| MLC2 |
YPR188C |
Regulatory light chain for the type II myosin Myo1p |
physical |
7 |
3 |
6 |
Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| MLC1 |
YGL106W |
Essential light chain for Myo1p |
physical |
7 |
2 |
6 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
6 |
2 |
6 |
Dosage Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Synthetic Lethality |
| INN1 |
YNL152W |
Essential protein that associates with contractile actomyosin ring |
genetic |
5 |
4 |
5 |
Dosage Rescue, Synthetic Rescue, Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
5 |
3 |
5 |
Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
physical |
5 |
3 |
4 |
Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
| IQG1 |
YPL242C |
Actin filament binding protein that enhances actin ring formation |
genetic |
4 |
3 |
3 |
Dosage Rescue, Synthetic Rescue, Dosage Rescue, Synthetic Growth Defect |
| BNI5 |
YNL166C |
Linker protein responsible for recruitment of myosin to the bud neck |
physical |
3 |
3 |
3 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS |
| MYO1 |
YHR023W |
Type II myosin heavy chain |
physical |
3 |
2 |
3 |
Two-hybrid, Two-hybrid, Affinity Capture-MS |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
physical |
3 |
2 |
2 |
FRET, Two-hybrid, Two-hybrid |
| SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
physical |
3 |
1 |
2 |
Two-hybrid, Two-hybrid, Two-hybrid |
| NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
physical |
3 |
2 |
1 |
PCA, Two-hybrid, Two-hybrid |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
| CDC42 |
YLR229C |
Small rho-like GTPase |
genetic |
2 |
2 |
2 |
Dosage Growth Defect, Synthetic Rescue |
| BNI1 |
YNL271C |
Formin |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Lethality |
| MLC1 |
YGL106W |
Essential light chain for Myo1p |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Dosage Rescue |
| SPA2 |
YLL021W |
Component of the polarisome |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-Western |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MYO4 |
YAL029C |
Type V myosin motor involved in actin-based transport of cargos |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CDC5 |
YMR001C |
Polo-like kinase required for mitotic exit |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| IQG1 |
YPL242C |
Actin filament binding protein that enhances actin ring formation |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
| CHS3 |
YBR023C |
Chitin synthase III |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
| ILS1 |
YBL076C |
Cytoplasmic isoleucine-tRNA synthetase |
physical |
2 |
2 |
1 |
PCA, Affinity Capture-Western |
| HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
physical |
2 |
2 |
1 |
PCA, Affinity Capture-Western |
| FBA1 |
YKL060C |
Fructose 1,6-bisphosphate aldolase |
physical |
2 |
2 |
1 |
Affinity Capture-Western, PCA |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
2 |
2 |
1 |
PCA, Affinity Capture-Western |
| PDI1 |
YCL043C |
Protein disulfide isomerase |
physical |
2 |
2 |
1 |
Affinity Capture-Western, PCA |
| RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
physical |
2 |
2 |
1 |
Affinity Capture-Western, PCA |
| TAH11 |
YJR046W |
DNA replication licensing factor |
physical |
2 |
2 |
1 |
Affinity Capture-Western, PCA |
| TRX2 |
YGR209C |
Cytoplasmic thioredoxin isoenzyme |
physical |
2 |
2 |
1 |
Affinity Capture-Western, PCA |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
2 |
1 |
PCA, Affinity Capture-Western |
| RLM1 |
YPL089C |
MADS-box transcription factor |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Phenotypic Enhancement |
| RHO1 |
YPR165W |
GTP-binding protein of the rho subfamily of Ras-like proteins |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Dosage Rescue |
| TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Synthetic Growth Defect |
| BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
physical |
2 |
2 |
1 |
Affinity Capture-Western, PCA |
| ABP1 |
YCR088W |
Actin-binding protein of the cortical actin cytoskeleton |
physical |
2 |
2 |
1 |
Affinity Capture-MS, PCA |
| MKK2 |
YPL140C |
MAPKK involved in the protein kinase C signaling pathway |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Phenotypic Enhancement |
| FPK1 |
YNR047W |
Ser/Thr protein kinase |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
| APE2 |
YKL157W |
Aminopeptidase yscII |
physical |
2 |
2 |
1 |
Affinity Capture-Western, PCA |
| CDC19 |
YAL038W |
Pyruvate kinase |
physical |
2 |
2 |
1 |
PCA, Affinity Capture-Western |
| INN1 |
YNL152W |
Essential protein that associates with contractile actomyosin ring |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
2 |
2 |
1 |
FRET, Two-hybrid |
| ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
physical |
2 |
2 |
1 |
PCA, Affinity Capture-Western |
| DOS2 |
YDR068W |
Protein of unknown function |
physical |
2 |
2 |
1 |
PCA, Affinity Capture-Western |
| CHS2 |
YBR038W |
Chitin synthase II |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
| TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
| VPS20 |
YMR077C |
Myristoylated subunit of the ESCRT-III complex |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
| HSP78 |
YDR258C |
Oligomeric mitochondrial matrix chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
| HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
physical |
1 |
1 |
1 |
Two-hybrid |
| DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
physical |
1 |
1 |
1 |
Two-hybrid |
| ADH1 |
YOL086C |
Alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CIC1 |
YHR052W |
Essential protein that interacts with proteasome components |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BDF1 |
YLR399C |
BET family transcriptional regulator |
physical |
1 |
1 |
1 |
Two-hybrid |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| GCN2 |
YDR283C |
Protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
physical |
1 |
1 |
1 |
Two-hybrid |
| HRP1 |
YOL123W |
Subunit of cleavage factor I |
physical |
1 |
1 |
1 |
PCA |
| ECM29 |
YHL030W |
Scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
physical |
1 |
1 |
1 |
Two-hybrid |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| CCM1 |
YGR150C |
Mitochondrial 15S rRNA-binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
physical |
1 |
1 |
1 |
Two-hybrid |
| SLU7 |
YDR088C |
RNA splicing factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| SPR3 |
YGR059W |
Sporulation-specific homolog of the CDC3/10/11/12 family of genes |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNP1 |
YIL061C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Two-hybrid |
| SPA2 |
YLL021W |
Component of the polarisome |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PWP1 |
YLR196W |
Protein with WD-40 repeats involved in rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
physical |
1 |
1 |
1 |
Two-hybrid |
| VPS5 |
YOR069W |
Nexin-1 homolog |
physical |
1 |
1 |
1 |
Two-hybrid |
| UFE1 |
YOR075W |
t-SNARE protein required for retrograde vesicular traffic |
physical |
1 |
1 |
1 |
Two-hybrid |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
physical |
1 |
1 |
1 |
Two-hybrid |
| SCC2 |
YDR180W |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
physical |
1 |
1 |
1 |
Two-hybrid |
| VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
physical |
1 |
1 |
1 |
Two-hybrid |
| PSP1 |
YDR505C |
Asn and gln rich protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| PSP1 |
YDR505C |
Asn and gln rich protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| VAB2 |
YEL005C |
Subunit of the BLOC-1 complex involved in endosomal maturation |
physical |
1 |
1 |
1 |
Two-hybrid |
| NTR2 |
YKR022C |
Essential protein that forms a dimer with Ntr1p |
physical |
1 |
1 |
1 |
Two-hybrid |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
| SKS1 |
YPL026C |
Putative serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
| YTA6 |
YPL074W |
Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family |
physical |
1 |
1 |
1 |
Two-hybrid |
| NCA2 |
YPR155C |
Protein that regulates expression of Fo-F1 ATP synthase subunits |
physical |
1 |
1 |
1 |
Two-hybrid |
| VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
physical |
1 |
1 |
1 |
Two-hybrid |
| VAS1 |
YGR094W |
Mitochondrial and cytoplasmic valyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Two-hybrid |
| STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Two-hybrid |
| YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
physical |
1 |
1 |
1 |
Two-hybrid |
| TYE7 |
YOR344C |
Serine-rich protein that contains a bHLH DNA binding motif |
physical |
1 |
1 |
1 |
Two-hybrid |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PXA2 |
YKL188C |
Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p |
physical |
1 |
1 |
1 |
PCA |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| UBI4 |
YLL039C |
Ubiquitin |
physical |
1 |
1 |
1 |
PCA |
| WHI4 |
YDL224C |
Putative RNA binding protein |
physical |
1 |
1 |
1 |
PCA |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
physical |
1 |
1 |
1 |
PCA |
| YNL208W |
YNL208W |
Protein of unknown function |
physical |
1 |
1 |
1 |
PCA |
| OST1 |
YJL002C |
Alpha subunit of the oligosaccharyltransferase complex of the ER lumen |
physical |
1 |
1 |
1 |
PCA |
| OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAS10 |
YDL153C |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RTN1 |
YDR233C |
Reticulon protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL30 |
YGL030W |
Ribosomal 60S subunit protein L30 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL30 |
YGL030W |
Ribosomal 60S subunit protein L30 |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YGR283C |
YGR283C |
Putative methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RGI2 |
YIL057C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PCK1 |
YKR097W |
Phosphoenolpyruvate carboxykinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAM1 |
YLR180W |
S-adenosylmethionine synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YLR287C |
YLR287C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL36A |
YMR194W |
Ribosomal 60S subunit protein L36A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YNL050C |
YNL050C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP13 |
YNL175C |
Nucleolar protein found in preribosomal complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RGC1 |
YPR115W |
Putative regulator of the Fps1p glycerol channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NCE102 |
YPR149W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| WSS1 |
YHR134W |
SUMO-ligase and SUMO-targeted metalloprotease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RGD1 |
YBR260C |
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SRO77 |
YBL106C |
Protein with roles in exocytosis and cation homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SWM1 |
YDR260C |
Subunit of the anaphase-promoting complex (APC) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| NET1 |
YJL076W |
Core subunit of the RENT complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RPS31 |
YLR167W |
Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RCN2 |
YOR220W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RPP2B |
YDR382W |
Ribosomal protein P2 beta |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| VPS3 |
YDR495C |
Component of CORVET membrane tethering complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RPS30B |
YOR182C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| UBC1 |
YDR177W |
Ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RHO4 |
YKR055W |
Non-essential small GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HTA1 |
YDR225W |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPM1 |
YKL152C |
Tetrameric phosphoglycerate mutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
PCA |
| CAM1 |
YPL048W |
One of two isoforms of the gamma subunit of eEF1B |
physical |
1 |
1 |
1 |
PCA |
| ATP2 |
YJR121W |
Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATP4 |
YPL078C |
Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Two-hybrid |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
physical |
1 |
1 |
1 |
Two-hybrid |
| EGD1 |
YPL037C |
Subunit beta1 of the nascent polypeptide-associated complex (NAC) |
physical |
1 |
1 |
1 |
PCA |
| COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
physical |
1 |
1 |
1 |
PCA |
| HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CBK1 |
YNL161W |
Serine/threonine protein kinase of the the RAM signaling network |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| GDB1 |
YPR184W |
Glycogen debranching enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERG1 |
YGR175C |
Squalene epoxidase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| GYP5 |
YPL249C |
GTPase-activating protein (GAP) for yeast Rab family members |
physical |
1 |
1 |
1 |
Two-hybrid |
| CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KEL2 |
YGR238C |
Protein that negatively regulates mitotic exit |
physical |
1 |
1 |
1 |
PCA |
| MSS116 |
YDR194C |
Mitochondrial transcription elongation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MDH2 |
YOL126C |
Cytoplasmic malate dehydrogenase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| LAA1 |
YJL207C |
AP-1 accessory protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
PCA |
| CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| DAL82 |
YNL314W |
Positive regulator of allophanate inducible genes |
physical |
1 |
1 |
1 |
PCA |
| MND2 |
YIR025W |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| APC9 |
YLR102C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| CDC26 |
YFR036W |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| DOC1 |
YGL240W |
Processivity factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| MCM1 |
YMR043W |
Transcription factor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MOB1 |
YIL106W |
Component of the mitotic exit network |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IVY1 |
YDR229W |
Phospholipid-binding protein that interacts with both Ypt7p and Vps33p |
physical |
1 |
1 |
1 |
Two-hybrid |
| ATP1 |
YBL099W |
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ENT2 |
YLR206W |
Epsin-like protein required for endocytosis and actin patch assembly |
physical |
1 |
1 |
1 |
Two-hybrid |
| LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
physical |
1 |
1 |
1 |
Two-hybrid |
| EAF6 |
YJR082C |
Subunit of the NuA4 acetyltransferase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERG5 |
YMR015C |
C-22 sterol desaturase |
physical |
1 |
1 |
1 |
PCA |
| MMT2 |
YPL224C |
Putative metal transporter involved in mitochondrial iron accumulation |
physical |
1 |
1 |
1 |
PCA |
| MDM1 |
YML104C |
PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs |
physical |
1 |
1 |
1 |
Two-hybrid |
| MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| FUR4 |
YBR021W |
Plasma membrane localized uracil permease |
physical |
1 |
1 |
1 |
PCA |
| FMP32 |
YFL046W |
Regulator of mitochondrial proline metabolism |
physical |
1 |
1 |
1 |
Two-hybrid |
| BTT1 |
YDR252W |
Heterotrimeric nascent polypeptide-associated complex beta3 subunit |
physical |
1 |
1 |
1 |
Two-hybrid |
| MSS4 |
YDR208W |
Phosphatidylinositol-4-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| ALD4 |
YOR374W |
Mitochondrial aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CUP9 |
YPL177C |
Homeodomain-containing transcriptional repressor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MIL1 |
YFL034W |
Predicted lipase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KIN82 |
YCR091W |
Putative serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| CHS2 |
YBR038W |
Chitin synthase II |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| DSC3 |
YOR223W |
Subunit of the DSC ubiquitin ligase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| EMI1 |
YDR512C |
Non-essential protein of unknown function |
physical |
1 |
1 |
1 |
PCA |
| COX20 |
YDR231C |
Mitochondrial inner membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRPL50 |
YNR022C |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Two-hybrid |
| MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| LRE1 |
YCL051W |
Protein involved in control of cell wall structure and stress response |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
