Standard name Systematic name Name description Description
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress
Visualize the interactome of HOG1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cell Periphery 0.091 NaN 0.183
Cytoplasm 0.990 0.994 0.979

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 6780

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HOG1 11 1 0 1 1

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress physical 17 6 12 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, PCA, Affinity Capture-MS, PCA, PCA, Co-localization, Affinity Capture-MS, Affinity Capture-MS
HOT1 YMR172W Transcription factor for glycerol biosynthetic genes physical 10 5 7 Two-hybrid, Two-hybrid, Biochemical Activity, Affinity Capture-MS, Co-localization, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Co-localization, Affinity Capture-MS
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 9 6 7 Synthetic Lethality, Synthetic Rescue, Dosage Rescue, Synthetic Rescue, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement, Synthetic Rescue, Dosage Rescue
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway physical 9 5 7 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, PCA, PCA, Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Affinity Capture-Western
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family physical 7 5 5 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, PCA, Co-localization, Co-localization
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 7 4 5 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Biochemical Activity, Affinity Capture-MS, Biochemical Activity
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 7 2 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CDC73 YLR418C Component of the Paf1p complex genetic 7 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 6 2 6 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 6 5 5 Phenotypic Enhancement, Synthetic Rescue, Synthetic Growth Defect, Dosage Rescue, Phenotypic Suppression, Synthetic Growth Defect
CYC8 YBR112C General transcriptional co-repressor genetic 6 2 5 Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
PTP2 YOR208W Phosphotyrosine-specific phosphatase physical 6 2 5 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport physical 6 5 4 Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Co-localization, Affinity Capture-MS, Proximity Label-MS
IRA2 YOL081W GTPase-activating protein genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 6 2 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic
MSC1 YML128C Protein of unknown function genetic 6 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) genetic 6 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 5 3 5 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) genetic 5 3 5 Synthetic Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family genetic 5 1 5 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 5 3 4 Negative Genetic, Negative Genetic, Negative Genetic, Dosage Rescue, Synthetic Growth Defect
PTK2 YJR059W Serine/threonine protein kinase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) physical 5 4 3 Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, Biochemical Activity
BRE1 YDL074C E3 ubiquitin ligase genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel physical 5 4 2 Affinity Capture-Western, Two-hybrid, Biochemical Activity, Affinity Capture-Western, PCA
MRC1 YCL061C S-phase checkpoint protein required for DNA replication physical 5 3 2 Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Biochemical Activity
RGC1 YPR115W Putative regulator of the Fps1p glycerol channel physical 4 3 4 Affinity Capture-MS, Two-hybrid, Co-localization, Affinity Capture-MS
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 4 2 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Affinity Capture-MS
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 4 2 4 Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 4 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel physical 4 4 3 Affinity Capture-MS, Biochemical Activity, Two-hybrid, Co-localization
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 4 3 3 Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Positive Genetic
TUP1 YCR084C General repressor of transcription in complex with Cyc8p genetic 4 2 3 Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Synthetic Rescue
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
KIC1 YHR102W Protein kinase of the PAK/Ste20 family, required for cell integrity physical 3 3 3 PCA, Affinity Capture-MS, Proximity Label-MS
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p physical 3 3 3 Biochemical Activity, Affinity Capture-MS, Proximity Label-MS
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 3 3 3 Synthetic Rescue, Dosage Lethality, Positive Genetic
MSB2 YGR014W Mucin family member involved in various signaling pathways genetic 3 3 3 Synthetic Rescue, Phenotypic Suppression, Dosage Growth Defect
CIK1 YMR198W Kinesin-associated protein genetic 3 3 3 Synthetic Growth Defect, Dosage Growth Defect, Negative Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 3 3 3 Phenotypic Enhancement, Phenotypic Suppression, Negative Genetic
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress genetic 3 2 3 Dosage Rescue, Phenotypic Suppression, Dosage Rescue
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 3 2 3 Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue
PTP3 YER075C Phosphotyrosine-specific protein phosphatase physical 3 2 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
STE50 YCL032W Adaptor protein for various signaling pathways genetic 3 2 3 Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways genetic 3 2 3 Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 3 2 3 Phenotypic Suppression, Phenotypic Suppression, Dosage Growth Defect
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PTP2 YOR208W Phosphotyrosine-specific phosphatase genetic 3 1 3 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YRB1 YDR002W Ran GTPase binding protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PXP1 YEL020C Peroxisomal matrix protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 3 3 2 Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 3 3 2 Synthetic Growth Defect, Dosage Rescue, Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 3 2 2 Negative Genetic, Negative Genetic, Dosage Growth Defect
GPD1 YDL022W NAD-dependent glycerol-3-phosphate dehydrogenase genetic 3 2 2 Dosage Rescue, Synthetic Growth Defect, Synthetic Growth Defect
YPD1 YDL235C Osmotic stress-responsive phosphorelay intermediate sensor protein genetic 3 1 2 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
SMP1 YBR182C MADS-box transcription factor involved in osmotic stress response physical 3 3 1 Affinity Capture-Western, Two-hybrid, Biochemical Activity
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways physical 3 3 1 Co-localization, Affinity Capture-Western, Biochemical Activity
STL1 YDR536W Glycerol proton symporter of the plasma membrane genetic 3 3 1 Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 3 2 1 Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex physical 3 2 1 Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 2 2 2 Negative Genetic, Dosage Growth Defect
RCK1 YGL158W Protein kinase involved in oxidative stress response physical 2 2 2 Affinity Capture-MS, Two-hybrid
HSP82 YPL240C Hsp90 chaperone physical 2 2 2 Two-hybrid, Affinity Capture-MS
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 2 2 2 Affinity Capture-Western, Biochemical Activity
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex physical 2 2 2 Affinity Capture-Western, Co-localization
STE50 YCL032W Adaptor protein for various signaling pathways physical 2 2 2 Biochemical Activity, Co-localization
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways physical 2 2 2 Biochemical Activity, Co-localization
SGD1 YLR336C Essential nuclear protein genetic 2 2 2 Dosage Rescue, Synthetic Lethality
SNF1 YDR477W AMP-activated S/T protein kinase genetic 2 2 2 Phenotypic Enhancement, Synthetic Rescue
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
UBP6 YFR010W Ubiquitin-specific protease genetic 2 2 2 Phenotypic Suppression, Negative Genetic
SCO1 YBR037C Copper-binding protein of mitochondrial inner membrane genetic 2 2 2 Phenotypic Suppression, Negative Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
STE4 YOR212W G protein beta subunit genetic 2 2 2 Phenotypic Suppression, Dosage Growth Defect
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 2 2 2 Synthetic Growth Defect, Dosage Growth Defect
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 2 1 2 Negative Genetic, Negative Genetic
CNB1 YKL190W Calcineurin B genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network genetic 2 1 2 Negative Genetic, Negative Genetic
PTP3 YER075C Phosphotyrosine-specific protein phosphatase genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
STE7 YDL159W Signal transducing MAP kinase kinase genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
STE11 YLR362W Signal transducing MEK kinase genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 2 1 2 Negative Genetic, Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 2 1 2 Negative Genetic, Negative Genetic
ILV3 YJR016C Dihydroxyacid dehydratase genetic 2 1 2 Negative Genetic, Negative Genetic
RSC4 YKR008W Component of the RSC chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
TKL1 YPR074C Transketolase genetic 2 1 2 Negative Genetic, Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 2 Negative Genetic, Negative Genetic
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) regulation 2 2 1 mass spectrometry evidence, physical interaction evidence
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs regulation 2 2 1 mass spectrometry evidence, physical interaction evidence
SOG2 YOR353C Key component of the RAM signaling network regulation 2 2 1 mass spectrometry evidence, physical interaction evidence
KIC1 YHR102W Protein kinase of the PAK/Ste20 family, required for cell integrity regulation 2 2 1 mass spectrometry evidence, physical interaction evidence
ORM2 YLR350W Protein that mediates sphingolipid homeostasis regulation 2 2 1 mass spectrometry evidence, physical interaction evidence
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit regulation 2 2 1 protein kinase assay evidence, qualitative western immunoblotting evidence
YSP2 YDR326C Sterol-binding protein regulation 2 2 1 mass spectrometry evidence, physical interaction evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 2 2 1 mass spectrometry evidence, physical interaction evidence
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions regulation 2 2 1 mass spectrometry evidence, physical interaction evidence
SLT2 YHR030C Serine/threonine MAP kinase regulation 2 2 1 green fluorescent protein immunolocalization evidence, qualitative western immunoblotting evidence
SSK1 YLR006C Cytoplasmic phosphorelay intermediate osmosensor and regulator regulation 2 2 1 green fluorescent protein immunolocalization evidence, qualitative western immunoblotting evidence
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane physical 2 2 1 Affinity Capture-Western, Biochemical Activity
NHA1 YLR138W Na+/H+ antiporter physical 2 2 1 Affinity Capture-Western, Biochemical Activity
HSL1 YKL101W Nim1p-related protein kinase physical 2 2 1 Affinity Capture-Western, Biochemical Activity
STE7 YDL159W Signal transducing MAP kinase kinase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication physical 2 2 1 Co-localization, Affinity Capture-Western
WHI5 YOR083W Repressor of G1 transcription physical 2 2 1 Biochemical Activity, Affinity Capture-Western
MSA1 YOR066W Activator of G1-specific transcription factors MBF and SBF physical 2 2 1 Biochemical Activity, Affinity Capture-Western
SUP35 YDR172W Translation termination factor eRF3 genetic 2 2 1 Phenotypic Suppression, Synthetic Growth Defect
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
WHI3 YNL197C RNA binding protein that modulates mRNA stability genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
SIZ1 YDR409W SUMO E3 ligase genetic 2 2 1 Dosage Growth Defect, Phenotypic Suppression
LCB1 YMR296C Component of serine palmitoyltransferase genetic 2 2 1 Synthetic Growth Defect, Dosage Rescue
KIN2 YLR096W S/T protein kinase genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
KIN1 YDR122W S/T protein kinase genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
NAB6 YML117W Putative RNA-binding protein genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis physical 2 2 1 Biochemical Activity, Affinity Capture-Western
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SOV1 YMR066W Mitochondrial protein of unknown function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SKN7 YHR206W Nuclear response regulator and transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GRE2 YOL151W 3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase regulation 1 1 1 northern blot evidence
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) regulation 1 1 1 mass spectrometry evidence
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family regulation 1 1 1 electrophoretic mobility shift assay evidence
STE20 YHL007C Cdc42p-activated signal transducing kinase regulation 1 1 1 mass spectrometry evidence
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex regulation 1 1 1 mass spectrometry evidence
NET1 YJL076W Core subunit of the RENT complex regulation 1 1 1 protein kinase assay evidence
CIP1 YPL014W Cyclin-dependent kinase inhibitor regulation 1 1 1 protein kinase assay evidence
ALD3 YMR169C Cytoplasmic aldehyde dehydrogenase regulation 1 1 1 northern blot evidence
CTT1 YGR088W Cytosolic catalase T regulation 1 1 1 northern blot evidence
STL1 YDR536W Glycerol proton symporter of the plasma membrane regulation 1 1 1 northern blot evidence
MFB1 YDR219C Mitochondria-associated F-box protein regulation 1 1 1 mass spectrometry evidence
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport regulation 1 1 1 physical interaction evidence
SPT6 YGR116W Nucleosome remodeling protein regulation 1 1 1 protein kinase assay evidence
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p regulation 1 1 1 physical interaction evidence
FAR8 YMR029C Protein involved in recovery from arrest in response to pheromone regulation 1 1 1 mass spectrometry evidence
PMD1 YER132C Protein with an N-terminal kelch-like domain regulation 1 1 1 mass spectrometry evidence
SAP1 YER047C Putative ATPase of the AAA family regulation 1 1 1 mass spectrometry evidence
RPO21 YDL140C RNA polymerase II largest subunit B220 regulation 1 1 1 protein kinase assay evidence
PKH1 YDR490C Serine/threonine protein kinase regulation 1 1 1 mass spectrometry evidence
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit regulation 1 1 1 protein kinase assay evidence
TFG1 YGR186W TFIIF (Transcription Factor II) largest subunit regulation 1 1 1 mass spectrometry evidence
ARR1 YPR199C Transcriptional activator of the basic leucine zipper (bZIP) family regulation 1 1 1 electrophoretic mobility shift assay evidence
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis regulation 1 1 1 protein kinase assay evidence
HAP1 YLR256W Zinc finger transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PKC1 YBL105C Protein serine/threonine kinase regulation 1 1 1 green fluorescent protein immunolocalization evidence
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway regulation 1 1 1 green fluorescent protein immunolocalization evidence
PTC1 YDL006W Type 2C protein phosphatase (PP2C) regulation 1 1 1 phosphatase assay evidence
SSK22 YCR073C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway regulation 1 1 1 green fluorescent protein immunolocalization evidence
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Dosage Growth Defect
ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing genetic 1 1 1 Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Affinity Capture-MS
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
HAS1 YMR290C ATP-dependent RNA helicase genetic 1 1 1 Dosage Growth Defect
AMN1 YBR158W Modulator of cell separation and mitotic exit genetic 1 1 1 Phenotypic Suppression
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Positive Genetic
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex genetic 1 1 1 Negative Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 physical 1 1 1 Affinity Capture-MS
DST1 YGL043W General transcription elongation factor TFIIS physical 1 1 1 Affinity Capture-Western
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 1 1 1 Negative Genetic
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme genetic 1 1 1 Positive Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
ARO1 YDR127W Pentafunctional arom protein physical 1 1 1 Affinity Capture-MS
BAT1 YHR208W Mitochondrial branched-chain amino acid (BCAA) aminotransferase physical 1 1 1 Affinity Capture-MS
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Synthetic Growth Defect
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Negative Genetic
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 Affinity Capture-MS
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
AIM21 YIR003W Subunit of a complex that associates with actin filaments physical 1 1 1 Co-localization
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 1 1 1 Biochemical Activity
BOI2 YER114C Protein involved in polar growth physical 1 1 1 Co-localization
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC45 YLR103C DNA replication initiation factor physical 1 1 1 Affinity Capture-Western
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
CIP1 YPL014W Cyclin-dependent kinase inhibitor physical 1 1 1 Biochemical Activity
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex physical 1 1 1 Affinity Capture-MS
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
CYR1 YJL005W Adenylate cyclase physical 1 1 1 Co-localization
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Synthetic Lethality
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Dosage Growth Defect
DPB2 YPR175W Second largest subunit of DNA polymerase II (DNA polymerase epsilon) physical 1 1 1 Affinity Capture-Western
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Dosage Growth Defect
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase physical 1 1 1 Affinity Capture-MS
EMP24 YGL200C Component of the p24 complex genetic 1 1 1 Synthetic Growth Defect
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase physical 1 1 1 Affinity Capture-MS
GCN2 YDR283C Protein kinase genetic 1 1 1 Phenotypic Suppression
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
GLY1 YEL046C Threonine aldolase physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator genetic 1 1 1 Phenotypic Suppression
HIS4 YCL030C Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase physical 1 1 1 Affinity Capture-MS
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Co-localization
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase genetic 1 1 1 Dosage Rescue
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) physical 1 1 1 Affinity Capture-MS
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Co-localization
ADA2 YDR448W Transcription coactivator physical 1 1 1 Affinity Capture-Western
CMD1 YBR109C Calmodulin physical 1 1 1 Affinity Capture-Western
FAS2 YPL231W Alpha subunit of fatty acid synthetase physical 1 1 1 Affinity Capture-MS
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Synthetic Growth Defect
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Negative Genetic
ABF2 YMR072W Mitochondrial DNA-binding protein physical 1 1 1 Affinity Capture-MS
BGL2 YGR282C Endo-beta-1,3-glucanase physical 1 1 1 Affinity Capture-MS
AVT4 YNL101W Vacuolar transporter genetic 1 1 1 Dosage Growth Defect
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization genetic 1 1 1 Dosage Growth Defect
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex physical 1 1 1 Biochemical Activity
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex physical 1 1 1 Affinity Capture-Western
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex genetic 1 1 1 Dosage Growth Defect
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
CCT7 YJL111W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CAM1 YPL048W One of two isoforms of the gamma subunit of eEF1B physical 1 1 1 Affinity Capture-MS
GLN1 YPR035W Glutamine synthetase (GS) physical 1 1 1 Affinity Capture-MS
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Co-localization
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Synthetic Growth Defect
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Positive Genetic
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 1 1 1 Co-localization
DOT6 YER088C Protein involved in rRNA and ribosome biogenesis physical 1 1 1 Co-localization
AKL1 YBR059C Ser/Thr protein kinase physical 1 1 1 Co-localization
ADO1 YJR105W Adenosine kinase physical 1 1 1 Affinity Capture-MS
ARF1 YDL192W ADP-ribosylation factor physical 1 1 1 Affinity Capture-MS
AHP1 YLR109W Thiol-specific peroxiredoxin physical 1 1 1 Affinity Capture-MS
HIR3 YJR140C Subunit of the HIR complex genetic 1 1 1 Phenotypic Suppression
DPS1 YLL018C Aspartyl-tRNA synthetase, primarily cytoplasmic physical 1 1 1 Affinity Capture-MS
GSP1 YLR293C Ran GTPase genetic 1 1 1 Phenotypic Suppression
FAA4 YMR246W Long chain fatty acyl-CoA synthetase physical 1 1 1 Affinity Capture-MS
GET2 YER083C Subunit of the GET complex physical 1 1 1 Co-localization
CAF120 YNL278W Part of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Dosage Growth Defect
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Phenotypic Suppression
GPD2 YOL059W NAD-dependent glycerol 3-phosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
FAR1 YJL157C CDK inhibitor and nuclear anchor genetic 1 1 1 Dosage Growth Defect
ERG27 YLR100W 3-keto sterol reductase physical 1 1 1 Affinity Capture-MS
FUM1 YPL262W Fumarase physical 1 1 1 Affinity Capture-MS
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
ERG1 YGR175C Squalene epoxidase physical 1 1 1 Affinity Capture-MS
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III physical 1 1 1 Affinity Capture-MS
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Negative Genetic
ARE2 YNR019W Acyl-CoA:sterol acyltransferase physical 1 1 1 Co-localization
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein physical 1 1 1 Affinity Capture-MS
BUL1 YMR275C Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Co-localization
CDC37 YDR168W Essential Hsp90p co-chaperone physical 1 1 1 Affinity Capture-Western
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Synthetic Lethality
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Synthetic Growth Defect
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Negative Genetic
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 1 1 1 Proximity Label-MS
PEF1 YGR058W Penta-EF-hand protein physical 1 1 1 Two-hybrid
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes physical 1 1 1 Affinity Capture-Western
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly physical 1 1 1 Affinity Capture-Western
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-Western
NMD5 YJR132W Karyopherin physical 1 1 1 Co-localization
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Phenotypic Enhancement
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Phenotypic Enhancement
PTC1 YDL006W Type 2C protein phosphatase (PP2C) physical 1 1 1 Biochemical Activity
PTC2 YER089C Type 2C protein phosphatase (PP2C) physical 1 1 1 Biochemical Activity
RPL42A YNL162W Ribosomal 60S subunit protein L42A physical 1 1 1 Affinity Capture-MS
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation physical 1 1 1 Affinity Capture-Western
THP1 YOL072W Nuclear pore-associated protein physical 1 1 1 Affinity Capture-Western
SCH9 YHR205W AGC family protein kinase physical 1 1 1 Affinity Capture-Western
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes physical 1 1 1 Affinity Capture-Western
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-Western
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
RSC3 YDR303C Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-Western
RSC9 YML127W Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-Western
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Rescue
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-Western
MCM4 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes physical 1 1 1 Affinity Capture-Western
PSF2 YJL072C Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) physical 1 1 1 Affinity Capture-Western
HRP1 YOL123W Subunit of cleavage factor I physical 1 1 1 Affinity Capture-MS
NSR1 YGR159C Nucleolin, nucleolar protein that binds nuclear localization sequences physical 1 1 1 Affinity Capture-MS
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B physical 1 1 1 Affinity Capture-MS
YAR010C YAR010C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
STE11 YLR362W Signal transducing MEK kinase physical 1 1 1 PCA
YPD1 YDL235C Osmotic stress-responsive phosphorelay intermediate sensor protein physical 1 1 1 PCA
MSN2 YMR037C Stress-responsive transcriptional activator physical 1 1 1 Biochemical Activity
MSN2 YMR037C Stress-responsive transcriptional activator genetic 1 1 1 Synthetic Growth Defect
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger physical 1 1 1 Affinity Capture-MS
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Dosage Growth Defect
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Dosage Growth Defect
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-Western
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-Western
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-Western
NUP1 YOR098C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Biochemical Activity
NUP1 YOR098C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Dosage Growth Defect
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway physical 1 1 1 Biochemical Activity
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor physical 1 1 1 Biochemical Activity
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
SIP2 YGL208W One of three alternate beta subunits of the Snf1 kinase complex physical 1 1 1 Biochemical Activity
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex physical 1 1 1 PCA
SFL1 YOR140W Transcriptional repressor and activator physical 1 1 1 Co-localization
VAS1 YGR094W Mitochondrial and cytoplasmic valyl-tRNA synthetase physical 1 1 1 Co-localization
TOD6 YBL054W PAC motif binding protein involved in rRNA and ribosome biogenesis physical 1 1 1 Co-localization
TIF4632 YGL049C Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Co-localization
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p physical 1 1 1 Co-localization
TDA9 YML081W Transcription factor that regulates acetate production physical 1 1 1 Co-localization
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p physical 1 1 1 Co-localization
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 1 1 1 Synthetic Rescue
TSL1 YML100W Large subunit of trehalose 6-phosphate synthase/phosphatase complex physical 1 1 1 Co-localization
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor physical 1 1 1 Co-localization
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Synthetic Lethality
YLR257W YLR257W Protein of unknown function physical 1 1 1 Co-localization
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis physical 1 1 1 Co-localization
NTH1 YDR001C Neutral trehalase, degrades trehalose physical 1 1 1 Co-localization
TRK1 YJL129C Component of the Trk1p-Trk2p potassium transport system physical 1 1 1 Co-localization
SPT6 YGR116W Nucleosome remodeling protein physical 1 1 1 Biochemical Activity
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 1 1 1 Biochemical Activity
RPL14B YHL001W Ribosomal 60S subunit protein L14B physical 1 1 1 Affinity Capture-MS
SRO77 YBL106C Protein with roles in exocytosis and cation homeostasis physical 1 1 1 Affinity Capture-MS
YPR137C-B YPR137C-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis physical 1 1 1 Affinity Capture-MS
PGM1 YKL127W Phosphoglucomutase, minor isoform physical 1 1 1 Affinity Capture-MS
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
SUP35 YDR172W Translation termination factor eRF3 physical 1 1 1 Affinity Capture-MS
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Affinity Capture-MS
SFA1 YDL168W Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer physical 1 1 1 Affinity Capture-MS
NHP6A YPR052C High-mobility group (HMG) protein physical 1 1 1 Affinity Capture-MS
KRE28 YDR532C Subunit of a kinetochore-microtubule binding complex physical 1 1 1 Affinity Capture-MS
NOP7 YGR103W Component of several different pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
RPC10 YHR143W-A RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III physical 1 1 1 Affinity Capture-MS
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis physical 1 1 1 Affinity Capture-MS
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
TPS3 YMR261C Regulatory subunit of trehalose-6-phosphate synthase/phosphatase physical 1 1 1 Affinity Capture-MS
SBH2 YER019C-A Ssh1p-Sss1p-Sbh2p complex component physical 1 1 1 Affinity Capture-MS
OLE1 YGL055W Delta(9) fatty acid desaturase physical 1 1 1 Affinity Capture-MS
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 1 1 1 Phenotypic Suppression
YHM2 YMR241W Citrate and oxoglutarate carrier protein physical 1 1 1 Affinity Capture-MS
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
NUM1 YDR150W Protein required for nuclear migration physical 1 1 1 Affinity Capture-MS
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 Affinity Capture-MS
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p physical 1 1 1 Affinity Capture-MS
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) physical 1 1 1 Affinity Capture-MS
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex physical 1 1 1 Affinity Capture-MS
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 1 1 1 Negative Genetic
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination physical 1 1 1 Affinity Capture-MS
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 1 1 1 Affinity Capture-MS
TUP1 YCR084C General repressor of transcription in complex with Cyc8p physical 1 1 1 Affinity Capture-MS
TRM1 YDR120C tRNA methyltransferase physical 1 1 1 Affinity Capture-MS
PRO2 YOR323C Gamma-glutamyl phosphate reductase physical 1 1 1 Affinity Capture-MS
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism physical 1 1 1 Affinity Capture-MS
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase physical 1 1 1 Affinity Capture-MS
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
ILV6 YCL009C Regulatory subunit of acetolactate synthase physical 1 1 1 Affinity Capture-MS
LIA1 YJR070C Deoxyhypusine hydroxylase physical 1 1 1 Affinity Capture-MS
NEW1 YPL226W Translation termination and ribosome biogenesis factor physical 1 1 1 Affinity Capture-MS
RET2 YFR051C Delta subunit of the coatomer complex (COPI) physical 1 1 1 Affinity Capture-MS
VTC4 YJL012C Vacuolar membrane polyphosphate polymerase physical 1 1 1 Affinity Capture-MS
RPN9 YDR427W Non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
SES1 YDR023W Cytosolic seryl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF physical 1 1 1 Affinity Capture-MS
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
TRP5 YGL026C Tryptophan synthase physical 1 1 1 Affinity Capture-MS
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway genetic 1 1 1 Dosage Growth Defect
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TIF35 YDR429C eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 1 1 1 Affinity Capture-MS
RTN1 YDR233C Reticulon protein physical 1 1 1 Affinity Capture-MS
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
ILV2 YMR108W Acetolactate synthase physical 1 1 1 Affinity Capture-MS
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase physical 1 1 1 Affinity Capture-MS
SAM1 YLR180W S-adenosylmethionine synthetase physical 1 1 1 Affinity Capture-MS
RPS22B YLR367W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Affinity Capture-MS
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Negative Genetic
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 1 1 1 Affinity Capture-MS
TSA1 YML028W Thioredoxin peroxidase physical 1 1 1 Affinity Capture-MS
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS1B YML063W Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS18B YML026C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
LEU1 YGL009C Isopropylmalate isomerase physical 1 1 1 Affinity Capture-MS
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase physical 1 1 1 Affinity Capture-MS
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
HSF1 YGL073W Trimeric heat shock transcription factor physical 1 1 1 Proximity Label-MS
ORM2 YLR350W Protein that mediates sphingolipid homeostasis physical 1 1 1 Proximity Label-MS
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs physical 1 1 1 Proximity Label-MS
SOG2 YOR353C Key component of the RAM signaling network physical 1 1 1 Proximity Label-MS
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Proximity Label-MS
YSP2 YDR326C Sterol-binding protein physical 1 1 1 Proximity Label-MS
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 Affinity Capture-Western
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-Western
MOB1 YIL106W Component of the mitotic exit network physical 1 1 1 Proximity Label-MS
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) physical 1 1 1 Proximity Label-MS
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Negative Genetic
NET1 YJL076W Core subunit of the RENT complex physical 1 1 1 Biochemical Activity
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Synthetic Lethality
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Phenotypic Enhancement
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 1 1 1 Synthetic Rescue
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 1 1 1 Synthetic Rescue
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Positive Genetic
SSK1 YLR006C Cytoplasmic phosphorelay intermediate osmosensor and regulator genetic 1 1 1 Synthetic Rescue
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 1 1 1 Synthetic Rescue
PLC1 YPL268W Phospholipase C genetic 1 1 1 Synthetic Lethality
LRE1 YCL051W Protein involved in control of cell wall structure and stress response genetic 1 1 1 Dosage Rescue
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Synthetic Growth Defect
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Synthetic Growth Defect
ITR1 YDR497C Myo-inositol transporter genetic 1 1 1 Synthetic Growth Defect
MST1 YKL194C Mitochondrial threonyl-tRNA synthetase genetic 1 1 1 Synthetic Growth Defect
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Synthetic Growth Defect
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Synthetic Growth Defect
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
PDR17 YNL264C Phosphatidylinositol transfer protein (PITP) genetic 1 1 1 Synthetic Growth Defect
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Synthetic Growth Defect
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Synthetic Growth Defect
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Positive Genetic
TOS7 YOL019W Protein involved in secretion and cell wall organization genetic 1 1 1 Negative Genetic
MCM1 YMR043W Transcription factor genetic 1 1 1 Phenotypic Suppression
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Synthetic Rescue
RRD2 YPL152W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Synthetic Rescue
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Phenotypic Suppression
IMP21 YIL154C Transcriptional activator involved in maintenance of ion homeostasis genetic 1 1 1 Phenotypic Suppression
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Phenotypic Suppression
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Phenotypic Suppression
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Phenotypic Suppression
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Phenotypic Suppression
RAD24 YER173W Checkpoint protein genetic 1 1 1 Phenotypic Suppression
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Phenotypic Suppression
RDI1 YDL135C Rho GDP dissociation inhibitor genetic 1 1 1 Phenotypic Suppression
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Phenotypic Suppression
SHE10 YGL228W Protein involved in outer spore wall assembly genetic 1 1 1 Phenotypic Suppression
SIR3 YLR442C Silencing protein genetic 1 1 1 Phenotypic Suppression
SLP1 YOR154W Glycosylated integral ER membrane protein of unknown function genetic 1 1 1 Phenotypic Suppression
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Phenotypic Suppression
PFU1 YDR306C F-box protein that regulates pheromone-dependent morphogenesis genetic 1 1 1 Phenotypic Suppression
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Phenotypic Suppression
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Phenotypic Suppression
IRC3 YDR332W Double-stranded DNA-dependent helicase of the DExH/D-box family genetic 1 1 1 Phenotypic Suppression
IRC20 YLR247C E3 ubiquitin ligase and putative helicase genetic 1 1 1 Phenotypic Suppression
MSD1 YPL104W Mitochondrial aspartyl-tRNA synthetase genetic 1 1 1 Phenotypic Suppression
MSH1 YHR120W DNA-binding protein of the mitochondria genetic 1 1 1 Phenotypic Suppression
NDE1 YMR145C Mitochondrial external NADH dehydrogenase genetic 1 1 1 Phenotypic Suppression
PET54 YGR222W Mitochondrial inner membrane protein genetic 1 1 1 Phenotypic Suppression
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder genetic 1 1 1 Phenotypic Suppression
SDH1 YKL148C Flavoprotein subunit of succinate dehydrogenase genetic 1 1 1 Phenotypic Suppression
TAR1 YLR154W-C Protein potentially involved in regulation of respiratory metabolism genetic 1 1 1 Phenotypic Suppression
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Phenotypic Suppression
MRX14 YDR115W Putative mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Phenotypic Suppression
YJR098C YJR098C Putative protein of unknown function genetic 1 1 1 Phenotypic Suppression
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 1 1 1 Synthetic Growth Defect
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Haploinsufficiency
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Synthetic Haploinsufficiency
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade genetic 1 1 1 Phenotypic Suppression
STE5 YDR103W Pheromone-responsive MAPK scaffold protein genetic 1 1 1 Phenotypic Suppression
MSB1 YOR188W Protein of unknown function genetic 1 1 1 Dosage Growth Defect
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Dosage Growth Defect
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Dosage Growth Defect
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Dosage Growth Defect
ZAP1 YJL056C Zinc-regulated transcription factor genetic 1 1 1 Dosage Growth Defect
NDC1 YML031W Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 1 1 1 Dosage Growth Defect
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Dosage Growth Defect
YKR041W YKR041W Protein of unknown function genetic 1 1 1 Dosage Growth Defect
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Dosage Growth Defect
UNG1 YML021C Uracil-DNA glycosylase genetic 1 1 1 Dosage Growth Defect
PHD1 YKL043W Transcriptional activator that enhances pseudohyphal growth genetic 1 1 1 Dosage Growth Defect
STB6 YKL072W Protein that binds Sin3p in a two-hybrid assay genetic 1 1 1 Dosage Growth Defect
LCD1 YDR499W Essential protein required for the DNA integrity checkpoint pathways genetic 1 1 1 Dosage Growth Defect
YDL129W YDL129W Protein of unknown function genetic 1 1 1 Dosage Growth Defect
TOA2 YKL058W TFIIA small subunit genetic 1 1 1 Dosage Growth Defect
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Dosage Growth Defect
SIP4 YJL089W C6 zinc cluster transcriptional activator genetic 1 1 1 Dosage Growth Defect
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Dosage Growth Defect
UBP11 YKR098C Ubiquitin-specific protease genetic 1 1 1 Dosage Growth Defect
POG1 YIL122W DNA-binding transcriptional activator genetic 1 1 1 Dosage Growth Defect
YHP1 YDR451C Homeobox transcriptional repressor genetic 1 1 1 Dosage Growth Defect
SPT23 YKL020C ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Dosage Growth Defect
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 1 1 1 Dosage Growth Defect
SGN1 YIR001C Cytoplasmic RNA-binding protein genetic 1 1 1 Dosage Growth Defect
THO1 YER063W Conserved nuclear RNA-binding protein genetic 1 1 1 Dosage Growth Defect
YDL186W YDL186W Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
QDR3 YBR043C Multidrug transporter of the major facilitator superfamily genetic 1 1 1 Dosage Growth Defect
KEL2 YGR238C Protein that negatively regulates mitotic exit genetic 1 1 1 Dosage Growth Defect
PRP28 YDR243C Pre-mRNA splicing factor genetic 1 1 1 Dosage Growth Defect
YRO2 YBR054W Protein with a putative role in response to acid stress genetic 1 1 1 Dosage Growth Defect
YIL055C YIL055C Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
ROX3 YBL093C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Dosage Growth Defect
UTP11 YKL099C Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Dosage Growth Defect
YIR016W YIR016W Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
SLY41 YOR307C Protein involved in ER-to-Golgi transport genetic 1 1 1 Dosage Growth Defect
PTR2 YKR093W Integral membrane peptide transporter genetic 1 1 1 Dosage Growth Defect
ZRG8 YER033C Protein of unknown function genetic 1 1 1 Dosage Growth Defect
RRP3 YHR065C Protein involved in rRNA processing genetic 1 1 1 Dosage Growth Defect
MBP1 YDL056W Transcription factor genetic 1 1 1 Dosage Growth Defect
RCF2 YNR018W Cytochrome c oxidase subunit genetic 1 1 1 Dosage Growth Defect
YFL040W YFL040W Putative transporter genetic 1 1 1 Dosage Growth Defect
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Dosage Growth Defect
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit genetic 1 1 1 Dosage Growth Defect
MSN4 YKL062W Stress-responsive transcriptional activator genetic 1 1 1 Synthetic Growth Defect
PRO1 YDR300C Gamma-glutamyl kinase genetic 1 1 1 Dosage Rescue
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Phenotypic Suppression
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 1 1 1 Phenotypic Enhancement
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Synthetic Growth Defect
ISU1 YPL135W Conserved protein of the mitochondrial matrix genetic 1 1 1 Phenotypic Enhancement
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Phenotypic Suppression
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Positive Genetic
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome genetic 1 1 1 Positive Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Positive Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Positive Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Positive Genetic
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Negative Genetic
SRB6 YBR253W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
PDI1 YCL043C Protein disulfide isomerase genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking genetic 1 1 1 Negative Genetic
PCF11 YDR228C mRNA 3' end processing factor genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Negative Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
VRG4 YGL225W Golgi GDP-mannose transporter genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Negative Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
PGA2 YNL149C Essential protein required for maturation of Gas1p and Pho8p genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
RPB11 YOL005C RNA polymerase II subunit B12.5 genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
MIC12 YBR262C Component of the MICOS complex genetic 1 1 1 Negative Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
HXT6 YDR343C High-affinity glucose transporter genetic 1 1 1 Negative Genetic
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 1 1 1 Negative Genetic
IRC22 YEL001C Protein of unknown function genetic 1 1 1 Negative Genetic
NPR2 YEL062W Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
RPH1 YER169W JmjC domain-containing histone demethylase genetic 1 1 1 Negative Genetic
YER187W YER187W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YBP2 YGL060W Central kinetochore associated protein genetic 1 1 1 Negative Genetic
YHR050W-A YHR050W-A Protein of unknown function genetic 1 1 1 Negative Genetic
PIR5 YJL160C Putative protein of unknown function genetic 1 1 1 Negative Genetic
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
TCD2 YKL027W tRNA threonylcarbamoyladenosine dehydratase genetic 1 1 1 Negative Genetic
YLL066W-B YLL066W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
YGL081W YGL081W Putative protein of unknown function genetic 1 1 1 Negative Genetic
KEL1 YHR158C Protein required for proper cell fusion and cell morphology genetic 1 1 1 Negative Genetic
HPM1 YIL110W AdoMet-dependent methyltransferase genetic 1 1 1 Negative Genetic
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions genetic 1 1 1 Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Dosage Rescue
URA5 YML106W Major orotate phosphoribosyltransferase (OPRTase) isozyme genetic 1 1 1 Negative Genetic
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA genetic 1 1 1 Negative Genetic
SUN4 YNL066W Cell wall protein related to glucanases localized in birth scars genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 1 1 1 Negative Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
TUF1 YOR187W Mitochondrial translation elongation factor Tu (EF-Tu) genetic 1 1 1 Negative Genetic
PDR10 YOR328W ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic
TRM44 YPL030W tRNA(Ser) Um(44) 2'-O-methyltransferase genetic 1 1 1 Negative Genetic
YPL039W YPL039W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Positive Genetic
NUC1 YJL208C Major mitochondrial nuclease genetic 1 1 1 Negative Genetic
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 genetic 1 1 1 Negative Genetic
NMA111 YNL123W Serine protease and general molecular chaperone genetic 1 1 1 Positive Genetic
NAM2 YLR382C Mitochondrial leucyl-tRNA synthetase genetic 1 1 1 Negative Genetic
MCA1 YOR197W Ca2+-dependent cysteine protease genetic 1 1 1 Positive Genetic
ICP55 YER078C Mitochondrial aminopeptidase genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Positive Genetic
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Positive Genetic
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Negative Genetic
MSF1 YPR047W Mitochondrial phenylalanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Positive Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Negative Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Negative Genetic
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins genetic 1 1 1 Phenotypic Suppression
LIP1 YMR298W Ceramide synthase subunit genetic 1 1 1 Synthetic Growth Defect
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Phenotypic Suppression
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Phenotypic Enhancement
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Synthetic Growth Defect
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
RER1 YCL001W Protein involved in retention of membrane proteins genetic 1 1 1 Dosage Rescue
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Dosage Rescue
SRT1 YMR101C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Dosage Rescue
YCT1 YLL055W High-affinity cysteine-specific transporter genetic 1 1 1 Synthetic Rescue
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 1 1 1 Phenotypic Suppression
ADE17 YMR120C Enzyme of 'de novo' purine biosynthesis physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway physical 1 1 1 Co-localization
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Phenotypic Suppression
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Negative Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Dosage Rescue
ALD5 YER073W Mitochondrial aldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
ADE6 YGR061C Formylglycinamidine-ribonucleotide (FGAM)-synthetase physical 1 1 1 Affinity Capture-MS
ADE6 YGR061C Formylglycinamidine-ribonucleotide (FGAM)-synthetase genetic 1 1 1 Phenotypic Suppression
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family genetic 1 1 1 Dosage Rescue
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) physical 1 1 1 Affinity Capture-Western
ERG11 YHR007C Lanosterol 14-alpha-demethylase physical 1 1 1 Co-localization
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Negative Genetic
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Synthetic Rescue
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Phenotypic Suppression
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Positive Genetic
ART5 YGR068C Protein proposed to regulate endocytosis of plasma membrane proteins physical 1 1 1 Co-localization
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Dosage Growth Defect
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
GMH1 YKR030W Golgi membrane protein of unknown function genetic 1 1 1 Dosage Growth Defect
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p physical 1 1 1 Co-localization
DOC1 YGL240W Processivity factor genetic 1 1 1 Negative Genetic
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family genetic 1 1 1 Synthetic Growth Defect
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Synthetic Growth Defect
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Dosage Growth Defect
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-MS
CLC1 YGR167W Clathrin light chain genetic 1 1 1 Negative Genetic
COX18 YGR062C Protein required for membrane insertion of C-terminus of Cox2p genetic 1 1 1 Phenotypic Suppression
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Dosage Growth Defect
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation genetic 1 1 1 Negative Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Dosage Growth Defect
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p physical 1 1 1 Affinity Capture-MS
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
GSY2 YLR258W Glycogen synthase genetic 1 1 1 Dosage Growth Defect
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 1 1 1 Synthetic Rescue
BAT2 YJR148W Cytosolic branched-chain amino acid (BCAA) aminotransferase physical 1 1 1 Affinity Capture-MS
CHS5 YLR330W Component of the exomer complex physical 1 1 1 Co-localization
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Negative Genetic
CBP1 YJL209W Mitochondrial protein, regulator of COB mRNA stability and translation genetic 1 1 1 Phenotypic Suppression
FLO8 YER109C Transcription factor genetic 1 1 1 Phenotypic Suppression
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane physical 1 1 1 Affinity Capture-MS
CCC1 YLR220W Vacuolar Fe2+/Mn2+ transporter genetic 1 1 1 Dosage Growth Defect
FUR1 YHR128W Uracil phosphoribosyltransferase physical 1 1 1 Affinity Capture-MS
CPS1 YJL172W Vacuolar carboxypeptidase S physical 1 1 1 Affinity Capture-MS
HMG1 YML075C HMG-CoA reductase physical 1 1 1 Affinity Capture-MS
COQ9 YLR201C Protein required for ubiquinone biosynthesis and respiratory growth genetic 1 1 1 Phenotypic Suppression
ARR3 YPR201W Plasma membrane metalloid/H+ antiporter genetic 1 1 1 Synthetic Growth Defect
HLR1 YDR528W Protein involved in regulation of cell wall composition and integrity genetic 1 1 1 Dosage Rescue
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine genetic 1 1 1 Dosage Growth Defect
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription physical 1 1 1 Affinity Capture-MS
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Positive Genetic
ESBP6 YNL125C Protein with similarity to monocarboxylate permeases genetic 1 1 1 Dosage Growth Defect
CFD1 YIL003W Highly conserved iron-sulfur cluster binding protein genetic 1 1 1 Negative Genetic
FMP23 YBR047W Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
AEP3 YPL005W Peripheral mitochondrial inner membrane protein genetic 1 1 1 Phenotypic Suppression
AHK1 YDL073W Scaffold protein in the HKR1 sub-branch of the Hog1p-signaling pathway genetic 1 1 1 Dosage Growth Defect
ACP1 YKL192C Mitochondrial matrix acyl carrier protein physical 1 1 1 Affinity Capture-MS
CHA1 YCL064C Catabolic L-serine (L-threonine) deaminase physical 1 1 1 Affinity Capture-MS
ALD6 YPL061W Cytosolic aldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
BYE1 YKL005C Negative regulator of transcription elongation genetic 1 1 1 Dosage Growth Defect
FLO11 YIR019C GPI-anchored cell surface glycoprotein (flocculin) genetic 1 1 1 Phenotypic Suppression
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
FAS1 YKL182W Beta subunit of fatty acid synthetase physical 1 1 1 Affinity Capture-MS
FAS1 YKL182W Beta subunit of fatty acid synthetase genetic 1 1 1 Dosage Growth Defect
AIM23 YJL131C Mitochondrial translation initiation factor 3 (IF3, mIF3) genetic 1 1 1 Negative Genetic
CSA1 YPR174C Protein of unknown function genetic 1 1 1 Dosage Growth Defect
GVP36 YIL041W BAR domain protein that localizes to early and late Golgi vesicles genetic 1 1 1 Negative Genetic
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 1 1 1 Proximity Label-MS
FYV6 YNL133C Protein of unknown function genetic 1 1 1 Dosage Growth Defect
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Positive Genetic
DER1 YBR201W ER membrane protein that promotes export of misfolded polypeptides genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
COX11 YPL132W Protein required for delivery of copper to Cox1p genetic 1 1 1 Phenotypic Suppression
ECM13 YBL043W Non-essential protein of unknown function genetic 1 1 1 Dosage Rescue
ERG4 YGL012W C-24(28) sterol reductase physical 1 1 1 Affinity Capture-MS
ALG7 YBR243C UDP-N-acetyl-glucosamine-1-P transferase genetic 1 1 1 Dosage Rescue
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Synthetic Growth Defect
ATO2 YNR002C Putative transmembrane protein involved in export of ammonia genetic 1 1 1 Phenotypic Suppression
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 1 1 1 Synthetic Growth Defect
CMI7 YIL002W-A Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Negative Genetic
ARR1 YPR199C Transcriptional activator of the basic leucine zipper (bZIP) family genetic 1 1 1 Phenotypic Enhancement
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Growth Defect
CMC2 YBL059C-A Protein involved in respiratory chain complex assembly or maintenance genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
DIT2 YDR402C N-formyltyrosine oxidase genetic 1 1 1 Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Negative Genetic