Standard name Systematic name Name description Description
SAM1 YLR180W S-adenosylmethionine synthetase S-adenosylmethionine synthetase; catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; SAM1 has a paralog, SAM2, that arose from the whole genome duplication
Visualize the interactome of SAM1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 14

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.993 0.993 1.0

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 103000

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SAM1 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0726 (methionine adenosyltransferase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SAM2 YDR502C S-adenosylmethionine synthetase genetic 15 5 10 Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression
SAM2 YDR502C S-adenosylmethionine synthetase physical 5 4 4 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Co-fractionation, Affinity Capture-Western
CDC19 YAL038W Pyruvate kinase physical 5 4 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Co-localization
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex physical 4 3 1 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-localization
ABD1 YBR236C Methyltransferase genetic 3 3 3 Dosage Rescue, Phenotypic Enhancement, Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ACS2 YLR153C Acetyl-coA synthetase isoform physical 3 2 2 Affinity Capture-MS, Co-fractionation, Affinity Capture-MS
SER33 YIL074C 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase physical 3 3 1 Co-fractionation, Affinity Capture-Western, Co-localization
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
HSP82 YPL240C Hsp90 chaperone genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
SAM1 YLR180W S-adenosylmethionine synthetase physical 2 2 2 Two-hybrid, Co-fractionation
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 2 1 2 Negative Genetic, Negative Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 2 1 2 Negative Genetic, Negative Genetic
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPN2 YIL075C Subunit of the 26S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
BAT1 YHR208W Mitochondrial branched-chain amino acid (BCAA) aminotransferase genetic 2 1 2 Negative Genetic, Negative Genetic
HHF1 YBR009C Histone H4 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LCB2 YDR062W Component of serine palmitoyltransferase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 2 1 2 Negative Genetic, Negative Genetic
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TRP2 YER090W Anthranilate synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
URA7 YBL039C Major CTP synthase isozyme (see also URA8) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 2 1 2 Negative Genetic, Negative Genetic
SKI7 YOR076C GTP-binding protein that couples the Ski complex and exosome genetic 2 1 2 Negative Genetic, Negative Genetic
TKL1 YPR074C Transketolase genetic 2 1 2 Negative Genetic, Negative Genetic
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 2 1 2 Negative Genetic, Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 2 1 2 Negative Genetic, Negative Genetic
CDC31 YOR257W Calcium-binding component of the spindle pole body (SPB) half-bridge physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 2 1 2 Positive Genetic, Positive Genetic
MSS1 YMR023C Mitochondrial protein genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
RPE1 YJL121C D-ribulose-5-phosphate 3-epimerase genetic 2 1 2 Negative Genetic, Negative Genetic
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase physical 2 2 1 Co-fractionation, Affinity Capture-Western
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 2 2 1 Negative Genetic, Positive Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
RTC6 YPL183W-A Protein involved in translation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 DNA to cDNA expression microarray evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
MET31 YPL038W Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
RPB2 YOR151C RNA polymerase II second largest subunit B150 physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
NUC1 YJL208C Major mitochondrial nuclease genetic 1 1 1 Negative Genetic
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Positive Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Negative Genetic
RPC31 YNL151C RNA polymerase III subunit C31 genetic 1 1 1 Negative Genetic
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Synthetic Growth Defect
KAP95 YLR347C Karyopherin beta physical 1 1 1 Affinity Capture-MS
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 1 1 1 Negative Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Positive Genetic
ARO1 YDR127W Pentafunctional arom protein physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Positive Genetic
CAF40 YNL288W Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Affinity Capture-MS
CDC10 YCR002C Component of the septin ring, required for cytokinesis physical 1 1 1 Affinity Capture-MS
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping physical 1 1 1 Affinity Capture-MS
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 1 1 1 Affinity Capture-MS
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase physical 1 1 1 Affinity Capture-MS
HIS4 YCL030C Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase physical 1 1 1 Affinity Capture-MS
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing genetic 1 1 1 Positive Genetic
CLU1 YMR012W Subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
KGD2 YDR148C Dihydrolipoyl transsuccinylase physical 1 1 1 Affinity Capture-MS
FAP7 YDL166C Essential NTPase required for small ribosome subunit synthesis physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase physical 1 1 1 Affinity Capture-MS
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Co-fractionation
MYO1 YHR023W Type II myosin heavy chain physical 1 1 1 Affinity Capture-MS
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Positive Genetic
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping physical 1 1 1 Affinity Capture-MS
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
PIM1 YBL022C ATP-dependent Lon protease physical 1 1 1 Affinity Capture-MS
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
DBP8 YHR169W ATPase, putative RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
GPM1 YKL152C Tetrameric phosphoglycerate mutase physical 1 1 1 Affinity Capture-MS
RET2 YFR051C Delta subunit of the coatomer complex (COPI) physical 1 1 1 Affinity Capture-MS
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) physical 1 1 1 Affinity Capture-MS
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade physical 1 1 1 Affinity Capture-MS
TUB3 YML124C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
TUB1 YML085C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
YHR020W YHR020W Prolyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
TRP3 YKL211C Indole-3-glycerol-phosphate synthase physical 1 1 1 Affinity Capture-MS
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis physical 1 1 1 Affinity Capture-MS
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase physical 1 1 1 Affinity Capture-MS
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Protein-RNA
YGK3 YOL128C Protein kinase related to mammalian GSK-3 glycogen synthase kinases physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
UBI4 YLL039C Ubiquitin physical 1 1 1 Affinity Capture-MS
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes physical 1 1 1 Affinity Capture-MS
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Negative Genetic
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
SER3 YER081W 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase physical 1 1 1 Co-fractionation
SER1 YOR184W 3-phosphoserine aminotransferase physical 1 1 1 Co-fractionation
SUP35 YDR172W Translation termination factor eRF3 physical 1 1 1 Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation physical 1 1 1 Affinity Capture-MS
VID24 YBR105C GID Complex regulatory subunit physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
SMC6 YLR383W Subunit of the SMC5-SMC6 complex physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Negative Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Negative Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Positive Genetic
YNK1 YKL067W Nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
TPS3 YMR261C Regulatory subunit of trehalose-6-phosphate synthase/phosphatase genetic 1 1 1 Negative Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Phenotypic Suppression
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Positive Genetic
YCR102C YCR102C Putative quinone oxidoreductase genetic 1 1 1 Positive Genetic
YDL157C YDL157C Putative protein of unknown function genetic 1 1 1 Positive Genetic
YPL039W YPL039W Putative protein of unknown function genetic 1 1 1 Positive Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Positive Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
SUI3 YPL237W Beta subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
YCL001W-A YCL001W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YCL002C YCL002C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YIL055C YIL055C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
YML053C YML053C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
TOM7 YNL070W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
SMM1 YNR015W Dihydrouridine synthase genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Negative Genetic
SKP2 YNL311C F-box protein of unknown function genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex physical 1 1 1 Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
BNA3 YJL060W Kynurenine aminotransferase genetic 1 1 1 Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Rescue
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 1 1 1 Negative Genetic
ACO1 YLR304C Aconitase physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Positive Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
MAE1 YKL029C Mitochondrial malic enzyme physical 1 1 1 Affinity Capture-MS
PSK2 YOL045W PAS-domain containing serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV genetic 1 1 1 Positive Genetic
MET6 YER091C Cobalamin-independent methionine synthase genetic 1 1 1 Phenotypic Enhancement
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Positive Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-MS
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Positive Genetic
KIC1 YHR102W Protein kinase of the PAK/Ste20 family, required for cell integrity physical 1 1 1 Affinity Capture-MS
MKK2 YPL140C MAPKK involved in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-MS
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport physical 1 1 1 Affinity Capture-MS
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Positive Genetic
MET16 YPR167C 3'-phosphoadenylsulfate reductase genetic 1 1 1 Positive Genetic
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein genetic 1 1 1 Negative Genetic
RNR3 YIL066C Minor isoform of large subunit of ribonucleotide-diphosphate reductase genetic 1 1 1 Negative Genetic
DHR2 YKL078W Predominantly nucleolar DEAH-box ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis genetic 1 1 1 Negative Genetic
ATG16 YMR159C Conserved protein involved in autophagy genetic 1 1 1 Negative Genetic
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Positive Genetic
ACO2 YJL200C Putative mitochondrial aconitase isozyme genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
ACA1 YER045C ATF/CREB family basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Negative Genetic
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation genetic 1 1 1 Negative Genetic
MRX16 YDR132C Protein that associates with the large mitoribosomal subunit genetic 1 1 1 Negative Genetic
DAS2 YDR020C Putative protein of unknown function genetic 1 1 1 Negative Genetic
ADP1 YCR011C Putative ATP-dependent permease of the ABC transporter family genetic 1 1 1 Negative Genetic
ERC1 YHR032W Member of the multi-drug and toxin extrusion (MATE) family genetic 1 1 1 Phenotypic Suppression
LAA2 YBL010C Clathrin adaptor (adaptin) accessory protein genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex physical 1 1 1 Affinity Capture-MS
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Negative Genetic
MYO5 YMR109W One of two type I myosin motors genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
RSM19 YNR037C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Negative Genetic
MOB1 YIL106W Component of the mitotic exit network physical 1 1 1 Affinity Capture-MS
RRN11 YML043C Component of the core factor (CF) rDNA transcription factor complex genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Positive Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
ERG25 YGR060W C-4 methyl sterol oxidase genetic 1 1 1 Positive Genetic
DSE1 YER124C Daughter cell-specific protein genetic 1 1 1 Negative Genetic
OTU1 YFL044C Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
EFT1 YOR133W Elongation factor 2 (EF-2), also encoded by EFT2 physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
ARO80 YDR421W Zinc finger transcriptional activator of the Zn2Cys6 family genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
PEX1 YKL197C AAA-peroxin genetic 1 1 1 Negative Genetic
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
ATG32 YIL146C Mitochondrial outer membrane protein required to initiate mitophagy genetic 1 1 1 Positive Genetic
ALD6 YPL061W Cytosolic aldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
ALD6 YPL061W Cytosolic aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
PDR15 YDR406W Plasma membrane ATP binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
BIL1 YOR304C-A Protein that binds Bud6p and has a role in actin cable assembly genetic 1 1 1 Positive Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
FAS1 YKL182W Beta subunit of fatty acid synthetase physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PSA1 YDL055C GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) physical 1 1 1 Affinity Capture-MS
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
HEM1 YDR232W 5-aminolevulinate synthase genetic 1 1 1 Negative Genetic
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PDX3 YBR035C Pyridoxine (pyridoxamine) phosphate oxidase genetic 1 1 1 Negative Genetic
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
ECM7 YLR443W Putative integral membrane protein with a role in calcium uptake genetic 1 1 1 Negative Genetic
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
HXT2 YMR011W High-affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
MUP1 YGR055W High affinity methionine permease genetic 1 1 1 Dosage Growth Defect
ERP4 YOR016C Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Phenotypic Suppression
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Positive Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Positive Genetic
PEX8 YGR077C Intraperoxisomal organizer of the peroxisomal import machinery genetic 1 1 1 Negative Genetic
JLP2 YMR132C Protein of unknown function genetic 1 1 1 Negative Genetic
ECM18 YDR125C Protein of unknown function genetic 1 1 1 Negative Genetic
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Positive Genetic