Calmodulin-dependent protein kinase regulation 1 1 1 DNA to cDNA expression microarray evidence
CWP1 YKL096W Cell wall mannoprotein that localizes to birth scars of daughter cells regulation 1 1 1 DNA to cDNA expression microarray evidence
YGP1 YNL160W Cell wall-related secretory glycoprotein regulation 1 1 1 DNA to cDNA expression microarray evidence
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity regulation 1 1 1 DNA to cDNA expression microarray evidence
ISU1 YPL135W Conserved protein of the mitochondrial matrix regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CWP2 YKL096W-A Covalently linked cell wall mannoprotein regulation 1 1 1 DNA to cDNA expression microarray evidence
CCC2 YDR270W Cu(+2)-transporting P-type ATPase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CIP1 YPL014W Cyclin-dependent kinase inhibitor regulation 1 1 1 DNA to cDNA expression microarray evidence
CYT1 YOR065W Cytochrome c1 regulation 1 1 1 DNA to cDNA expression microarray evidence
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family regulation 1 1 1 DNA to cDNA expression microarray evidence
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ALD6 YPL061W Cytosolic aldehyde dehydrogenase regulation 1 1 1 DNA to cDNA expression microarray evidence
ATX1 YNL259C Cytosolic copper metallochaperone regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YSR3 YKR053C Dihydrosphingosine 1-phosphate phosphatase regulation 1 1 1 DNA to cDNA expression microarray evidence
ILV3 YJR016C Dihydroxyacid dehydratase regulation 1 1 1 DNA to cDNA expression microarray evidence
HSP104 YLL026W Disaggregase regulation 1 1 1 DNA to cDNA expression microarray evidence
DDR48 YMR173W DNA damage-responsive protein regulation 1 1 1 DNA to cDNA expression microarray evidence
YOR225W YOR225W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YAL004W YAL004W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YDL023C YDL023C Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YDR154C YDR154C Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YMR173W-A YMR173W-A Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
LSP1 YPL004C Eisosome core component regulation 1 1 1 DNA to cDNA expression microarray evidence
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HMX1 YLR205C ER localized heme oxygenase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone regulation 1 1 1 DNA to cDNA expression microarray evidence
ENB1 YOL158C Ferric enterobactin transmembrane transporter regulation 1 1 1 DNA to cDNA expression microarray evidence
FRE4 YNR060W Ferric reductase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GLK1 YCL040W Glucokinase regulation 1 1 1 DNA to cDNA expression microarray evidence
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NCW2 YLR194C GPI-anchored protein involved in cell wall remodeling regulation 1 1 1 DNA to cDNA expression microarray evidence
CTR1 YPR124W High-affinity copper transporter of plasma membrane regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SSC1 YJR045C Hsp70 family ATPase regulation 1 1 1 DNA to cDNA expression microarray evidence
SSA2 YLL024C HSP70 family ATP-binding protein regulation 1 1 1 DNA to cDNA expression microarray evidence
HSP82 YPL240C Hsp90 chaperone regulation 1 1 1 DNA to cDNA expression microarray evidence
TSL1 YML100W Large subunit of trehalose 6-phosphate synthase/phosphatase complex regulation 1 1 1 DNA to cDNA expression microarray evidence
CAR2 YLR438W L-ornithine transaminase (OTAse) regulation 1 1 1 DNA to cDNA expression microarray evidence
LSM5 YER146W Lsm (Like Sm) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LYP1 YNL268W Lysine permease regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FIT2 YOR382W Mannoprotein that is incorporated into the cell wall regulation 1 1 1 DNA to cDNA expression microarray evidence
FIT1 YDR534C Mannoprotein that is incorporated into the cell wall regulation 1 1 1 DNA to cDNA expression microarray evidence
HOP2 YGL033W Meiosis-specific protein that localizes to chromosomes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPO20 YMR017W Meiosis-specific subunit of the t-SNARE complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IZH4 YOL101C Membrane protein involved in zinc ion homeostasis regulation 1 1 1 DNA to cDNA expression microarray evidence
NDE1 YMR145C Mitochondrial external NADH dehydrogenase regulation 1 1 1 DNA to cDNA expression microarray evidence
ARG7 YMR062C Mitochondrial ornithine acetyltransferase regulation 1 1 1 DNA to cDNA expression microarray evidence
OM14 YBR230C Mitochondrial outer membrane receptor for cytosolic ribosomes regulation 1 1 1 DNA to cDNA expression microarray evidence
MTM1 YGR257C Mitochondrial protein of the mitochondrial carrier family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ISU2 YOR226C Mitochondrial protein required for iron-sulfur protein synthesis regulation 1 1 1 DNA to cDNA expression microarray evidence
ARA2 YMR041C NAD-dependent arabinose dehydrogenase regulation 1 1 1 DNA to cDNA expression microarray evidence
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) regulation 1 1 1 DNA to cDNA expression microarray evidence
GPD1 YDL022W NAD-dependent glycerol-3-phosphate dehydrogenase regulation 1 1 1 DNA to cDNA expression microarray evidence
HSL1 YKL101W Nim1p-related protein kinase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
EHT1 YBR177C Octanoyl-CoA:ethanol acyltransferase regulation 1 1 1 DNA to cDNA expression microarray evidence
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin) regulation 1 1 1 DNA to cDNA expression microarray evidence
PRM4 YPL156C Pheromone-regulated protein proposed to be involved in mating regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RCR1 YBR005W Plasma membrane (PM) ubiquitin ligase-substrate adaptor regulation 1 1 1 DNA to cDNA expression microarray evidence
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin regulation 1 1 1 DNA to cDNA expression microarray evidence
TPO4 YOR273C Polyamine transporter of the major facilitator superfamily regulation 1 1 1 DNA to cDNA expression microarray evidence
RPN10 YHR200W Proteasome polyubiquitin receptor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SDS23 YGL056C Protein involved in cell separation during budding regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RCN2 YOR220W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
FHN1 YGR131W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
DIA1 YMR316W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
RFS1 YBR052C Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YMR316C-A YMR316C-A Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
AIM46 YHR199C Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AIM17 YHL021C Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
SUE1 YPR151C Protein required for degradation of unstable forms of cytochrome c regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MND1 YGL183C Protein required for recombination and meiotic nuclear division regulation 1 1 1 chromatin immunoprecipitation-chip evidence
KEL2 YGR238C Protein that negatively regulates mitotic exit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MRX18 YBR056W Putative glycoside hydrolase of the mitochondrial intermembrane space regulation 1 1 1 DNA to cDNA expression microarray evidence
FTH1 YBR207W Putative high affinity iron transporter regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ACO2 YJL200C Putative mitochondrial aconitase isozyme regulation 1 1 1 DNA to cDNA expression microarray evidence
YER079W YER079W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YKL097C YKL097C Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YOR385W YOR385W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YOR316C-A YOR316C-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YPL277C YPL277C Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YOL014W YOL014W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
TOS4 YLR183C Putative transcription factor, contains Forkhead Associated domain regulation 1 1 1 DNA to cDNA expression microarray evidence
YDR034C-D YDR034C-D Retrotransposon TYA Gag and TYB Pol genes regulation 1 1 1 DNA to cDNA expression microarray evidence
YMR051C YMR051C Retrotransposon TYA Gag gene co-transcribed with TYB Pol regulation 1 1 1 DNA to cDNA expression microarray evidence
RNR2 YJL026W Ribonucleotide-diphosphate reductase (RNR), small subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
LYS1 YIR034C Saccharopine dehydrogenase (NAD+, L-lysine-forming) regulation 1 1 1 DNA to cDNA expression microarray evidence
LYS9 YNR050C Saccharopine dehydrogenase (NADP+, L-glutamate-forming) regulation 1 1 1 DNA to cDNA expression microarray evidence
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) regulation 1 1 1 DNA to cDNA expression microarray evidence
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity regulation 1 1 1 DNA to cDNA expression microarray evidence
LAF1 YMR102C Sterol-binding beta-propeller protein regulation 1 1 1 DNA to cDNA expression microarray evidence
LTO1 YNL260C Substrate-specific adaptor protein involved in apo-Rli1p maturation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) regulation 1 1 1 DNA to cDNA expression microarray evidence
SDH3 YKL141W Subunit of succinate dehydrogenase and of TIM22 translocase regulation 1 1 1 DNA to cDNA expression microarray evidence
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
KGD1 YIL125W Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex regulation 1 1 1 DNA to cDNA expression microarray evidence
HSP60 YLR259C Tetradecameric mitochondrial chaperonin regulation 1 1 1 DNA to cDNA expression microarray evidence
PHD1 YKL043W Transcriptional activator that enhances pseudohyphal growth regulation 1 1 1 DNA to cDNA expression microarray evidence
MBF1 YOR298C-A Transcriptional coactivator regulation 1 1 1 DNA to cDNA expression microarray evidence
WTM1 YOR230W Transcriptional modulator regulation 1 1 1 DNA to cDNA expression microarray evidence
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARN2 YHL047C Transporter regulation 1 1 1 northern blot evidence
YDJ1 YNL064C Type I HSP40 co-chaperone regulation 1 1 1 DNA to cDNA expression microarray evidence
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p regulation 1 1 1 DNA to cDNA expression microarray evidence
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) regulation 1 1 1 DNA to cDNA expression microarray evidence
UGP1 YKL035W UDP-glucose pyrophosphorylase (UGPase) regulation 1 1 1 DNA to cDNA expression microarray evidence
VMR1 YHL035C Vacuolar membrane protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ZRT3 YKL175W Vacuolar membrane zinc transporter regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ATG42 YBR139W Vacuolar serine-type carboxypeptidase regulation 1 1 1 DNA to cDNA expression microarray evidence
COT1 YOR316C Vacuolar transporter that mediates zinc transport into the vacuole regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism genetic 1 1 1 Negative Genetic
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor physical 1 1 1 Two-hybrid
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Reconstituted Complex
CYC8 YBR112C General transcriptional co-repressor genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein physical 1 1 1 Two-hybrid
ZPR1 YGR211W Essential protein with two zinc fingers physical 1 1 1 Two-hybrid
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Protein-RNA
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway physical 1 1 1 Two-hybrid
SIT1 YEL065W Ferrioxamine B transporter genetic 1 1 1 Phenotypic Enhancement
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation physical 1 1 1 Affinity Capture-Western
CHL4 YDR254W Outer kinetochore protein required for chromosome stability physical 1 1 1 Affinity Capture-Western
MAC1 YMR021C Copper-sensing transcription factor physical 1 1 1 Affinity Capture-Western
NBP35 YGL091C Essential cytoplasmic iron-sulfur cluster binding protein physical 1 1 1 Two-hybrid
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Synthetic Rescue
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Phenotypic Suppression
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 Affinity Capture-Western
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Synthetic Rescue
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Dosage Rescue
CBF2 YGR140W Essential kinetochore protein genetic 1 1 1 Synthetic Growth Defect
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Synthetic Growth Defect
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Synthetic Growth Defect
SKP1 YDR328C Evolutionarily conserved kinetochore protein genetic 1 1 1 Synthetic Growth Defect
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Synthetic Rescue
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
RTS2 YOR077W Basic zinc-finger protein genetic 1 1 1 Negative Genetic
SUT2 YPR009W Zn2Cys6 family transcription factor genetic 1 1 1 Negative Genetic
MRP49 YKL167C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Dosage Growth Defect
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Synthetic Growth Defect
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Synthetic Growth Defect
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 1 1 1 Synthetic Growth Defect
SHU2 YDR078C Component of Shu complex (aka PCSS complex) genetic 1 1 1 Synthetic Growth Defect
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Synthetic Growth Defect
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Growth Defect
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Synthetic Growth Defect
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Synthetic Growth Defect
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Synthetic Growth Defect
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Synthetic Growth Defect
YPS3 YLR121C Aspartic protease genetic 1 1 1 Synthetic Growth Defect
SPO77 YLR341W Meiosis-specific protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SSH1 YBR283C Subunit of the Ssh1 translocon complex genetic 1 1 1 Synthetic Growth Defect
MIT1 YEL007W Transcriptional regulator of pseudohyphal growth genetic 1 1 1 Synthetic Growth Defect
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Synthetic Growth Defect
MNS1 YJR131W Alpha-1,2-mannosidase genetic 1 1 1 Synthetic Growth Defect
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Synthetic Growth Defect
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Synthetic Growth Defect
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Synthetic Lethality
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Synthetic Lethality
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Synthetic Lethality
REX4 YOL080C Putative RNA exonuclease genetic 1 1 1 Synthetic Lethality
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Synthetic Lethality
GDS1 YOR355W Protein involved in histone H4 acetylation at ribosomal protein genes genetic 1 1 1 Synthetic Lethality
FTR1 YER145C High affinity iron permease genetic 1 1 1 Dosage Growth Defect
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Dosage Growth Defect
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Dosage Growth Defect
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Dosage Growth Defect
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 1 1 1 Dosage Growth Defect
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Dosage Growth Defect
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Dosage Growth Defect
GEP4 YHR100C Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase) genetic 1 1 1 Dosage Growth Defect
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Dosage Growth Defect
CYT2 YKL087C Cytochrome c1 heme lyase genetic 1 1 1 Dosage Growth Defect
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Dosage Growth Defect
MRS2 YOR334W Mitochondrial inner membrane Mg(2+) channel genetic 1 1 1 Dosage Growth Defect
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Dosage Growth Defect
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Dosage Growth Defect
VPS36 YLR417W Component of the ESCRT-II complex genetic 1 1 1 Dosage Growth Defect
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Dosage Growth Defect
VPS3 YDR495C Component of CORVET membrane tethering complex genetic 1 1 1 Dosage Growth Defect
PEP12 YOR036W Target membrane receptor (t-SNARE) genetic 1 1 1 Dosage Growth Defect
MZM1 YDR493W Protein required for assembly of the cytochrome bc(1) complex genetic 1 1 1 Dosage Growth Defect
GEP7 YGL057C Protein of unknown function genetic 1 1 1 Dosage Growth Defect
MTC3 YGL226W Protein of unknown function genetic 1 1 1 Dosage Growth Defect
YJR120W YJR120W Protein of unknown function genetic 1 1 1 Dosage Growth Defect
RCF1 YML030W Cytochrome c oxidase subunit genetic 1 1 1 Dosage Growth Defect
BSC4 YNL269W Protein of unknown function genetic 1 1 1 Dosage Growth Defect
RCF2 YNR018W Cytochrome c oxidase subunit genetic 1 1 1 Dosage Growth Defect
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 1 1 1 Dosage Growth Defect
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Dosage Growth Defect
RIM11 YMR139W Protein kinase genetic 1 1 1 Dosage Growth Defect
SSQ1 YLR369W Mitochondrial hsp70-type molecular chaperone genetic 1 1 1 Synthetic Rescue
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Synthetic Growth Defect
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression genetic 1 1 1 Negative Genetic
MAL33 YBR297W MAL-activator protein genetic 1 1 1 Negative Genetic
HOT1 YMR172W Transcription factor for glycerol biosynthetic genes genetic 1 1 1 Negative Genetic
ZDS2 YML109W Protein with a role in regulating Swe1p-dependent polarized growth genetic 1 1 1 Negative Genetic
MDS3 YGL197W Putative component of the TOR regulatory pathway genetic 1 1 1 Negative Genetic
YOX1 YML027W Homeobox transcriptional repressor genetic 1 1 1 Negative Genetic
AKR2 YOR034C Ankyrin repeat-containing protein genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Negative Genetic
PUL4 YNR063W Putative zinc-cluster transcription factor genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth genetic 1 1 1 Negative Genetic
MGA1 YGR249W Protein similar to heat shock transcription factor genetic 1 1 1 Negative Genetic
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Negative Genetic
YHP1 YDR451C Homeobox transcriptional repressor genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
ECM23 YPL021W Non-essential protein of unconfirmed function genetic 1 1 1 Negative Genetic
SPS18 YNL204C Protein of unknown function, contains a putative zinc-binding domain genetic 1 1 1 Negative Genetic
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation genetic 1 1 1 Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Negative Genetic
IME4 YGL192W mRNA N6-adenosine methyltransferase genetic 1 1 1 Negative Genetic
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 1 1 1 Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
RME1 YGR044C Zinc finger protein involved in control of meiosis genetic 1 1 1 Negative Genetic
MSS11 YMR164C Transcription factor genetic 1 1 1 Negative Genetic
STB1 YNL309W Protein with role in regulation of MBF-specific transcription at Start genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Positive Genetic
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 1 1 1 Positive Genetic
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex genetic 1 1 1 Positive Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Negative Genetic
LEU3 YLR451W Zinc-knuckle transcription factor, repressor and activator genetic 1 1 1 Negative Genetic
CUP9 YPL177C Homeodomain-containing transcriptional repressor genetic 1 1 1 Negative Genetic
PLM2 YDR501W Putative transcription factor, contains Forkhead Associated domain genetic 1 1 1 Negative Genetic
RAD51 YER095W Strand exchange protein genetic 1 1 1 Positive Genetic
ROX1 YPR065W Heme-dependent repressor of hypoxic genes genetic 1 1 1 Positive Genetic
ERT1 YBR239C Transcriptional regulator genetic 1 1 1 Positive Genetic
MBP1 YDL056W Transcription factor genetic 1 1 1 Positive Genetic
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family genetic 1 1 1 Positive Genetic
LCB4 YOR171C Sphingoid long-chain base kinase genetic 1 1 1 Positive Genetic
COM2 YER130C Transcription factor that binds IME1 Upstream Activation Signal (UAS) genetic 1 1 1 Positive Genetic
ISR1 YPR106W Predicted protein kinase genetic 1 1 1 Positive Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Positive Genetic
PRR1 YKL116C Serine/threonine protein kinase genetic 1 1 1 Positive Genetic
CNA1 YLR433C Calcineurin A genetic 1 1 1 Positive Genetic
STB4 YMR019W Putative transcription factor genetic 1 1 1 Positive Genetic
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Positive Genetic
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Positive Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Positive Genetic
FPK1 YNR047W Ser/Thr protein kinase genetic 1 1 1 Positive Genetic
UPC2 YDR213W Sterol regulatory element binding protein genetic 1 1 1 Positive Genetic
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Positive Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Positive Genetic
OCA2 YNL056W Protein of unknown function genetic 1 1 1 Positive Genetic
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Positive Genetic
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Lethality
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Phenotypic Enhancement
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Negative Genetic
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
GEP5 YLR091W Protein of unknown function genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Positive Genetic
ELO3 YLR372W Elongase genetic 1 1 1 Negative Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Negative Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
MIP1 YOR330C Mitochondrial DNA polymerase gamma genetic 1 1 1 Negative Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Synthetic Lethality
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Synthetic Lethality
ECO1 YFR027W Acetyltransferase required for sister chromatid cohesion genetic 1 1 1 Synthetic Lethality
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Synthetic Growth Defect
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase genetic 1 1 1 Synthetic Lethality
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Synthetic Growth Defect
DRE2 YKR071C Component of the cytosolic Fe-S protein assembly (CIA) machinery genetic 1 1 1 Phenotypic Suppression
MMT1 YMR177W Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Synthetic Rescue
MMT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Synthetic Rescue
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Positive Genetic
MAK5 YBR142W Essential nucleolar protein genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
RLI1 YDR091C Essential Fe-S protein genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
UTP5 YDR398W Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Negative Genetic
SYF1 YDR416W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Negative Genetic
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 1 1 1 Negative Genetic
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly genetic 1 1 1 Negative Genetic
ERG27 YLR100W 3-keto sterol reductase genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Negative Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
RPO31 YOR116C RNA polymerase III largest subunit C160 genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Negative Genetic
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
PFF1 YBR074W Multi-spanning vacuolar membrane protease genetic 1 1 1 Negative Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
IMP21 YIL154C Transcriptional activator involved in maintenance of ion homeostasis genetic 1 1 1 Negative Genetic
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein genetic 1 1 1 Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
FRE1 YLR214W Ferric reductase and cupric reductase genetic 1 1 1 Negative Genetic
TSR2 YLR435W Protein with a potential role in pre-rRNA processing genetic 1 1 1 Negative Genetic
RPS18B YML026C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 1 1 1 Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Negative Genetic
CYB5 YNL111C Cytochrome b5 genetic 1 1 1 Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Negative Genetic
YPR003C YPR003C Putative sulfate permease genetic 1 1 1 Negative Genetic
TIP41 YPR040W Tap42p-interacting protein genetic 1 1 1 Negative Genetic
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Negative Genetic
TMH18 YPR098C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Synthetic Growth Defect
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Phenotypic Suppression
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
YPK1 YKL126W S/T protein kinase genetic 1 1 1 Synthetic Rescue
OSH3 YHR073W Member of an oxysterol-binding protein family genetic 1 1 1 Synthetic Rescue
TIS11 YLR136C mRNA-binding protein expressed during iron starvation genetic 1 1 1 Phenotypic Suppression
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Negative Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
CCC1 YLR220W Vacuolar Fe2+/Mn2+ transporter genetic 1 1 1 Synthetic Growth Defect
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
ADI1 YMR009W Acireductone dioxygenease involved in methionine salvage pathway genetic 1 1 1 Negative Genetic