RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
physical |
17 |
6 |
12 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, PCA, Affinity Capture-MS, PCA, PCA, Co-localization, Affinity Capture-MS, Affinity Capture-MS |
HOT1 |
YMR172W |
Transcription factor for glycerol biosynthetic genes |
physical |
10 |
5 |
7 |
Two-hybrid, Two-hybrid, Biochemical Activity, Affinity Capture-MS, Co-localization, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Co-localization, Affinity Capture-MS |
FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
9 |
6 |
7 |
Synthetic Lethality, Synthetic Rescue, Dosage Rescue, Synthetic Rescue, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement, Synthetic Rescue, Dosage Rescue |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
physical |
9 |
5 |
7 |
Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, PCA, PCA, Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Affinity Capture-Western |
SKO1 |
YNL167C |
Basic leucine zipper transcription factor of the ATF/CREB family |
physical |
7 |
5 |
5 |
Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, PCA, Co-localization, Co-localization |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
7 |
4 |
5 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Biochemical Activity, Affinity Capture-MS, Biochemical Activity |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
7 |
2 |
5 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
7 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
6 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
6 |
5 |
5 |
Phenotypic Enhancement, Synthetic Rescue, Synthetic Growth Defect, Dosage Rescue, Phenotypic Suppression, Synthetic Growth Defect |
CYC8 |
YBR112C |
General transcriptional co-repressor |
genetic |
6 |
2 |
5 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
PTP2 |
YOR208W |
Phosphotyrosine-specific phosphatase |
physical |
6 |
2 |
5 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western |
NUP2 |
YLR335W |
Nucleoporin involved in nucleocytoplasmic transport |
physical |
6 |
5 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Co-localization, Affinity Capture-MS, Proximity Label-MS |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
6 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
6 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RGA1 |
YOR127W |
GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) |
genetic |
6 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
5 |
3 |
5 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments |
KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
genetic |
5 |
3 |
5 |
Synthetic Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression |
SKO1 |
YNL167C |
Basic leucine zipper transcription factor of the ATF/CREB family |
genetic |
5 |
1 |
5 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
5 |
3 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Dosage Rescue, Synthetic Growth Defect |
PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
physical |
5 |
4 |
3 |
Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, Biochemical Activity |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
physical |
5 |
4 |
2 |
Affinity Capture-Western, Two-hybrid, Biochemical Activity, Affinity Capture-Western, PCA |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
physical |
5 |
3 |
2 |
Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Biochemical Activity |
RGC1 |
YPR115W |
Putative regulator of the Fps1p glycerol channel |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Two-hybrid, Co-localization, Affinity Capture-MS |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
4 |
2 |
4 |
Biochemical Activity, Biochemical Activity, Biochemical Activity, Affinity Capture-MS |
CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
4 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
physical |
4 |
4 |
3 |
Affinity Capture-MS, Biochemical Activity, Two-hybrid, Co-localization |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Positive Genetic |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
genetic |
4 |
2 |
3 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Synthetic Rescue |
NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SIS2 |
YKR072C |
Negative regulatory subunit of protein phosphatase 1 (Ppz1p) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
YBR238C |
YBR238C |
Mitochondrial membrane protein |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
KIC1 |
YHR102W |
Protein kinase of the PAK/Ste20 family, required for cell integrity |
physical |
3 |
3 |
3 |
PCA, Affinity Capture-MS, Proximity Label-MS |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
physical |
3 |
3 |
3 |
Biochemical Activity, Affinity Capture-MS, Proximity Label-MS |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
3 |
3 |
3 |
Synthetic Rescue, Dosage Lethality, Positive Genetic |
MSB2 |
YGR014W |
Mucin family member involved in various signaling pathways |
genetic |
3 |
3 |
3 |
Synthetic Rescue, Phenotypic Suppression, Dosage Growth Defect |
CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
3 |
3 |
3 |
Synthetic Growth Defect, Dosage Growth Defect, Negative Genetic |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
3 |
3 |
3 |
Phenotypic Enhancement, Phenotypic Suppression, Negative Genetic |
CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
genetic |
3 |
2 |
3 |
Dosage Rescue, Phenotypic Suppression, Dosage Rescue |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue |
PTP3 |
YER075C |
Phosphotyrosine-specific protein phosphatase |
physical |
3 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression |
SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
genetic |
3 |
2 |
3 |
Phenotypic Suppression, Phenotypic Suppression, Dosage Growth Defect |
ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
PTP2 |
YOR208W |
Phosphotyrosine-specific phosphatase |
genetic |
3 |
1 |
3 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RML2 |
YEL050C |
Mitochondrial ribosomal protein of the large subunit (L2) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
PXP1 |
YEL020C |
Peroxisomal matrix protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEC9 |
YGR009C |
t-SNARE protein required for secretory vesicle-plasma membrane fusion |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
NKP2 |
YLR315W |
Central kinetochore protein and subunit of the Ctf19 complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
KRE1 |
YNL322C |
Cell wall glycoprotein involved in beta-glucan assembly |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CET1 |
YPL228W |
RNA 5'-triphosphatase involved in mRNA 5' capping |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
3 |
3 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic |
AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
3 |
3 |
2 |
Synthetic Growth Defect, Dosage Rescue, Negative Genetic |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Dosage Growth Defect |
GPD1 |
YDL022W |
NAD-dependent glycerol-3-phosphate dehydrogenase |
genetic |
3 |
2 |
2 |
Dosage Rescue, Synthetic Growth Defect, Synthetic Growth Defect |
YPD1 |
YDL235C |
Osmotic stress-responsive phosphorelay intermediate sensor protein |
genetic |
3 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
SMP1 |
YBR182C |
MADS-box transcription factor involved in osmotic stress response |
physical |
3 |
3 |
1 |
Affinity Capture-Western, Two-hybrid, Biochemical Activity |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
physical |
3 |
3 |
1 |
Co-localization, Affinity Capture-Western, Biochemical Activity |
STL1 |
YDR536W |
Glycerol proton symporter of the plasma membrane |
genetic |
3 |
3 |
1 |
Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
3 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity |
NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
3 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Growth Defect |
RCK1 |
YGL158W |
Protein kinase involved in oxidative stress response |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Biochemical Activity |
SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Co-localization |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
physical |
2 |
2 |
2 |
Biochemical Activity, Co-localization |
SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
physical |
2 |
2 |
2 |
Biochemical Activity, Co-localization |
SGD1 |
YLR336C |
Essential nuclear protein |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Lethality |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Synthetic Rescue |
TEC1 |
YBR083W |
Transcription factor targeting filamentation genes and Ty1 expression |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Suppression |
TCO89 |
YPL180W |
Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Suppression |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
SCO1 |
YBR037C |
Copper-binding protein of mitochondrial inner membrane |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
ISC1 |
YER019W |
Inositol phosphosphingolipid phospholipase C |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
STE4 |
YOR212W |
G protein beta subunit |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Dosage Growth Defect |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Dosage Growth Defect |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CNB1 |
YKL190W |
Calcineurin B |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
CBK1 |
YNL161W |
Serine/threonine protein kinase of the the RAM signaling network |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PTP3 |
YER075C |
Phosphotyrosine-specific protein phosphatase |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
STE7 |
YDL159W |
Signal transducing MAP kinase kinase |
genetic |
2 |
1 |
2 |
Phenotypic Suppression, Phenotypic Suppression |
STE11 |
YLR362W |
Signal transducing MEK kinase |
genetic |
2 |
1 |
2 |
Phenotypic Suppression, Phenotypic Suppression |
SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
SLN1 |
YIL147C |
Transmembrane histidine phosphotransfer kinase and osmosensor |
genetic |
2 |
1 |
2 |
Phenotypic Suppression, Phenotypic Suppression |
POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLU7 |
YDR088C |
RNA splicing factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TKL1 |
YPR074C |
Transketolase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
regulation |
2 |
2 |
1 |
mass spectrometry evidence, physical interaction evidence |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
regulation |
2 |
2 |
1 |
mass spectrometry evidence, physical interaction evidence |
SOG2 |
YOR353C |
Key component of the RAM signaling network |
regulation |
2 |
2 |
1 |
mass spectrometry evidence, physical interaction evidence |
KIC1 |
YHR102W |
Protein kinase of the PAK/Ste20 family, required for cell integrity |
regulation |
2 |
2 |
1 |
mass spectrometry evidence, physical interaction evidence |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
regulation |
2 |
2 |
1 |
mass spectrometry evidence, physical interaction evidence |
SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
regulation |
2 |
2 |
1 |
protein kinase assay evidence, qualitative western immunoblotting evidence |
YSP2 |
YDR326C |
Sterol-binding protein |
regulation |
2 |
2 |
1 |
mass spectrometry evidence, physical interaction evidence |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
regulation |
2 |
2 |
1 |
mass spectrometry evidence, physical interaction evidence |
UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
regulation |
2 |
2 |
1 |
mass spectrometry evidence, physical interaction evidence |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
regulation |
2 |
2 |
1 |
green fluorescent protein immunolocalization evidence, qualitative western immunoblotting evidence |
SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
regulation |
2 |
2 |
1 |
green fluorescent protein immunolocalization evidence, qualitative western immunoblotting evidence |
TOK1 |
YJL093C |
Outward-rectifier potassium channel of the plasma membrane |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Biochemical Activity |
NHA1 |
YLR138W |
Na+/H+ antiporter |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Biochemical Activity |
HSL1 |
YKL101W |
Nim1p-related protein kinase |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Biochemical Activity |
STE7 |
YDL159W |
Signal transducing MAP kinase kinase |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
physical |
2 |
2 |
1 |
Co-localization, Affinity Capture-Western |
WHI5 |
YOR083W |
Repressor of G1 transcription |
physical |
2 |
2 |
1 |
Biochemical Activity, Affinity Capture-Western |
MSA1 |
YOR066W |
Activator of G1-specific transcription factors MBF and SBF |
physical |
2 |
2 |
1 |
Biochemical Activity, Affinity Capture-Western |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Synthetic Growth Defect |
VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Phenotypic Enhancement |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
SIZ1 |
YDR409W |
SUMO E3 ligase |
genetic |
2 |
2 |
1 |
Dosage Growth Defect, Phenotypic Suppression |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Dosage Rescue |
KIN2 |
YLR096W |
S/T protein kinase |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Growth Defect |
KIN1 |
YDR122W |
S/T protein kinase |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Growth Defect |
NAB6 |
YML117W |
Putative RNA-binding protein |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Growth Defect |
AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
physical |
2 |
2 |
1 |
Biochemical Activity, Affinity Capture-Western |
EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SOV1 |
YMR066W |
Mitochondrial protein of unknown function |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GRE2 |
YOL151W |
3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase |
regulation |
1 |
1 |
1 |
northern blot evidence |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
regulation |
1 |
1 |
1 |
mass spectrometry evidence |
SKO1 |
YNL167C |
Basic leucine zipper transcription factor of the ATF/CREB family |
regulation |
1 |
1 |
1 |
electrophoretic mobility shift assay evidence |
STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
regulation |
1 |
1 |
1 |
mass spectrometry evidence |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
regulation |
1 |
1 |
1 |
mass spectrometry evidence |
NET1 |
YJL076W |
Core subunit of the RENT complex |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
CIP1 |
YPL014W |
Cyclin-dependent kinase inhibitor |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
ALD3 |
YMR169C |
Cytoplasmic aldehyde dehydrogenase |
regulation |
1 |
1 |
1 |
northern blot evidence |
CTT1 |
YGR088W |
Cytosolic catalase T |
regulation |
1 |
1 |
1 |
northern blot evidence |
STL1 |
YDR536W |
Glycerol proton symporter of the plasma membrane |
regulation |
1 |
1 |
1 |
northern blot evidence |
MFB1 |
YDR219C |
Mitochondria-associated F-box protein |
regulation |
1 |
1 |
1 |
mass spectrometry evidence |
NUP2 |
YLR335W |
Nucleoporin involved in nucleocytoplasmic transport |
regulation |
1 |
1 |
1 |
physical interaction evidence |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
regulation |
1 |
1 |
1 |
physical interaction evidence |
FAR8 |
YMR029C |
Protein involved in recovery from arrest in response to pheromone |
regulation |
1 |
1 |
1 |
mass spectrometry evidence |
PMD1 |
YER132C |
Protein with an N-terminal kelch-like domain |
regulation |
1 |
1 |
1 |
mass spectrometry evidence |
SAP1 |
YER047C |
Putative ATPase of the AAA family |
regulation |
1 |
1 |
1 |
mass spectrometry evidence |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
PKH1 |
YDR490C |
Serine/threonine protein kinase |
regulation |
1 |
1 |
1 |
mass spectrometry evidence |
SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
TFG1 |
YGR186W |
TFIIF (Transcription Factor II) largest subunit |
regulation |
1 |
1 |
1 |
mass spectrometry evidence |
ARR1 |
YPR199C |
Transcriptional activator of the basic leucine zipper (bZIP) family |
regulation |
1 |
1 |
1 |
electrophoretic mobility shift assay evidence |
AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
HAP1 |
YLR256W |
Zinc finger transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
regulation |
1 |
1 |
1 |
green fluorescent protein immunolocalization evidence |
SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
regulation |
1 |
1 |
1 |
green fluorescent protein immunolocalization evidence |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
regulation |
1 |
1 |
1 |
phosphatase assay evidence |
SSK22 |
YCR073C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
regulation |
1 |
1 |
1 |
green fluorescent protein immunolocalization evidence |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ESF1 |
YDR365C |
Nucleolar protein involved in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
AMN1 |
YBR158W |
Modulator of cell separation and mitotic exit |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
CDC42 |
YLR229C |
Small rho-like GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GAR1 |
YHR089C |
Protein component of the H/ACA snoRNP pseudouridylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARO1 |
YDR127W |
Pentafunctional arom protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BAT1 |
YHR208W |
Mitochondrial branched-chain amino acid (BCAA) aminotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BDF1 |
YLR399C |
BET family transcriptional regulator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM21 |
YIR003W |
Subunit of a complex that associates with actin filaments |
physical |
1 |
1 |
1 |
Co-localization |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
1 |
1 |
1 |
Biochemical Activity |
BOI2 |
YER114C |
Protein involved in polar growth |
physical |
1 |
1 |
1 |
Co-localization |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC45 |
YLR103C |
DNA replication initiation factor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIP1 |
YPL014W |
Cyclin-dependent kinase inhibitor |
physical |
1 |
1 |
1 |
Biochemical Activity |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYR1 |
YJL005W |
Adenylate cyclase |
physical |
1 |
1 |
1 |
Co-localization |
DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
DPB2 |
YPR175W |
Second largest subunit of DNA polymerase II (DNA polymerase epsilon) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EMP24 |
YGL200C |
Component of the p24 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN2 |
YDR283C |
Protein kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLY1 |
YEL046C |
Threonine aldolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
HIS4 |
YCL030C |
Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Co-localization |
GFA1 |
YKL104C |
Glutamine-fructose-6-phosphate amidotransferase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
GLT1 |
YDL171C |
NAD(+)-dependent glutamate synthase (GOGAT) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Co-localization |
ADA2 |
YDR448W |
Transcription coactivator |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CMD1 |
YBR109C |
Calmodulin |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ABF2 |
YMR072W |
Mitochondrial DNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BGL2 |
YGR282C |
Endo-beta-1,3-glucanase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AVT4 |
YNL101W |
Vacuolar transporter |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
GAL83 |
YER027C |
One of three alternate beta-subunits of the Snf1 kinase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CAM1 |
YPL048W |
One of two isoforms of the gamma subunit of eEF1B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
physical |
1 |
1 |
1 |
Co-localization |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
BOI1 |
YBL085W |
Protein involved in polar growth, functionally redundant with Boi2p |
physical |
1 |
1 |
1 |
Co-localization |
DOT6 |
YER088C |
Protein involved in rRNA and ribosome biogenesis |
physical |
1 |
1 |
1 |
Co-localization |
AKL1 |
YBR059C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Co-localization |
ADO1 |
YJR105W |
Adenosine kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARF1 |
YDL192W |
ADP-ribosylation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AHP1 |
YLR109W |
Thiol-specific peroxiredoxin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
DPS1 |
YLL018C |
Aspartyl-tRNA synthetase, primarily cytoplasmic |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GSP1 |
YLR293C |
Ran GTPase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
FAA4 |
YMR246W |
Long chain fatty acyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GET2 |
YER083C |
Subunit of the GET complex |
physical |
1 |
1 |
1 |
Co-localization |
CAF120 |
YNL278W |
Part of the CCR4-NOT transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLN1 |
YMR199W |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
GPD2 |
YOL059W |
NAD-dependent glycerol 3-phosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAR1 |
YJL157C |
CDK inhibitor and nuclear anchor |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ERG27 |
YLR100W |
3-keto sterol reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FUM1 |
YPL262W |
Fumarase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG1 |
YGR175C |
Squalene epoxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADH3 |
YMR083W |
Mitochondrial alcohol dehydrogenase isozyme III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
physical |
1 |
1 |
1 |
Co-localization |
DSK2 |
YMR276W |
Nuclear-enriched ubiquitin-like polyubiquitin-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
physical |
1 |
1 |
1 |
Co-localization |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
physical |
1 |
1 |
1 |
Proximity Label-MS |
PEF1 |
YGR058W |
Penta-EF-hand protein |
physical |
1 |
1 |
1 |
Two-hybrid |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
NMD5 |
YJR132W |
Karyopherin |
physical |
1 |
1 |
1 |
Co-localization |
SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Biochemical Activity |
PTC2 |
YER089C |
Type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPL42A |
YNL162W |
Ribosomal 60S subunit protein L42A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
THP1 |
YOL072W |
Nuclear pore-associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SCH9 |
YHR205W |
AGC family protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RSC3 |
YDR303C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
STH1 |
YIL126W |
ATPase component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
MCM4 |
YPR019W |
Essential helicase component of heterohexameric MCM2-7 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PSF2 |
YJL072C |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
HRP1 |
YOL123W |
Subunit of cleavage factor I |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NSR1 |
YGR159C |
Nucleolin, nucleolar protein that binds nuclear localization sequences |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YAR010C |
YAR010C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STE11 |
YLR362W |
Signal transducing MEK kinase |
physical |
1 |
1 |
1 |
PCA |
YPD1 |
YDL235C |
Osmotic stress-responsive phosphorelay intermediate sensor protein |
physical |
1 |
1 |
1 |
PCA |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
physical |
1 |
1 |
1 |
Biochemical Activity |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
NUP82 |
YJL061W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
NUP1 |
YOR098C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
NUP1 |
YOR098C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
physical |
1 |
1 |
1 |
Biochemical Activity |
SLN1 |
YIL147C |
Transmembrane histidine phosphotransfer kinase and osmosensor |
physical |
1 |
1 |
1 |
Biochemical Activity |
HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIP2 |
YGL208W |
One of three alternate beta subunits of the Snf1 kinase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
physical |
1 |
1 |
1 |
PCA |
SFL1 |
YOR140W |
Transcriptional repressor and activator |
physical |
1 |
1 |
1 |
Co-localization |
VAS1 |
YGR094W |
Mitochondrial and cytoplasmic valyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Co-localization |
TOD6 |
YBL054W |
PAC motif binding protein involved in rRNA and ribosome biogenesis |
physical |
1 |
1 |
1 |
Co-localization |
TIF4632 |
YGL049C |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Co-localization |
REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
physical |
1 |
1 |
1 |
Co-localization |
TDA9 |
YML081W |
Transcription factor that regulates acetate production |
physical |
1 |
1 |
1 |
Co-localization |
PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
physical |
1 |
1 |
1 |
Co-localization |
PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TSL1 |
YML100W |
Large subunit of trehalose 6-phosphate synthase/phosphatase complex |
physical |
1 |
1 |
1 |
Co-localization |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
physical |
1 |
1 |
1 |
Co-localization |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YLR257W |
YLR257W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Co-localization |
ROD1 |
YOR018W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
physical |
1 |
1 |
1 |
Co-localization |
NTH1 |
YDR001C |
Neutral trehalase, degrades trehalose |
physical |
1 |
1 |
1 |
Co-localization |
TRK1 |
YJL129C |
Component of the Trk1p-Trk2p potassium transport system |
physical |
1 |
1 |
1 |
Co-localization |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPL14B |
YHL001W |
Ribosomal 60S subunit protein L14B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRO77 |
YBL106C |
Protein with roles in exocytosis and cation homeostasis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPR137C-B |
YPR137C-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PGM1 |
YKL127W |
Phosphoglucomutase, minor isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRS3 |
YHL011C |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SFA1 |
YDL168W |
Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NHP6A |
YPR052C |
High-mobility group (HMG) protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRE28 |
YDR532C |
Subunit of a kinetochore-microtubule binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP7 |
YGR103W |
Component of several different pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC10 |
YHR143W-A |
RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOB1 |
YOR056C |
Protein involved in proteasomal and 40S ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TPS3 |
YMR261C |
Regulatory subunit of trehalose-6-phosphate synthase/phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SBH2 |
YER019C-A |
Ssh1p-Sss1p-Sbh2p complex component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OLE1 |
YGL055W |
Delta(9) fatty acid desaturase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OLE1 |
YGL055W |
Delta(9) fatty acid desaturase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
YHM2 |
YMR241W |
Citrate and oxoglutarate carrier protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUM1 |
YDR150W |
Protein required for nuclear migration |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LEU4 |
YNL104C |
Alpha-isopropylmalate synthase (2-isopropylmalate synthase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUP45 |
YBR143C |
Polypeptide release factor (eRF1) in translation termination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRM1 |
YDR120C |
tRNA methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRO2 |
YOR323C |
Gamma-glutamyl phosphate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV6 |
YCL009C |
Regulatory subunit of acetolactate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LIA1 |
YJR070C |
Deoxyhypusine hydroxylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VTC4 |
YJL012C |
Vacuolar membrane polyphosphate polymerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN9 |
YDR427W |
Non-ATPase regulatory subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SES1 |
YDR023W |
Cytosolic seryl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PET9 |
YBL030C |
Major ADP/ATP carrier of the mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRP5 |
YGL026C |
Tryptophan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF35 |
YDR429C |
eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PHO84 |
YML123C |
High-affinity inorganic phosphate (Pi) transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RTN1 |
YDR233C |
Reticulon protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV2 |
YMR108W |
Acetolactate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URA2 |
YJL130C |
Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAM1 |
YLR180W |
S-adenosylmethionine synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22B |
YLR367W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TSA1 |
YML028W |
Thioredoxin peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS21A |
YKR057W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS5 |
YJR123W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS18B |
YML026C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LEU1 |
YGL009C |
Isopropylmalate isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILS1 |
YBL076C |
Cytoplasmic isoleucine-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
physical |
1 |
1 |
1 |
Proximity Label-MS |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
physical |
1 |
1 |
1 |
Proximity Label-MS |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
physical |
1 |
1 |
1 |
Proximity Label-MS |
SOG2 |
YOR353C |
Key component of the RAM signaling network |
physical |
1 |
1 |
1 |
Proximity Label-MS |
UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Proximity Label-MS |
YSP2 |
YDR326C |
Sterol-binding protein |
physical |
1 |
1 |
1 |
Proximity Label-MS |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
MKK1 |
YOR231W |
MAPKK involved in the protein kinase C signaling pathway |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
MOB1 |
YIL106W |
Component of the mitotic exit network |
physical |
1 |
1 |
1 |
Proximity Label-MS |
TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
physical |
1 |
1 |
1 |
Proximity Label-MS |
TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NET1 |
YJL076W |
Core subunit of the RENT complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PTC4 |
YBR125C |
Cytoplasmic type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PLC1 |
YPL268W |
Phospholipase C |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LRE1 |
YCL051W |
Protein involved in control of cell wall structure and stress response |
genetic |
1 |
1 |
1 |
Dosage Rescue |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ITR1 |
YDR497C |
Myo-inositol transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MST1 |
YKL194C |
Mitochondrial threonyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SKI2 |
YLR398C |
Ski complex component and putative RNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YTA12 |
YMR089C |
Mitochondrial inner membrane m-AAA protease component |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDR17 |
YNL264C |
Phosphatidylinositol transfer protein (PITP) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
THP3 |
YPR045C |
Protein that may have a role in transcription elongation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
TOS7 |
YOL019W |
Protein involved in secretion and cell wall organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM1 |
YMR043W |
Transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
IMP21 |
YIL154C |
Transcriptional activator involved in maintenance of ion homeostasis |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MSN1 |
YOL116W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RAD1 |
YPL022W |
Single-stranded DNA endonuclease (with Rad10p) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RAD24 |
YER173W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RDI1 |
YDL135C |
Rho GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RIM9 |
YMR063W |
Plasma membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SHE10 |
YGL228W |
Protein involved in outer spore wall assembly |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SIR3 |
YLR442C |
Silencing protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SLP1 |
YOR154W |
Glycosylated integral ER membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
PFU1 |
YDR306C |
F-box protein that regulates pheromone-dependent morphogenesis |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
IRC3 |
YDR332W |
Double-stranded DNA-dependent helicase of the DExH/D-box family |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
IRC20 |
YLR247C |
E3 ubiquitin ligase and putative helicase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MSD1 |
YPL104W |
Mitochondrial aspartyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MSH1 |
YHR120W |
DNA-binding protein of the mitochondria |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
NDE1 |
YMR145C |
Mitochondrial external NADH dehydrogenase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
PET54 |
YGR222W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
PIF1 |
YML061C |
DNA helicase, potent G-quadruplex DNA binder/unwinder |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SDH1 |
YKL148C |
Flavoprotein subunit of succinate dehydrogenase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TAR1 |
YLR154W-C |
Protein potentially involved in regulation of respiratory metabolism |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MRX14 |
YDR115W |
Putative mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
YJR098C |
YJR098C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Haploinsufficiency |
VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Haploinsufficiency |
STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
STE5 |
YDR103W |
Pheromone-responsive MAPK scaffold protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MSB1 |
YOR188W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
NDC1 |
YML031W |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
RPS9B |
YBR189W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YKR041W |
YKR041W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
MDL2 |
YPL270W |
Mitochondrial inner membrane half-type ABC transporter |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
UNG1 |
YML021C |
Uracil-DNA glycosylase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
PHD1 |
YKL043W |
Transcriptional activator that enhances pseudohyphal growth |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
STB6 |
YKL072W |
Protein that binds Sin3p in a two-hybrid assay |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
LCD1 |
YDR499W |
Essential protein required for the DNA integrity checkpoint pathways |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YDL129W |
YDL129W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
TOA2 |
YKL058W |
TFIIA small subunit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
PTC5 |
YOR090C |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SIP4 |
YJL089W |
C6 zinc cluster transcriptional activator |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
UBP11 |
YKR098C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
POG1 |
YIL122W |
DNA-binding transcriptional activator |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YHP1 |
YDR451C |
Homeobox transcriptional repressor |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SPT23 |
YKL020C |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
MSS4 |
YDR208W |
Phosphatidylinositol-4-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SGN1 |
YIR001C |
Cytoplasmic RNA-binding protein |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
THO1 |
YER063W |
Conserved nuclear RNA-binding protein |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YDL186W |
YDL186W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
QDR3 |
YBR043C |
Multidrug transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
KEL2 |
YGR238C |
Protein that negatively regulates mitotic exit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
PRP28 |
YDR243C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YRO2 |
YBR054W |
Protein with a putative role in response to acid stress |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YIL055C |
YIL055C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ROX3 |
YBL093C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
UTP11 |
YKL099C |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YIR016W |
YIR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SLY41 |
YOR307C |
Protein involved in ER-to-Golgi transport |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
PTR2 |
YKR093W |
Integral membrane peptide transporter |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ZRG8 |
YER033C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
RRP3 |
YHR065C |
Protein involved in rRNA processing |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
MBP1 |
YDL056W |
Transcription factor |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
RCF2 |
YNR018W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YFL040W |
YFL040W |
Putative transporter |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
TFG2 |
YGR005C |
TFIIF (Transcription Factor II) middle subunit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRO1 |
YDR300C |
Gamma-glutamyl kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
KIP3 |
YGL216W |
Kinesin-related antiparallel sliding motor protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ISU1 |
YPL135W |
Conserved protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRB6 |
YBR253W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDI1 |
YCL043C |
Protein disulfide isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VRG4 |
YGL225W |
Golgi GDP-mannose transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTI1 |
YGR156W |
Essential component of CPF (cleavage and polyadenylation factor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP9 |
YJL010C |
Essential subunit of U3-containing 90S preribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPE1 |
YKL059C |
Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP1 |
YNL221C |
Subunit of RNase MRP, nuclear RNase P and telomerase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM23 |
YNR017W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIC12 |
YBR262C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HXT6 |
YDR343C |
High-affinity glucose transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAC11 |
YDR488C |
Dynein intermediate chain, microtubule motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRC22 |
YEL001C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPR2 |
YEL062W |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPH1 |
YER169W |
JmjC domain-containing histone demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YER187W |
YER187W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBP2 |
YGL060W |
Central kinetochore associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR050W-A |
YHR050W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIR5 |
YJL160C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
QCR8 |
YJL166W |
Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCD2 |
YKL027W |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLL066W-B |
YLL066W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGR1 |
YCL044C |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL081W |
YGL081W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
HPM1 |
YIL110W |
AdoMet-dependent methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPH1 |
YIR002C |
3'-5' DNA helicase involved in error-free bypass of DNA lesions |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Dosage Rescue |
URA5 |
YML106W |
Major orotate phosphoribosyltransferase (OPRTase) isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET111 |
YMR257C |
Mitochondrial translational activator specific for the COX2 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUN4 |
YNL066W |
Cell wall protein related to glucanases localized in birth scars |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL10 |
YNL284C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUF1 |
YOR187W |
Mitochondrial translation elongation factor Tu (EF-Tu) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDR10 |
YOR328W |
ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRM44 |
YPL030W |
tRNA(Ser) Um(44) 2'-O-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPL039W |
YPL039W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUC1 |
YJL208C |
Major mitochondrial nuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NMA111 |
YNL123W |
Serine protease and general molecular chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
NAM2 |
YLR382C |
Mitochondrial leucyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCA1 |
YOR197W |
Ca2+-dependent cysteine protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
ICP55 |
YER078C |
Mitochondrial aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO2 |
YDR123C |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSF1 |
YPR047W |
Mitochondrial phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO85 |
YPL031C |
Cyclin-dependent kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOD1 |
YJR104C |
Cytosolic copper-zinc superoxide dismutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ULP2 |
YIL031W |
Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
LIP1 |
YMR298W |
Ceramide synthase subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RHO5 |
YNL180C |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RER1 |
YCL001W |
Protein involved in retention of membrane proteins |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SRT1 |
YMR101C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Dosage Rescue |
YCT1 |
YLL055W |
High-affinity cysteine-specific transporter |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ADE17 |
YMR120C |
Enzyme of 'de novo' purine biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HHT1 |
YBR010W |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BCK2 |
YER167W |
Serine/threonine-rich protein involved in PKC1 signaling pathway |
physical |
1 |
1 |
1 |
Co-localization |
FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ALD5 |
YER073W |
Mitochondrial aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADE6 |
YGR061C |
Formylglycinamidine-ribonucleotide (FGAM)-synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADE6 |
YGR061C |
Formylglycinamidine-ribonucleotide (FGAM)-synthetase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
CIN5 |
YOR028C |
Basic leucine zipper (bZIP) transcription factor of the yAP-1 family |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CDC7 |
YDL017W |
S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
physical |
1 |
1 |
1 |
Co-localization |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
ART5 |
YGR068C |
Protein proposed to regulate endocytosis of plasma membrane proteins |
physical |
1 |
1 |
1 |
Co-localization |
ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GMH1 |
YKR030W |
Golgi membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
GIP3 |
YPL137C |
Cytoplasmic protein that regulates protein phosphatase 1 Glc7p |
physical |
1 |
1 |
1 |
Co-localization |
DOC1 |
YGL240W |
Processivity factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX18 |
YGR062C |
Protein required for membrane insertion of C-terminus of Cox2p |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
CTK2 |
YJL006C |
Beta subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ATG2 |
YNL242W |
Peripheral membrane protein required for autophagic vesicle formation |
genetic |
1 |
1 |
1 |
Negative Genetic |
GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
CCS1 |
YMR038C |
Copper chaperone for superoxide dismutase Sod1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSY2 |
YLR258W |
Glycogen synthase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
CDC19 |
YAL038W |
Pyruvate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HKR1 |
YDR420W |
Mucin family member that functions as an osmosensor in the HOG pathway |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
BAT2 |
YJR148W |
Cytosolic branched-chain amino acid (BCAA) aminotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CHS5 |
YLR330W |
Component of the exomer complex |
physical |
1 |
1 |
1 |
Co-localization |
HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBP1 |
YJL209W |
Mitochondrial protein, regulator of COB mRNA stability and translation |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
FLO8 |
YER109C |
Transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCC1 |
YLR220W |
Vacuolar Fe2+/Mn2+ transporter |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
FUR1 |
YHR128W |
Uracil phosphoribosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CPS1 |
YJL172W |
Vacuolar carboxypeptidase S |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HMG1 |
YML075C |
HMG-CoA reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COQ9 |
YLR201C |
Protein required for ubiquinone biosynthesis and respiratory growth |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ARR3 |
YPR201W |
Plasma membrane metalloid/H+ antiporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HLR1 |
YDR528W |
Protein involved in regulation of cell wall composition and integrity |
genetic |
1 |
1 |
1 |
Dosage Rescue |
HNM1 |
YGL077C |
Plasma membrane transporter for choline, ethanolamine, and carnitine |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
FRA1 |
YLL029W |
Protein involved in negative regulation of iron regulon transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ESBP6 |
YNL125C |
Protein with similarity to monocarboxylate permeases |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
CFD1 |
YIL003W |
Highly conserved iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMP23 |
YBR047W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
AEP3 |
YPL005W |
Peripheral mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
AHK1 |
YDL073W |
Scaffold protein in the HKR1 sub-branch of the Hog1p-signaling pathway |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ACP1 |
YKL192C |
Mitochondrial matrix acyl carrier protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CHA1 |
YCL064C |
Catabolic L-serine (L-threonine) deaminase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BYE1 |
YKL005C |
Negative regulator of transcription elongation |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
FLO11 |
YIR019C |
GPI-anchored cell surface glycoprotein (flocculin) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAS1 |
YKL182W |
Beta subunit of fatty acid synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAS1 |
YKL182W |
Beta subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
AIM23 |
YJL131C |
Mitochondrial translation initiation factor 3 (IF3, mIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSA1 |
YPR174C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
GVP36 |
YIL041W |
BAR domain protein that localizes to early and late Golgi vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
physical |
1 |
1 |
1 |
Proximity Label-MS |
FYV6 |
YNL133C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DER1 |
YBR201W |
ER membrane protein that promotes export of misfolded polypeptides |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX11 |
YPL132W |
Protein required for delivery of copper to Cox1p |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ECM13 |
YBL043W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ERG4 |
YGL012W |
C-24(28) sterol reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ALG7 |
YBR243C |
UDP-N-acetyl-glucosamine-1-P transferase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATO2 |
YNR002C |
Putative transmembrane protein involved in export of ammonia |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CMI7 |
YIL002W-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMC1 |
YIL098C |
Mitochondrial matrix protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARR1 |
YPR199C |
Transcriptional activator of the basic leucine zipper (bZIP) family |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CMC2 |
YBL059C-A |
Protein involved in respiratory chain complex assembly or maintenance |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIT2 |
YDR402C |
N-formyltyrosine oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBT1 |
YKL208W |
Protein involved in 5' RNA end processing |
genetic |
1 |
1 |
1 |
Negative Genetic |