Standard name Systematic name Name description Description
HAP1 YLR256W Zinc finger transcription factor Zinc finger transcription factor; involved in the complex regulation of gene expression in response to levels of heme and oxygen; localizes to the mitochondrion as well as to the nucleus; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus
Visualize the interactome of HAP1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HAP1 4 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
HSP82 YPL240C Hsp90 chaperone physical 3 2 3 Reconstituted Complex, Reconstituted Complex, Two-hybrid
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
HAP1 YLR256W Zinc finger transcription factor physical 2 1 2 Reconstituted Complex, Reconstituted Complex
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression regulation 1 1 1 DNA to cDNA expression microarray evidence
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LEU3 YLR451W Zinc-knuckle transcription factor, repressor and activator regulation 1 1 1 DNA to cDNA expression microarray evidence
ERG10 YPL028W Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ACS2 YLR153C Acetyl-coA synthetase isoform regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ADO1 YJR105W Adenosine kinase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAM2 YKL019W Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SAR1 YPL218W ARF family GTPase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FAS1 YKL182W Beta subunit of fatty acid synthetase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ERG5 YMR015C C-22 sterol desaturase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ERG26 YGL001C C-3 sterol dehydrogenase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ERG25 YGR060W C-4 methyl sterol oxidase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ERG2 YMR202W C-8 sterol isomerase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CCW12 YLR110C Cell wall mannoprotein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COR1 YBL045C Core subunit of the ubiquinol-cytochrome c reductase complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CWP2 YKL096W-A Covalently linked cell wall mannoprotein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYB2 YML054C Cytochrome b2 (L-lactate cytochrome-c oxidoreductase) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYB5 YNL111C Cytochrome b5 regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYT1 YOR065W Cytochrome c1 regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYC1 YJR048W Cytochrome c, isoform 1 regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYC7 YEL039C Cytochrome c isoform 2, expressed under hypoxic conditions regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
OLE1 YGL055W Delta(9) fatty acid desaturase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ERG28 YER044C Endoplasmic reticulum membrane protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HMX1 YLR205C ER localized heme oxygenase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT23 YKL020C ER membrane protein involved in regulation of OLE1 transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FRE4 YNR060W Ferric reductase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FET3 YMR058W Ferro-O2-oxidoreductase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RGT1 YKL038W Glucose-responsive transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COX15 YER141W Heme a synthase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HMG1 YML075C HMG-CoA reductase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LYS4 YDR234W Homoaconitase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ERG11 YHR007C Lanosterol 14-alpha-demethylase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FAA1 YOR317W Long chain fatty acyl-CoA synthetase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CLD1 YGR110W Mitochondrial cardiolipin-specific phospholipase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NDE1 YMR145C Mitochondrial external NADH dehydrogenase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AAC1 YMR056C Mitochondrial inner membrane ADP/ATP translocator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SCM4 YGR049W Mitochondrial outer membrane protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PLN1 YKR046C Perilipin, involved in formation and stability of lipid droplets regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PDR16 YNL231C Phosphatidylinositol transfer protein (PITP) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ERG8 YMR220W Phosphomevalonate kinase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PUT4 YOR348C Proline permease regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SDS23 YGL056C Protein involved in cell separation during budding regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YHR050W-A YHR050W-A Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUE1 YPR151C Protein required for degradation of unstable forms of cytochrome c regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PTH4 YOL114C Protein similar to the human peptidyl-tRNA hydrolase gene ICT1 regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFK1 YKL051W Protein that regulates phospholipid asymmetry at plasma membrane regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UTR4 YEL038W Protein with sequence similarity to acireductone synthases regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CIR2 YOR356W Putative ortholog of human ETF-dH regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YML054C-A YML054C-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YHR007C-A YHR007C-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YOR316C-A YOR316C-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YKL096C-B YKL096C-B Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YBL044W YBL044W Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RTN1 YDR233C Reticulon protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COX4 YGL187C Subunit IV of cytochrome c oxidase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COX13 YGL191W Subunit VIa of cytochrome c oxidase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COX8 YLR395C Subunit VIII of cytochrome c oxidase (Complex IV) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COX7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TSA1 YML028W Thioredoxin peroxidase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ANB1 YJR047C Translation elongation factor eIF-5A regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UBX6 YJL048C UBX (ubiquitin regulatory X) domain-containing protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COT1 YOR316C Vacuolar transporter that mediates zinc transport into the vacuole regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BMH1 YER177W 14-3-3 protein, major isoform physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles genetic 1 1 1 Negative Genetic
CMK1 YFR014C Calmodulin-dependent protein kinase genetic 1 1 1 Positive Genetic
ATG12 YBR217W Ubiquitin-like modifier involved in autophagy and the Cvt pathway genetic 1 1 1 Negative Genetic
ERG20 YJL167W Farnesyl pyrophosphate synthetase physical 1 1 1 Two-hybrid
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 1 1 1 Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
AIR1 YIL079C Zinc knuckle protein genetic 1 1 1 Negative Genetic
ADE2 YOR128C Phosphoribosylaminoimidazole carboxylase genetic 1 1 1 Phenotypic Enhancement
ADY3 YDL239C Protein required for spore wall formation genetic 1 1 1 Negative Genetic
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 1 1 1 Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-Western
YDJ1 YNL064C Type I HSP40 co-chaperone physical 1 1 1 Affinity Capture-Western
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
YAK1 YJL141C Serine-threonine protein kinase physical 1 1 1 Affinity Capture-MS
SIZ1 YDR409W SUMO E3 ligase physical 1 1 1 Affinity Capture-MS
PDR10 YOR328W ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
YOL075C YOL075C Putative ABC transporter physical 1 1 1 PCA
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation physical 1 1 1 Affinity Capture-MS
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SET4 YJL105W Chromatin-associated protein involved in control of stress response physical 1 1 1 Affinity Capture-MS
UPC2 YDR213W Sterol regulatory element binding protein genetic 1 1 1 Synthetic Lethality
YND1 YER005W Apyrase with wide substrate specificity genetic 1 1 1 Synthetic Rescue
TPA1 YER049W Prolyl hydroxylase genetic 1 1 1 Synthetic Rescue
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Synthetic Rescue
RPN9 YDR427W Non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Synthetic Rescue
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Rescue
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Positive Genetic
SCS22 YBL091C-A Protein involved in regulation of phospholipid metabolism genetic 1 1 1 Positive Genetic
PYC2 YBR218C Pyruvate carboxylase isoform genetic 1 1 1 Positive Genetic
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Negative Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 1 1 1 Negative Genetic
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Negative Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
SMP3 YOR149C Alpha 1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
PFF1 YBR074W Multi-spanning vacuolar membrane protease genetic 1 1 1 Negative Genetic
RTC2 YBR147W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Negative Genetic
PSP1 YDR505C Asn and gln rich protein of unknown function genetic 1 1 1 Negative Genetic
YRB30 YGL164C RanGTP-binding protein genetic 1 1 1 Negative Genetic
MGA1 YGR249W Protein similar to heat shock transcription factor genetic 1 1 1 Negative Genetic
QCR10 YHR001W-A Subunit of the ubiqunol-cytochrome c oxidoreductase complex genetic 1 1 1 Negative Genetic
PFS1 YHR185C Sporulation protein required for prospore membrane formation genetic 1 1 1 Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TAG1 YLR173W Vacuolar membrane protein involved in termination of autophagy genetic 1 1 1 Negative Genetic
ROX1 YPR065W Heme-dependent repressor of hypoxic genes genetic 1 1 1 Phenotypic Suppression
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
GDA1 YEL042W Guanosine diphosphatase located in the Golgi genetic 1 1 1 Synthetic Rescue
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
ECM22 YLR228C Sterol regulatory element binding protein genetic 1 1 1 Synthetic Lethality