Standard name Systematic name Name description Description
NOP53 YPL146C Nucleolar protein Nucleolar protein; involved in biogenesis of the 60S subunit of the ribosome; interacts with rRNA processing factors Cbf5p and Nop2p and with the nucleolar proteins Nop17p and Nip7p; null mutant is viable but growth is severely impaired
Visualize the interactome of NOP53
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleus 0.907 0.741 0.814
Vac/Vac Memb 0.117 0.285 0.137
Cytoplasm NaN NaN 0.053

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NOP53 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MTR4 YJL050W RNA duplex-sensing translocase physical 9 5 4 Affinity Capture-MS, Reconstituted Complex, Co-crystal Structure, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Reconstituted Complex
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit physical 7 3 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Co-purification, Affinity Capture-MS
NOG2 YNR053C Putative GTPase physical 7 2 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS
NOG1 YPL093W Putative GTPase physical 5 2 5 Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
SPB1 YCL054W AdoMet-dependent methyltransferase physical 4 4 3 Two-hybrid, Affinity Capture-Western, Co-purification, Affinity Capture-MS
RPL3 YOR063W Ribosomal 60S subunit protein L3 physical 3 3 3 Co-fractionation, Co-purification, Affinity Capture-MS
NOP7 YGR103W Component of several different pre-ribosomal particles physical 3 3 3 Two-hybrid, Co-purification, Affinity Capture-MS
CIC1 YHR052W Essential protein that interacts with proteasome components physical 3 2 3 Affinity Capture-MS, Co-purification, Affinity Capture-MS
SDA1 YGR245C Protein required for actin organization and passage through Start physical 3 2 3 Affinity Capture-MS, Co-purification, Affinity Capture-MS
RSA4 YCR072C Ribosomal large subunit (60S) assembly factor physical 3 2 3 Affinity Capture-MS, Co-purification, Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component physical 3 2 2 Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) physical 3 2 1 Two-hybrid, Two-hybrid, Reconstituted Complex
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly physical 2 2 2 Affinity Capture-MS, Two-hybrid
FPR4 YLR449W Peptidyl-prolyl cis-trans isomerase (PPIase) physical 2 2 2 Affinity Capture-MS, Two-hybrid
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) physical 2 2 2 Affinity Capture-MS, Two-hybrid
PAP2 YOL115W Non-canonical poly(A) polymerase physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
RPL24A YGL031C Ribosomal 60S subunit protein L24A physical 2 2 2 Two-hybrid, Co-purification
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 2 2 2 Co-purification, Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 2 2 2 Co-purification, Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 2 2 2 Co-purification, Affinity Capture-MS
ATG1 YGL180W Protein serine/threonine kinase physical 2 2 2 Biochemical Activity, Two-hybrid
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NOP15 YNL110C Constituent of 66S pre-ribosomal particles physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ALB1 YJL122W Shuttling pre-60S factor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NOP53 YPL146C Nucleolar protein physical 2 1 2 Two-hybrid, Two-hybrid
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA physical 2 2 1 Two-hybrid, Affinity Capture-Western
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 2 1 1 Two-hybrid, Two-hybrid
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Negative Genetic
ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing physical 1 1 1 Affinity Capture-MS
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis physical 1 1 1 Two-hybrid
NOP2 YNL061W rRNA m5C methyltransferase physical 1 1 1 Affinity Capture-MS
IMH1 YLR309C Protein involved in vesicular transport physical 1 1 1 Two-hybrid
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
NOC2 YOR206W Protein involved in ribosome biogenesis physical 1 1 1 Two-hybrid
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes physical 1 1 1 Two-hybrid
FUN12 YAL035W Translation initiation factor eIF5B physical 1 1 1 Two-hybrid
MAK21 YDR060W Constituent of 66S pre-ribosomal particles physical 1 1 1 Two-hybrid
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 1 1 1 Affinity Capture-MS
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 1 1 1 Two-hybrid
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly physical 1 1 1 Affinity Capture-MS
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
ERG26 YGL001C C-3 sterol dehydrogenase genetic 1 1 1 Positive Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Affinity Capture-MS
DPB2 YPR175W Second largest subunit of DNA polymerase II (DNA polymerase epsilon) physical 1 1 1 Affinity Capture-MS
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking physical 1 1 1 Two-hybrid
BDF2 YDL070W Protein involved in transcription initiation physical 1 1 1 Two-hybrid
DYN1 YKR054C Cytoplasmic heavy chain dynein physical 1 1 1 Two-hybrid
KIN3 YAR018C Nonessential serine/threonine protein kinase physical 1 1 1 Two-hybrid
END3 YNL084C EH domain-containing protein involved in endocytosis physical 1 1 1 Two-hybrid
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase genetic 1 1 1 Negative Genetic
MAK5 YBR142W Essential nucleolar protein physical 1 1 1 Affinity Capture-MS
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex physical 1 1 1 Two-hybrid
NIC96 YFR002W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Two-hybrid
NOC4 YPR144C Nucleolar protein physical 1 1 1 Affinity Capture-MS
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
DPS1 YLL018C Aspartyl-tRNA synthetase, primarily cytoplasmic physical 1 1 1 Two-hybrid
FDO1 YMR144W Protein involved in directionality of mating type switching physical 1 1 1 Two-hybrid
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
ETP1 YHL010C Protein of unknown function required for growth on ethanol physical 1 1 1 Two-hybrid
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone physical 1 1 1 Two-hybrid
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
ARE1 YCR048W Acyl-CoA:sterol acyltransferase physical 1 1 1 Two-hybrid
KEL2 YGR238C Protein that negatively regulates mitotic exit physical 1 1 1 Two-hybrid
GIS4 YML006C CAAX box containing protein of unknown function genetic 1 1 1 Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen physical 1 1 1 Two-hybrid
PRP9 YDL030W Subunit of the SF3a splicing factor complex physical 1 1 1 Two-hybrid
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Co-purification
SAW1 YAL027W 5'- and 3'-flap DNA binding protein physical 1 1 1 Affinity Capture-MS
OAF1 YAL051W Oleate-activated transcription factor physical 1 1 1 Affinity Capture-MS
YCR043C YCR043C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
TSR1 YDL060W Protein required for processing of 20S pre-rRNA in the cytoplasm physical 1 1 1 Affinity Capture-MS
NSE4 YDL105W Component of the SMC5-SMC6 complex physical 1 1 1 Affinity Capture-MS
UTP22 YGR090W Component of the small-subunit processome physical 1 1 1 Affinity Capture-MS
TSR2 YLR435W Protein with a potential role in pre-rRNA processing physical 1 1 1 Affinity Capture-MS
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) physical 1 1 1 Affinity Capture-MS
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 1 1 1 Affinity Capture-MS
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase physical 1 1 1 Affinity Capture-MS
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Biochemical Activity
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Positive Genetic
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
PRP43 YGL120C RNA helicase in the DEAH-box family physical 1 1 1 Affinity Capture-MS
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Biochemical Activity
RRN3 YKL125W Protein required for transcription of rDNA by RNA polymerase I physical 1 1 1 Reconstituted Complex
RRP43 YCR035C Exosome non-catalytic core component physical 1 1 1 Reconstituted Complex
ORC1 YML065W Largest subunit of the origin recognition complex physical 1 1 1 Affinity Capture-MS
ORC1 YML065W Largest subunit of the origin recognition complex genetic 1 1 1 Negative Genetic
RRP17 YDR412W 5' exoribonuclease required for 5' end processing of pre-60S rRNA physical 1 1 1 Affinity Capture-MS
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
SPB4 YFL002C Putative ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
NUM1 YDR150W Protein required for nuclear migration physical 1 1 1 Two-hybrid
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor physical 1 1 1 Two-hybrid
SSA3 YBL075C ATPase involved in protein folding and the response to stress physical 1 1 1 Two-hybrid
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Two-hybrid
YET3 YDL072C Protein of unknown function physical 1 1 1 Two-hybrid
VBA4 YDR119W Protein of unknown function physical 1 1 1 Two-hybrid
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor physical 1 1 1 Two-hybrid
SSF2 YDR312W Protein required for ribosomal large subunit maturation physical 1 1 1 Two-hybrid
SHE9 YDR393W Protein required for normal mitochondrial morphology physical 1 1 1 Two-hybrid
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 1 1 1 Negative Genetic
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) physical 1 1 1 Two-hybrid
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Positive Genetic
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
SPR3 YGR059W Sporulation-specific homolog of the CDC3/10/11/12 family of genes physical 1 1 1 Two-hybrid
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation physical 1 1 1 Two-hybrid
OTU2 YHL013C Protein of unknown function physical 1 1 1 Two-hybrid
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor physical 1 1 1 Two-hybrid
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Two-hybrid
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation physical 1 1 1 Two-hybrid
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Two-hybrid
REC107 YJR021C Protein involved in early stages of meiotic recombination physical 1 1 1 Two-hybrid
SGM1 YJR134C Protein of unknown function physical 1 1 1 Two-hybrid
SPC42 YKL042W Central plaque component of spindle pole body (SPB) physical 1 1 1 Two-hybrid
STB6 YKL072W Protein that binds Sin3p in a two-hybrid assay physical 1 1 1 Two-hybrid
RSM22 YKL155C Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Two-hybrid
SNF7 YLR025W One of four subunits of the ESCRT-III complex physical 1 1 1 Two-hybrid
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p physical 1 1 1 Two-hybrid
SNN1 YNL086W Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Two-hybrid
TOP1 YOL006C Topoisomerase I physical 1 1 1 Two-hybrid
SGO1 YOR073W Component of the spindle checkpoint physical 1 1 1 Two-hybrid
TEA1 YOR337W Ty1 enhancer activator involved in Ty enhancer-mediated transcription physical 1 1 1 Two-hybrid
SPC29 YPL124W Inner plaque spindle pole body (SPB) component physical 1 1 1 Two-hybrid
YPL216W YPL216W Putative protein of unknown function physical 1 1 1 Two-hybrid
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 1 1 1 Two-hybrid
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Co-purification
RPL11A YPR102C Ribosomal 60S subunit protein L11A physical 1 1 1 Co-purification
RPL11B YGR085C Ribosomal 60S subunit protein L11B physical 1 1 1 Co-purification
RPL12A YEL054C Ribosomal 60S subunit protein L12A physical 1 1 1 Co-purification
RPL12B YDR418W Ribosomal 60S subunit protein L12B physical 1 1 1 Co-purification
RPL13A YDL082W Ribosomal 60S subunit protein L13A physical 1 1 1 Co-purification
RPL13B YMR142C Ribosomal 60S subunit protein L13B physical 1 1 1 Co-purification
RPL14A YKL006W Ribosomal 60S subunit protein L14A physical 1 1 1 Co-purification
RPL14B YHL001W Ribosomal 60S subunit protein L14B physical 1 1 1 Co-purification
RPL15A YLR029C Ribosomal 60S subunit protein L15A physical 1 1 1 Co-purification
RPL15B YMR121C Ribosomal 60S subunit protein L15B physical 1 1 1 Co-purification
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Co-purification
RPL16B YNL069C Ribosomal 60S subunit protein L16B physical 1 1 1 Co-purification
RPL17A YKL180W Ribosomal 60S subunit protein L17A physical 1 1 1 Co-purification
RPL17B YJL177W Ribosomal 60S subunit protein L17B physical 1 1 1 Co-purification
RPL18A YOL120C Ribosomal 60S subunit protein L18A physical 1 1 1 Co-purification
RPL18B YNL301C Ribosomal 60S subunit protein L18B physical 1 1 1 Co-purification
RPL19A YBR084C-A Ribosomal 60S subunit protein L19A physical 1 1 1 Co-purification
RPL19B YBL027W Ribosomal 60S subunit protein L19B physical 1 1 1 Co-purification
RPL19B YBL027W Ribosomal 60S subunit protein L19B genetic 1 1 1 Negative Genetic
RPL1A YPL220W Ribosomal 60S subunit protein L1A physical 1 1 1 Co-purification
RPL1B YGL135W Ribosomal 60S subunit protein L1B physical 1 1 1 Co-purification
RPL20A YMR242C Ribosomal 60S subunit protein L20A physical 1 1 1 Co-purification
RPL20B YOR312C Ribosomal 60S subunit protein L20B physical 1 1 1 Co-purification
RPL21A YBR191W Ribosomal 60S subunit protein L21A physical 1 1 1 Co-purification
RPL21B YPL079W Ribosomal 60S subunit protein L21B physical 1 1 1 Co-purification
RPL22A YLR061W Ribosomal 60S subunit protein L22A physical 1 1 1 Co-purification
RPL22B YFL034C-A Ribosomal 60S subunit protein L22A physical 1 1 1 Co-purification
RPL23A YBL087C Ribosomal 60S subunit protein L23A physical 1 1 1 Co-purification
RPL23B YER117W Ribosomal 60S subunit protein L23B physical 1 1 1 Co-purification
RPL24B YGR148C Ribosomal 60S subunit protein L24B physical 1 1 1 Co-purification
RPL26B YGR034W Ribosomal 60S subunit protein L26B physical 1 1 1 Co-purification
RPL27A YHR010W Ribosomal 60S subunit protein L27A physical 1 1 1 Co-purification
RPL27B YDR471W Ribosomal 60S subunit protein L27B physical 1 1 1 Co-purification
RPL28 YGL103W Ribosomal 60S subunit protein L28 physical 1 1 1 Co-purification
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 physical 1 1 1 Co-purification
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A physical 1 1 1 Co-purification
RPL2B YIL018W Ribosomal 60S subunit protein L2B physical 1 1 1 Co-purification
RPL30 YGL030W Ribosomal 60S subunit protein L30 physical 1 1 1 Co-purification
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Co-purification
RPL31B YLR406C Ribosomal 60S subunit protein L31B physical 1 1 1 Co-purification
RPL32 YBL092W Ribosomal 60S subunit protein L32 physical 1 1 1 Co-purification
RPL33A YPL143W Ribosomal 60S subunit protein L33A physical 1 1 1 Co-purification
RPL33B YOR234C Ribosomal 60S subunit protein L33B physical 1 1 1 Co-purification
RPL34B YIL052C Ribosomal 60S subunit protein L34B physical 1 1 1 Co-purification
RPL35A YDL191W Ribosomal 60S subunit protein L35A physical 1 1 1 Co-purification
RPL35B YDL136W Ribosomal 60S subunit protein L35B physical 1 1 1 Co-purification
RPL36A YMR194W Ribosomal 60S subunit protein L36A physical 1 1 1 Co-purification
RPL36B YPL249C-A Ribosomal 60S subunit protein L36B physical 1 1 1 Co-purification
RPL37A YLR185W Ribosomal 60S subunit protein L37A physical 1 1 1 Co-purification
RPL37B YDR500C Ribosomal 60S subunit protein L37B physical 1 1 1 Co-purification
RPL38 YLR325C Ribosomal 60S subunit protein L38 physical 1 1 1 Co-purification
RPL39 YJL189W Ribosomal 60S subunit protein L39 physical 1 1 1 Co-purification
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein physical 1 1 1 Co-purification
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein physical 1 1 1 Co-purification
RPL41A YDL184C Ribosomal 60S subunit protein L41A physical 1 1 1 Co-purification
RPL41B YDL133C-A Ribosomal 60S subunit protein L41B physical 1 1 1 Co-purification
RPL42A YNL162W Ribosomal 60S subunit protein L42A physical 1 1 1 Co-purification
RPL42B YHR141C Ribosomal 60S subunit protein L42B physical 1 1 1 Co-purification
RPL43A YPR043W Ribosomal 60S subunit protein L43A physical 1 1 1 Co-purification
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B physical 1 1 1 Co-purification
RPL4B YDR012W Ribosomal 60S subunit protein L4B physical 1 1 1 Co-purification
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 1 1 1 Co-purification
RPL6A YML073C Ribosomal 60S subunit protein L6A physical 1 1 1 Co-purification
RPL6B YLR448W Ribosomal 60S subunit protein L6B physical 1 1 1 Co-purification
RPL7A YGL076C Ribosomal 60S subunit protein L7A physical 1 1 1 Co-purification
RPL7B YPL198W Ribosomal 60S subunit protein L7B physical 1 1 1 Co-purification
RPL8A YHL033C Ribosomal 60S subunit protein L8A physical 1 1 1 Co-purification
RPL8B YLL045C Ribosomal 60S subunit protein L8A physical 1 1 1 Co-purification
RPL9A YGL147C Ribosomal 60S subunit protein L9A physical 1 1 1 Co-purification
RPL9B YNL067W Ribosomal 60S subunit protein L9B physical 1 1 1 Co-purification
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RRP45 YDR280W Exosome non-catalytic core component physical 1 1 1 Reconstituted Complex
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
YOS9 YDR057W ER quality-control lectin genetic 1 1 1 Positive Genetic
YJL107C YJL107C Putative protein of unknown function genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
TAF4 YMR005W TFIID subunit (48 kDa) genetic 1 1 1 Negative Genetic
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 1 1 1 Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Negative Genetic
STP1 YDR463W Transcription factor genetic 1 1 1 Negative Genetic
URC2 YDR520C Putative Zn(II)2Cys6 motif containing transcription factor genetic 1 1 1 Negative Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Negative Genetic
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
RCM1 YNL022C rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 1 1 1 Negative Genetic
SKI7 YOR076C GTP-binding protein that couples the Ski complex and exosome genetic 1 1 1 Negative Genetic
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation genetic 1 1 1 Negative Genetic
PKP2 YGL059W Mitochondrial protein kinase genetic 1 1 1 Positive Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Positive Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Positive Genetic
VPS15 YBR097W Serine/threonine protein kinase involved in vacuolar protein sorting genetic 1 1 1 Positive Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Positive Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Positive Genetic
RPC40 YPR110C RNA polymerase subunit AC40 genetic 1 1 1 Positive Genetic
MAS2 YHR024C Alpha subunit of the mitochondrial processing protease (MPP) genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 1 1 1 Biochemical Activity
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Positive Genetic
MDH3 YDL078C Peroxisomal malate dehydrogenase genetic 1 1 1 Positive Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
FAR3 YMR052W Protein of unknown function physical 1 1 1 Two-hybrid
GZF3 YJL110C GATA zinc finger protein genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes physical 1 1 1 Two-hybrid
BLI1 YKL061W Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Two-hybrid
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein physical 1 1 1 Two-hybrid
BRF1 YGR246C TFIIIB B-related factor physical 1 1 1 Affinity Capture-MS
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
MIF2 YKL089W Centromeric CDEIII region binding protein physical 1 1 1 Two-hybrid
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Positive Genetic
IOC2 YLR095C Subunit of the Isw1b complex physical 1 1 1 Two-hybrid
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
BIK1 YCL029C Microtubule-associated protein physical 1 1 1 Two-hybrid
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway physical 1 1 1 Affinity Capture-MS
HRB1 YNL004W Poly(A+) RNA-binding protein genetic 1 1 1 Negative Genetic
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Negative Genetic
MID2 YLR332W O-glycosylated plasma membrane protein genetic 1 1 1 Positive Genetic
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p physical 1 1 1 Two-hybrid
IVY1 YDR229W Phospholipid-binding protein that interacts with both Ypt7p and Vps33p physical 1 1 1 Two-hybrid
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway physical 1 1 1 Two-hybrid
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
COY1 YKL179C Golgi membrane protein with similarity to mammalian CASP physical 1 1 1 Two-hybrid
MET4 YNL103W Leucine-zipper transcriptional activator physical 1 1 1 Two-hybrid
GTA1 YEL043W Protein of unknown function physical 1 1 1 Two-hybrid
ASF2 YDL197C Anti-silencing protein physical 1 1 1 Two-hybrid
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes physical 1 1 1 Two-hybrid
KTR2 YKR061W Mannosyltransferase involved in N-linked protein glycosylation genetic 1 1 1 Negative Genetic
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Positive Genetic
FMP32 YFL046W Regulator of mitochondrial proline metabolism physical 1 1 1 Two-hybrid
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein physical 1 1 1 Affinity Capture-MS
MPP6 YNR024W Nuclear exosome-associated RNA binding protein physical 1 1 1 Reconstituted Complex
BIL1 YOR304C-A Protein that binds Bud6p and has a role in actin cable assembly physical 1 1 1 Two-hybrid
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
MSF1 YPR047W Mitochondrial phenylalanyl-tRNA synthetase genetic 1 1 1 Positive Genetic
FCY1 YPR062W Cytosine deaminase genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
DIA1 YMR316W Protein of unknown function genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Positive Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA physical 1 1 1 Affinity Capture-MS
MTC2 YKL098W Protein of unknown function genetic 1 1 1 Negative Genetic
MIX23 YBL107C Mitochondrial intermembrane space protein of unknown function genetic 1 1 1 Negative Genetic
ARR1 YPR199C Transcriptional activator of the basic leucine zipper (bZIP) family physical 1 1 1 Two-hybrid
EMC3 YKL207W Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Positive Genetic
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum physical 1 1 1 Two-hybrid
MOD5 YOR274W Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase genetic 1 1 1 Negative Genetic
NMA111 YNL123W Serine protease and general molecular chaperone genetic 1 1 1 Positive Genetic
HMI1 YOL095C Mitochondrial inner membrane localized ATP-dependent DNA helicase genetic 1 1 1 Negative Genetic