RIX1 |
YHR197W |
Component of the Rix1 complex and possibly pre-replicative complexes |
physical |
5 |
2 |
4 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
ARX1 |
YDR101C |
Nuclear export factor for the ribosomal pre-60S subunit |
physical |
4 |
2 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western |
SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
physical |
4 |
2 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
2 |
3 |
Synthetic Haploinsufficiency, Negative Genetic, Negative Genetic |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
3 |
2 |
3 |
Affinity Capture-RNA, Affinity Capture-Western, Affinity Capture-Western |
LSG1 |
YGL099W |
Putative GTPase involved in 60S ribosomal subunit biogenesis |
physical |
3 |
1 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
physical |
2 |
2 |
2 |
Affinity Capture-RNA, Affinity Capture-Western |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MGM1 |
YOR211C |
Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MET12 |
YPL023C |
Protein with MTHFR activity in vitro |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TPA1 |
YER049W |
Prolyl hydroxylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YJL068C |
YJL068C |
Esterase that can function as an S-formylglutathione hydrolase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RSM7 |
YJR113C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
RKR1 |
YMR247C |
RING domain E3 ubiquitin ligase |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
EAF6 |
YJR082C |
Subunit of the NuA4 acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
STP1 |
YDR463W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
IFH1 |
YLR223C |
Coactivator, regulates transcription of ribosomal protein (RP) genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-seq evidence |
NOG1 |
YPL093W |
Putative GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NSA1 |
YGL111W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
physical |
1 |
1 |
1 |
Co-purification |
RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RMP1 |
YLR145W |
Subunit of RNase MRP |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CIC1 |
YHR052W |
Essential protein that interacts with proteasome components |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC33 |
YOL139C |
Translation initiation factor eIF4E |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
NPL3 |
YDR432W |
RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPC31 |
YNL151C |
RNA polymerase III subunit C31 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Positive Genetic |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
MPE1 |
YKL059C |
Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOG2 |
YNR053C |
Putative GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM29 |
YHL030W |
Scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRP21 |
YBL090W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL20 |
YKR085C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Positive Genetic |
NMD3 |
YHR170W |
Protein involved in nuclear export of the large ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
NOC4 |
YPR144C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PHO84 |
YML123C |
High-affinity inorganic phosphate (Pi) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMP2 |
YML057W |
Calcineurin A |
genetic |
1 |
1 |
1 |
Negative Genetic |
PST2 |
YDR032C |
FMN-dependent NAD(P)H:quinone oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLC8 |
YMR311C |
Regulatory subunit of protein phosphatase 1 (Glc7p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
EGD1 |
YPL037C |
Subunit beta1 of the nascent polypeptide-associated complex (NAC) |
physical |
1 |
1 |
1 |
Co-purification |
HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP13 |
YNL175C |
Nucleolar protein found in preribosomal complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD9 |
YGR041W |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP53 |
YPL146C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Co-purification |
MUS81 |
YDR386W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
QCR7 |
YDR529C |
Subunit 7 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
1 |
1 |
1 |
Positive Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DLS1 |
YJL065C |
Subunit of ISW2/yCHRAC chromatin accessibility complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUT3 |
YKL015W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
DET1 |
YDR051C |
Acid phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA15 |
YGL044C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CST9 |
YLR394W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO2 |
YDL106C |
Homeobox transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCH1 |
YNL281W |
Heat shock protein regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
DSE1 |
YER124C |
Daughter cell-specific protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET28 |
YIR017C |
bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
OSH3 |
YHR073W |
Member of an oxysterol-binding protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL18B |
YNL301C |
Ribosomal 60S subunit protein L18B |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL13A |
YDL082W |
Ribosomal 60S subunit protein L13A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PLP1 |
YDR183W |
Protein that interacts with CCT (chaperonin containing TCP-1) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG7 |
YHR072W |
Lanosterol synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAP1 |
YLR244C |
Methionine aminopeptidase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
FMP23 |
YBR047W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
HOB2 |
YPR117W |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADE12 |
YNL220W |
Adenylosuccinate synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PET130 |
YJL023C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PML39 |
YML107C |
Protein required for nuclear retention of unspliced pre-mRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
URA7 |
YBL039C |
Major CTP synthase isozyme (see also URA8) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RTT102 |
YGR275W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RSA4 |
YCR072C |
Ribosomal large subunit (60S) assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YTM1 |
YOR272W |
Ribosomal assembly factor and 66S pre-ribosomal particle constituent |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RQC1 |
YDR333C |
Component of the ribosome quality control complex (RQC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL7B |
YPL198W |
Ribosomal 60S subunit protein L7B |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPL37A |
YLR185W |
Ribosomal 60S subunit protein L37A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCD6 |
YPR129W |
Repressor of translation initiation |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
YEN1 |
YER041W |
Holliday junction resolvase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLX1 |
YBR228W |
Endonuclease involved in DNA recombination and repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI73 |
YLR004C |
Putative plasma membrane permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YAL064W |
YAL064W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPL039W |
YPL039W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPP41 |
YDR464W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC5 |
YOL034W |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCR016W |
YCR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLM5 |
YCR024C |
Mitochondrial asparaginyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB3 |
YDR169C |
Ribosomal RNA processing element (RRPE)-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT31 |
YER031C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS45 |
YGL095C |
Protein of the Sec1p/Munc-18 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPF1 |
YKL100C |
Intramembrane aspartyl protease of the perinuclear ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHH4 |
YLR164W |
Putative alternate subunit of succinate dehydrogenase (SDH) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOM7 |
YNL070W |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDD3 |
YOL098C |
Putative metalloprotease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR012W |
YOR012W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
WHI5 |
YOR083W |
Repressor of G1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR186W |
YOR186W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSP2 |
YOR242C |
Sporulation specific protein that localizes to the spore wall |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR381W-A |
YOR381W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SVL3 |
YPL032C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
genetic |
1 |
1 |
1 |
Positive Genetic |
NCR1 |
YPL006W |
Vacuolar membrane protein involved with Npc2p in sterol trafficking |
genetic |
1 |
1 |
1 |
Positive Genetic |
RDL1 |
YOR285W |
Thiosulfate sulfurtransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EFG1 |
YGR271C-A |
Ribosome biogenesis factor required for maturation of 18S rRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERR1 |
YOR393W |
Putative phosphopyruvate hydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RMR1 |
YGL250W |
Protein required for meiotic recombination and gene conversion |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSN1 |
YOL116W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
MLO127 |
YJR039W |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL33A |
YPL143W |
Ribosomal 60S subunit protein L33A |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRX14 |
YDR115W |
Putative mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAL11 |
YGR289C |
High-affinity maltose transporter (alpha-glucoside transporter) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENV9 |
YOR246C |
Conserved oxidoreductase involved in lipid droplet morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
OAR1 |
YKL055C |
Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSH1 |
YHR120W |
DNA-binding protein of the mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM14 |
YHR132C |
Conserved fungal protein with similarity to zinc carboxypeptidases |
genetic |
1 |
1 |
1 |
Negative Genetic |
DML1 |
YMR211W |
Essential protein involved in mtDNA inheritance |
genetic |
1 |
1 |
1 |
Negative Genetic |
APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADF1 |
YCL058W-A |
Transcriptional repressor encoded by the FYV5 antisense strand |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPT2 |
YPL148C |
Phosphopantetheine:protein transferase (PPTase) |
genetic |
1 |
1 |
1 |
Negative Genetic |