Standard name Systematic name Name description Description
KNS1 YLL019C Protein kinase involved in negative regulation of PolIII transcription Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation
Visualize the interactome of KNS1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
KNS1 3 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ATG3 YNR007C E2-like enzyme genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
PMP3 YDR276C Small plasma membrane protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 2 1 2 Negative Genetic, Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 2 1 2 Negative Genetic, Negative Genetic
RPS29A YLR388W Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 2 1 2 Positive Genetic, Positive Genetic
AIM21 YIR003W Subunit of a complex that associates with actin filaments genetic 2 1 1 Negative Genetic, Negative Genetic
FUM1 YPL262W Fumarase genetic 2 1 1 Negative Genetic, Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 2 1 1 Negative Genetic, Negative Genetic
MUB1 YMR100W MYND domain-containing protein genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SKN7 YHR206W Nuclear response regulator and transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
KNS1 YLL019C Protein kinase involved in negative regulation of PolIII transcription regulation 1 1 1 protein kinase assay evidence
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Biochemical Activity
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Synthetic Growth Defect
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Synthetic Growth Defect
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
CAP1 YKL007W Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 1 1 1 Synthetic Growth Defect
CDC11 YJR076C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Positive Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Negative Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Synthetic Growth Defect
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Synthetic Growth Defect
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
CAR2 YLR438W L-ornithine transaminase (OTAse) physical 1 1 1 Affinity Capture-MS
ACO1 YLR304C Aconitase genetic 1 1 1 Negative Genetic
BBC1 YJL020C Protein possibly involved in assembly of actin patches genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Positive Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
ARF1 YDL192W ADP-ribosylation factor genetic 1 1 1 Synthetic Growth Defect
GSP2 YOR185C GTP binding protein (mammalian Ranp homolog) genetic 1 1 1 Negative Genetic
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Synthetic Growth Defect
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p physical 1 1 1 Affinity Capture-MS
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex physical 1 1 1 Affinity Capture-MS
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase physical 1 1 1 Two-hybrid
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 1 1 1 Two-hybrid
LAF1 YMR102C Sterol-binding beta-propeller protein physical 1 1 1 Biochemical Activity
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes physical 1 1 1 Biochemical Activity
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 1 1 1 Affinity Capture-MS
MAK5 YBR142W Essential nucleolar protein physical 1 1 1 Affinity Capture-MS
MRM1 YOR201C Ribose methyltransferase physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase genetic 1 1 1 Negative Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing physical 1 1 1 Affinity Capture-MS
NOP4 YPL043W Nucleolar protein physical 1 1 1 Affinity Capture-MS
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome physical 1 1 1 Affinity Capture-MS
PET127 YOR017W Protein with a role in 5'-end processing of mitochondrial RNAs physical 1 1 1 Affinity Capture-MS
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling physical 1 1 1 Affinity Capture-MS
PRP43 YGL120C RNA helicase in the DEAH-box family physical 1 1 1 Affinity Capture-MS
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing physical 1 1 1 Affinity Capture-MS
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 1 1 1 Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex physical 1 1 1 Affinity Capture-MS
UTP22 YGR090W Component of the small-subunit processome physical 1 1 1 Affinity Capture-MS
RPC53 YDL150W RNA polymerase III subunit C53 physical 1 1 1 Biochemical Activity
KNS1 YLL019C Protein kinase involved in negative regulation of PolIII transcription physical 1 1 1 Biochemical Activity
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
YPD1 YDL235C Osmotic stress-responsive phosphorelay intermediate sensor protein genetic 1 1 1 Positive Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Positive Genetic
YSR3 YKR053C Dihydrosphingosine 1-phosphate phosphatase genetic 1 1 1 Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Positive Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Positive Genetic
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Positive Genetic
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes genetic 1 1 1 Synthetic Lethality
SHR3 YDL212W Endoplasmic reticulum packaging chaperone genetic 1 1 1 Negative Genetic
NRG1 YDR043C Transcriptional repressor genetic 1 1 1 Positive Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Negative Genetic
TOG1 YER184C Transcriptional activator of oleate genes genetic 1 1 1 Positive Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
RLM1 YPL089C MADS-box transcription factor genetic 1 1 1 Negative Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Positive Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Positive Genetic
YGL081W YGL081W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
PHO5 YBR093C Repressible acid phosphatase genetic 1 1 1 Synthetic Growth Defect
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RRT2 YBR246W Methylesterase performing penultimate step of diphthamide biosynthesis genetic 1 1 1 Synthetic Growth Defect
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Synthetic Growth Defect
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Synthetic Growth Defect
VPS60 YDR486C Protein involved in late endosome to vacuole transport genetic 1 1 1 Synthetic Growth Defect
PKH1 YDR490C Serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Synthetic Growth Defect
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Synthetic Growth Defect
RPE1 YJL121C D-ribulose-5-phosphate 3-epimerase genetic 1 1 1 Synthetic Growth Defect
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Synthetic Growth Defect
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Synthetic Growth Defect
LAM6 YLR072W Sterol transporter that transfers sterols between membranes genetic 1 1 1 Synthetic Growth Defect
STM1 YLR150W Protein required for optimal translation under nutrient stress genetic 1 1 1 Synthetic Growth Defect
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Growth Defect
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Synthetic Growth Defect
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Synthetic Growth Defect
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 1 1 1 Synthetic Growth Defect
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Synthetic Growth Defect
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 1 1 1 Synthetic Growth Defect
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Synthetic Growth Defect
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 1 1 1 Synthetic Growth Defect
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) genetic 1 1 1 Synthetic Growth Defect
ZTA1 YBR046C NADPH-dependent quinone reductase genetic 1 1 1 Synthetic Growth Defect
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Synthetic Growth Defect
TMA22 YJR014W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Synthetic Growth Defect
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Synthetic Growth Defect
SAL1 YNL083W ADP/ATP transporter genetic 1 1 1 Synthetic Growth Defect
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Positive Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Positive Genetic
RPL6B YLR448W Ribosomal 60S subunit protein L6B genetic 1 1 1 Positive Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Positive Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
SPE3 YPR069C Spermidine synthase genetic 1 1 1 Positive Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Positive Genetic
SUV3 YPL029W ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
MTR4 YJL050W RNA duplex-sensing translocase genetic 1 1 1 Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
PDX3 YBR035C Pyridoxine (pyridoxamine) phosphate oxidase genetic 1 1 1 Negative Genetic
MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
NPP1 YCR026C Nucleotide pyrophosphatase/phosphodiesterase genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TCM62 YBR044C Protein involved in assembly of the succinate dehydrogenase complex genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
YDR249C YDR249C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
XBP1 YIL101C Transcriptional repressor genetic 1 1 1 Negative Genetic
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p genetic 1 1 1 Negative Genetic
VTH1 YIL173W Putative membrane glycoprotein genetic 1 1 1 Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
YAK1 YJL141C Serine-threonine protein kinase genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
VAC14 YLR386W Enzyme regulator genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
MRPL39 YML009C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Negative Genetic
PUB1 YNL016W Poly (A)+ RNA-binding protein genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Negative Genetic
YOR365C YOR365C Putative protein involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
LEE1 YPL054W Zinc-finger protein of unknown function genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
YPR015C YPR015C Putative zinc finger transcription factor genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Positive Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Negative Genetic
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin genetic 1 1 1 Positive Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein genetic 1 1 1 Synthetic Growth Defect
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 1 1 1 Negative Genetic
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 1 1 1 Biochemical Activity
ACS1 YAL054C Acetyl-coA synthetase isoform genetic 1 1 1 Negative Genetic
FPK1 YNR047W Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 1 1 1 Synthetic Growth Defect
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Negative Genetic
GBP2 YCL011C Poly(A+) RNA-binding protein physical 1 1 1 Affinity Capture-MS
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
ATG13 YPR185W Regulatory subunit of the Atg1p signaling complex genetic 1 1 1 Negative Genetic
GZF3 YJL110C GATA zinc finger protein genetic 1 1 1 Synthetic Growth Defect
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Synthetic Growth Defect
IPL1 YPL209C Aurora kinase of chromosomal passenger complex physical 1 1 1 Two-hybrid
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Synthetic Growth Defect
ATG23 YLR431C Peripheral membrane protein required for autophagy and CVT genetic 1 1 1 Synthetic Growth Defect
ELO3 YLR372W Elongase genetic 1 1 1 Synthetic Growth Defect
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
HRB1 YNL004W Poly(A+) RNA-binding protein physical 1 1 1 Affinity Capture-MS
HSF1 YGL073W Trimeric heat shock transcription factor physical 1 1 1 Biochemical Activity
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Positive Genetic
BUD6 YLR319C Actin- and formin-interacting protein genetic 1 1 1 Synthetic Growth Defect
DPH6 YLR143W Diphthamide synthetase genetic 1 1 1 Synthetic Growth Defect
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Positive Genetic
ABZ1 YNR033W Para-aminobenzoate (PABA) synthase genetic 1 1 1 Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Negative Genetic
DUS3 YLR401C Dihydrouridine synthase genetic 1 1 1 Synthetic Growth Defect
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
AIM22 YJL046W Lipoate-protein ligase genetic 1 1 1 Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Negative Genetic
ACB1 YGR037C Acyl-CoA-binding protein physical 1 1 1 Affinity Capture-MS
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Synthetic Growth Defect
DIN7 YDR263C Mitochondrial nuclease functioning in DNA repair and replication genetic 1 1 1 Negative Genetic
GLN4 YOR168W Glutamine tRNA synthetase genetic 1 1 1 Negative Genetic
ATG21 YPL100W Phosphoinositide binding protein genetic 1 1 1 Negative Genetic
CMK2 YOL016C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
ECM7 YLR443W Putative integral membrane protein with a role in calcium uptake genetic 1 1 1 Negative Genetic
GIS1 YDR096W Histone demethylase and transcription factor genetic 1 1 1 Negative Genetic
JJJ3 YJR097W Iron-binding protein genetic 1 1 1 Synthetic Growth Defect
COM2 YER130C Transcription factor that binds IME1 Upstream Activation Signal (UAS) genetic 1 1 1 Synthetic Growth Defect
BAP2 YBR068C High-affinity leucine permease genetic 1 1 1 Synthetic Growth Defect
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
INO1 YJL153C Inositol-3-phosphate synthase genetic 1 1 1 Negative Genetic
KHA1 YJL094C Putative K+/H+ antiporter genetic 1 1 1 Negative Genetic
ATH1 YPR026W Acid trehalase required for utilization of extracellular trehalose genetic 1 1 1 Negative Genetic
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Negative Genetic
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3 genetic 1 1 1 Positive Genetic
ENV9 YOR246C Conserved oxidoreductase involved in lipid droplet morphology genetic 1 1 1 Synthetic Growth Defect
CTM1 YHR109W Cytochrome c lysine methyltransferase genetic 1 1 1 Negative Genetic