Standard name Systematic name Name description Description
ROX1 YPR065W Heme-dependent repressor of hypoxic genes Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance
Visualize the interactome of ROX1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.104 NaN NaN
Nucleolus 0.107 0.062 0.072
Nucleus 0.930 0.955 0.904

GFP localization & abundance

GFP localization GFP abundance
nucleus 238

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ROX1 11 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RAD52 YML032C Protein involved in homologous recombination genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 4 3 3 Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Suppression
HYP2 YEL034W Translation elongation factor eIF-5A genetic 4 2 3 Positive Genetic, Positive Genetic, Synthetic Rescue, Synthetic Rescue
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 3 2 2 Dosage Lethality, Dosage Lethality, Positive Genetic
UTR5 YEL035C Protein of unknown function genetic 3 2 2 Positive Genetic, Synthetic Rescue, Synthetic Rescue
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane regulation 2 2 2 DNA to cDNA expression microarray evidence, northern blot evidence
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 2 2 Negative Genetic, Positive Genetic
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 2 1 2 Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 2 1 2 Negative Genetic, Negative Genetic
RAD18 YCR066W E3 ubiquitin ligase genetic 2 1 2 Negative Genetic, Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 2 1 2 Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 2 1 2 Negative Genetic, Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response genetic 2 1 2 Negative Genetic, Negative Genetic
ERG2 YMR202W C-8 sterol isomerase genetic 2 1 2 Negative Genetic, Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 2 1 2 Negative Genetic, Negative Genetic
SLX1 YBR228W Endonuclease involved in DNA recombination and repair genetic 2 1 2 Negative Genetic, Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 2 1 2 Negative Genetic, Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 2 1 2 Negative Genetic, Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 2 1 2 Negative Genetic, Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 2 1 2 Negative Genetic, Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 2 1 2 Negative Genetic, Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 2 1 2 Negative Genetic, Negative Genetic
COX10 YPL172C Heme A:farnesyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
AGA1 YNR044W Anchorage subunit of a-agglutinin of a-cells regulation 2 2 1 chromatin immunoprecipitation-qPCR evidence, northern blot evidence
RPB7 YDR404C RNA polymerase II subunit B16 genetic 2 2 1 Negative Genetic, Positive Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 2 1 1 Negative Genetic, Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSN4 YKL062W Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SKN7 YHR206W Nuclear response regulator and transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family regulation 1 1 1 RNA-sequencing evidence
SIR3 YLR442C Silencing protein regulation 1 1 1 RNA-sequencing evidence
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains regulation 1 1 1 RNA-sequencing evidence
GND2 YGR256W 6-phosphogluconate dehydrogenase (decarboxylating) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AKR2 YOR034C Ankyrin repeat-containing protein regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HMS1 YOR032C bHLH protein with similarity to myc-family transcription factors regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CMK2 YOL016C Calmodulin-dependent protein kinase regulation 1 1 1 DNA to cDNA expression microarray evidence
NCE103 YNL036W Carbonic anhydrase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TIR1 YER011W Cell wall mannoprotein regulation 1 1 1 northern blot evidence
DAN1 YJR150C Cell wall mannoprotein regulation 1 1 1 DNA to cDNA expression microarray evidence
LAC1 YKL008C Ceramide synthase component regulation 1 1 1 DNA to cDNA expression microarray evidence
HEM13 YDR044W Coproporphyrinogen III oxidase regulation 1 1 1 DNA to cDNA expression microarray evidence
DUG1 YFR044C Cys-Gly metallo-di-peptidase regulation 1 1 1 DNA to cDNA expression microarray evidence
CYB5 YNL111C Cytochrome b5 regulation 1 1 1 DNA to cDNA expression microarray evidence
CYC3 YAL039C Cytochrome c heme lyase (holocytochrome c synthase) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYC1 YJR048W Cytochrome c, isoform 1 regulation 1 1 1 DNA to cDNA expression microarray evidence
LIA1 YJR070C Deoxyhypusine hydroxylase regulation 1 1 1 DNA to cDNA expression microarray evidence
DJP1 YIR004W ER-associated chaperone involved in protein targeting regulation 1 1 1 DNA to cDNA expression microarray evidence
YPR063C YPR063C ER-localized protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MAK16 YAL025C Essential nuclear protein regulation 1 1 1 DNA to cDNA expression microarray evidence
LCP5 YER127W Essential protein involved in maturation of 18S rRNA regulation 1 1 1 DNA to cDNA expression microarray evidence
TAP42 YMR028W Essential protein involved in the TOR signaling pathway regulation 1 1 1 DNA to cDNA expression microarray evidence
ENB1 YOL158C Ferric enterobactin transmembrane transporter regulation 1 1 1 DNA to cDNA expression microarray evidence
SIT1 YEL065W Ferrioxamine B transporter regulation 1 1 1 DNA to cDNA expression microarray evidence
FET3 YMR058W Ferro-O2-oxidoreductase regulation 1 1 1 DNA to cDNA expression microarray evidence
COQ6 YGR255C Flavin-dependent monooxygenase involved in ubiquinone biosynthesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPI1 YER150W GPI-anchored cell wall protein involved in weak acid resistance regulation 1 1 1 DNA to cDNA expression microarray evidence
ROX1 YPR065W Heme-dependent repressor of hypoxic genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FTR1 YER145C High affinity iron permease regulation 1 1 1 DNA to cDNA expression microarray evidence
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane regulation 1 1 1 DNA to cDNA expression microarray evidence
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SED1 YDR077W Major stress-induced structural GPI-cell wall glycoprotein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FIT2 YOR382W Mannoprotein that is incorporated into the cell wall regulation 1 1 1 DNA to cDNA expression microarray evidence
FIT3 YOR383C Mannoprotein that is incorporated into the cell wall regulation 1 1 1 DNA to cDNA expression microarray evidence
FUS1 YCL027W Membrane protein localized to the shmoo tip regulation 1 1 1 northern blot evidence
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator regulation 1 1 1 DNA to cDNA expression microarray evidence
SCM4 YGR049W Mitochondrial outer membrane protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex regulation 1 1 1 DNA to cDNA expression microarray evidence
AMN1 YBR158W Modulator of cell separation and mitotic exit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YBL029W YBL029W Non-essential protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FYV7 YLR068W Nucleolar protein required for maturation of 18S rRNA regulation 1 1 1 DNA to cDNA expression microarray evidence
PMA1 YGL008C Plasma membrane P2-type H+-ATPase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ATO3 YDR384C Plasma membrane protein, putative ammonium transporter regulation 1 1 1 northern blot evidence
GAT2 YMR136W Protein containing GATA family zinc finger motifs regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YBL029C-A YBL029C-A Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DIA1 YMR316W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
ECL1 YGR146C Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ICS2 YBR157C Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YOR032W-A YOR032W-A Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YMR315W YMR315W Protein with NADP(H) oxidoreductase activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TIR2 YOR010C Putative cell wall mannoprotein regulation 1 1 1 DNA to cDNA expression microarray evidence
YGR146C-A YGR146C-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RRT15 YLR162W-A Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YGL007C-A YGL007C-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YGL006W-A YGL006W-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
VPS63 YLR261C Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
CMR3 YPR013C Putative zinc finger protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC19 YAL038W Pyruvate kinase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GAC1 YOR178C Regulatory subunit for Glc7p type-1 protein phosphatase (PP1) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
HUG1 YML058W-A Ribonucleotide reductase inhibitor regulation 1 1 1 DNA to cDNA expression microarray evidence
SUR2 YDR297W Sphinganine C4-hydroxylase regulation 1 1 1 DNA to cDNA expression microarray evidence
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling regulation 1 1 1 DNA to cDNA expression microarray evidence
ERG1 YGR175C Squalene epoxidase regulation 1 1 1 DNA to cDNA expression microarray evidence
GID8 YMR135C Subunit of GID Complex, binds strongly to central component Vid30p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COX5B YIL111W Subunit Vb of cytochrome c oxidase regulation 1 1 1 DNA to cDNA expression microarray evidence
VHR1 YIL056W Transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHD1 YKL043W Transcriptional activator that enhances pseudohyphal growth regulation 1 1 1 northern blot evidence
HAP4 YKL109W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ANB1 YJR047C Translation elongation factor eIF-5A regulation 1 1 1 DNA to cDNA expression microarray evidence
PMC1 YGL006W Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions regulation 1 1 1 chromatin immunoprecipitation-chip evidence
VRP1 YLR337C Verprolin, proline-rich actin-associated protein regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Positive Genetic
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Positive Genetic
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly genetic 1 1 1 Negative Genetic
POP5 YAL033W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
MFT1 YML062C Subunit of the THO complex genetic 1 1 1 Negative Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing genetic 1 1 1 Negative Genetic
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b genetic 1 1 1 Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Positive Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Phenotypic Suppression
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase genetic 1 1 1 Negative Genetic
MAS1 YLR163C Beta subunit of the mitochondrial processing protease (MPP) genetic 1 1 1 Synthetic Growth Defect
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
RAD51 YER095W Strand exchange protein genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
DUG1 YFR044C Cys-Gly metallo-di-peptidase genetic 1 1 1 Negative Genetic
HOS4 YIL112W Subunit of the Set3 complex genetic 1 1 1 Positive Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
HEM13 YDR044W Coproporphyrinogen III oxidase genetic 1 1 1 Positive Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Positive Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Positive Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane genetic 1 1 1 Phenotypic Suppression
PYC2 YBR218C Pyruvate carboxylase isoform genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Phenotypic Suppression
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Phenotypic Suppression
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 1 1 1 Positive Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Negative Genetic
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Negative Genetic
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Positive Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Negative Genetic
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Negative Genetic
CDC43 YGL155W Beta subunit of geranylgeranyltransferase type I genetic 1 1 1 Negative Genetic
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Positive Genetic
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 1 1 1 Negative Genetic
CSM3 YMR048W Replication fork associated factor genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Positive Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
NIS1 YNL078W Protein involved in axial bud site selection genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
CST9 YLR394W SUMO E3 ligase genetic 1 1 1 Negative Genetic
HAP1 YLR256W Zinc finger transcription factor genetic 1 1 1 Phenotypic Suppression
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Negative Genetic
HAP4 YKL109W Transcription factor genetic 1 1 1 Phenotypic Suppression
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 1 1 1 Negative Genetic
BPT1 YLL015W ABC type transmembrane transporter of MRP/CFTR family genetic 1 1 1 Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Positive Genetic
ERV29 YGR284C Protein localized to COPII-coated vesicles genetic 1 1 1 Negative Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Negative Genetic
NOP8 YOL144W Nucleolar protein required for 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Phenotypic Enhancement
QDR3 YBR043C Multidrug transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
AIM22 YJL046W Lipoate-protein ligase genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
CBS1 YDL069C Mitochondrial translational activator of the COB mRNA genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites genetic 1 1 1 Negative Genetic
TAF2 YCR042C TFIID subunit (150 kDa) physical 1 1 1 Affinity Capture-MS
SEN54 YPL083C Subunit of the tRNA splicing endonuclease physical 1 1 1 PCA
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-RNA
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
TED1 YIL039W GPI-glycan remodelase genetic 1 1 1 Phenotypic Suppression
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Negative Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Negative Genetic
YFR057W YFR057W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Negative Genetic
STB1 YNL309W Protein with role in regulation of MBF-specific transcription at Start genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
SCM3 YDL139C Nonhistone component of centromeric chromatin genetic 1 1 1 Negative Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
YBR221W-A YBR221W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YDR042C YDR042C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
YLR464W YLR464W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YMR230W-A YMR230W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RRG9 YNL213C Protein of unknown function genetic 1 1 1 Negative Genetic
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 1 1 1 Negative Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
RPS0A YGR214W Ribosomal 40S subunit protein S0A genetic 1 1 1 Negative Genetic
RPS1B YML063W Ribosomal protein of the small (40S) subunit genetic 1 1 1 Negative Genetic
YDR391C YDR391C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SLP1 YOR154W Glycosylated integral ER membrane protein of unknown function genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Positive Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Positive Genetic
STE6 YKL209C Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Rescue
HEM12 YDR047W Uroporphyrinogen decarboxylase genetic 1 1 1 Negative Genetic
KRE28 YDR532C Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
ICS2 YBR157C Protein of unknown function genetic 1 1 1 Negative Genetic
CYC1 YJR048W Cytochrome c, isoform 1 genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Positive Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 1 1 1 Negative Genetic
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Negative Genetic
PDR3 YBL005W Transcriptional activator of the pleiotropic drug resistance network genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
HAL9 YOL089C Putative transcription factor containing a zinc finger genetic 1 1 1 Negative Genetic
CCW14 YLR390W-A Covalently linked cell wall glycoprotein genetic 1 1 1 Negative Genetic
DFG10 YIL049W Probable polyprenol reductase genetic 1 1 1 Positive Genetic
AIM14 YGL160W NADPH oxidase localized to the perinuclear ER genetic 1 1 1 Negative Genetic
CRS5 YOR031W Copper-binding metallothionein genetic 1 1 1 Negative Genetic
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Positive Genetic
ICY1 YMR195W Protein of unknown function genetic 1 1 1 Negative Genetic
DCV1 YFR012W Protein of unknown function genetic 1 1 1 Negative Genetic
DAL1 YIR027C Allantoinase genetic 1 1 1 Negative Genetic
DBR1 YKL149C RNA lariat debranching enzyme genetic 1 1 1 Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Negative Genetic
OXR1 YPL196W Protein involved in regulation of vacuolar V-ATPase genetic 1 1 1 Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Negative Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
PAU14 YIL176C Protein of unknown function genetic 1 1 1 Negative Genetic