Standard name Systematic name Name description Description
OMS1 YDR316W Protein integral to the mitochondrial membrane Protein integral to the mitochondrial membrane; has a conserved methyltransferase motif and is predicted to be an RNA methyltransferase; multicopy suppressor of respiratory defects caused by OXA1 mutations
Visualize the interactome of OMS1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.962 0.821 0.901
Vac/Vac Memb 0.108 0.154 0.070
Golgi NaN 0.064 NaN

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
OMS1 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
KIN4 YOR233W Serine/threonine protein kinase genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 4 1 4 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
JID1 YPR061C Probable Hsp40p co-chaperone genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CDC73 YLR418C Component of the Paf1p complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NGL2 YMR285C Protein involved in 5.8S rRNA processing genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SSA3 YBL075C ATPase involved in protein folding and the response to stress genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
STF1 YDL130W-A Protein involved in regulation of the mitochondrial F1F0-ATP synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
POX1 YGL205W Fatty-acyl coenzyme A oxidase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PFS1 YHR185C Sporulation protein required for prospore membrane formation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SMT1 YJL147C Translational repressor of the mitochondrial ATP6/8 mRNA genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RHO4 YKR055W Non-essential small GTPase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
TMH18 YPR098C Mitochondrial protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
INO2 YDR123C Transcription factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MTO1 YGL236C Mitochondrial protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MSC1 YML128C Protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MSC6 YOR354C Multicopy suppressor of HER2 involved in mitochondrial translation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MRX15 YNR040W Membrane-associated mitoribosome receptor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDA2 YLR308W Chitin deacetylase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MSS51 YLR203C Specific translational activator for the mitochondrial COX1 mRNA physical 3 2 1 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 2 1 2 Negative Genetic, Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 2 1 2 Negative Genetic, Negative Genetic
HGH1 YGR187C Chaperone protein for translation factor eEF2 genetic 2 1 2 Negative Genetic, Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
MRP13 YGR084C Mitochondrial ribosomal protein of the small subunit genetic 2 1 2 Negative Genetic, Negative Genetic
EHD3 YDR036C 3-hydroxyisobutyryl-CoA hydrolase genetic 2 1 2 Negative Genetic, Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 2 1 2 Negative Genetic, Negative Genetic
MRPL39 YML009C Mitochondrial ribosomal protein of the large subunit genetic 2 1 2 Negative Genetic, Negative Genetic
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 2 1 2 Negative Genetic, Negative Genetic
SOR2 YDL246C Sorbitol dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 2 1 2 Negative Genetic, Negative Genetic
YCR090C YCR090C Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
PAR32 YDL173W Low complexity protein genetic 2 1 2 Negative Genetic, Negative Genetic
YDL157C YDL157C Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
QRI7 YDL104C Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 2 1 2 Negative Genetic, Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 2 1 2 Negative Genetic, Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 2 1 2 Negative Genetic, Negative Genetic
PIR5 YJL160C Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
PRY1 YJL079C Lipid binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
PAM17 YKR065C Constituent of the TIM23 complex genetic 2 1 2 Negative Genetic, Negative Genetic
SRL3 YKR091W Repressor of transcription at Start genetic 2 1 2 Negative Genetic, Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 2 1 2 Positive Genetic, Positive Genetic
TOM7 YNL070W Component of the TOM (translocase of outer membrane) complex genetic 2 1 2 Negative Genetic, Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 2 1 2 Negative Genetic, Negative Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SPE3 YPR069C Spermidine synthase genetic 2 1 2 Negative Genetic, Negative Genetic
YPR172W YPR172W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
PAU10 YDR542W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
RIP1 YEL024W Ubiquinol-cytochrome-c reductase genetic 2 1 2 Positive Genetic, Positive Genetic
YEA6 YEL006W Mitochondrial NAD+ transporter genetic 2 1 2 Negative Genetic, Negative Genetic
YPT31 YER031C Rab family GTPase genetic 2 1 2 Negative Genetic, Negative Genetic
UBC6 YER100W Ubiquitin-conjugating enzyme involved in ERAD genetic 2 1 2 Positive Genetic, Positive Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family genetic 2 1 2 Negative Genetic, Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 2 Negative Genetic, Negative Genetic
CRP1 YHR146W Protein that binds to cruciform DNA structures genetic 2 1 2 Negative Genetic, Negative Genetic
HAP4 YKL109W Transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 2 1 2 Negative Genetic, Negative Genetic
GPB1 YOR371C Multistep regulator of cAMP-PKA signaling genetic 2 1 2 Negative Genetic, Negative Genetic
HSP12 YFL014W Plasma membrane protein involved in maintaining membrane organization genetic 2 1 2 Negative Genetic, Negative Genetic
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor genetic 2 1 2 Negative Genetic, Negative Genetic
DOS2 YDR068W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
AIM11 YER093C-A Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
AIM39 YOL053W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 2 1 2 Negative Genetic, Negative Genetic
MLO127 YJR039W Mitochondrial protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
COX8 YLR395C Subunit VIII of cytochrome c oxidase (Complex IV) genetic 2 1 2 Negative Genetic, Negative Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 2 1 2 Negative Genetic, Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 2 1 2 Negative Genetic, Negative Genetic
CYT2 YKL087C Cytochrome c1 heme lyase genetic 2 1 2 Negative Genetic, Negative Genetic
MRX4 YPL168W Protein that associates with mitochondrial ribosome genetic 2 1 2 Negative Genetic, Negative Genetic
GYP6 YJL044C GTPase-activating protein (GAP) for yeast Rab family member Ypt6p genetic 2 1 1 Negative Genetic, Negative Genetic
PRX1 YBL064C Mitochondrial peroxiredoxin with thioredoxin peroxidase activity genetic 2 1 1 Negative Genetic, Negative Genetic
SHE1 YBL031W Mitotic spindle protein genetic 2 1 1 Negative Genetic, Negative Genetic
THR4 YCR053W Threonine synthase genetic 2 1 1 Negative Genetic, Negative Genetic
SPO71 YDR104C Meiosis-specific protein required for prospore membrane morphogenesis genetic 2 1 1 Negative Genetic, Negative Genetic
TMS1 YDR105C Vacuolar membrane protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit genetic 2 1 1 Negative Genetic, Negative Genetic
VSB1 YGR125W Vacuolar membrane protein required for uptake and storage of arginine genetic 2 1 1 Negative Genetic, Negative Genetic
YJL068C YJL068C Esterase that can function as an S-formylglutathione hydrolase genetic 2 1 1 Negative Genetic, Negative Genetic
YJR120W YJR120W Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
YKR104W YKR104W Putative transporter of the MRP subfamily genetic 2 1 1 Negative Genetic, Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 2 1 1 Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 1 Negative Genetic, Negative Genetic
PET127 YOR017W Protein with a role in 5'-end processing of mitochondrial RNAs genetic 2 1 1 Negative Genetic, Negative Genetic
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 2 1 1 Negative Genetic, Negative Genetic
SIP4 YJL089W C6 zinc cluster transcriptional activator genetic 2 1 1 Negative Genetic, Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 2 1 1 Negative Genetic, Negative Genetic
DPC29 YGR021W Putative mitochondrial protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
HPA2 YPR193C Tetrameric histone acetyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
ALG1 YBR110W Mannosyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 2 1 1 Negative Genetic, Negative Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 2 1 1 Negative Genetic, Negative Genetic
DFG16 YOR030W Probable multiple transmembrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Negative Genetic
HOL1 YNR055C Putative transporter in the major facilitator superfamily genetic 1 1 1 Negative Genetic
COR1 YBL045C Core subunit of the ubiquinol-cytochrome c reductase complex physical 1 1 1 Affinity Capture-MS
MES1 YGR264C Methionyl-tRNA synthetase genetic 1 1 1 Negative Genetic
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Negative Genetic
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
CCA1 YER168C ATP (CTP):tRNA-specific tRNA nucleotidyltransferase genetic 1 1 1 Negative Genetic
ATP11 YNL315C Molecular chaperone genetic 1 1 1 Positive Genetic
CDC45 YLR103C DNA replication initiation factor genetic 1 1 1 Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Positive Genetic
COX4 YGL187C Subunit IV of cytochrome c oxidase physical 1 1 1 Affinity Capture-MS
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
MRP20 YDR405W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
MRP49 YKL167C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL44 YMR225C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
FYV4 YHR059W Protein of unknown function genetic 1 1 1 Negative Genetic
MRP51 YPL118W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-Western
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Positive Genetic
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Negative Genetic
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
HOS4 YIL112W Subunit of the Set3 complex genetic 1 1 1 Negative Genetic
BSP1 YPR171W Adapter that links synaptojanins to the cortical actin cytoskeleton genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Positive Genetic
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 1 1 1 Negative Genetic
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton genetic 1 1 1 Negative Genetic
FIN1 YDR130C Spindle pole body-related intermediate filament protein genetic 1 1 1 Negative Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 1 1 1 Positive Genetic
HSH49 YOR319W U2-snRNP associated splicing factor genetic 1 1 1 Negative Genetic
GID7 YCL039W Subunit of GID Complex that binds directly to central component Vid30p genetic 1 1 1 Negative Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Positive Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
MCX1 YBR227C Non-proteolytic ATPase of the AAA family genetic 1 1 1 Negative Genetic
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 1 1 1 Negative Genetic
DAK2 YFL053W Dihydroxyacetone kinase physical 1 1 1 Affinity Capture-MS
VMA6 YLR447C Subunit d of the V0 integral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
THI22 YPR121W Protein with similarity to hydroxymethylpyrimidine phosphate kinases physical 1 1 1 Affinity Capture-MS
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex physical 1 1 1 Affinity Capture-MS
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Biochemical Activity
OMS1 YDR316W Protein integral to the mitochondrial membrane physical 1 1 1 Affinity Capture-MS
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
PTC7 YHR076W Type 2C serine/threonine protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 PCA
OXA1 YER154W Mitochondrial inner membrane insertase physical 1 1 1 Proximity Label-MS
OXA1 YER154W Mitochondrial inner membrane insertase genetic 1 1 1 Dosage Rescue
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Negative Genetic
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex genetic 1 1 1 Negative Genetic
RTR1 YER139C Dual specificity protein phosphatase genetic 1 1 1 Negative Genetic
YFR035C YFR035C Putative protein of unknown function genetic 1 1 1 Negative Genetic
PCP1 YGR101W Mitochondrial serine protease genetic 1 1 1 Negative Genetic
YGR122W YGR122W Protein that may be involved in pH regulation genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
YJR011C YJR011C Putative protein of unknown function genetic 1 1 1 Negative Genetic
VPS55 YJR044C Late endosomal protein involved in late endosome to vacuole transport genetic 1 1 1 Negative Genetic
SPA2 YLL021W Component of the polarisome genetic 1 1 1 Negative Genetic
SMF3 YLR034C Putative divalent metal ion transporter involved in iron homeostasis genetic 1 1 1 Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Negative Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Negative Genetic
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 1 1 1 Negative Genetic
RDL2 YOR286W Protein with rhodanese activity genetic 1 1 1 Negative Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
SIP3 YNL257C Putative sterol transfer protein genetic 1 1 1 Negative Genetic
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Positive Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Positive Genetic
YEL1 YBL060W Guanine nucleotide exchange factor specific for Arf3p genetic 1 1 1 Positive Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Positive Genetic
YHR050W-A YHR050W-A Protein of unknown function genetic 1 1 1 Positive Genetic
SRB6 YBR253W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit genetic 1 1 1 Negative Genetic
PNO1 YOR145C Essential nucleolar protein required for pre-18S rRNA processing genetic 1 1 1 Negative Genetic
RRP12 YPL012W Protein required for export of the ribosomal subunits genetic 1 1 1 Negative Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
PRP6 YBR055C Splicing factor genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 1 1 1 Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Negative Genetic
PHS1 YJL097W Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane genetic 1 1 1 Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) genetic 1 1 1 Negative Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
VID24 YBR105C GID Complex regulatory subunit genetic 1 1 1 Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
VBA2 YBR293W Permease of basic amino acids in the vacuolar membrane genetic 1 1 1 Negative Genetic
YCP4 YCR004C Protein of unknown function genetic 1 1 1 Negative Genetic
YIH1 YCR059C Negative regulator of eIF2 kinase Gcn2p genetic 1 1 1 Negative Genetic
RAD18 YCR066W E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
PAU3 YCR104W Member of the seripauperin multigene family genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
RMD1 YDL001W Cytoplasmic protein required for sporulation genetic 1 1 1 Negative Genetic
UBC13 YDR092W E2 ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
TPA1 YER049W Prolyl hydroxylase genetic 1 1 1 Negative Genetic
PTC2 YER089C Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 1 1 1 Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
VAC14 YLR386W Enzyme regulator genetic 1 1 1 Negative Genetic
TSR2 YLR435W Protein with a potential role in pre-rRNA processing genetic 1 1 1 Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
YML119W YML119W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RIM11 YMR139W Protein kinase genetic 1 1 1 Negative Genetic
SIP5 YMR140W Protein of unknown function genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
RNH201 YNL072W Ribonuclease H2 catalytic subunit genetic 1 1 1 Negative Genetic
YOR008C-A YOR008C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
TRP2 YER090W Anthranilate synthase genetic 1 1 1 Negative Genetic
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
VPS45 YGL095C Protein of the Sec1p/Munc-18 family genetic 1 1 1 Negative Genetic
YGL185C YGL185C Putative protein with sequence similar to hydroxyacid dehydrogenases genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
YHR045W YHR045W Putative protein of unknown function genetic 1 1 1 Negative Genetic
UTR1 YJR049C ATP-NADH kinase genetic 1 1 1 Negative Genetic
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
YSR3 YKR053C Dihydrosphingosine 1-phosphate phosphatase genetic 1 1 1 Negative Genetic
YLR412C-A YLR412C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YML053C YML053C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Negative Genetic
SPR1 YOR190W Sporulation-specific exo-1,3-beta-glucanase genetic 1 1 1 Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 1 1 1 Negative Genetic
PET20 YPL159C Mitochondrial protein genetic 1 1 1 Negative Genetic
OYE3 YPL171C Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
SDH2 YLL041C Iron-sulfur protein subunit of succinate dehydrogenase genetic 1 1 1 Positive Genetic
TOS4 YLR183C Putative transcription factor, contains Forkhead Associated domain genetic 1 1 1 Negative Genetic
TBF1 YPL128C Telobox-containing general regulatory factor genetic 1 1 1 Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Negative Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
BUD9 YGR041W Protein involved in bud-site selection physical 1 1 1 Affinity Capture-MS
GSY1 YFR015C Glycogen synthase genetic 1 1 1 Negative Genetic
ADH6 YMR318C NADPH-dependent medium chain alcohol dehydrogenase genetic 1 1 1 Positive Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 1 1 1 Negative Genetic
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Dosage Growth Defect
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
MSN2 YMR037C Stress-responsive transcriptional activator genetic 1 1 1 Negative Genetic
MCM1 YMR043W Transcription factor genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway physical 1 1 1 Affinity Capture-MS
JNM1 YMR294W Component of the yeast dynactin complex genetic 1 1 1 Positive Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
LRG1 YDL240W GTPase-activating protein (GAP) genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Positive Genetic
NNK1 YKL171W Protein kinase genetic 1 1 1 Negative Genetic
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
GDH3 YAL062W NADP(+)-dependent glutamate dehydrogenase genetic 1 1 1 Negative Genetic
ERG5 YMR015C C-22 sterol desaturase genetic 1 1 1 Negative Genetic
ADI1 YMR009W Acireductone dioxygenease involved in methionine salvage pathway genetic 1 1 1 Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Negative Genetic
ATP18 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription genetic 1 1 1 Negative Genetic
DDR2 YOL052C-A Multi-stress response protein genetic 1 1 1 Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
EHT1 YBR177C Octanoyl-CoA:ethanol acyltransferase genetic 1 1 1 Negative Genetic
GLO4 YOR040W Mitochondrial glyoxalase II genetic 1 1 1 Positive Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
COA3 YJL062W-A Mitochondrial protein required for cytochrome c oxidase assembly physical 1 1 1 Affinity Capture-Western
MSS18 YPR134W Nuclear encoded protein needed for splicing of mitochondrial intron genetic 1 1 1 Negative Genetic
GVP36 YIL041W BAR domain protein that localizes to early and late Golgi vesicles genetic 1 1 1 Negative Genetic
KIN82 YCR091W Putative serine/threonine protein kinase genetic 1 1 1 Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
COA1 YIL157C Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-Western
MUP1 YGR055W High affinity methionine permease genetic 1 1 1 Negative Genetic
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p genetic 1 1 1 Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Negative Genetic
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type genetic 1 1 1 Negative Genetic
DAK1 YML070W Dihydroxyacetone kinase genetic 1 1 1 Positive Genetic
FCY22 YER060W-A Putative purine-cytosine permease genetic 1 1 1 Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
ALK1 YGL021W Atypical protein kinase genetic 1 1 1 Negative Genetic
MRPL50 YNR022C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MCP1 YOR228C Mitochondrial protein of unknown function involved in lipid homeostas genetic 1 1 1 Negative Genetic
MCH4 YOL119C Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Negative Genetic
CPR8 YNR028W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
MIC10 YCL057C-A Conserved component of the MICOS complex physical 1 1 1 Affinity Capture-MS
EMC3 YKL207W Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Negative Genetic
AIM36 YMR157C Protein of unknown function genetic 1 1 1 Negative Genetic
HMI1 YOL095C Mitochondrial inner membrane localized ATP-dependent DNA helicase genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
OMA1 YKR087C Metalloendopeptidase of the mitochondrial inner membrane genetic 1 1 1 Phenotypic Suppression
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
IZH1 YDR492W Membrane protein involved in zinc ion homeostasis genetic 1 1 1 Negative Genetic
ASP3-3 YLR158C Cell-wall L-asparaginase II involved in asparagine catabolism genetic 1 1 1 Negative Genetic