Standard name Systematic name Name description Description
OXA1 YER154W Mitochondrial inner membrane insertase Mitochondrial inner membrane insertase; mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane; also has a role in insertion of carrier proteins into the inner membrane; acts as a voltage-gated ion channel, activated by substrate peptides; interacts with mitochondrial ribosomes; conserved from bacteria to animals
Visualize the interactome of OXA1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1/S 43

CYCLoPs localization & abundance

WT1 WT2 WT3
Golgi 0.052 0.095 NaN
Mito 0.872 0.859 0.936
Nuc Periphery 0.052 NaN 0.067
Nucleolus 0.080 NaN 0.053
Vac/Vac Memb 0.128 0.127 NaN

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 6550

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
OXA1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor genetic 4 1 4 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
MRP20 YDR405W Mitochondrial ribosomal protein of the large subunit physical 3 2 3 Affinity Capture-Western, Affinity Capture-Western, Proximity Label-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 3 1 3 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
MRPL40 YPL173W Mitochondrial ribosomal protein of the large subunit physical 3 2 2 Affinity Capture-Western, Affinity Capture-Western, Proximity Label-MS
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
TIM23 YNR017W Essential component of the TIM23 complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
TIM50 YPL063W Essential component of the TIM23 complex physical 2 2 2 Affinity Capture-Western, Proximity Label-MS
COX2 Q0250 Subunit II of cytochrome c oxidase (Complex IV) physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
COX3 Q0275 Subunit III of cytochrome c oxidase (Complex IV) physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
ATP6 Q0085 Subunit a of the F0 sector of mitochondrial F1F0 ATP synthase physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
CYT1 YOR065W Cytochrome c1 genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
ILV5 YLR355C Acetohydroxyacid reductoisomerase and mtDNA binding protein genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
DJP1 YIR004W ER-associated chaperone involved in protein targeting physical 2 2 1 Reconstituted Complex, Protein-peptide
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 2 2 1 Phenotypic Suppression, Phenotypic Enhancement
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 2 2 1 Synthetic Rescue, Dosage Rescue
MGR3 YMR115W Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 2 2 1 Synthetic Rescue, Dosage Rescue
OLI1 Q0130 F0-ATP synthase subunit c (ATPase-associated proteolipid) physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor physical 2 1 1 Proximity Label-MS, Proximity Label-MS
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SKN7 YHR206W Nuclear response regulator and transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AIM25 YJR100C Mitochondria protein of unknown function physical 1 1 1 Proximity Label-MS
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
FMP52 YER004W Protein of unknown function physical 1 1 1 Proximity Label-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
CDC45 YLR103C DNA replication initiation factor genetic 1 1 1 Negative Genetic
COX4 YGL187C Subunit IV of cytochrome c oxidase physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
MRP21 YBL090W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Proximity Label-MS
MRH4 YGL064C Mitochondrial ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
MRPL15 YLR312W-A Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
MRPL3 YMR024W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
ATP4 YPL078C Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-Western
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
GUF1 YLR289W Mitochondrial matrix GTPase genetic 1 1 1 Synthetic Growth Defect
CBP3 YPL215W Mitochondrial protein required for assembly of cytochrome bc1 complex physical 1 1 1 Proximity Label-MS
GIS4 YML006C CAAX box containing protein of unknown function genetic 1 1 1 Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 1 1 1 Negative Genetic
CBP6 YBR120C Mitochondrial protein required for translation of the COB mRNA physical 1 1 1 Proximity Label-MS
ARF2 YDL137W ADP-ribosylation factor genetic 1 1 1 Negative Genetic
OMS1 YDR316W Protein integral to the mitochondrial membrane physical 1 1 1 Proximity Label-MS
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 1 1 1 Dosage Rescue
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion genetic 1 1 1 Synthetic Growth Defect
NDE1 YMR145C Mitochondrial external NADH dehydrogenase physical 1 1 1 Proximity Label-MS
DUF1 YOL087C Ubiquitin-binding protein of unknown function genetic 1 1 1 Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component physical 1 1 1 Proximity Label-MS
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Dosage Rescue
ATP5 YDR298C Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-Western
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation genetic 1 1 1 Negative Genetic
COX2 Q0250 Subunit II of cytochrome c oxidase (Complex IV) genetic 1 1 1 Synthetic Rescue
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
COX18 YGR062C Protein required for membrane insertion of C-terminus of Cox2p genetic 1 1 1 Dosage Rescue
COX1 Q0045 Subunit I of cytochrome c oxidase (Complex IV) physical 1 1 1 Affinity Capture-Western
HAP4 YKL109W Transcription factor genetic 1 1 1 Dosage Rescue
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 1 1 1 Negative Genetic
ECM27 YJR106W Protein involved in calcium homeostasis and exit from quiescence genetic 1 1 1 Negative Genetic
VAR1 Q0140 Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-Western
OXA1 YER154W Mitochondrial inner membrane insertase physical 1 1 1 Affinity Capture-Western
TIM17 YJL143W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-Western
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Protein-RNA
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer physical 1 1 1 Protein-RNA
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
PAM16 YJL104W Subunit of the import motor (PAM complex) physical 1 1 1 Proximity Label-MS
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) physical 1 1 1 Proximity Label-MS
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
RIM2 YBR192W Mitochondrial pyrimidine nucleotide transporter physical 1 1 1 Proximity Label-MS
SAL1 YNL083W ADP/ATP transporter physical 1 1 1 Proximity Label-MS
SCO1 YBR037C Copper-binding protein of mitochondrial inner membrane physical 1 1 1 Proximity Label-MS
SDH3 YKL141W Subunit of succinate dehydrogenase and of TIM22 translocase physical 1 1 1 Proximity Label-MS
SDH4 YDR178W Membrane anchor subunit of succinate dehydrogenase (SDH) physical 1 1 1 Proximity Label-MS
SHE9 YDR393W Protein required for normal mitochondrial morphology physical 1 1 1 Proximity Label-MS
SHY1 YGR112W Mitochondrial inner membrane protein required for complex IV assembly physical 1 1 1 Proximity Label-MS
TAM41 YGR046W Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase) physical 1 1 1 Proximity Label-MS
TDH1 YJL052W Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 physical 1 1 1 Proximity Label-MS
TIM54 YJL054W Component of the mitochondrial TIM22 complex physical 1 1 1 Proximity Label-MS
YLH47 YPR125W Mitochondrial inner membrane protein physical 1 1 1 Proximity Label-MS
YME1 YPR024W Catalytic subunit of i-AAA protease complex physical 1 1 1 Proximity Label-MS
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component physical 1 1 1 Proximity Label-MS
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Dosage Rescue
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-RNA
PDR3 YBL005W Transcriptional activator of the pleiotropic drug resistance network genetic 1 1 1 Synthetic Growth Defect
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Synthetic Rescue
PSD2 YGR170W Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes genetic 1 1 1 Phenotypic Enhancement
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Synthetic Growth Defect
RMD9 YGL107C Mitochondrial protein that controls mitochondrial gene expression genetic 1 1 1 Dosage Rescue
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Synthetic Growth Defect
USB1 YLR132C Putative poly(U)-specific 3'-to-5' RNA exonuclease genetic 1 1 1 Dosage Rescue
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly genetic 1 1 1 Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
SPG5 YMR191W Protein required for proteasome assembly during quiescence genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
YCR090C YCR090C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL13A YDL082W Ribosomal 60S subunit protein L13A genetic 1 1 1 Negative Genetic
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
TOM7 YNL070W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
PMS1 YNL082W ATP-binding protein required for mismatch repair genetic 1 1 1 Negative Genetic
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 1 1 1 Negative Genetic
YOR008C-A YOR008C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SRL1 YOR247W Mannoprotein that exhibits a tight association with the cell wall genetic 1 1 1 Negative Genetic
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane genetic 1 1 1 Synthetic Lethality
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
COB Q0105 Cytochrome b physical 1 1 1 Affinity Capture-Western
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter physical 1 1 1 Proximity Label-MS
MEU1 YLR017W Methylthioadenosine phosphorylase (MTAP) physical 1 1 1 Proximity Label-MS
CIT1 YNR001C Mitochondrial citrate synthase genetic 1 1 1 Negative Genetic
COX15 YER141W Heme a synthase physical 1 1 1 Proximity Label-MS
DSF2 YBR007C Deletion suppressor of mpt5 mutation genetic 1 1 1 Negative Genetic
GEP7 YGL057C Protein of unknown function physical 1 1 1 Proximity Label-MS
CHA1 YCL064C Catabolic L-serine (L-threonine) deaminase physical 1 1 1 Proximity Label-MS
INA22 YIR024C F1F0 ATP synthase peripheral stalk assembly factor genetic 1 1 1 Negative Genetic
INA17 YPL099C F1F0 ATPase synthase peripheral stalk assembly factor physical 1 1 1 Proximity Label-MS
MSS51 YLR203C Specific translational activator for the mitochondrial COX1 mRNA physical 1 1 1 Proximity Label-MS
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex physical 1 1 1 Proximity Label-MS
CMK2 YOL016C Calmodulin-dependent protein kinase physical 1 1 1 Reconstituted Complex
NGL3 YML118W 3'-5' exonuclease specific for poly-A RNAs genetic 1 1 1 Negative Genetic
AIM39 YOL053W Protein of unknown function physical 1 1 1 Proximity Label-MS
MRX9 YDL027C Protein that associates with mitochondrial ribosome physical 1 1 1 Proximity Label-MS
COX10 YPL172C Heme A:farnesyltransferase physical 1 1 1 Proximity Label-MS
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor physical 1 1 1 Proximity Label-MS
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor genetic 1 1 1 Synthetic Growth Defect
COX11 YPL132W Protein required for delivery of copper to Cox1p physical 1 1 1 Proximity Label-MS
COA1 YIL157C Mitochondrial inner membrane protein physical 1 1 1 Proximity Label-MS
FMP25 YLR077W Protein required for assembly of respiratory complex III physical 1 1 1 Proximity Label-MS
OAC1 YKL120W Mitochondrial inner membrane transporter physical 1 1 1 Proximity Label-MS
COX20 YDR231C Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
GRX7 YBR014C Cis-golgi localized monothiol glutaredoxin genetic 1 1 1 Negative Genetic
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter physical 1 1 1 Proximity Label-MS
AFG1 YEL052W Protein that may act as a chaperone for cytochrome c oxidase subunits physical 1 1 1 Proximity Label-MS
MCO32 YGR053C Putative protein of unknown function physical 1 1 1 Proximity Label-MS
AIM19 YIL087C Protein of unknown function physical 1 1 1 Proximity Label-MS
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease genetic 1 1 1 Negative Genetic
ODC1 YPL134C Mitochondrial inner membrane transporter physical 1 1 1 Proximity Label-MS
GAS4 YOL132W 1,3-beta-glucanosyltransferase genetic 1 1 1 Negative Genetic
MRX19 YDL183C Protein that may form an active mitochondrial KHE system physical 1 1 1 Proximity Label-MS
AIM24 YJR080C Protein with a role in determining mitochondrial architecture physical 1 1 1 Proximity Label-MS
NAT2 YGR147C Protein of unknown function physical 1 1 1 Proximity Label-MS
NDI1 YML120C NADH:ubiquinone oxidoreductase physical 1 1 1 Proximity Label-MS
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
MRX20 YFR045W Putative mitochondrial transport protein physical 1 1 1 Proximity Label-MS
MME1 YMR166C Transporter of the mitochondrial inner membrane that exports magnesium physical 1 1 1 Proximity Label-MS
MRX4 YPL168W Protein that associates with mitochondrial ribosome physical 1 1 1 Proximity Label-MS
MRX15 YNR040W Membrane-associated mitoribosome receptor physical 1 1 1 Proximity Label-MS
MMT1 YMR177W Putative metal transporter involved in mitochondrial iron accumulation physical 1 1 1 Proximity Label-MS