Standard name Systematic name Name description Description
FAP7 YDL166C Essential NTPase required for small ribosome subunit synthesis Essential NTPase required for small ribosome subunit synthesis; mediates processing of the 20S pre-rRNA at site D in the cytoplasm but associates only transiently with 43S preribosomes via Rps14p; complex with Rps14 is conserved between humans, yeast, and arches; may be the endonuclease for site D; depletion leads to accumulation of pre-40S ribosomes in 80S-like ribosomes; human TAF9 functionally complements the lethality of the null mutation
Visualize the interactome of FAP7
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.054 0.087 0.066
Nucleolus 0.066 NaN NaN
Nucleus 0.548 0.484 0.553
Vac/Vac Memb 0.392 0.478 0.428

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 8350

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
FAP7 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1729 (deoxyadenylate kinase), r_0148 (adenylate kinase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 8 4 6 Affinity Capture-MS, Affinity Capture-MS, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Two-hybrid
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS14B YJL191W Protein component of the small (40S) ribosomal subunit physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Dosage Rescue
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly physical 1 1 1 Biochemical Activity
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase physical 1 1 1 Biochemical Activity
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway physical 1 1 1 Biochemical Activity
PRK1 YIL095W Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
SAP1 YER047C Putative ATPase of the AAA family physical 1 1 1 Two-hybrid
PEX6 YNL329C AAA-peroxin physical 1 1 1 Two-hybrid
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS24A YER074W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 1 1 1 Affinity Capture-MS
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 1 1 1 Affinity Capture-MS
RPL6A YML073C Ribosomal 60S subunit protein L6A physical 1 1 1 Affinity Capture-MS
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
RPL11A YPR102C Ribosomal 60S subunit protein L11A physical 1 1 1 Affinity Capture-MS
RPL12A YEL054C Ribosomal 60S subunit protein L12A physical 1 1 1 Affinity Capture-MS
RPL14A YKL006W Ribosomal 60S subunit protein L14A physical 1 1 1 Affinity Capture-MS
RPL23A YBL087C Ribosomal 60S subunit protein L23A physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
TIF1 YKR059W Translation initiation factor eIF4A physical 1 1 1 Affinity Capture-MS
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Affinity Capture-MS
HYP2 YEL034W Translation elongation factor eIF-5A physical 1 1 1 Affinity Capture-MS
TSA1 YML028W Thioredoxin peroxidase physical 1 1 1 Affinity Capture-MS
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF physical 1 1 1 Affinity Capture-MS
VMA4 YOR332W Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) physical 1 1 1 Affinity Capture-MS
SAM1 YLR180W S-adenosylmethionine synthetase physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 PCA
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 PCA
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Reconstituted Complex
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 physical 1 1 1 Reconstituted Complex
KAP123 YER110C Karyopherin beta physical 1 1 1 Reconstituted Complex
MSN5 YDR335W Karyopherin physical 1 1 1 Reconstituted Complex
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TSR2 YLR435W Protein with a potential role in pre-rRNA processing genetic 1 1 1 Dosage Rescue
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Synthetic Rescue
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) genetic 1 1 1 Synthetic Rescue