Standard name Systematic name Name description Description
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
Visualize the interactome of COS7
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 153

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.892 0.866 0.848
Vac/Vac Memb 0.083 0.113 0.106
Mito NaN NaN 0.077

GFP localization & abundance

GFP localization GFP abundance
ambiguous no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
COS7 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 2 1 Positive Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family regulation 1 1 1 RNA-sequencing evidence
SIR3 YLR442C Silencing protein regulation 1 1 1 RNA-sequencing evidence
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains regulation 1 1 1 RNA-sequencing evidence
CEF1 YMR213W Essential splicing factor genetic 1 1 1 Negative Genetic
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
AAR2 YBL074C Component of the U5 snRNP complex genetic 1 1 1 Negative Genetic
BCP1 YDR361C Essential nuclear chaperone for ribosomal protein Rpl23p genetic 1 1 1 Positive Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
CAP1 YKL007W Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Positive Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Positive Genetic
BLM10 YFL007W Proteasome activator genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton genetic 1 1 1 Positive Genetic
ATG12 YBR217W Ubiquitin-like modifier involved in autophagy and the Cvt pathway genetic 1 1 1 Positive Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
AFR1 YDR085C Protein required for pheromone-induced projection (shmoo) formation genetic 1 1 1 Negative Genetic
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Negative Genetic
CBR1 YIL043C Cytochrome b reductase and NADH-dependent reductase for Dph3p genetic 1 1 1 Negative Genetic
ATG5 YPL149W Conserved protein involved in autophagy and the Cvt pathway genetic 1 1 1 Positive Genetic
ATG16 YMR159C Conserved protein involved in autophagy genetic 1 1 1 Positive Genetic
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
ATG8 YBL078C Ub-like protein genetic 1 1 1 Positive Genetic
CBF2 YGR140W Essential kinetochore protein genetic 1 1 1 Negative Genetic
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 1 1 1 Negative Genetic
ARO80 YDR421W Zinc finger transcriptional activator of the Zn2Cys6 family genetic 1 1 1 Negative Genetic
ATP18 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 1 1 1 Positive Genetic
AIM22 YJL046W Lipoate-protein ligase genetic 1 1 1 Positive Genetic
ADE16 YLR028C Enzyme of 'de novo' purine biosynthesis genetic 1 1 1 Positive Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Negative Genetic
CCW22 YDR134C Cell wall protein genetic 1 1 1 Negative Genetic
AIM11 YER093C-A Protein of unknown function genetic 1 1 1 Positive Genetic
CHS7 YHR142W Protein of unknown function genetic 1 1 1 Positive Genetic
CIS3 YJL158C Mannose-containing glycoprotein constituent of the cell wall genetic 1 1 1 Negative Genetic
PEX29 YDR479C ER-resident protein involved in peroxisomal biogenesis physical 1 1 1 PCA
VTC2 YFL004W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex physical 1 1 1 PCA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 1 1 1 Negative Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Positive Genetic
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Positive Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Positive Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Positive Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Positive Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Positive Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Positive Genetic
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Positive Genetic
MES1 YGR264C Methionyl-tRNA synthetase genetic 1 1 1 Positive Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Positive Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Positive Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
SPC3 YLR066W Subunit of signal peptidase complex genetic 1 1 1 Positive Genetic
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Positive Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Positive Genetic
MCM1 YMR043W Transcription factor genetic 1 1 1 Positive Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Positive Genetic
RIB2 YOL066C Bifunctional DRAP deaminase tRNA:pseudouridine synthase genetic 1 1 1 Positive Genetic
MGE1 YOR232W Mitochondrial matrix cochaperone genetic 1 1 1 Positive Genetic
TIM50 YPL063W Essential component of the TIM23 complex genetic 1 1 1 Positive Genetic
SHG1 YBR258C Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Positive Genetic
PER1 YCR044C Protein of the endoplasmic reticulum genetic 1 1 1 Positive Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Positive Genetic
SDH4 YDR178W Membrane anchor subunit of succinate dehydrogenase (SDH) genetic 1 1 1 Positive Genetic
ECM32 YER176W DNA dependent ATPase/DNA helicase genetic 1 1 1 Positive Genetic
RME1 YGR044C Zinc finger protein involved in control of meiosis genetic 1 1 1 Positive Genetic
SCW4 YGR279C Cell wall protein with similarity to glucanases genetic 1 1 1 Positive Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Positive Genetic
SOD2 YHR008C Mitochondrial manganese superoxide dismutase genetic 1 1 1 Positive Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Positive Genetic
MCR1 YKL150W Mitochondrial NADH-cytochrome b5 reductase genetic 1 1 1 Positive Genetic
YKR041W YKR041W Protein of unknown function genetic 1 1 1 Positive Genetic
UTH1 YKR042W Mitochondrial inner membrane protein genetic 1 1 1 Positive Genetic
SPA2 YLL021W Component of the polarisome genetic 1 1 1 Positive Genetic
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription genetic 1 1 1 Positive Genetic
SDH2 YLL041C Iron-sulfur protein subunit of succinate dehydrogenase genetic 1 1 1 Positive Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Positive Genetic
PEX13 YLR191W Peroxisomal importomer complex component genetic 1 1 1 Positive Genetic
DUS3 YLR401C Dihydrouridine synthase genetic 1 1 1 Positive Genetic
TDA5 YLR426W Putative protein of unknown function genetic 1 1 1 Positive Genetic
RPL6B YLR448W Ribosomal 60S subunit protein L6B genetic 1 1 1 Positive Genetic
PAI3 YMR174C Cytoplasmic proteinase A (Pep4p) inhibitor genetic 1 1 1 Positive Genetic
YMR206W YMR206W Putative protein of unknown function genetic 1 1 1 Positive Genetic
TRI1 YMR233W Non-essential sumoylated protein of unknown function genetic 1 1 1 Positive Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
YNL011C YNL011C Putative protein of unknown function genetic 1 1 1 Positive Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Positive Genetic
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 1 1 1 Positive Genetic
CYC2 YOR037W Mitochondrial peripheral inner membrane protein genetic 1 1 1 Positive Genetic
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p genetic 1 1 1 Positive Genetic
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Positive Genetic
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Positive Genetic
MRS2 YOR334W Mitochondrial inner membrane Mg(2+) channel genetic 1 1 1 Positive Genetic
RLM1 YPL089C MADS-box transcription factor genetic 1 1 1 Positive Genetic
ISU1 YPL135W Conserved protein of the mitochondrial matrix genetic 1 1 1 Positive Genetic
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 1 1 1 Positive Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Positive Genetic
MAK3 YPR051W Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) genetic 1 1 1 Positive Genetic
JID1 YPR061C Probable Hsp40p co-chaperone genetic 1 1 1 Positive Genetic
UBA3 YPR066W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Positive Genetic
LSM2 YBL026W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Negative Genetic
TPI1 YDR050C Triose phosphate isomerase, abundant glycolytic enzyme genetic 1 1 1 Negative Genetic
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Negative Genetic
SEC5 YDR166C Essential 107kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Negative Genetic
SLD5 YDR489W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 1 1 1 Negative Genetic
TYS1 YGR185C Cytoplasmic tyrosyl-tRNA synthetase genetic 1 1 1 Negative Genetic
SDA1 YGR245C Protein required for actin organization and passage through Start genetic 1 1 1 Negative Genetic
RRP3 YHR065C Protein involved in rRNA processing genetic 1 1 1 Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 1 1 1 Negative Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
PRE3 YJL001W Beta 1 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
PRP21 YJL203W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
NNF1 YJR112W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Negative Genetic
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
RPB8 YOR224C RNA polymerase subunit ABC14.5 genetic 1 1 1 Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 1 1 1 Negative Genetic
TFC8 YPL007C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 1 1 1 Negative Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Negative Genetic
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
PRP4 YPR178W Splicing factor genetic 1 1 1 Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Negative Genetic
NTG1 YAL015C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 1 1 1 Negative Genetic
SEO1 YAL067C Putative permease genetic 1 1 1 Negative Genetic
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
GAL10 YBR019C UDP-glucose-4-epimerase genetic 1 1 1 Negative Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
FIG1 YBR040W Integral membrane protein required for efficient mating genetic 1 1 1 Negative Genetic
IML3 YBR107C Outer kinetochore protein and component of the Ctf19 complex genetic 1 1 1 Negative Genetic
NGR1 YBR212W RNA binding protein that negatively regulates growth rate genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
EFM2 YBR271W S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Negative Genetic
CTP1 YBR291C Mitochondrial inner membrane citrate transporter genetic 1 1 1 Negative Genetic
YCL001W-A YCL001W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RNQ1 YCL028W [PIN(+)] prion genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
SPS22 YCL048W Protein of unknown function genetic 1 1 1 Negative Genetic
TAH1 YCR060W Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Negative Genetic
PST1 YDR055W Cell wall protein that contains a putative GPI-attachment site genetic 1 1 1 Negative Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
FMP16 YDR070C Protein of unknown function genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
GRX3 YDR098C Glutathione-dependent oxidoreductase genetic 1 1 1 Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Negative Genetic
YCF1 YDR135C Vacuolar glutathione S-conjugate transporter genetic 1 1 1 Negative Genetic
SAN1 YDR143C Ubiquitin-protein ligase genetic 1 1 1 Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Negative Genetic
ENT5 YDR153C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Negative Genetic
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity genetic 1 1 1 Negative Genetic
CSN9 YDR179C Subunit of the Cop9 signalosome genetic 1 1 1 Negative Genetic
SND1 YDR186C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
NUP42 YDR192C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
SIP1 YDR422C One of three alternate beta-subunits of the Snf1p kinase complex genetic 1 1 1 Negative Genetic
SPO73 YER046W Meiosis-specific protein required for prospore membrane morphogenesis genetic 1 1 1 Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Negative Genetic
DSE1 YER124C Daughter cell-specific protein genetic 1 1 1 Negative Genetic
RTR1 YER139C Dual specificity protein phosphatase genetic 1 1 1 Negative Genetic
YER187W YER187W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RGD2 YFL047W GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p genetic 1 1 1 Negative Genetic
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein genetic 1 1 1 Negative Genetic
SAE2 YGL175C Endonuclease required for telomere elongation genetic 1 1 1 Negative Genetic
DSD1 YGL196W D-serine dehydratase (aka D-serine ammonia-lyase) genetic 1 1 1 Negative Genetic
MDS3 YGL197W Putative component of the TOR regulatory pathway genetic 1 1 1 Negative Genetic
YIP4 YGL198W Protein that interacts with Rab GTPases genetic 1 1 1 Negative Genetic
TAN1 YGL232W Putative tRNA acetyltransferase genetic 1 1 1 Negative Genetic
MTO1 YGL236C Mitochondrial protein genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
VEL1 YGL258W Protein of unknown function genetic 1 1 1 Negative Genetic
DPC29 YGR021W Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 genetic 1 1 1 Negative Genetic
PDX1 YGR193C E3-binding protein of the mitochondrial pyruvate dehydrogenase complex genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Negative Genetic
MVB12 YGR206W ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers genetic 1 1 1 Negative Genetic
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Negative Genetic
YAP1802 YGR241C Protein of the AP180 family, involved in clathrin cage assembly genetic 1 1 1 Negative Genetic
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease genetic 1 1 1 Negative Genetic
HUA1 YGR268C Cytoplasmic protein containing a zinc finger domain genetic 1 1 1 Negative Genetic
YGR273C YGR273C Putative protein of unknown function genetic 1 1 1 Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Negative Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YHI9 YHR029C Protein of unknown function genetic 1 1 1 Negative Genetic
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase genetic 1 1 1 Negative Genetic
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family genetic 1 1 1 Negative Genetic
PIG2 YIL045W Putative type-1 protein phosphatase targeting subunit genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
FLX1 YIL134W Mitochondrial flavin adenine dinucleotide transporter genetic 1 1 1 Negative Genetic
OM45 YIL136W Mitochondrial outer membrane protein of unknown function genetic 1 1 1 Negative Genetic
SUC2 YIL162W Invertase genetic 1 1 1 Negative Genetic
NIT1 YIL164C Nitrilase genetic 1 1 1 Negative Genetic
VTH1 YIL173W Putative membrane glycoprotein genetic 1 1 1 Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
YJL027C YJL027C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane genetic 1 1 1 Negative Genetic
MET3 YJR010W ATP sulfurylase genetic 1 1 1 Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
LAC1 YKL008C Ceramide synthase component genetic 1 1 1 Negative Genetic
PHD1 YKL043W Transcriptional activator that enhances pseudohyphal growth genetic 1 1 1 Negative Genetic
MMO1 YKL044W Protein of unknown function genetic 1 1 1 Negative Genetic
MNR2 YKL064W Vacuolar membrane protein required for magnesium homeostasis genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Negative Genetic
MRP49 YKL167C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
YRA2 YKL214C Member of the REF (RNA and export factor binding proteins) family genetic 1 1 1 Negative Genetic
FMP46 YKR049C Putative redox protein containing a thioredoxin fold genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
PML1 YLR016C Subunit of the RES complex genetic 1 1 1 Negative Genetic
YLR046C YLR046C Putative membrane protein genetic 1 1 1 Negative Genetic
RFU1 YLR073C Protein that inhibits Doa4p deubiquitinating activity genetic 1 1 1 Negative Genetic
RKM5 YLR137W Protein lysine methyltransferase genetic 1 1 1 Negative Genetic
DPH6 YLR143W Diphthamide synthetase genetic 1 1 1 Negative Genetic
IDP2 YLR174W Cytosolic NADP-specific isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
VTA1 YLR181C Multivesicular body (MVB) protein genetic 1 1 1 Negative Genetic
NCW2 YLR194C GPI-anchored protein involved in cell wall remodeling genetic 1 1 1 Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
RED1 YLR263W Protein component of the synaptonemal complex axial elements genetic 1 1 1 Negative Genetic
YLR278C YLR278C Zinc-cluster protein genetic 1 1 1 Negative Genetic
NNT1 YLR285W S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Negative Genetic
UBC12 YLR306W Enzyme that mediates the conjugation of Rub1p genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
REC102 YLR329W Protein involved in early stages of meiotic recombination genetic 1 1 1 Negative Genetic
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Negative Genetic
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Negative Genetic
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs genetic 1 1 1 Negative Genetic
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 1 1 1 Negative Genetic
FAR3 YMR052W Protein of unknown function genetic 1 1 1 Negative Genetic
YMR085W YMR085W Putative protein of unknown function genetic 1 1 1 Negative Genetic
NDE1 YMR145C Mitochondrial external NADH dehydrogenase genetic 1 1 1 Negative Genetic
TPP1 YMR156C DNA 3'-phosphatase genetic 1 1 1 Negative Genetic
ZRC1 YMR243C Vacuolar membrane zinc transporter genetic 1 1 1 Negative Genetic
COX7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
YMR316C-A YMR316C-A Protein of unknown function genetic 1 1 1 Negative Genetic
HRB1 YNL004W Poly(A+) RNA-binding protein genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
OCA1 YNL099C Putative protein tyrosine phosphatase genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PET494 YNR045W Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
MAN2 YNR073C Mannitol dehydrogenase genetic 1 1 1 Negative Genetic
IRC10 YOL015W Protein of unknown function genetic 1 1 1 Negative Genetic
PSK2 YOL045W PAS-domain containing serine/threonine protein kinase genetic 1 1 1 Negative Genetic
PFK27 YOL136C 6-phosphofructo-2-kinase genetic 1 1 1 Negative Genetic
CRS5 YOR031W Copper-binding metallothionein genetic 1 1 1 Negative Genetic
HMS1 YOR032C bHLH protein with similarity to myc-family transcription factors genetic 1 1 1 Negative Genetic
CUE5 YOR042W Ubiquitin-binding protein genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
RUP1 YOR138C Protein that regulates ubiquitination of Rsp5p genetic 1 1 1 Negative Genetic
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 1 1 1 Negative Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 1 1 1 Negative Genetic
MOD5 YOR274W Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase genetic 1 1 1 Negative Genetic
COT1 YOR316C Vacuolar transporter that mediates zinc transport into the vacuole genetic 1 1 1 Negative Genetic
ULA1 YPL003W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Negative Genetic
RQC2 YPL009C Component of the Ribosome Quality Control (RQC) complex genetic 1 1 1 Negative Genetic
EEB1 YPL095C Acyl-coenzymeA:ethanol O-acyltransferase genetic 1 1 1 Negative Genetic
RNY1 YPL123C Vacuolar RNase of the T(2) family genetic 1 1 1 Negative Genetic
RDS2 YPL133C Transcription factor involved in regulating gluconeogenesis genetic 1 1 1 Negative Genetic
OYE3 YPL171C Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) genetic 1 1 1 Negative Genetic
FLC1 YPL221W Flavin adenine dinucleotide transporter genetic 1 1 1 Negative Genetic
FMP40 YPL222W Mitochondrial AMPylator in the pseudokinase selenoprotein-O family genetic 1 1 1 Negative Genetic
GYP5 YPL249C GTPase-activating protein (GAP) for yeast Rab family members genetic 1 1 1 Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
SPE3 YPR069C Spermidine synthase genetic 1 1 1 Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
YPR096C YPR096C Protein of unknown function genetic 1 1 1 Negative Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Positive Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 1 1 1 Negative Genetic
ATG41 YPL250C Protein of unknown function genetic 1 1 1 Positive Genetic
CMC1 YKL137W Copper-binding protein of the mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Positive Genetic
ALD3 YMR169C Cytoplasmic aldehyde dehydrogenase genetic 1 1 1 Negative Genetic