Standard name Systematic name Name description Description
VMA6 YLR447C Subunit d of the V0 integral membrane domain of V-ATPase Subunit d of the V0 integral membrane domain of V-ATPase; part of the electrogenic proton pump found in the endomembrane system; required for V1 domain assembly on the vacuolar membrane; the V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase) has five subunits
Visualize the interactome of VMA6
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
vacuolar membrane 1630

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
VMA6 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1086 (V-ATPase, vacuole), r_1085 (V-ATPase, Golgi)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain physical 12 6 11 Affinity Capture-Western, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Co-purification
VMA21 YGR105W Integral membrane protein required for V-ATPase function physical 4 3 4 Affinity Capture-MS, Affinity Capture-Western, PCA, Affinity Capture-MS
VMA7 YGR020C Subunit F of the V1 peripheral membrane domain of V-ATPase physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA
VMA22 YHR060W Protein that is required for vacuolar H+-ATPase (V-ATPase) function physical 4 1 3 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase physical 3 3 3 Affinity Capture-Western, Reconstituted Complex, Co-purification
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase physical 2 2 2 PCA, Protein-peptide
VMA4 YOR332W Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) physical 2 2 2 Two-hybrid, Protein-peptide
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase physical 2 2 2 PCA, Protein-peptide
STV1 YMR054W Subunit a of the vacuolar-ATPase V0 domain physical 2 2 2 Affinity Capture-Western, Co-purification
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 2 1 1 Dosage Lethality, Dosage Lethality
SCH9 YHR205W AGC family protein kinase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-PCR evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-PCR evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Synthetic Growth Defect
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease physical 1 1 1 Affinity Capture-MS
LAS17 YOR181W Actin assembly factor physical 1 1 1 Affinity Capture-MS
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Synthetic Growth Defect
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Synthetic Growth Defect
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Synthetic Lethality
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
VMA10 YHR039C-A Subunit G of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Reconstituted Complex
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
VPH2 YKL119C Integral membrane protein required for V-ATPase function physical 1 1 1 Affinity Capture-MS
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor physical 1 1 1 Two-hybrid
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 PCA
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase physical 1 1 1 PCA
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE physical 1 1 1 Co-purification
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Synthetic Lethality
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) physical 1 1 1 Affinity Capture-MS
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
CNB1 YKL190W Calcineurin B genetic 1 1 1 Synthetic Lethality
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network physical 1 1 1 Affinity Capture-MS
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation physical 1 1 1 Two-hybrid
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) physical 1 1 1 Proximity Label-MS
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 1 1 1 Proximity Label-MS
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 1 1 1 Synthetic Rescue
OMS1 YDR316W Protein integral to the mitochondrial membrane physical 1 1 1 Affinity Capture-MS
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family physical 1 1 1 Two-hybrid
STD1 YOR047C Protein involved in control of glucose-regulated gene expression physical 1 1 1 Two-hybrid
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Synthetic Lethality
MTH1 YDR277C Negative regulator of the glucose-sensing signal transduction pathway physical 1 1 1 Two-hybrid
REV3 YPL167C Catalytic subunit of DNA polymerase zeta genetic 1 1 1 Synthetic Lethality
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Synthetic Growth Defect
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Positive Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Synthetic Growth Defect
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Synthetic Lethality
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
MYG1 YER156C Protein involved in mitochondrial function physical 1 1 1 Proximity Label-MS
MAY24 YPR153W Peripheral ER membrane protein genetic 1 1 1 Negative Genetic