Standard name Systematic name Name description Description
UBP12 YJL197W Ubiquitin-specific protease Ubiquitin-specific protease; cleaves ubiquitin from ubiquitinated proteins; present in the nucleus and cytoplasm
Visualize the interactome of UBP12
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleus 0.863 0.814 0.871
Vac/Vac Memb 0.143 0.213 0.062
Mito NaN NaN 0.114

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 7110

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
UBP12 3 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 3 1 2 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 2 2 2 Negative Genetic, Synthetic Rescue
RAD52 YML032C Protein involved in homologous recombination genetic 2 2 2 Negative Genetic, Phenotypic Suppression
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 2 1 2 Negative Genetic, Negative Genetic
UBP2 YOR124C Ubiquitin-specific protease regulation 2 2 1 co-immunoprecipitation evidence, qualitative western immunoblotting evidence
RAD23 YEL037C Protein with ubiquitin-like N terminus physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion regulation 1 1 1 qualitative western immunoblotting evidence
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) regulation 1 1 1 immunodetection assay evidence
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Positive Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
RPC40 YPR110C RNA polymerase subunit AC40 genetic 1 1 1 Negative Genetic
PSY2 YNL201C Subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme genetic 1 1 1 Negative Genetic
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
ERG26 YGL001C C-3 sterol dehydrogenase genetic 1 1 1 Negative Genetic
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Phenotypic Suppression
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Dosage Growth Defect
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Negative Genetic
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Negative Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Negative Genetic
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint genetic 1 1 1 Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Synthetic Growth Defect
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Positive Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
ABF2 YMR072W Mitochondrial DNA-binding protein genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
CIR2 YOR356W Putative ortholog of human ETF-dH genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Negative Genetic
FKH1 YIL131C Forkhead family transcription factor physical 1 1 1 Affinity Capture-MS
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 1 1 1 Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Negative Genetic
PDI1 YCL043C Protein disulfide isomerase genetic 1 1 1 Negative Genetic
PDS1 YDR113C Securin physical 1 1 1 Biochemical Activity
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin physical 1 1 1 Biochemical Activity
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) physical 1 1 1 Affinity Capture-Western
PPE1 YHR075C Protein with carboxyl methyl esterase activity genetic 1 1 1 Negative Genetic
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Negative Genetic
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion physical 1 1 1 Affinity Capture-Western
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
CPR3 YML078W Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Positive Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Negative Genetic
GPA1 YHR005C Subunit of G protein involved in pheromone response physical 1 1 1 Affinity Capture-Western
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Negative Genetic
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Positive Genetic
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
CPR2 YHR057C Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
SHU1 YHL006C Component of Shu complex (aka PCSS complex) genetic 1 1 1 Negative Genetic
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
DOC1 YGL240W Processivity factor genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Positive Genetic
SAC3 YDR159W mRNA export factor physical 1 1 1 Affinity Capture-MS
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 1 1 1 Negative Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
FRQ1 YDR373W N-myristoylated calcium-binding protein genetic 1 1 1 Negative Genetic
GEA1 YJR031C Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) physical 1 1 1 Affinity Capture-MS
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 1 1 1 Negative Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
ARG80 YMR042W Transcription factor involved in regulating arginine-responsive genes genetic 1 1 1 Negative Genetic
MET32 YDR253C Zinc-finger DNA-binding transcription factor genetic 1 1 1 Negative Genetic
AZF1 YOR113W Zinc-finger transcription factor genetic 1 1 1 Negative Genetic
REV3 YPL167C Catalytic subunit of DNA polymerase zeta genetic 1 1 1 Phenotypic Suppression
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
PRS4 YBL068W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP genetic 1 1 1 Negative Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
PLP1 YDR183W Protein that interacts with CCT (chaperonin containing TCP-1) complex genetic 1 1 1 Negative Genetic
JHD2 YJR119C JmjC domain family histone demethylase genetic 1 1 1 Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties genetic 1 1 1 Phenotypic Enhancement
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Positive Genetic
DPH5 YLR172C Methyltransferase required for synthesis of diphthamide genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
SGO1 YOR073W Component of the spindle checkpoint genetic 1 1 1 Negative Genetic
PNP1 YLR209C Purine nucleoside phosphorylase genetic 1 1 1 Negative Genetic
EAR1 YMR171C Specificity factor required for Rsp5p-dependent ubiquitination genetic 1 1 1 Negative Genetic
BXI1 YNL305C Protein involved in apoptosis genetic 1 1 1 Negative Genetic
PTR2 YKR093W Integral membrane peptide transporter genetic 1 1 1 Negative Genetic
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
LCB4 YOR171C Sphingoid long-chain base kinase genetic 1 1 1 Negative Genetic
MUP3 YHL036W Low affinity methionine permease genetic 1 1 1 Negative Genetic
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 genetic 1 1 1 Negative Genetic
TDA5 YLR426W Putative protein of unknown function genetic 1 1 1 Negative Genetic
PHO5 YBR093C Repressible acid phosphatase genetic 1 1 1 Negative Genetic
PKP1 YIL042C Mitochondrial protein kinase genetic 1 1 1 Negative Genetic
AIM33 YML087C Protein of unknown function, highly conserved across species genetic 1 1 1 Positive Genetic
BNA4 YBL098W Kynurenine 3-monooxygenase genetic 1 1 1 Negative Genetic
PUT2 YHR037W Delta-1-pyrroline-5-carboxylate dehydrogenase genetic 1 1 1 Negative Genetic
OCT1 YKL134C Mitochondrial intermediate peptidase genetic 1 1 1 Negative Genetic
TOP3 YLR234W DNA Topoisomerase III genetic 1 1 1 Negative Genetic
TSC10 YBR265W 3-ketosphinganine reductase genetic 1 1 1 Negative Genetic
AGP3 YFL055W Low-affinity amino acid permease genetic 1 1 1 Negative Genetic
UBP2 YOR124C Ubiquitin-specific protease physical 1 1 1 Affinity Capture-Western
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Negative Genetic
YJR096W YJR096W Xylose and arabinose reductase genetic 1 1 1 Negative Genetic
URA1 YKL216W Dihydroorotate dehydrogenase genetic 1 1 1 Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Negative Genetic
YPT32 YGL210W Rab family GTPase involved in the exocytic pathway genetic 1 1 1 Negative Genetic
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Negative Genetic
YIM1 YMR152W Aldehyde reductase genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Negative Genetic
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Negative Genetic
YPT31 YER031C Rab family GTPase genetic 1 1 1 Negative Genetic