Standard name Systematic name Name description Description
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex Subunit of the NuA4 acetyltransferase complex; this complex acetylates histone H4 and NuA3 acetyltransferase complex that acetylates histone H3
Visualize the interactome of EAF6
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.136 NaN 0.371
Nucleolus 0.094 0.127 0.186
Nucleus 0.945 0.943 0.883

GFP localization & abundance

GFP localization GFP abundance
nucleus 504

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
EAF6 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 11 3 4 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 7 3 6 Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-Western
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 7 2 6 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 7 2 6 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 7 2 5 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex physical 6 4 4 Affinity Capture-MS, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 6 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 6 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SWC3 YAL011W Protein of unknown function genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ADA2 YDR448W Transcription coactivator genetic 5 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 5 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PDP3 YLR455W Component of the NuA3b histone acetyltransferase complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex genetic 3 2 2 Positive Genetic, Synthetic Lethality, Synthetic Lethality
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 2 2 Synthetic Haploinsufficiency, Positive Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 2 2 2 Positive Genetic, Negative Genetic
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs genetic 2 1 2 Negative Genetic, Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SWC5 YBR231C Component of the SWR1 complex genetic 2 1 2 Negative Genetic, Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 2 1 2 Negative Genetic, Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 2 Negative Genetic, Negative Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 2 1 2 Negative Genetic, Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 2 1 2 Negative Genetic, Negative Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 2 1 2 Negative Genetic, Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 2 1 2 Negative Genetic, Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 2 1 2 Negative Genetic, Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 2 2 1 Negative Genetic, Positive Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 2 2 1 Negative Genetic, Positive Genetic
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BDF1 YLR399C BET family transcriptional regulator genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BIM1 YER016W Microtubule plus end-tracking protein genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
COX14 YML129C Mitochondrial cytochrome c oxidase (complex IV) assembly factor genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
RPL35A YDL191W Ribosomal 60S subunit protein L35A genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SFL1 YOR140W Transcriptional repressor and activator genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ERG2 YMR202W C-8 sterol isomerase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LDB7 YBL006C Component of the RSC chromatin remodeling complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LSM7 YNL147W Lsm (Like Sm) protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MLC2 YPR188C Regulatory light chain for the type II myosin Myo1p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PPR1 YLR014C Zinc finger transcription factor genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RNH70 YGR276C 3'-5' exoribonuclease genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SWI6 YLR182W Transcription cofactor genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TGL4 YKR089C Multifunctional lipase/hydrolase/phospholipase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LDB18 YLL049W Component of the dynactin complex genetic 2 1 1 Negative Genetic, Negative Genetic
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Positive Genetic
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Negative Genetic
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 1 1 1 Negative Genetic
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 1 1 1 Negative Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Reconstituted Complex
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Dosage Growth Defect
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Dosage Growth Defect
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein physical 1 1 1 Two-hybrid
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Positive Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector physical 1 1 1 Reconstituted Complex
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) physical 1 1 1 Reconstituted Complex
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Negative Genetic
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 1 1 1 Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase physical 1 1 1 Reconstituted Complex
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Negative Genetic
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes physical 1 1 1 Reconstituted Complex
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes physical 1 1 1 Reconstituted Complex
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 1 1 1 Reconstituted Complex
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Reconstituted Complex
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases physical 1 1 1 Reconstituted Complex
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Reconstituted Complex
YPK3 YBR028C AGC kinase physical 1 1 1 Reconstituted Complex
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
STE50 YCL032W Adaptor protein for various signaling pathways physical 1 1 1 Two-hybrid
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex physical 1 1 1 Two-hybrid
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation physical 1 1 1 Two-hybrid
MYO1 YHR023W Type II myosin heavy chain physical 1 1 1 Two-hybrid
GZF3 YJL110C GATA zinc finger protein physical 1 1 1 Two-hybrid
SPO14 YKR031C Phospholipase D physical 1 1 1 Two-hybrid
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay physical 1 1 1 Two-hybrid
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase physical 1 1 1 Two-hybrid
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body physical 1 1 1 Two-hybrid
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif physical 1 1 1 Two-hybrid
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Negative Genetic
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RPA43 YOR340C RNA polymerase I subunit A43 genetic 1 1 1 Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Positive Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Positive Genetic
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Positive Genetic
POP8 YBL018C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Positive Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex genetic 1 1 1 Positive Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Positive Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Positive Genetic
FAF1 YIL019W Protein required for pre-rRNA processing genetic 1 1 1 Positive Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex genetic 1 1 1 Positive Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Positive Genetic
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription genetic 1 1 1 Positive Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
EMG1 YLR186W Methyltransferase for rRNA genetic 1 1 1 Negative Genetic
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Dosage Growth Defect
SNU71 YGR013W Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Dosage Growth Defect
UGA4 YDL210W GABA (gamma-aminobutyrate) permease genetic 1 1 1 Dosage Growth Defect
MSN4 YKL062W Stress-responsive transcriptional activator genetic 1 1 1 Dosage Growth Defect
RAD23 YEL037C Protein with ubiquitin-like N terminus genetic 1 1 1 Dosage Growth Defect
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Dosage Growth Defect
UFO1 YML088W F-box receptor protein genetic 1 1 1 Dosage Growth Defect
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Dosage Growth Defect
MET32 YDR253C Zinc-finger DNA-binding transcription factor genetic 1 1 1 Dosage Growth Defect
YCR051W YCR051W Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p genetic 1 1 1 Dosage Growth Defect
GBP2 YCL011C Poly(A+) RNA-binding protein genetic 1 1 1 Dosage Growth Defect
GIP2 YER054C Putative regulatory subunit of protein phosphatase Glc7p genetic 1 1 1 Dosage Growth Defect
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Dosage Growth Defect
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Positive Genetic
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
FRQ1 YDR373W N-myristoylated calcium-binding protein genetic 1 1 1 Negative Genetic
RPP1 YHR062C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Negative Genetic
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Negative Genetic
PRM7 YDL039C Pheromone-regulated protein genetic 1 1 1 Negative Genetic
REF2 YDR195W RNA-binding protein genetic 1 1 1 Negative Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Negative Genetic
WWM1 YFL010C WW domain containing protein of unknown function genetic 1 1 1 Negative Genetic
PEX21 YGR239C Peroxin required for peroxisomal matrix protein targeting genetic 1 1 1 Negative Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 1 1 1 Negative Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
STB4 YMR019W Putative transcription factor genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
PLB2 YMR006C Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Negative Genetic
MMT1 YMR177W Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
SNF12 YNR023W 73 kDa subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
NBA1 YOL070C Protein involved in axial bud site selection genetic 1 1 1 Negative Genetic
IAH1 YOR126C Isoamyl acetate-hydrolyzing esterase genetic 1 1 1 Negative Genetic
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Negative Genetic
FIN1 YDR130C Spindle pole body-related intermediate filament protein genetic 1 1 1 Negative Genetic
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) genetic 1 1 1 Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Negative Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Negative Genetic
ECM30 YLR436C Protein of unknown function genetic 1 1 1 Negative Genetic
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Positive Genetic
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 1 1 1 Positive Genetic
MDM30 YLR368W F-box component of an SCF ubiquitin protein ligase complex genetic 1 1 1 Negative Genetic
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Positive Genetic
QRI7 YDL104C Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Positive Genetic
FCF1 YDR339C PINc domain endonuclease genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
KRE28 YDR532C Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Positive Genetic
NBP35 YGL091C Essential cytoplasmic iron-sulfur cluster binding protein genetic 1 1 1 Positive Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Negative Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Positive Genetic
TIF1 YKR059W Translation initiation factor eIF4A genetic 1 1 1 Negative Genetic
HBS1 YKR084C GTPase with similarity to translation release factors genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Positive Genetic
TAF4 YMR005W TFIID subunit (48 kDa) genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Positive Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Positive Genetic
MAK5 YBR142W Essential nucleolar protein genetic 1 1 1 Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
SAS4 YDR181C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 1 1 1 Negative Genetic
SEC4 YFL005W Rab family GTPase genetic 1 1 1 Negative Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 1 1 1 Negative Genetic
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
TIM13 YGR181W Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
MVB12 YGR206W ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Negative Genetic
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Negative Genetic
ZRC1 YMR243C Vacuolar membrane zinc transporter genetic 1 1 1 Negative Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Negative Genetic
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 1 1 1 Synthetic Growth Defect
BOP3 YNL042W Protein of unknown function genetic 1 1 1 Dosage Growth Defect
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Negative Genetic
CAB4 YGR277C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Negative Genetic
ANB1 YJR047C Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
DOT5 YIL010W Nuclear thiol peroxidase genetic 1 1 1 Dosage Growth Defect
ARF3 YOR094W Glucose-repressible ADP-ribosylation factor genetic 1 1 1 Negative Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Positive Genetic
AFT2 YPL202C Iron-regulated transcriptional activator genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
CIS1 YLR346C Protein of unknown function found in mitochondria genetic 1 1 1 Negative Genetic