SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
physical |
19 |
5 |
14 |
Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, PCA, Two-hybrid, Two-hybrid, PCA, PCA, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex |
SLN1 |
YIL147C |
Transmembrane histidine phosphotransfer kinase and osmosensor |
physical |
14 |
4 |
11 |
Co-crystal Structure, Two-hybrid, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Two-hybrid, Biochemical Activity, Biochemical Activity, Co-crystal Structure, Biochemical Activity, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
physical |
5 |
4 |
5 |
Biochemical Activity, Affinity Capture-Western, Two-hybrid, Biochemical Activity, PCA |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
4 |
2 |
3 |
Synthetic Rescue, Positive Genetic, Synthetic Rescue, Synthetic Rescue |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
3 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
PTP2 |
YOR208W |
Phosphotyrosine-specific phosphatase |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ATG14 |
YBR128C |
Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MBP1 |
YDL056W |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
PIL1 |
YGR086C |
Eisosome core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PSK1 |
YAL017W |
PAS domain-containing serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SKI3 |
YPR189W |
Ski complex component and TPR protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPQ1 |
YPL179W |
Protein phosphatase that regulates the mating response |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMK1 |
YFR014C |
Calmodulin-dependent protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
FAR1 |
YJL157C |
CDK inhibitor and nuclear anchor |
genetic |
1 |
1 |
1 |
Positive Genetic |
KDX1 |
YKL161C |
Protein kinase |
physical |
1 |
1 |
1 |
PCA |
TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
INM1 |
YHR046C |
Inositol monophosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
DMA1 |
YHR115C |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTP3 |
YER075C |
Phosphotyrosine-specific protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PTC7 |
YHR076W |
Type 2C serine/threonine protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPE1 |
YHR075C |
Protein with carboxyl methyl esterase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
1 |
1 |
1 |
PCA |
YTM1 |
YOR272W |
Ribosomal assembly factor and 66S pre-ribosomal particle constituent |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YSR3 |
YKR053C |
Dihydrosphingosine 1-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCK1 |
YGL158W |
Protein kinase involved in oxidative stress response |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
FPK1 |
YNR047W |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
1 |
1 |
1 |
Positive Genetic |
TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIM11 |
YMR139W |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KKQ8 |
YKL168C |
Putative serine/threonine protein kinase with unknown cellular role |
genetic |
1 |
1 |
1 |
Positive Genetic |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PCL2 |
YDL127W |
Cyclin, interacts with cyclin-dependent kinase Pho85p |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA2 |
YNL056W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APN1 |
YKL114C |
Major apurinic/apyrimidinic endonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PHO80 |
YOL001W |
Cyclin |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TCO89 |
YPL180W |
Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAX1 |
YOR301W |
Protein involved in establishing bud site selection |
physical |
1 |
1 |
1 |
PCA |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FRK1 |
YPL141C |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
VID30 |
YGL227W |
Central component of GID Complex, involved in FBPase degradation |
genetic |
1 |
1 |
1 |
Positive Genetic |
OCA4 |
YCR095C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Positive Genetic |
GUT1 |
YHL032C |
Glycerol kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
KIN4 |
YOR233W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Positive Genetic |
SKS1 |
YPL026C |
Putative serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TWF1 |
YGR080W |
Twinfilin |
genetic |
1 |
1 |
1 |
Positive Genetic |
DAK1 |
YML070W |
Dihydroxyacetone kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
LCB4 |
YOR171C |
Sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRK1 |
YDL079C |
Glycogen synthase kinase 3 (GSK-3) homolog |
genetic |
1 |
1 |
1 |
Positive Genetic |
VHS1 |
YDR247W |
Cytoplasmic serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PHO3 |
YBR092C |
Constitutively expressed acid phosphatase similar to Pho5p |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR1 |
YJR110W |
Phosphatidylinositol 3-phosphate (PI3P) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YCH1 |
YGR203W |
Phosphatase with sequence similarity to Mih1p |
genetic |
1 |
1 |
1 |
Positive Genetic |