CMD1 |
YBR109C |
Calmodulin |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Biochemical Activity |
PDR12 |
YPL058C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
3 |
3 |
2 |
Phenotypic Suppression, Dosage Rescue, Synthetic Rescue |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-MS |
CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
GRX4 |
YER174C |
Glutathione-dependent oxidoreductase and glutathione S-transferase |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
SDL1 |
YIL167W |
Blocked reading frame otherwise encoding L-serine dehydratase |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
PET122 |
YER153C |
Mitochondrial translational activator specific for the COX3 mRNA |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
ERS1 |
YCR075C |
Protein involved in cystine transport |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
CDA1 |
YLR307W |
Chitin deacetylase |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRPL1 |
YDR116C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DIT2 |
YDR402C |
N-formyltyrosine oxidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CDC40 |
YDR364C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
BFR2 |
YDR299W |
Component of the SSU and 90S preribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
physical |
1 |
1 |
1 |
Biochemical Activity |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Reconstituted Complex |
AIM21 |
YIR003W |
Subunit of a complex that associates with actin filaments |
physical |
1 |
1 |
1 |
Biochemical Activity |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Biochemical Activity |
CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADA2 |
YDR448W |
Transcription coactivator |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
physical |
1 |
1 |
1 |
Biochemical Activity |
BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
physical |
1 |
1 |
1 |
Biochemical Activity |
BSP1 |
YPR171W |
Adapter that links synaptojanins to the cortical actin cytoskeleton |
physical |
1 |
1 |
1 |
Biochemical Activity |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
AKL1 |
YBR059C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIP2 |
YGL208W |
One of three alternate beta subunits of the Snf1 kinase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
TOM71 |
YHR117W |
Mitochondrial outer membrane protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Biochemical Activity |
PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
physical |
1 |
1 |
1 |
Biochemical Activity |
PHA2 |
YNL316C |
Prephenate dehydratase |
physical |
1 |
1 |
1 |
Biochemical Activity |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPL39 |
YJL189W |
Ribosomal 60S subunit protein L39 |
physical |
1 |
1 |
1 |
Biochemical Activity |
MMF1 |
YIL051C |
Mitochondrial protein required for transamination of isoleucine |
physical |
1 |
1 |
1 |
Biochemical Activity |
IDS2 |
YJL146W |
Protein involved in modulation of Ime2p activity during meiosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
YHR112C |
YHR112C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
SSF2 |
YDR312W |
Protein required for ribosomal large subunit maturation |
physical |
1 |
1 |
1 |
Biochemical Activity |
TMT1 |
YER175C |
Trans-aconitate methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
SRP40 |
YKR092C |
Nucleolar serine-rich protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPS26B |
YER131W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
MGA1 |
YGR249W |
Protein similar to heat shock transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
physical |
1 |
1 |
1 |
Biochemical Activity |
KXD1 |
YGL079W |
Subunit of the BLOC-1 complex involved in endosomal maturation |
physical |
1 |
1 |
1 |
Biochemical Activity |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
physical |
1 |
1 |
1 |
Biochemical Activity |
IGD1 |
YFR017C |
Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
SER33 |
YIL074C |
3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase |
physical |
1 |
1 |
1 |
Biochemical Activity |
DRE2 |
YKR071C |
Component of the cytosolic Fe-S protein assembly (CIA) machinery |
physical |
1 |
1 |
1 |
Biochemical Activity |
NTH1 |
YDR001C |
Neutral trehalase, degrades trehalose |
physical |
1 |
1 |
1 |
Biochemical Activity |
CRZ1 |
YNL027W |
Transcription factor, activates transcription of stress response genes |
physical |
1 |
1 |
1 |
Biochemical Activity |
MSN5 |
YDR335W |
Karyopherin |
physical |
1 |
1 |
1 |
Biochemical Activity |
OXA1 |
YER154W |
Mitochondrial inner membrane insertase |
physical |
1 |
1 |
1 |
Biochemical Activity |
DBP9 |
YLR276C |
DEAD-box protein required for 27S rRNA processing |
physical |
1 |
1 |
1 |
Biochemical Activity |
PGM1 |
YKL127W |
Phosphoglucomutase, minor isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
PIB2 |
YGL023C |
Phosphatidylinositol 3-phosphate binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
physical |
1 |
1 |
1 |
Biochemical Activity |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
physical |
1 |
1 |
1 |
Biochemical Activity |
NOP53 |
YPL146C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
STB3 |
YDR169C |
Ribosomal RNA processing element (RRPE)-binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
REX2 |
YLR059C |
3'-5' RNA exonuclease |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
NTH2 |
YBR001C |
Putative neutral trehalase, required for thermotolerance |
physical |
1 |
1 |
1 |
Biochemical Activity |
DOT5 |
YIL010W |
Nuclear thiol peroxidase |
physical |
1 |
1 |
1 |
Biochemical Activity |
DIF1 |
YLR437C |
Protein that regulates nuclear import of Rnr2p and Rnr4p |
physical |
1 |
1 |
1 |
Biochemical Activity |
VHS3 |
YOR054C |
Negative regulatory subunit of protein phosphatase 1 Ppz1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
POX1 |
YGL205W |
Fatty-acyl coenzyme A oxidase |
physical |
1 |
1 |
1 |
Biochemical Activity |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
QCR6 |
YFR033C |
Subunit 6 of the ubiquinol cytochrome-c reductase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
NPA3 |
YJR072C |
Member of the conserved GPN-loop GTPase family |
physical |
1 |
1 |
1 |
Biochemical Activity |
GIP2 |
YER054C |
Putative regulatory subunit of protein phosphatase Glc7p |
physical |
1 |
1 |
1 |
Biochemical Activity |
LEU3 |
YLR451W |
Zinc-knuckle transcription factor, repressor and activator |
physical |
1 |
1 |
1 |
Biochemical Activity |
MGS1 |
YNL218W |
Protein with DNA-dependent ATPase and ssDNA annealing activities |
physical |
1 |
1 |
1 |
Biochemical Activity |
YLR030W |
YLR030W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
PRX1 |
YBL064C |
Mitochondrial peroxiredoxin with thioredoxin peroxidase activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
STR3 |
YGL184C |
Peroxisomal cystathionine beta-lyase |
physical |
1 |
1 |
1 |
Biochemical Activity |
MAG1 |
YER142C |
3-methyl-adenine DNA glycosylase |
physical |
1 |
1 |
1 |
Biochemical Activity |
SIP5 |
YMR140W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
FOX2 |
YKR009C |
3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase |
physical |
1 |
1 |
1 |
Biochemical Activity |
SSE2 |
YBR169C |
Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family |
physical |
1 |
1 |
1 |
Biochemical Activity |
TPO1 |
YLL028W |
Polyamine transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Biochemical Activity |
NNR2 |
YKL151C |
Widely-conserved NADHX dehydratase |
physical |
1 |
1 |
1 |
Biochemical Activity |
YGL039W |
YGL039W |
Aldehyde reductase |
physical |
1 |
1 |
1 |
Biochemical Activity |
PDS1 |
YDR113C |
Securin |
physical |
1 |
1 |
1 |
Biochemical Activity |
PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
VFA1 |
YER128W |
Protein that interacts with Vps4p and has a role in vacuolar sorting |
physical |
1 |
1 |
1 |
Biochemical Activity |
GCV1 |
YDR019C |
T subunit of the mitochondrial glycine decarboxylase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
NSR1 |
YGR159C |
Nucleolin, nucleolar protein that binds nuclear localization sequences |
physical |
1 |
1 |
1 |
Biochemical Activity |
FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
physical |
1 |
1 |
1 |
Biochemical Activity |
JJJ1 |
YNL227C |
Co-chaperone that stimulates the ATPase activity of Ssa1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
EHT1 |
YBR177C |
Octanoyl-CoA:ethanol acyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
MNR2 |
YKL064W |
Vacuolar membrane protein required for magnesium homeostasis |
physical |
1 |
1 |
1 |
Biochemical Activity |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Biochemical Activity |
YGR130C |
YGR130C |
Component of the eisosome with unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
physical |
1 |
1 |
1 |
Biochemical Activity |
COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
PRM4 |
YPL156C |
Pheromone-regulated protein proposed to be involved in mating |
physical |
1 |
1 |
1 |
Biochemical Activity |
GTT3 |
YEL017W |
Protein of unknown function may be involved in glutathione metabolism |
physical |
1 |
1 |
1 |
Biochemical Activity |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
physical |
1 |
1 |
1 |
Biochemical Activity |
DDI1 |
YER143W |
Aspartic-type endopeptidase |
physical |
1 |
1 |
1 |
Biochemical Activity |
VMA4 |
YOR332W |
Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) |
physical |
1 |
1 |
1 |
Biochemical Activity |
RCF1 |
YML030W |
Cytochrome c oxidase subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
physical |
1 |
1 |
1 |
Biochemical Activity |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
URN1 |
YPR152C |
Protein of unknown function containing WW and FF domains |
physical |
1 |
1 |
1 |
Biochemical Activity |
RGD3 |
YHR182W |
GTPase activating protein (GAP) for Rho3p, involved in cell polarity g |
physical |
1 |
1 |
1 |
Biochemical Activity |
LEO1 |
YOR123C |
Component of the Paf1 complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Biochemical Activity |
ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRP4 |
YDR354W |
Anthranilate phosphoribosyl transferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
MFT1 |
YML062C |
Subunit of the THO complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
physical |
1 |
1 |
1 |
Biochemical Activity |
NBP1 |
YLR457C |
Spindle pole body (SPB) component |
physical |
1 |
1 |
1 |
Biochemical Activity |
SKP1 |
YDR328C |
Evolutionarily conserved kinetochore protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
YBL055C |
YBL055C |
3'-->5' exonuclease and endonuclease with a possible role in apoptosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
SCT1 |
YBL011W |
Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
IRC19 |
YLL033W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
physical |
1 |
1 |
1 |
Biochemical Activity |
GLG2 |
YJL137C |
Glycogenin glucosyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPO26 |
YPR187W |
RNA polymerase subunit ABC23 |
physical |
1 |
1 |
1 |
Biochemical Activity |
NEJ1 |
YLR265C |
DNA end-binding protein required for nonhomologous end joining (NHEJ) |
physical |
1 |
1 |
1 |
Biochemical Activity |
OLE1 |
YGL055W |
Delta(9) fatty acid desaturase |
physical |
1 |
1 |
1 |
Biochemical Activity |
MRF1 |
YGL143C |
Mitochondrial translation release factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
PIR5 |
YJL160C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
NUP49 |
YGL172W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
physical |
1 |
1 |
1 |
Biochemical Activity |
DDR48 |
YMR173W |
DNA damage-responsive protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPL34B |
YIL052C |
Ribosomal 60S subunit protein L34B |
physical |
1 |
1 |
1 |
Biochemical Activity |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Biochemical Activity |
DBR1 |
YKL149C |
RNA lariat debranching enzyme |
physical |
1 |
1 |
1 |
Biochemical Activity |
PDL32 |
YMR087W |
Putative ADP-ribose-1''-monophosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Positive Genetic |
PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
PMU1 |
YKL128C |
Putative phosphomutase |
physical |
1 |
1 |
1 |
Biochemical Activity |
MDM36 |
YPR083W |
Mitochondrial protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
RDS2 |
YPL133C |
Transcription factor involved in regulating gluconeogenesis |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
FRT2 |
YAL028W |
Tail-anchored ER membrane protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
MSP1 |
YGR028W |
Highly-conserved N-terminally anchored AAA-ATPase |
physical |
1 |
1 |
1 |
Biochemical Activity |
ECM3 |
YOR092W |
Non-essential protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CYB5 |
YNL111C |
Cytochrome b5 |
physical |
1 |
1 |
1 |
Reconstituted Complex |
ERG20 |
YJL167W |
Farnesyl pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
physical |
1 |
1 |
1 |
Reconstituted Complex |
FSF1 |
YOR271C |
Putative protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
MES1 |
YGR264C |
Methionyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
NPL4 |
YBR170C |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RAS1 |
YOR101W |
GTPase involved in G-protein signaling in adenylate cyclase activation |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RTR1 |
YER139C |
Dual specificity protein phosphatase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SER1 |
YOR184W |
3-phosphoserine aminotransferase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
YHR033W |
YHR033W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
EFM3 |
YJR129C |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
YNR064C |
YNR064C |
Epoxide hydrolase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
YPT32 |
YGL210W |
Rab family GTPase involved in the exocytic pathway |
physical |
1 |
1 |
1 |
Reconstituted Complex |
YPT7 |
YML001W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RTC3 |
YHR087W |
Protein of unknown function involved in RNA metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
physical |
1 |
1 |
1 |
Biochemical Activity |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPD1 |
YDL235C |
Osmotic stress-responsive phosphorelay intermediate sensor protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRK1 |
YDL079C |
Glycogen synthase kinase 3 (GSK-3) homolog |
genetic |
1 |
1 |
1 |
Positive Genetic |
WWM1 |
YFL010C |
WW domain containing protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
YVH1 |
YIR026C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSY2 |
YNL201C |
Subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HRI1 |
YLR301W |
Protein of unknown function that interacts with Sec72p and Hrr25p |
genetic |
1 |
1 |
1 |
Negative Genetic |
YSP3 |
YOR003W |
Putative precursor of the subtilisin-like protease III |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YGR027W-B |
YGR027W-B |
Retrotransposon TYA Gag and TYB Pol genes |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
DOP1 |
YDR141C |
Protein involved in vesicular transport at trans-Golgi network (TGN) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
MRX16 |
YDR132C |
Protein that associates with the large mitoribosomal subunit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNA4 |
YDL123W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
EAR1 |
YMR171C |
Specificity factor required for Rsp5p-dependent ubiquitination |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
TGL4 |
YKR089C |
Multifunctional lipase/hydrolase/phospholipase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
HNM1 |
YGL077C |
Plasma membrane transporter for choline, ethanolamine, and carnitine |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
PEX10 |
YDR265W |
Peroxisomal membrane E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
RAD26 |
YJR035W |
Protein involved in transcription-coupled nucleotide excision repair |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
GEA2 |
YEL022W |
Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRE8 |
YML092C |
Alpha 2 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIM23 |
YNR017W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Positive Genetic |
MTR10 |
YOR160W |
Nuclear import receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
YDR524C-B |
YDR524C-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
GTA1 |
YEL043W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YER187W |
YER187W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAP190 |
YKR028W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAP1 |
YLR256W |
Zinc finger transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
PHO85 |
YPL031C |
Cyclin-dependent kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNU23 |
YDL098C |
Component of the U4/U6.U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAL1 |
YDR021W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC25 |
YER018C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEN2 |
YLR105C |
Subunit of the tRNA splicing endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP8 |
YOL144W |
Nucleolar protein required for 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRP21 |
YBL090W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL32 |
YCR003W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
EGO2 |
YCR075W-A |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDL124W |
YDL124W |
NADPH-dependent alpha-keto amide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UGX2 |
YDL169C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL036W |
YGL036W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR153W |
YGR153W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMT4 |
YJR143C |
Protein O-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR230W-A |
YMR230W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL033W |
YNL033W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP10 |
YDR106W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
APT1 |
YML022W |
Adenine phosphoribosyltransferase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC123 |
YLR215C |
Assembly factor for the eIF2 translation initiation factor complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
ALY2 |
YJL084C |
Alpha arrestin, Ub-ligase adaptor for Rsp5p |
physical |
1 |
1 |
1 |
Biochemical Activity |
APC9 |
YLR102C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
physical |
1 |
1 |
1 |
Biochemical Activity |
CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC31 |
YOR257W |
Calcium-binding component of the spindle pole body (SPB) half-bridge |
physical |
1 |
1 |
1 |
Biochemical Activity |
ATG8 |
YBL078C |
Ub-like protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
BIK1 |
YCL029C |
Microtubule-associated protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
BUD6 |
YLR319C |
Actin- and formin-interacting protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
AZF1 |
YOR113W |
Zinc-finger transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
CBP1 |
YJL209W |
Mitochondrial protein, regulator of COB mRNA stability and translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
ABZ1 |
YNR033W |
Para-aminobenzoate (PABA) synthase |
physical |
1 |
1 |
1 |
Biochemical Activity |
AVT1 |
YJR001W |
Vacuolar transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
AQY3 |
YFL054C |
Putative channel-like protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
ATG21 |
YPL100W |
Phosphoinositide binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
AIM29 |
YKR074W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
ALO1 |
YML086C |
D-Arabinono-1,4-lactone oxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
AIF1 |
YNR074C |
Mitochondrial cell death effector |
genetic |
1 |
1 |
1 |
Positive Genetic |