Standard name Systematic name Name description Description
KSP1 YHR082C Serine/threonine protein kinase Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress
Visualize the interactome of KSP1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.968 0.974 0.972

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 1270

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
KSP1 4 0 0 2 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
KOG1 YHR186C Subunit of TORC1 physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 2 2 2 PCA, Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 2 2 2 Dosage Growth Defect, Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 2 2 2 Two-hybrid, Affinity Capture-MS
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p physical 2 2 2 Biochemical Activity, Reconstituted Complex
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 2 2 2 Protein-RNA, Affinity Capture-RNA
ATG1 YGL180W Protein serine/threonine kinase genetic 2 2 2 Negative Genetic, Phenotypic Suppression
CDC73 YLR418C Component of the Paf1p complex genetic 2 1 2 Negative Genetic, Negative Genetic
ABD1 YBR236C Methyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 2 1 2 Negative Genetic, Negative Genetic
GCN3 YKR026C Alpha subunit of translation initiation factor eIF2B genetic 2 1 2 Negative Genetic, Negative Genetic
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 2 1 2 Negative Genetic, Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Positive Genetic, Positive Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 2 1 2 Negative Genetic, Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 2 1 2 Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 2 1 2 Negative Genetic, Negative Genetic
DMA1 YHR115C Ubiquitin-protein ligase (E3) genetic 2 1 2 Negative Genetic, Negative Genetic
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSD1 YDR293C Translational repressor genetic 2 1 2 Negative Genetic, Negative Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 2 1 2 Positive Genetic, Positive Genetic
RAS2 YNL098C GTP-binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 2 1 2 Negative Genetic, Negative Genetic
PNT1 YOR266W Mitochondrial integral inner membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
STM1 YLR150W Protein required for optimal translation under nutrient stress genetic 2 1 2 Negative Genetic, Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 2 1 2 Negative Genetic, Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 1 2 Negative Genetic, Negative Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 2 1 2 Negative Genetic, Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 2 1 2 Negative Genetic, Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
MBR1 YKL093W Protein involved in mitochondrial functions and stress response genetic 2 1 2 Negative Genetic, Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 2 1 2 Negative Genetic, Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 2 1 2 Negative Genetic, Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 2 1 2 Negative Genetic, Negative Genetic
PAA1 YDR071C Polyamine acetyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 2 1 2 Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 2 Negative Genetic, Negative Genetic
MGP12 YDR286C Mitochondrial protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
MSC2 YDR205W Endoplasmic reticulum zinc transporter genetic 2 1 2 Negative Genetic, Negative Genetic
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p genetic 2 1 2 Negative Genetic, Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 2 1 2 Negative Genetic, Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 2 1 2 Negative Genetic, Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 2 1 2 Negative Genetic, Negative Genetic
YCL042W YCL042W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 2 1 2 Negative Genetic, Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 2 1 2 Positive Genetic, Positive Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 2 1 2 Negative Genetic, Negative Genetic
ATG8 YBL078C Ub-like protein genetic 2 1 2 Negative Genetic, Negative Genetic
HAP4 YKL109W Transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 2 1 2 Positive Genetic, Positive Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 2 1 2 Negative Genetic, Negative Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 2 1 2 Negative Genetic, Negative Genetic
TIF4632 YGL049C Translation initiation factor eIF4G and scaffold protein regulation 2 2 1 protein kinase assay evidence, qualitative western immunoblotting evidence
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein regulation 2 2 1 protein kinase assay evidence, qualitative western immunoblotting evidence
TOR1 YJR066W PIK-related protein kinase and rapamycin target physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
CTT1 YGR088W Cytosolic catalase T genetic 2 2 1 Phenotypic Suppression, Dosage Rescue
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 2 1 1 Dosage Lethality, Dosage Lethality
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
HOS1 YPR068C Class I histone deacetylase (HDAC) family member genetic 2 1 1 Dosage Lethality, Dosage Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SNF1 YDR477W AMP-activated S/T protein kinase regulation 1 1 1 qualitative western immunoblotting evidence
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 1 1 1 Biochemical Activity
HAS1 YMR290C ATP-dependent RNA helicase physical 1 1 1 Biochemical Activity
FRT2 YAL028W Tail-anchored ER membrane protein of unknown function physical 1 1 1 Biochemical Activity
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 Biochemical Activity
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 Biochemical Activity
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase physical 1 1 1 Biochemical Activity
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 1 1 1 Biochemical Activity
ARO1 YDR127W Pentafunctional arom protein physical 1 1 1 Affinity Capture-MS
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
BEM1 YBR200W Protein containing SH3-domains physical 1 1 1 Biochemical Activity
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) physical 1 1 1 Affinity Capture-MS
IPI3 YNL182C Component of the Rix1 complex and pre-replicative complexes (pre-RCs) physical 1 1 1 Biochemical Activity
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Phenotypic Enhancement
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 1 1 1 Biochemical Activity
GCN2 YDR283C Protein kinase genetic 1 1 1 Negative Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 1 1 1 Biochemical Activity
BDF2 YDL070W Protein involved in transcription initiation physical 1 1 1 Biochemical Activity
HHF1 YBR009C Histone H4 physical 1 1 1 Biochemical Activity
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
FAP7 YDL166C Essential NTPase required for small ribosome subunit synthesis physical 1 1 1 Biochemical Activity
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling physical 1 1 1 Reconstituted Complex
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Positive Genetic
HER1 YOR227W Protein of unknown function genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Positive Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Biochemical Activity
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex physical 1 1 1 Biochemical Activity
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering physical 1 1 1 Biochemical Activity
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Biochemical Activity
CAM1 YPL048W One of two isoforms of the gamma subunit of eEF1B physical 1 1 1 Biochemical Activity
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles physical 1 1 1 Biochemical Activity
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis physical 1 1 1 Biochemical Activity
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-MS
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
DTD1 YDL219W D-Tyr-tRNA(Tyr) deacylase physical 1 1 1 Biochemical Activity
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails physical 1 1 1 Biochemical Activity
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes physical 1 1 1 Biochemical Activity
HEL2 YDR266C RING finger ubiquitin ligase (E3) physical 1 1 1 Biochemical Activity
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
CMP2 YML057W Calcineurin A physical 1 1 1 Affinity Capture-MS
GSP1 YLR293C Ran GTPase physical 1 1 1 Biochemical Activity
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Negative Genetic
DIG2 YDR480W MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Biochemical Activity
BUD13 YGL174W Subunit of the RES complex genetic 1 1 1 Negative Genetic
ADK1 YDR226W Adenylate kinase, required for purine metabolism physical 1 1 1 Biochemical Activity
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 1 1 1 Negative Genetic
KDX1 YKL161C Protein kinase physical 1 1 1 Affinity Capture-MS
KNS1 YLL019C Protein kinase involved in negative regulation of PolIII transcription genetic 1 1 1 Negative Genetic
BUD32 YGR262C Protein kinase genetic 1 1 1 Dosage Growth Defect
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase physical 1 1 1 Biochemical Activity
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV physical 1 1 1 Biochemical Activity
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 1 1 1 Negative Genetic
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase genetic 1 1 1 Positive Genetic
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
KIN2 YLR096W S/T protein kinase physical 1 1 1 Affinity Capture-MS
CHS1 YNL192W Chitin synthase I physical 1 1 1 Affinity Capture-MS
TPD3 YAL016W Regulatory subunit A of the heterotrimeric PP2A complex physical 1 1 1 Affinity Capture-MS
PRI2 YKL045W Subunit of DNA primase physical 1 1 1 Affinity Capture-MS
PSY2 YNL201C Subunit of protein phosphatase PP4 complex physical 1 1 1 Affinity Capture-MS
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 1 1 1 Two-hybrid
UBA1 YKL210W Ubiquitin activating enzyme (E1) physical 1 1 1 Affinity Capture-MS
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p physical 1 1 1 Affinity Capture-MS
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p physical 1 1 1 Biochemical Activity
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane physical 1 1 1 Biochemical Activity
VHR2 YER064C Non-essential nuclear protein physical 1 1 1 Biochemical Activity
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 Biochemical Activity
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Dosage Growth Defect
YMR295C YMR295C Protein of unknown function that associates with ribosomes physical 1 1 1 Biochemical Activity
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome physical 1 1 1 Biochemical Activity
YCR099C YCR099C Putative protein of unknown function physical 1 1 1 Biochemical Activity
VAS1 YGR094W Mitochondrial and cytoplasmic valyl-tRNA synthetase physical 1 1 1 Biochemical Activity
TSC10 YBR265W 3-ketosphinganine reductase physical 1 1 1 Biochemical Activity
YDR170W-A YDR170W-A Retrotransposon TYA Gag gene physical 1 1 1 Biochemical Activity
LEO1 YOR123C Component of the Paf1 complex physical 1 1 1 Biochemical Activity
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Negative Genetic
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p physical 1 1 1 Biochemical Activity
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Biochemical Activity
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase physical 1 1 1 Biochemical Activity
UBX7 YBR273C UBX (ubiquitin regulatory X) domain-containing protein physical 1 1 1 Biochemical Activity
NAT3 YPR131C Catalytic subunit of the NatB N-terminal acetyltransferase physical 1 1 1 Biochemical Activity
MRX11 YPL041C Protein that associates with mitochondrial ribosome physical 1 1 1 Biochemical Activity
PEX1 YKL197C AAA-peroxin physical 1 1 1 Biochemical Activity
MSB3 YNL293W Rab GTPase-activating protein physical 1 1 1 Biochemical Activity
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p physical 1 1 1 Biochemical Activity
YGR038C-A YGR038C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta physical 1 1 1 Biochemical Activity
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid physical 1 1 1 Biochemical Activity
MGM1 YOR211C Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p physical 1 1 1 Biochemical Activity
TIF11 YMR260C Translation initiation factor eIF1A physical 1 1 1 Biochemical Activity
SLM3 YDL033C tRNA-specific 2-thiouridylase physical 1 1 1 Biochemical Activity
YPL150W YPL150W Protein kinase of unknown cellular role physical 1 1 1 Biochemical Activity
YML083C YML083C Protein of unknown function physical 1 1 1 Biochemical Activity
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body physical 1 1 1 Biochemical Activity
OSH2 YDL019C Member of an oxysterol-binding protein family with seven members physical 1 1 1 Biochemical Activity
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase physical 1 1 1 Biochemical Activity
LAA2 YBL010C Clathrin adaptor (adaptin) accessory protein physical 1 1 1 Biochemical Activity
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) physical 1 1 1 Biochemical Activity
MAC1 YMR021C Copper-sensing transcription factor physical 1 1 1 Biochemical Activity
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth physical 1 1 1 Biochemical Activity
SOL2 YCR073W-A Protein with a possible role in tRNA export physical 1 1 1 Biochemical Activity
YKR070W YKR070W Putative protein of unknown function physical 1 1 1 Biochemical Activity
MRX9 YDL027C Protein that associates with mitochondrial ribosome physical 1 1 1 Biochemical Activity
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 1 1 1 Biochemical Activity
SLY41 YOR307C Protein involved in ER-to-Golgi transport physical 1 1 1 Biochemical Activity
LAF1 YMR102C Sterol-binding beta-propeller protein physical 1 1 1 Biochemical Activity
TRM8 YDL201W Catalytic subunit of a tRNA methyltransferase complex physical 1 1 1 Biochemical Activity
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex physical 1 1 1 Biochemical Activity
SOF1 YLL011W Protein required for biogenesis of 40S (small) ribosomal subunit physical 1 1 1 Biochemical Activity
SEC62 YPL094C Essential subunit of Sec63 complex physical 1 1 1 Biochemical Activity
YBR138C YBR138C Cytoplasmic protein of unknown function physical 1 1 1 Biochemical Activity
YPR158W-A YPR158W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YDJ1 YNL064C Type I HSP40 co-chaperone physical 1 1 1 Biochemical Activity
MST27 YGL051W Putative integral membrane protein, involved in vesicle formation physical 1 1 1 Biochemical Activity
YRR1 YOR162C Zn2-Cys6 zinc-finger transcription factor physical 1 1 1 Biochemical Activity
YBR225W YBR225W Putative protein of unknown function physical 1 1 1 Biochemical Activity
SRO7 YPR032W Effector of Rab GTPase Sec4p physical 1 1 1 Biochemical Activity
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Biochemical Activity
PPN2 YNL217W Zn2+-dependent endopolyphosphatase physical 1 1 1 Biochemical Activity
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex physical 1 1 1 Biochemical Activity
PAR32 YDL173W Low complexity protein physical 1 1 1 Biochemical Activity
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Biochemical Activity
RIM4 YHL024W Putative RNA-binding protein physical 1 1 1 Biochemical Activity
PBP2 YBR233W RNA binding protein physical 1 1 1 Biochemical Activity
YDR034C-C YDR034C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
NGL2 YMR285C Protein involved in 5.8S rRNA processing physical 1 1 1 Biochemical Activity
YGR027W-A YGR027W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
UGA4 YDL210W GABA (gamma-aminobutyrate) permease physical 1 1 1 Biochemical Activity
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Biochemical Activity
NVJ2 YPR091C Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) physical 1 1 1 Biochemical Activity
YOL103W-A YOL103W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
RCM1 YNL022C rRNA m5C methyltransferase physical 1 1 1 Biochemical Activity
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay physical 1 1 1 Biochemical Activity
PDI1 YCL043C Protein disulfide isomerase physical 1 1 1 Biochemical Activity
RPB5 YBR154C RNA polymerase subunit ABC27 physical 1 1 1 Biochemical Activity
PRX1 YBL064C Mitochondrial peroxiredoxin with thioredoxin peroxidase activity physical 1 1 1 Biochemical Activity
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery physical 1 1 1 Biochemical Activity
NGR1 YBR212W RNA binding protein that negatively regulates growth rate physical 1 1 1 Biochemical Activity
VHS2 YIL135C Regulator of septin dynamics physical 1 1 1 Biochemical Activity
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting physical 1 1 1 Biochemical Activity
MRPS28 YDR337W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Biochemical Activity
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Biochemical Activity
RMD8 YFR048W Cytosolic protein required for sporulation physical 1 1 1 Biochemical Activity
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 1 1 1 Biochemical Activity
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Biochemical Activity
LYS21 YDL131W Homocitrate synthase isozyme physical 1 1 1 Biochemical Activity
UBP9 YER098W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 1 1 1 Biochemical Activity
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA physical 1 1 1 Biochemical Activity
YMR155W YMR155W Putative protein of unknown function physical 1 1 1 Biochemical Activity
UBX5 YDR330W UBX domain-containing protein that interacts with Cdc48p physical 1 1 1 Biochemical Activity
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Biochemical Activity
MSD1 YPL104W Mitochondrial aspartyl-tRNA synthetase physical 1 1 1 Biochemical Activity
YPR158C-C YPR158C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
TRM13 YOL125W 2'-O-methyltransferase physical 1 1 1 Biochemical Activity
MSK1 YNL073W Mitochondrial lysine-tRNA synthetase physical 1 1 1 Biochemical Activity
YML037C YML037C Putative protein of unknown function physical 1 1 1 Biochemical Activity
PTP2 YOR208W Phosphotyrosine-specific phosphatase physical 1 1 1 Biochemical Activity
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Biochemical Activity
RLI1 YDR091C Essential Fe-S protein physical 1 1 1 Biochemical Activity
SCJ1 YMR214W One of several homologs of bacterial chaperone DnaJ physical 1 1 1 Biochemical Activity
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Biochemical Activity
YPR137C-A YPR137C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
RSA3 YLR221C Protein with a likely role in ribosomal maturation physical 1 1 1 Biochemical Activity
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit physical 1 1 1 Biochemical Activity
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Positive Genetic
YME2 YMR302C Integral inner mitochondrial membrane protein physical 1 1 1 Biochemical Activity
YML045W-A YML045W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor physical 1 1 1 Biochemical Activity
YLR257W YLR257W Protein of unknown function physical 1 1 1 Biochemical Activity
NPL4 YBR170C Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase physical 1 1 1 Biochemical Activity
YNL054W-A YNL054W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YPL257W-A YPL257W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
LSM7 YNL147W Lsm (Like Sm) protein physical 1 1 1 Biochemical Activity
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain physical 1 1 1 Biochemical Activity
TYW1 YPL207W Iron-sulfur protein required for synthesis of wybutosine modified tRNA physical 1 1 1 Biochemical Activity
RPB8 YOR224C RNA polymerase subunit ABC14.5 physical 1 1 1 Biochemical Activity
THS1 YIL078W Threonyl-tRNA synthetase physical 1 1 1 Biochemical Activity
RNH70 YGR276C 3'-5' exoribonuclease physical 1 1 1 Biochemical Activity
SFK1 YKL051W Protein that regulates phospholipid asymmetry at plasma membrane physical 1 1 1 Biochemical Activity
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Biochemical Activity
LAS17 YOR181W Actin assembly factor physical 1 1 1 Biochemical Activity
LYS4 YDR234W Homoaconitase physical 1 1 1 Biochemical Activity
PBR1 YNL181W Putative oxidoreductase physical 1 1 1 Biochemical Activity
RGS2 YOR107W Negative regulator of glucose-induced cAMP signaling physical 1 1 1 Biochemical Activity
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex physical 1 1 1 Biochemical Activity
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
TDA1 YMR291W Protein kinase of unknown cellular role physical 1 1 1 Biochemical Activity
SGS1 YMR190C RecQ family nucleolar DNA helicase physical 1 1 1 Biochemical Activity
RKM4 YDR257C Ribosomal lysine methyltransferase physical 1 1 1 Biochemical Activity
PTH2 YBL057C One of two mitochondrially-localized peptidyl-tRNA hydrolases physical 1 1 1 Biochemical Activity
NDJ1 YOL104C Protein that regulates meiotic SPB cohesion and telomere clustering physical 1 1 1 Biochemical Activity
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
PKP2 YGL059W Mitochondrial protein kinase physical 1 1 1 Biochemical Activity
PKP2 YGL059W Mitochondrial protein kinase genetic 1 1 1 Negative Genetic
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Reconstituted Complex
LGE1 YPL055C Protein involved in histone H2B ubiquitination physical 1 1 1 Affinity Capture-MS
LST8 YNL006W Protein required for the transport of Gap1p physical 1 1 1 Affinity Capture-MS
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) physical 1 1 1 Affinity Capture-MS
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
YML6 YML025C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Affinity Capture-MS
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain physical 1 1 1 Reconstituted Complex
MFT1 YML062C Subunit of the THO complex physical 1 1 1 Reconstituted Complex
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase physical 1 1 1 Reconstituted Complex
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit physical 1 1 1 Reconstituted Complex
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Reconstituted Complex
YHR033W YHR033W Putative protein of unknown function physical 1 1 1 Reconstituted Complex
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Biochemical Activity
TIF4632 YGL049C Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Biochemical Activity
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Dosage Rescue
OPY1 YBR129C Protein of unknown function genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Positive Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking genetic 1 1 1 Positive Genetic
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 1 1 1 Negative Genetic
TFA2 YKR062W TFIIE small subunit genetic 1 1 1 Negative Genetic
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Positive Genetic
NPR1 YNL183C Protein kinase genetic 1 1 1 Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Phenotypic Suppression
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
SPC34 YKR037C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Dosage Growth Defect
YLR162W YLR162W Protein of unknown function genetic 1 1 1 Dosage Growth Defect
SHB17 YKR043C Sedoheptulose bisphosphatase involved in riboneogenesis genetic 1 1 1 Dosage Growth Defect
TIM13 YGR181W Mitochondrial intermembrane space protein genetic 1 1 1 Dosage Growth Defect
RPC40 YPR110C RNA polymerase subunit AC40 genetic 1 1 1 Dosage Growth Defect
WHI4 YDL224C Putative RNA binding protein genetic 1 1 1 Dosage Growth Defect
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Dosage Growth Defect
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Dosage Growth Defect
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Negative Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Negative Genetic
UBP2 YOR124C Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Negative Genetic
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs genetic 1 1 1 Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 1 1 1 Negative Genetic
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
NEJ1 YLR265C DNA end-binding protein required for nonhomologous end joining (NHEJ) genetic 1 1 1 Negative Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Positive Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Positive Genetic
SMT1 YJL147C Translational repressor of the mitochondrial ATP6/8 mRNA genetic 1 1 1 Positive Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Positive Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 1 1 1 Positive Genetic
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA genetic 1 1 1 Positive Genetic
STB1 YNL309W Protein with role in regulation of MBF-specific transcription at Start genetic 1 1 1 Positive Genetic
NCR1 YPL006W Vacuolar membrane protein involved with Npc2p in sterol trafficking genetic 1 1 1 Positive Genetic
SUV3 YPL029W ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
YPL039W YPL039W Putative protein of unknown function genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
YRB1 YDR002W Ran GTPase binding protein genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Negative Genetic
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Negative Genetic
MAL33 YBR297W MAL-activator protein genetic 1 1 1 Negative Genetic
RGT2 YDL138W Plasma membrane high glucose sensor that regulates glucose transport genetic 1 1 1 Negative Genetic
TRP1 YDR007W Phosphoribosylanthranilate isomerase genetic 1 1 1 Negative Genetic
RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
MXR1 YER042W Methionine-S-sulfoxide reductase genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Negative Genetic
QRI7 YDL104C Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Negative Genetic
YDL180W YDL180W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Negative Genetic
PET122 YER153C Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
PEX4 YGR133W Peroxisomal ubiquitin conjugating enzyme genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
XBP1 YIL101C Transcriptional repressor genetic 1 1 1 Negative Genetic
MHP1 YJL042W Microtubule-associated protein involved in microtubule organization genetic 1 1 1 Negative Genetic
RPE1 YJL121C D-ribulose-5-phosphate 3-epimerase genetic 1 1 1 Negative Genetic
TIF2 YJL138C Translation initiation factor eIF4A genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
YML096W YML096W Putative protein with similarity to asparagine synthetases genetic 1 1 1 Negative Genetic
YML108W YML108W Protein of unknown function genetic 1 1 1 Negative Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 1 1 1 Negative Genetic
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Negative Genetic
TFS1 YLR178C Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p) genetic 1 1 1 Negative Genetic
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Negative Genetic
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 1 1 1 Negative Genetic
YOR032W-A YOR032W-A Protein of unknown function genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Positive Genetic
SEC53 YFL045C Phosphomannomutase genetic 1 1 1 Negative Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
RPC17 YJL011C RNA polymerase III subunit C17 genetic 1 1 1 Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Negative Genetic
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
RPL43A YPR043W Ribosomal 60S subunit protein L43A genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 1 1 1 Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Negative Genetic
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Negative Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
RPO31 YOR116C RNA polymerase III largest subunit C160 genetic 1 1 1 Negative Genetic
NUT2 YPR168W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 1 1 1 Negative Genetic
ACS1 YAL054C Acetyl-coA synthetase isoform genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
ATG20 YDL113C Sorting nexin family member physical 1 1 1 Biochemical Activity
ATG4 YNL223W Conserved cysteine protease required for autophagy genetic 1 1 1 Negative Genetic
FPK1 YNR047W Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
CNM1 YBR063C Molecular tether on nuclear membrane genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
FMP48 YGR052W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role physical 1 1 1 Biochemical Activity
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Positive Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 1 1 1 Biochemical Activity
BIM1 YER016W Microtubule plus end-tracking protein physical 1 1 1 Affinity Capture-MS
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation physical 1 1 1 Biochemical Activity
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 1 1 1 Positive Genetic
CHA4 YLR098C DNA binding transcriptional activator physical 1 1 1 Biochemical Activity
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Positive Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Negative Genetic
BRF1 YGR246C TFIIIB B-related factor physical 1 1 1 Affinity Capture-MS
AMD1 YML035C AMP deaminase physical 1 1 1 Biochemical Activity
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Positive Genetic
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
ATG8 YBL078C Ub-like protein physical 1 1 1 Biochemical Activity
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
ATS1 YAL020C Protein required for modification of wobble nucleosides in tRNA physical 1 1 1 Biochemical Activity
BIK1 YCL029C Microtubule-associated protein physical 1 1 1 Affinity Capture-MS
BNR1 YIL159W Formin genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
GSY2 YLR258W Glycogen synthase physical 1 1 1 Reconstituted Complex
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) physical 1 1 1 Biochemical Activity
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Negative Genetic
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Negative Genetic
CYB2 YML054C Cytochrome b2 (L-lactate cytochrome-c oxidoreductase) physical 1 1 1 Biochemical Activity
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Negative Genetic
BCS1 YDR375C Protein translocase and chaperone required for Complex III assembly genetic 1 1 1 Negative Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) physical 1 1 1 Biochemical Activity
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation physical 1 1 1 Biochemical Activity
AQR1 YNL065W Plasma membrane transporter of the major facilitator superfamily physical 1 1 1 Biochemical Activity
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex physical 1 1 1 Biochemical Activity
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Negative Genetic
EUC1 YMR111C Sequence-specific DNA binding protein physical 1 1 1 Biochemical Activity
CCC1 YLR220W Vacuolar Fe2+/Mn2+ transporter physical 1 1 1 Biochemical Activity
ADE1 YAR015W N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase physical 1 1 1 Biochemical Activity
ATP16 YDL004W Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase physical 1 1 1 Biochemical Activity
IFA38 YBR159W Microsomal beta-keto-reductase physical 1 1 1 Biochemical Activity
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family physical 1 1 1 Affinity Capture-MS
GUK1 YDR454C Guanylate kinase genetic 1 1 1 Negative Genetic
IMP21 YIL154C Transcriptional activator involved in maintenance of ion homeostasis genetic 1 1 1 Dosage Growth Defect
ADH7 YCR105W NADPH-dependent medium chain alcohol dehydrogenase physical 1 1 1 Biochemical Activity
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Negative Genetic
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
CUZ1 YNL155W Protein with a role in the ubiquitin-proteasome pathway physical 1 1 1 Biochemical Activity
CUP9 YPL177C Homeodomain-containing transcriptional repressor physical 1 1 1 Biochemical Activity
APD1 YBR151W 2Fe-2S cytosolic protein of unknown function physical 1 1 1 Biochemical Activity
IRC19 YLL033W Protein of unknown function genetic 1 1 1 Positive Genetic
AVT3 YKL146W Vacuolar transporter physical 1 1 1 Biochemical Activity
CCW22 YDR134C Cell wall protein physical 1 1 1 Biochemical Activity
ADD37 YMR184W Protein of unknown function physical 1 1 1 Biochemical Activity
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
KIN82 YCR091W Putative serine/threonine protein kinase physical 1 1 1 Biochemical Activity
HUT1 YPL244C Protein with a role in UDP-galactose transport to the Golgi lumen physical 1 1 1 Biochemical Activity
CYC3 YAL039C Cytochrome c heme lyase (holocytochrome c synthase) physical 1 1 1 Biochemical Activity
AST1 YBL069W Lipid raft associated protein physical 1 1 1 Biochemical Activity
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly physical 1 1 1 Biochemical Activity
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Negative Genetic
ASI2 YNL159C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Dosage Growth Defect
ATG15 YCR068W Phospholipase genetic 1 1 1 Negative Genetic
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Negative Genetic
EMC3 YKL207W Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
AIM19 YIL087C Protein of unknown function genetic 1 1 1 Negative Genetic
HMS2 YJR147W Protein with similarity to heat shock transcription factors genetic 1 1 1 Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic