SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
physical |
3 |
2 |
2 |
Two-hybrid, Affinity Capture-MS, Two-hybrid |
PHO80 |
YOL001W |
Cyclin |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SMC5 |
YOL034W |
Subunit of the SMC5-SMC6 complex |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
YKL033W-A |
YKL033W-A |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MEK1 |
YOR351C |
Meiosis-specific serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
CBF2 |
YGR140W |
Essential kinetochore protein |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERR1 |
YOR393W |
Putative phosphopyruvate hydratase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
physical |
2 |
2 |
1 |
Reconstituted Complex, Two-hybrid |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
regulation |
1 |
1 |
1 |
mass spectrometry evidence |
CHA4 |
YLR098C |
DNA binding transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
UBC9 |
YDL064W |
SUMO-conjugating enzyme involved in the Smt3p conjugation pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC9 |
YGR009C |
t-SNARE protein required for secretory vesicle-plasma membrane fusion |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB4 |
YPR056W |
Subunit of TFIIH complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Positive Genetic |
YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
USE1 |
YGL098W |
Essential SNARE protein localized to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC97 |
YHR172W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR210W |
YDR210W |
Predicted tail-anchored plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR156C-A |
YLR156C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR407W |
YLR407W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAN1 |
YPL126W |
U3 snoRNP protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIR2 |
YDL175C |
RNA-binding subunit of the TRAMP nuclear RNA surveillance complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIS3 |
YOL021C |
Exosome core complex catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE8 |
YML092C |
Alpha 2 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PUF6 |
YDR496C |
Pumilio-homology domain protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
IOC3 |
YFR013W |
Subunit of the Isw1a complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAP7 |
YDL166C |
Essential NTPase required for small ribosome subunit synthesis |
physical |
1 |
1 |
1 |
Two-hybrid |
LAS17 |
YOR181W |
Actin assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DIB1 |
YPR082C |
17-kDa component of the U4/U6aU5 tri-snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD51 |
YER095W |
Strand exchange protein |
physical |
1 |
1 |
1 |
Two-hybrid |
PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Two-hybrid |
LSB3 |
YFR024C-A |
Protein containing a C-terminal SH3 domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSH4 |
YFL003C |
Protein involved in meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIM1 |
YPL266W |
Essential 18S rRNA dimethylase (dimethyladenosine transferase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PCT1 |
YGR202C |
Cholinephosphate cytidylyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
physical |
1 |
1 |
1 |
Two-hybrid |
NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PEX13 |
YLR191W |
Peroxisomal importomer complex component |
physical |
1 |
1 |
1 |
Two-hybrid |
RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC21 |
YOR074C |
Thymidylate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG23 |
YLR431C |
Peripheral membrane protein required for autophagy and CVT |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYO3 |
YKL129C |
One of two type I myosins |
physical |
1 |
1 |
1 |
Two-hybrid |
MYO5 |
YMR109W |
One of two type I myosin motors |
physical |
1 |
1 |
1 |
Two-hybrid |
DPH2 |
YKL191W |
Protein required for synthesis of diphthamide |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
HUB1 |
YNR032C-A |
Ubiquitin-like protein modifier |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRS1 |
YOR294W |
Essential protein that binds ribosomal protein L11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
physical |
1 |
1 |
1 |
Two-hybrid |
RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BYE1 |
YKL005C |
Negative regulator of transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRX18 |
YBR056W |
Putative glycoside hydrolase of the mitochondrial intermembrane space |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Two-hybrid |
QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIT2 |
YDR402C |
N-formyltyrosine oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAL4 |
YIR028W |
Allantoin permease |
genetic |
1 |
1 |
1 |
Negative Genetic |