| RAD10 |
YML095C |
Single-stranded DNA endonuclease (with Rad1p) |
physical |
25 |
6 |
16 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Co-fractionation, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Co-purification, Co-fractionation, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western |
| SAW1 |
YAL027W |
5'- and 3'-flap DNA binding protein |
physical |
19 |
7 |
10 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Far Western, Affinity Capture-Western, Co-purification, Co-fractionation, Reconstituted Complex, Affinity Capture-Western |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
18 |
4 |
17 |
Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Positive Genetic |
| APN1 |
YKL114C |
Major apurinic/apyrimidinic endonuclease |
genetic |
12 |
4 |
10 |
Synthetic Growth Defect, Synthetic Lethality, Phenotypic Enhancement, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
8 |
4 |
8 |
Synthetic Growth Defect, Negative Genetic, Phenotypic Suppression, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
8 |
3 |
7 |
Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Enhancement, Synthetic Growth Defect |
| RAD18 |
YCR066W |
E3 ubiquitin ligase |
genetic |
7 |
3 |
7 |
Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| APN2 |
YBL019W |
Class II abasic (AP) endonuclease involved in repair of DNA damage |
genetic |
7 |
2 |
7 |
Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality |
| TDP1 |
YBR223C |
Tyrosyl-DNA phosphodiesterase I |
genetic |
7 |
3 |
6 |
Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Lethality, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| REV3 |
YPL167C |
Catalytic subunit of DNA polymerase zeta |
genetic |
7 |
3 |
6 |
Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Enhancement |
| SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
physical |
7 |
2 |
6 |
Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western |
| RAD14 |
YMR201C |
Subunit of Nucleotide Excision Repair Factor 1 (NEF1) |
physical |
7 |
4 |
5 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-fractionation, Reconstituted Complex, Affinity Capture-Western |
| RAD59 |
YDL059C |
Protein involved DNA double-strand break repair |
genetic |
5 |
3 |
5 |
Phenotypic Suppression, Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect |
| RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
5 |
2 |
5 |
Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| MUS81 |
YDR386W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
5 |
2 |
5 |
Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect |
| RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
4 |
3 |
4 |
Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
4 |
3 |
4 |
Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
4 |
2 |
4 |
Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Positive Genetic |
| NTG1 |
YAL015C |
DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement |
| NTG2 |
YOL043C |
DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement |
| TOP3 |
YLR234W |
DNA Topoisomerase III |
genetic |
3 |
3 |
3 |
Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic |
| RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
3 |
3 |
3 |
Phenotypic Suppression, Phenotypic Enhancement, Synthetic Lethality |
| POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
3 |
3 |
3 |
Positive Genetic, Synthetic Growth Defect, Negative Genetic |
| RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Phenotypic Enhancement, Phenotypic Enhancement |
| EXO1 |
YOR033C |
5'-3' exonuclease and flap-endonuclease |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Enhancement |
| MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
genetic |
3 |
1 |
3 |
Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement |
| MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
3 |
3 |
2 |
Phenotypic Enhancement, Synthetic Lethality, Phenotypic Suppression |
| RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
3 |
3 |
2 |
Synthetic Lethality, Phenotypic Enhancement, Synthetic Growth Defect |
| TPP1 |
YMR156C |
DNA 3'-phosphatase |
genetic |
3 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
physical |
2 |
2 |
2 |
Two-hybrid, Far Western |
| MPH1 |
YIR002C |
3'-5' DNA helicase involved in error-free bypass of DNA lesions |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Synthetic Growth Defect |
| MSH3 |
YCR092C |
Mismatch repair protein |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Dosage Lethality |
| RAD17 |
YOR368W |
Checkpoint protein |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Synthetic Rescue |
| SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Synthetic Growth Defect |
| SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
| RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect |
| RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| YEN1 |
YER041W |
Holliday junction resolvase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Enhancement |
| RNH201 |
YNL072W |
Ribonuclease H2 catalytic subunit |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Synthetic Rescue |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Growth Defect |
| MMS2 |
YGL087C |
Ubiquitin-conjugating enzyme variant |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Suppression |
| DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| MAG1 |
YER142C |
3-methyl-adenine DNA glycosylase |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect |
| MMS4 |
YBR098W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Synthetic Growth Defect |
| MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Synthetic Lethality |
| POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Enhancement |
| MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
| YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
genetic |
2 |
1 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UNG1 |
YML021C |
Uracil-DNA glycosylase |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| MGL2 |
YMR210W |
Monoacylglycerol and triacylglycerol lipase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PMS1 |
YNL082W |
ATP-binding protein required for mismatch repair |
genetic |
2 |
1 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement |
| CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Negative Genetic |
| COQ3 |
YOL096C |
O-methyltransferase |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Synthetic Rescue |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF3 |
YLR381W |
Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM22 |
YJR135C |
Outer kinetochore protein and component of the Ctf3 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS21 |
YEL019C |
Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE1 |
YLR007W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP9 |
YLR276C |
DEAD-box protein required for 27S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC42 |
YLR229C |
Small rho-like GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NHP2 |
YDL208W |
Protein related to mammalian high mobility group (HMG) proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIS3 |
YOL021C |
Exosome core complex catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP82 |
YJL061W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APC2 |
YLR127C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AIM21 |
YIR003W |
Subunit of a complex that associates with actin filaments |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| DBP10 |
YDL031W |
Putative ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HSM3 |
YBR272C |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRR1 |
YIL026C |
Subunit of the cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MAS1 |
YLR163C |
Beta subunit of the mitochondrial processing protease (MPP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MLH1 |
YMR167W |
Protein required for mismatch repair in mitosis and meiosis |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRPL35 |
YDR322W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL8 |
YJL063C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSH3 |
YCR092C |
Mismatch repair protein |
physical |
1 |
1 |
1 |
Far Western |
| MSH6 |
YDR097C |
Protein required for mismatch repair in mitosis and meiosis |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MTR10 |
YOR160W |
Nuclear import receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP114 |
YGL241W |
Karyopherin, responsible for nuclear import of specific proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP28 |
YDR243C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEP4 |
YPL154C |
Vacuolar aspartyl protease (proteinase A) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| MRPL6 |
YHR147C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CRN1 |
YLR429W |
Coronin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAW1 |
YAL027W |
5'- and 3'-flap DNA binding protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC6 |
YIL068C |
Essential 88kDa subunit of the exocyst complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YHR033W |
YHR033W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBI4 |
YLL039C |
Ubiquitin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UTP4 |
YDR324C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UTP4 |
YDR324C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD10 |
YML095C |
Single-stranded DNA endonuclease (with Rad1p) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RAD17 |
YOR368W |
Checkpoint protein |
physical |
1 |
1 |
1 |
Co-purification |
| YCR087C-A |
YCR087C-A |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT10 |
YPL183C |
WD40 domain-containing protein involved in endosomal recycling |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIZ1 |
YDR409W |
SUMO E3 ligase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REC8 |
YPR007C |
Meiosis-specific component of the sister chromatid cohesion complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| RAD30 |
YDR419W |
DNA polymerase eta |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| VMA6 |
YLR447C |
Subunit d of the V0 integral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VID24 |
YBR105C |
GID Complex regulatory subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YFH1 |
YDL120W |
Mitochondrial matrix iron chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAS4 |
YDR181C |
Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNH202 |
YDR279W |
Ribonuclease H2 subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD2 |
YGR258C |
Single-stranded DNA endonuclease |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| UBC8 |
YEL012W |
Ubiquitin-conjugating enzyme that regulates gluconeogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SGD1 |
YLR336C |
Essential nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| UBC9 |
YDL064W |
SUMO-conjugating enzyme involved in the Smt3p conjugation pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SLX1 |
YBR228W |
Endonuclease involved in DNA recombination and repair |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| SML1 |
YML058W |
Ribonucleotide reductase inhibitor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| RAD24 |
YER173W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RNA14 |
YMR061W |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SPP381 |
YBR152W |
mRNA splicing factor, component of U4/U6.U5 tri-snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRP42 |
YDL111C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRP45 |
YDR280W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAH11 |
YJR046W |
DNA replication licensing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRN9 |
YMR270C |
Protein involved in promoting high level transcription of rDNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YGR035C |
YGR035C |
Putative protein of unknown function, potential Cdc28p substrate |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIF2 |
YJL138C |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMT1 |
YJL147C |
Translational repressor of the mitochondrial ATP6/8 mRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YEH2 |
YLR020C |
Steryl ester hydrolase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YMR226C |
YMR226C |
NADP(+)-dependent serine dehydrogenase and carbonyl reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YNL035C |
YNL035C |
Nuclear protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLM2 |
YNL047C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YOL029C |
YOL029C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMF1 |
YOL122C |
Divalent metal ion transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YOL155W-A |
YOL155W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIB7 |
YBR153W |
Diaminohydroxyphoshoribosylaminopyrimidine deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSR1 |
YDL060W |
Protein required for processing of 20S pre-rRNA in the cytoplasm |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAS10 |
YDL153C |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC19 |
YDR201W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNU13 |
YEL026W |
RNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC3 |
YER008C |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCC4 |
YER147C |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| USE1 |
YGL098W |
Essential SNARE protein localized to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUA5 |
YGL169W |
Protein involved in threonylcarbamoyl adenosine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VHT1 |
YGR065C |
High-affinity plasma membrane H+-biotin (vitamin H) symporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPP1 |
YGR198W |
Cargo-transport protein involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP1 |
YHR062C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP4 |
YHR069C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN7 |
YJL025W |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP14 |
YKL082C |
Essential protein, constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT4 |
YLR305C |
Phosphatidylinositol-4-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN11 |
YML043C |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRB1 |
YMR131C |
Specific assembly chaperone for ribosomal protein Rpl3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC98 |
YNL126W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC31 |
YNL151C |
RNA polymerase III subunit C31 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIB2 |
YOL066C |
Bifunctional DRAP deaminase tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UFE1 |
YOR075W |
t-SNARE protein required for retrograde vesicular traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RKI1 |
YOR095C |
Ribose-5-phosphate ketol-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOG2 |
YOR353C |
Key component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAL064W |
YAL064W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TYR1 |
YBR166C |
Prephenate dehydrogenase involved in tyrosine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL124W |
YDL124W |
NADPH-dependent alpha-keto amide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL129W |
YDL129W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP1B |
YDL130W |
Ribosomal protein P1 beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR034W-B |
YDR034W-B |
Predicted tail-anchored plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STB3 |
YDR169C |
Ribosomal RNA processing element (RRPE)-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR249C |
YDR249C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YSP2 |
YDR326C |
Sterol-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDH6 |
YDR379C-A |
Mitochondrial protein involved in assembly of succinate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOM1 |
YEL059C-A |
Subunit of the mitochondrial inner membrane peptidase (IMP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS8B |
YER102W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER134C |
YER134C |
Magnesium-dependent acid phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER152C |
YER152C |
Protein with 2-aminoadipate transaminase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPH1 |
YER169W |
JmjC domain-containing histone demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YFR006W |
YFR006W |
Putative X-Pro aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YFH7 |
YFR007W |
Putative kinase with similarity to the PRK/URK/PANK kinase subfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPN1 |
YGL186C |
Plasma membrane pyridoxine (vitamin B6) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR111W |
YGR111W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR130C |
YGR130C |
Component of the eisosome with unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THI4 |
YGR144W |
Thiazole synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR153W |
YGR153W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR210C |
YGR210C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLH1 |
YGR271W |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSP1 |
YHR184W |
Protein involved in the control of meiotic nuclear division |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR210C |
YHR210C |
Putative aldose 1-epimerase superfamily protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPS6 |
YIR039C |
Putative GPI-anchored aspartic protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS55 |
YJR044C |
Late endosomal protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR115W |
YJR115W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UFD4 |
YKL010C |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STE6 |
YKL209C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VBA5 |
YKR105C |
Plasma membrane protein of the Major Facilitator Superfamily (MFS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPS1 |
YLR120C |
Aspartic protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UPS2 |
YLR168C |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR264C-A |
YLR264C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSO55 |
YLR281C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR412C-A |
YLR412C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR464W |
YLR464W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML108W |
YML108W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR084W |
YMR084W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL15B |
YMR121C |
Ribosomal 60S subunit protein L15B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR262W |
YMR262W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRG9 |
YNL213C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOL019W-A |
YOL019W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOL131W |
YOL131W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOL162W |
YOL162W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR292C |
YOR292C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAX1 |
YOR301W |
Protein involved in establishing bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEA1 |
YOR337W |
Ty1 enhancer activator involved in Ty enhancer-mediated transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIP4 |
YJL089W |
C6 zinc cluster transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT23 |
YKL020C |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNH1 |
YMR234W |
Ribonuclease H1 |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBP12 |
YJL197W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIR2 |
YOR356W |
Putative ortholog of human ETF-dH |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CAR2 |
YLR438W |
L-ornithine transaminase (OTAse) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LSP1 |
YPL004C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DMA2 |
YNL116W |
Ubiquitin-protein ligase (E3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HTB1 |
YDR224C |
Histone H2B |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| AHP1 |
YLR109W |
Thiol-specific peroxiredoxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GSP2 |
YOR185C |
GTP binding protein (mammalian Ranp homolog) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV5 |
YLR355C |
Acetohydroxyacid reductoisomerase and mtDNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KOG1 |
YHR186C |
Subunit of TORC1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| GYP6 |
YJL044C |
GTPase-activating protein (GAP) for yeast Rab family member Ypt6p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPD2 |
YOL059W |
NAD-dependent glycerol 3-phosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MDM30 |
YLR368W |
F-box component of an SCF ubiquitin protein ligase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPD1 |
YDL022W |
NAD-dependent glycerol-3-phosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FAR1 |
YJL157C |
CDK inhibitor and nuclear anchor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PDC6 |
YGR087C |
Minor isoform of pyruvate decarboxylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG42 |
YBR139W |
Vacuolar serine-type carboxypeptidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DDC1 |
YPL194W |
DNA damage checkpoint protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOP1 |
YDR141C |
Protein involved in vesicular transport at trans-Golgi network (TGN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDS1 |
YDR113C |
Securin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ERG1 |
YGR175C |
Squalene epoxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GLE1 |
YDL207W |
Cytoplasmic nucleoporin required for polyadenylated mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAL7 |
YBR018C |
Galactose-1-phosphate uridyl transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| CHS1 |
YNL192W |
Chitin synthase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHT1 |
YBR010W |
Histone H3 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCK2 |
YER167W |
Serine/threonine-rich protein involved in PKC1 signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCE1 |
YKL011C |
Mitochondrial cruciform cutting endonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OMS1 |
YDR316W |
Protein integral to the mitochondrial membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AHC1 |
YOR023C |
Subunit of the Ada histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP53 |
YPL146C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| DUT1 |
YBR252W |
Deoxyuridine triphosphate diphosphatase (dUTPase) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MIC19 |
YFR011C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MEC3 |
YLR288C |
DNA damage and meiotic pachytene checkpoint protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APE3 |
YBR286W |
Vacuolar aminopeptidase Y |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| JJJ1 |
YNL227C |
Co-chaperone that stimulates the ATPase activity of Ssa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSO2 |
YMR137C |
Nuclease required for DNA single- and double-strand break repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KKQ8 |
YKL168C |
Putative serine/threonine protein kinase with unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCK1 |
YLR422W |
Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BIT2 |
YBR270C |
Subunit of TORC2 membrane-associated complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARH1 |
YDR376W |
Oxidoreductase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUP2 |
YGL166W |
Copper-binding transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC24 |
YLR323C |
General splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIT61 |
YJL058C |
Subunit of TORC2 membrane-associated complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRM3 |
YPL192C |
Protein required for nuclear envelope fusion during karyogamy |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX14 |
YGL153W |
Central component of the peroxisomal importomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NFI1 |
YOR156C |
SUMO E3 ligase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP150 |
YJL159W |
O-mannosylated heat shock protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAM18 |
YLR008C |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMC1 |
YCL045C |
Member of conserved endoplasmic reticulum membrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| BCH1 |
YMR237W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMR2 |
YOR093C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRI1 |
YLR301W |
Protein of unknown function that interacts with Sec72p and Hrr25p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRF1 |
YGL143C |
Mitochondrial translation release factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCA1 |
YOR197W |
Ca2+-dependent cysteine protease |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHT2 |
YNL031C |
Histone H3 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PAN3 |
YKL025C |
Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATM1 |
YMR301C |
Mitochondrial inner membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAF1 |
YIL019W |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF6 |
YJR082C |
Subunit of the NuA4 acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MHP1 |
YJL042W |
Microtubule-associated protein involved in microtubule organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADI1 |
YMR009W |
Acireductone dioxygenease involved in methionine salvage pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ9 |
YLR201C |
Protein required for ubiquinone biosynthesis and respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESBP6 |
YNL125C |
Protein with similarity to monocarboxylate permeases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CFD1 |
YIL003W |
Highly conserved iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BTT1 |
YDR252W |
Heterotrimeric nascent polypeptide-associated complex beta3 subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG7 |
YHR072W |
Lanosterol synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTO1 |
YPR031W |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF4 |
YGL014W |
Member of the PUF protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NKP2 |
YLR315W |
Central kinetochore protein and subunit of the Ctf19 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GRE3 |
YHR104W |
Aldose reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDR10 |
YOR328W |
ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OLE1 |
YGL055W |
Delta(9) fatty acid desaturase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSS51 |
YLR203C |
Specific translational activator for the mitochondrial COX1 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCY1 |
YGR012W |
Putative cysteine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NVJ3 |
YDR179W-A |
Protein with a potential role in tethering ER and vacuoles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HEM1 |
YDR232W |
5-aminolevulinate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG21 |
YPL100W |
Phosphoinositide binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HXT10 |
YFL011W |
Hexose transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRE8 |
YLR047C |
Protein with sequence similarity to iron/copper reductases |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAS3 |
YMR215W |
Putative 1,3-beta-glucanosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRM10 |
YJL108C |
Pheromone-regulated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAP2 |
YHR028C |
Dipeptidyl aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAN5 |
YHR063C |
2-dehydropantoate 2-reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ALG13 |
YGL047W |
Catalytic component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KTR1 |
YOR099W |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HVG1 |
YER039C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COQ2 |
YNR041C |
Para hydroxybenzoate polyprenyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| JJJ3 |
YJR097W |
Iron-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET7 |
YOR241W |
Folylpolyglutamate synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AST2 |
YER101C |
Lipid raft associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENA5 |
YDR038C |
Protein with similarity to P-type ATPase sodium pumps |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ECM13 |
YBL043W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERG4 |
YGL012W |
C-24(28) sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BSC1 |
YDL037C |
Protein of unconfirmed function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRN1 |
YPL184C |
RNA-binding protein that may be involved in translational regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NNR2 |
YKL151C |
Widely-conserved NADHX dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DSE2 |
YHR143W |
Daughter cell-specific secreted protein with similarity to glucanases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAN4 |
YJR151C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFG10 |
YIL049W |
Probable polyprenol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FLO9 |
YAL063C |
Lectin-like protein with similarity to Flo1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EDS1 |
YBR033W |
Putative zinc cluster protein, predicted to be a transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX4 |
YGR133W |
Peroxisomal ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPC3 |
YGR243W |
Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IFM1 |
YOL023W |
Mitochondrial translation initiation factor 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPL1 |
YDR294C |
Dihydrosphingosine phosphate lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCC2 |
YDR270W |
Cu(+2)-transporting P-type ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMI7 |
YIL002W-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IGO2 |
YHR132W-A |
Protein required for initiation of G0 program |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIC27 |
YNL100W |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM4 |
YKR076W |
S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSC1 |
YML128C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCH4 |
YOL119C |
Protein with similarity to mammalian monocarboxylate permeases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPI8 |
YJL133C-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX16 |
YJL003W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMC3 |
YKL207W |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ICY1 |
YMR195W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DLT1 |
YMR126C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HMX1 |
YLR205C |
ER localized heme oxygenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATR2 |
YMR279C |
Putative boron transporter involved in boron efflux and resistance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATX2 |
YOR079C |
Golgi membrane protein involved in manganese homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIF1 |
YML061C |
DNA helicase, potent G-quadruplex DNA binder/unwinder |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| BCD1 |
YHR040W |
Essential protein required for the accumulation of box C/D snoRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FSH2 |
YMR222C |
Putative serine hydrolase that localizes to the cytoplasm |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MNT3 |
YIL014W |
Alpha-1,3-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX10 |
YDR282C |
Mitochondrial inner membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LRE1 |
YCL051W |
Protein involved in control of cell wall structure and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MME1 |
YMR166C |
Transporter of the mitochondrial inner membrane that exports magnesium |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRY3 |
YJL078C |
GPI-anchored cell wall protein involved in export of sterols |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAU24 |
YBR301W |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Positive Genetic |
