Standard name Systematic name Name description Description
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) Beta' regulatory subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerase
Visualize the interactome of CKB2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 4

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.109 NaN 0.091
Nucleolus 0.055 0.158 NaN
Nucleus 0.673 0.500 0.773
Vac/Vac Memb 0.218 0.500 0.205

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 7160

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CKB2 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 17 5 14 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS, PCA, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Co-purification
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 15 4 12 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS, PCA, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 11 3 8 Phenotypic Enhancement, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Rescue, Positive Genetic, Positive Genetic
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 10 1 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) physical 9 3 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS, Two-hybrid, Two-hybrid
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 7 2 7 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 7 2 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription physical 7 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
YPT6 YLR262C Rab family GTPase genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 6 2 6 Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UTP22 YGR090W Component of the small-subunit processome physical 6 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 5 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 5 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 5 2 3 Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 5 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 5 2 3 Positive Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RSA3 YLR221C Protein with a likely role in ribosomal maturation genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HOT1 YMR172W Transcription factor for glycerol biosynthetic genes physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 4 1 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes physical 3 2 3 Affinity Capture-Western, Two-hybrid, Two-hybrid
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 3 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SSD1 YDR293C Translational repressor genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SYS1 YJL004C Integral membrane protein of the Golgi genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CAB3 YKL088W Subunit of PPCDC and CoA-SPC complexes involved in CoA biosynthesis physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
BEM1 YBR200W Protein containing SH3-domains genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SPT15 YER148W TATA-binding protein (TBP) physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
MIF2 YKL089W Centromeric CDEIII region binding protein physical 2 2 2 Two-hybrid, Affinity Capture-MS
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RAD53 YPL153C DNA damage response kinase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 2 2 2 Synthetic Lethality, Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 2 2 Synthetic Rescue, Positive Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSA4 YER103W Heat shock protein that is highly induced upon stress physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain physical 2 1 2 Reconstituted Complex, Reconstituted Complex
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 2 Negative Genetic, Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 2 1 2 Negative Genetic, Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 2 1 2 Negative Genetic, Negative Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 2 1 2 Negative Genetic, Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 2 1 2 Negative Genetic, Negative Genetic
MMS4 YBR098W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 2 1 2 Negative Genetic, Negative Genetic
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit genetic 2 1 2 Negative Genetic, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
SAE2 YGL175C Endonuclease required for telomere elongation genetic 2 1 2 Negative Genetic, Negative Genetic
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 2 1 2 Negative Genetic, Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 2 1 2 Positive Genetic, Positive Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 2 1 2 Negative Genetic, Negative Genetic
IRS4 YKR019C EH domain-containing protein genetic 2 1 2 Negative Genetic, Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 2 1 2 Positive Genetic, Positive Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 1 2 Positive Genetic, Positive Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 2 1 2 Negative Genetic, Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 2 1 2 Negative Genetic, Negative Genetic
VPS45 YGL095C Protein of the Sec1p/Munc-18 family genetic 2 1 2 Negative Genetic, Negative Genetic
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 2 1 2 Negative Genetic, Negative Genetic
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 2 1 2 Negative Genetic, Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 2 1 2 Negative Genetic, Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 2 1 2 Negative Genetic, Negative Genetic
CPR8 YNR028W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 2 1 2 Negative Genetic, Negative Genetic
SND1 YDR186C Protein involved in SRP-independent targeting of substrates to the ER genetic 2 1 2 Negative Genetic, Negative Genetic
MIC19 YFR011C Component of the MICOS complex genetic 2 1 2 Negative Genetic, Negative Genetic
DSD1 YGL196W D-serine dehydratase (aka D-serine ammonia-lyase) genetic 2 1 2 Negative Genetic, Negative Genetic
YJL163C YJL163C Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 2 1 2 Negative Genetic, Negative Genetic
SKA1 YKL023W SKI complex-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
UBP11 YKR098C Ubiquitin-specific protease genetic 2 1 2 Negative Genetic, Negative Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 2 1 2 Negative Genetic, Negative Genetic
FMP30 YPL103C Protein with a role in maintaining mitochondrial morphology genetic 2 1 2 Negative Genetic, Negative Genetic
MRX11 YPL041C Protein that associates with mitochondrial ribosome genetic 2 1 2 Negative Genetic, Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 2 1 2 Negative Genetic, Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 2 1 2 Negative Genetic, Negative Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 2 1 2 Negative Genetic, Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 2 1 2 Negative Genetic, Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 2 1 2 Positive Genetic, Positive Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 2 Negative Genetic, Negative Genetic
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 2 1 2 Negative Genetic, Negative Genetic
CAM1 YPL048W One of two isoforms of the gamma subunit of eEF1B genetic 2 1 2 Negative Genetic, Negative Genetic
AAD4 YDL243C Putative aryl-alcohol dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 2 2 1 Positive Genetic, Negative Genetic
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
DFM1 YDR411C Endoplasmic reticulum (ER) localized protein genetic 2 1 1 Negative Genetic, Negative Genetic
DPC29 YGR021W Putative mitochondrial protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 2 1 1 Negative Genetic, Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 2 1 1 Negative Genetic, Negative Genetic
IOC4 YMR044W Member of a complex (Isw1b) with Isw1p and Ioc2p genetic 2 1 1 Negative Genetic, Negative Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 2 1 1 Positive Genetic, Positive Genetic
NPL3 YDR432W RNA-binding protein genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 2 1 1 Negative Genetic, Negative Genetic
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway genetic 2 1 1 Negative Genetic, Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 2 1 1 Negative Genetic, Negative Genetic
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 1 Negative Genetic, Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 2 1 1 Negative Genetic, Negative Genetic
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 2 1 1 Negative Genetic, Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 2 1 1 Negative Genetic, Negative Genetic
YIP1 YGR172C Integral membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 2 1 1 Negative Genetic, Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 2 1 1 Negative Genetic, Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 2 1 1 Negative Genetic, Negative Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 2 1 1 Negative Genetic, Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 2 1 1 Negative Genetic, Negative Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 2 1 1 Negative Genetic, Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 2 1 1 Negative Genetic, Negative Genetic
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 2 1 1 Negative Genetic, Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Negative Genetic, Negative Genetic
SMT1 YJL147C Translational repressor of the mitochondrial ATP6/8 mRNA genetic 2 1 1 Negative Genetic, Negative Genetic
ARF1 YDL192W ADP-ribosylation factor genetic 2 1 1 Positive Genetic, Positive Genetic
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 2 1 1 Negative Genetic, Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 2 1 1 Negative Genetic, Negative Genetic
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) genetic 2 1 1 Negative Genetic, Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex physical 1 1 1 Affinity Capture-MS
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Negative Genetic
CDC40 YDR364C Pre-mRNA splicing factor genetic 1 1 1 Negative Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Phenotypic Suppression
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
TIF35 YDR429C eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes physical 1 1 1 Affinity Capture-MS
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
FKH1 YIL131C Forkhead family transcription factor physical 1 1 1 Affinity Capture-MS
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation physical 1 1 1 Affinity Capture-MS
NOP7 YGR103W Component of several different pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain physical 1 1 1 Affinity Capture-MS
CPA1 YOR303W Small subunit of carbamoyl phosphate synthetase physical 1 1 1 Two-hybrid
FZF1 YGL254W Transcription factor involved in sulfite metabolism physical 1 1 1 Two-hybrid
LSM4 YER112W Lsm (Like Sm) protein physical 1 1 1 Two-hybrid
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin physical 1 1 1 Affinity Capture-Western
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription physical 1 1 1 Affinity Capture-Western
SVF1 YDR346C Protein with a potential role in cell survival pathways physical 1 1 1 Affinity Capture-Western
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RRP36 YOR287C Component of 90S preribosomes physical 1 1 1 Affinity Capture-MS
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity physical 1 1 1 Affinity Capture-MS
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 1 1 1 Affinity Capture-MS
ORC1 YML065W Largest subunit of the origin recognition complex physical 1 1 1 Affinity Capture-MS
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
YCF1 YDR135C Vacuolar glutathione S-conjugate transporter physical 1 1 1 Affinity Capture-Western
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
HTB1 YDR224C Histone H2B physical 1 1 1 Affinity Capture-MS
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
HTB2 YBL002W Histone H2B genetic 1 1 1 Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation genetic 1 1 1 Negative Genetic
SPT23 YKL020C ER membrane protein involved in regulation of OLE1 transcription physical 1 1 1 Affinity Capture-Western
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Affinity Capture-Western
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
HSF1 YGL073W Trimeric heat shock transcription factor physical 1 1 1 Two-hybrid
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP genetic 1 1 1 Negative Genetic
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
SPT6 YGR116W Nucleosome remodeling protein physical 1 1 1 Reconstituted Complex
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Positive Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Phenotypic Enhancement
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Synthetic Lethality
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 1 1 1 Negative Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 1 1 1 Negative Genetic
RAD3 YER171W 5' to 3' DNA helicase genetic 1 1 1 Negative Genetic
RPC40 YPR110C RNA polymerase subunit AC40 genetic 1 1 1 Negative Genetic
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 1 1 1 Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Negative Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p genetic 1 1 1 Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
YOR338W YOR338W Putative protein of unknown function genetic 1 1 1 Phenotypic Suppression
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
SAS4 YDR181C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 1 1 1 Negative Genetic
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
CLB1 YGR108W B-type cyclin involved in cell cycle progression genetic 1 1 1 Negative Genetic
THP1 YOL072W Nuclear pore-associated protein genetic 1 1 1 Negative Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Positive Genetic
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Positive Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Positive Genetic
PLM2 YDR501W Putative transcription factor, contains Forkhead Associated domain genetic 1 1 1 Positive Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Negative Genetic
RRP7 YCL031C Essential protein involved in rRNA processing and ribosome biogenesis genetic 1 1 1 Negative Genetic
PET309 YLR067C Specific translational activator for the COX1 mRNA genetic 1 1 1 Negative Genetic
EFB1 YAL003W Translation elongation factor 1 beta genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TAD2 YJL035C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Negative Genetic
YCR016W YCR016W Putative protein of unknown function genetic 1 1 1 Negative Genetic
MSL5 YLR116W Component of commitment complex genetic 1 1 1 Negative Genetic
PUS5 YLR165C Pseudouridine synthase genetic 1 1 1 Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Negative Genetic
POP8 YBL018C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Positive Genetic
THR1 YHR025W Homoserine kinase genetic 1 1 1 Positive Genetic
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Positive Genetic
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
SHR3 YDL212W Endoplasmic reticulum packaging chaperone genetic 1 1 1 Positive Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Positive Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase genetic 1 1 1 Positive Genetic
ILV3 YJR016C Dihydroxyacid dehydratase genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Positive Genetic
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
PEA2 YER149C Coiled-coil 12S polarisome subunit genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Positive Genetic
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Negative Genetic
PRM6 YML047C Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
MIX17 YMR002W Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
CSR2 YPR030W Nuclear ubiquitin protein ligase binding protein genetic 1 1 1 Negative Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Synthetic Growth Defect
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Dosage Lethality
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Negative Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
CRG1 YHR209W S-AdoMet-dependent methyltransferase involved in lipid homeostasis genetic 1 1 1 Synthetic Growth Defect
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Synthetic Growth Defect
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Positive Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Positive Genetic
NUS1 YDL193W Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 genetic 1 1 1 Positive Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 1 1 1 Positive Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Positive Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Positive Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Positive Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Positive Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Positive Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Positive Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Positive Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Positive Genetic
ERG27 YLR100W 3-keto sterol reductase genetic 1 1 1 Positive Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Positive Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Positive Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Positive Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Positive Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Positive Genetic
UPS2 YLR168C Mitochondrial intermembrane space protein genetic 1 1 1 Positive Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Positive Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Positive Genetic
HSP32 YPL280W Possible chaperone and cysteine protease genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
PBN1 YCL052C Component of glycosylphosphatidylinositol-mannosyltransferase I genetic 1 1 1 Negative Genetic
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 1 1 1 Negative Genetic
SCM3 YDL139C Nonhistone component of centromeric chromatin genetic 1 1 1 Negative Genetic
ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing genetic 1 1 1 Negative Genetic
GUK1 YDR454C Guanylate kinase genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Negative Genetic
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Negative Genetic
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
TFG1 YGR186W TFIIF (Transcription Factor II) largest subunit genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Negative Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Negative Genetic
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing genetic 1 1 1 Negative Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Negative Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
TAF7 YMR227C TFIID subunit (67 kDa) genetic 1 1 1 Negative Genetic
RRN9 YMR270C Protein involved in promoting high level transcription of rDNA genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
RRP15 YPR143W Nucleolar protein genetic 1 1 1 Negative Genetic
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 1 1 1 Negative Genetic
RPB5 YBR154C RNA polymerase subunit ABC27 genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
RBA50 YDR527W Protein involved in transcription genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
MES1 YGR264C Methionyl-tRNA synthetase genetic 1 1 1 Negative Genetic
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
GSP1 YLR293C Ran GTPase genetic 1 1 1 Negative Genetic
TAF11 YML015C TFIID subunit (40 kDa) genetic 1 1 1 Negative Genetic
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 1 1 1 Negative Genetic
TAF4 YMR005W TFIID subunit (48 kDa) genetic 1 1 1 Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Negative Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
MGE1 YOR232W Mitochondrial matrix cochaperone genetic 1 1 1 Negative Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 1 1 1 Negative Genetic
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 1 1 1 Negative Genetic
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Negative Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
SPO7 YAL009W Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
TVS1 YCR061W Protein of unknown function genetic 1 1 1 Negative Genetic
PRM7 YDL039C Pheromone-regulated protein genetic 1 1 1 Negative Genetic
YDL086W YDL086W Putative carboxymethylenebutenolidase genetic 1 1 1 Negative Genetic
RGT2 YDL138W Plasma membrane high glucose sensor that regulates glucose transport genetic 1 1 1 Negative Genetic
ENT1 YDL161W Epsin-like protein involved in endocytosis and actin patch assembly genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
EKI1 YDR147W Ethanolamine kinase genetic 1 1 1 Negative Genetic
REF2 YDR195W RNA-binding protein genetic 1 1 1 Negative Genetic
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone genetic 1 1 1 Negative Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 1 1 1 Negative Genetic
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p genetic 1 1 1 Negative Genetic
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Negative Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Negative Genetic
MXR1 YER042W Methionine-S-sulfoxide reductase genetic 1 1 1 Negative Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Negative Genetic
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 1 1 1 Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
RMD9 YGL107C Mitochondrial protein that controls mitochondrial gene expression genetic 1 1 1 Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
YGL188C-A YGL188C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR035C YGR035C Putative protein of unknown function, potential Cdc28p substrate genetic 1 1 1 Negative Genetic
YGR111W YGR111W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Negative Genetic
COQ6 YGR255C Flavin-dependent monooxygenase involved in ubiquinone biosynthesis genetic 1 1 1 Negative Genetic
OSH7 YHR001W Oxysterol-binding phosphatidylserine transferase genetic 1 1 1 Negative Genetic
SPO22 YIL073C Meiosis-specific protein essential for chromosome synapsis genetic 1 1 1 Negative Genetic
YIL152W YIL152W Putative protein of unknown function genetic 1 1 1 Negative Genetic
COA3 YJL062W-A Mitochondrial protein required for cytochrome c oxidase assembly genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
HMS2 YJR147W Protein with similarity to heat shock transcription factors genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
PRY2 YKR013W Sterol binding protein involved in the export of acetylated sterols genetic 1 1 1 Negative Genetic
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Negative Genetic
LMO1 YLL007C Homolog of mammalian ELMO (Engulfment and celL MOtility) genetic 1 1 1 Negative Genetic
TFS1 YLR178C Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p) genetic 1 1 1 Negative Genetic
UCC1 YLR224W F-box protein and component of SCF ubiquitin ligase complexes genetic 1 1 1 Negative Genetic
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
YLR297W YLR297W Protein of unknown function genetic 1 1 1 Negative Genetic
RPS1A YLR441C Ribosomal protein of the small (40S) subunit genetic 1 1 1 Negative Genetic
YML053C YML053C Putative protein of unknown function genetic 1 1 1 Negative Genetic
PSO2 YMR137C Nuclease required for DNA single- and double-strand break repair genetic 1 1 1 Negative Genetic
YMR155W YMR155W Putative protein of unknown function genetic 1 1 1 Negative Genetic
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Negative Genetic
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
LRO1 YNR008W Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) genetic 1 1 1 Negative Genetic
RRT2 YBR246W Methylesterase performing penultimate step of diphthamide biosynthesis genetic 1 1 1 Negative Genetic
NRG1 YDR043C Transcriptional repressor genetic 1 1 1 Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Negative Genetic
YDR248C YDR248C Putative gluconokinase genetic 1 1 1 Negative Genetic
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 genetic 1 1 1 Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Negative Genetic
YIL054W YIL054W Protein of unknown function genetic 1 1 1 Negative Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Negative Genetic
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Negative Genetic
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
SUV3 YPL029W ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
UBP12 YJL197W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Negative Genetic
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Negative Genetic
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Positive Genetic
FIN1 YDR130C Spindle pole body-related intermediate filament protein genetic 1 1 1 Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Positive Genetic
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Positive Genetic
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 1 1 1 Positive Genetic
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs genetic 1 1 1 Negative Genetic
ENT3 YJR125C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
BCP1 YDR361C Essential nuclear chaperone for ribosomal protein Rpl23p genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Negative Genetic
ABD1 YBR236C Methyltransferase genetic 1 1 1 Negative Genetic
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Positive Genetic
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 1 1 1 Dosage Rescue
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Positive Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
BDF1 YLR399C BET family transcriptional regulator physical 1 1 1 Affinity Capture-MS
AIM21 YIR003W Subunit of a complex that associates with actin filaments genetic 1 1 1 Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 1 1 1 Affinity Capture-MS
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
CIA2 YHR122W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
BLM10 YFL007W Proteasome activator genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Positive Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Negative Genetic
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Positive Genetic
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 1 1 1 Negative Genetic
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Synthetic Growth Defect
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity physical 1 1 1 Reconstituted Complex
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 1 1 1 Synthetic Growth Defect
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Negative Genetic
ATP18 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Positive Genetic
ATG21 YPL100W Phosphoinositide binding protein genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
ASI2 YNL159C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
ALG2 YGL065C Mannosyltransferase in the N-linked glycosylation pathway genetic 1 1 1 Negative Genetic
ATG41 YPL250C Protein of unknown function genetic 1 1 1 Negative Genetic
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3 genetic 1 1 1 Negative Genetic