STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
13 |
6 |
10 |
Dosage Rescue, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Lethality, Dosage Rescue, Negative Genetic, Synthetic Growth Defect, Synthetic Rescue, Negative Genetic, Negative Genetic |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
physical |
13 |
5 |
10 |
Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification |
VMA6 |
YLR447C |
Subunit d of the V0 integral membrane domain of V-ATPase |
physical |
12 |
6 |
11 |
Affinity Capture-Western, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Co-purification |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
physical |
10 |
7 |
9 |
Reconstituted Complex, Affinity Capture-Western, Co-fractionation, PCA, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, PCA, Protein-peptide, Co-crystal Structure |
VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
physical |
7 |
4 |
7 |
Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, FRET |
VMA7 |
YGR020C |
Subunit F of the V1 peripheral membrane domain of V-ATPase |
physical |
7 |
4 |
6 |
Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-Western |
VMA5 |
YKL080W |
Subunit C of the V1 peripheral membrane domain of V-ATPase |
physical |
6 |
5 |
6 |
Affinity Capture-Western, Co-fractionation, Affinity Capture-Western, Reconstituted Complex, Protein-peptide, FRET |
VMA4 |
YOR332W |
Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) |
physical |
5 |
3 |
5 |
Affinity Capture-Western, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Protein-peptide |
VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
physical |
5 |
3 |
5 |
Affinity Capture-Western, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Co-purification |
RAV1 |
YJR033C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
physical |
5 |
2 |
3 |
Two-hybrid, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Reconstituted Complex |
VMA10 |
YHR039C-A |
Subunit G of the V1 peripheral membrane domain of V-ATPase |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Protein-peptide, Co-crystal Structure |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Co-fractionation, PCA, Affinity Capture-Western |
VMA11 |
YPL234C |
Vacuolar ATPase V0 domain subunit c' |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Co-fractionation, Affinity Capture-Western, Co-purification |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-Western, PCA, Affinity Capture-Western |
FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
4 |
3 |
3 |
Positive Genetic, Positive Genetic, Synthetic Rescue, Phenotypic Suppression |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
4 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
3 |
3 |
3 |
Protein-peptide, Affinity Capture-Western, Reconstituted Complex |
VMA16 |
YHR026W |
Subunit c'' of the vacuolar ATPase |
physical |
3 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Co-purification |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
physical |
3 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Co-purification |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
genetic |
3 |
2 |
2 |
Positive Genetic, Synthetic Rescue, Synthetic Rescue |
GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Positive Genetic |
IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SKI3 |
YPR189W |
Ski complex component and TPR protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TSA2 |
YDR453C |
Stress inducible cytoplasmic thioredoxin peroxidase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
3 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
PRR1 |
YKL116C |
Serine/threonine protein kinase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
YPT10 |
YBR264C |
Rab family GTP-binding protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ZRC1 |
YMR243C |
Vacuolar membrane zinc transporter |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ERV46 |
YAL042W |
Protein localized to COPII-coated vesicles |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
EDS1 |
YBR033W |
Putative zinc cluster protein, predicted to be a transcription factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VHC1 |
YBR235W |
Vacuolar membrane cation-chloride cotransporter (CCC) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MYG1 |
YER156C |
Protein involved in mitochondrial function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RIM9 |
YMR063W |
Plasma membrane protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
PMC1 |
YGL006W |
Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions |
physical |
2 |
2 |
2 |
PCA, Affinity Capture-Western |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
2 |
1 |
2 |
DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence |
APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CNB1 |
YKL190W |
Calcineurin B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DOG1 |
YHR044C |
2-deoxyglucose-6-phosphate phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FIR1 |
YER032W |
Protein involved in 3' mRNA processing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GDA1 |
YEL042W |
Guanosine diphosphatase located in the Golgi |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FRE1 |
YLR214W |
Ferric reductase and cupric reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ALG9 |
YNL219C |
Mannosyltransferase, involved in N-linked glycosylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAU12 |
YGR294W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA6 |
YLR447C |
Subunit d of the V0 integral membrane domain of V-ATPase |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
DPB3 |
YBR278W |
Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
BIT2 |
YBR270C |
Subunit of TORC2 membrane-associated complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
OCA2 |
YNL056W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ELO3 |
YLR372W |
Elongase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
PCK1 |
YKR097W |
Phosphoenolpyruvate carboxykinase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
SET6 |
YPL165C |
SET domain protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MIC60 |
YKR016W |
Component of the MICOS complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ASH1 |
YKL185W |
Component of the Rpd3L histone deacetylase complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
MES1 |
YGR264C |
Methionyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIS3 |
YOL021C |
Exosome core complex catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP42 |
YDL111C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEX1 |
YOR112W |
Component of nuclear aminoacylation-dependent tRNA export pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PEP1 |
YBL017C |
Type I transmembrane sorting receptor for multiple vacuolar hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
ABD1 |
YBR236C |
Methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AOS1 |
YPR180W |
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
APL5 |
YPL195W |
Delta adaptin-like subunit of the clathrin associated protein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Positive Genetic |
CAF130 |
YGR134W |
Subunit of the CCR4-NOT transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIX1 |
YHR197W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CPR1 |
YDR155C |
Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENO1 |
YGR254W |
Enolase I, a phosphopyruvate hydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
FTH1 |
YBR207W |
Putative high affinity iron transporter |
physical |
1 |
1 |
1 |
PCA |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL19 |
YNL185C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRPL24 |
YMR193W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO80 |
YGL150C |
Nucleosome spacing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CWC22 |
YGR278W |
Spliceosome-associated protein that is required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDC1 |
YLR044C |
Major of three pyruvate decarboxylase isozymes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSI1 |
YMR025W |
Subunit of the Cop9 signalosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RSA4 |
YCR072C |
Ribosomal large subunit (60S) assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGI1 |
YBR196C |
Glycolytic enzyme phosphoglucose isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC25 |
YLR310C |
Membrane bound guanine nucleotide exchange factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKN1 |
YGR143W |
Protein involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
PCA |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
LYS9 |
YNR050C |
Saccharopine dehydrogenase (NADP+, L-glutamate-forming) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PYC2 |
YBR218C |
Pyruvate carboxylase isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRB1 |
YEL060C |
Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
RHO5 |
YNL180C |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP6 |
YDL213C |
rRNA-binding protein required for 40S ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESL2 |
YKR096W |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
PDI1 |
YCL043C |
Protein disulfide isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG11 |
YPR049C |
Adapter protein for pexophagy and the Cvt targeting pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG42 |
YBR139W |
Vacuolar serine-type carboxypeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AYR1 |
YIL124W |
Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DLD3 |
YEL071W |
2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DSK2 |
YMR276W |
Nuclear-enriched ubiquitin-like polyubiquitin-binding protein |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPN3 |
YLR243W |
Putative GTPase with a role in biogenesis of RNA pol II and polIII |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
1 |
1 |
1 |
Positive Genetic |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMI2 |
YDR516C |
Hexokinase expressed during growth with low glucose levels |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGM1 |
YKL127W |
Phosphoglucomutase, minor isoform |
genetic |
1 |
1 |
1 |
Positive Genetic |
THI21 |
YPL258C |
Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GBP2 |
YCL011C |
Poly(A+) RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
APE2 |
YKL157W |
Aminopeptidase yscII |
genetic |
1 |
1 |
1 |
Positive Genetic |
PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTQ2 |
YDR140W |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAL82 |
YNL314W |
Positive regulator of allophanate inducible genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
FIG1 |
YBR040W |
Integral membrane protein required for efficient mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
physical |
1 |
1 |
1 |
PCA |
MCM16 |
YPR046W |
Component of the Ctf19 complex and the COMA subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GNP1 |
YDR508C |
Broad specificity amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB2 |
YMR053C |
Protein that interacts with Sin3p in a two-hybrid assay |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA22 |
YHR060W |
Protein that is required for vacuolar H+-ATPase (V-ATPase) function |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAM6 |
YLR072W |
Sterol transporter that transfers sterols between membranes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAM35 |
YHR083W |
Component of the sorting and assembly machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX17 |
YNL214W |
Membrane peroxin of the peroxisomal importomer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWC7 |
YLR385C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG8 |
YBL078C |
Ub-like protein |
physical |
1 |
1 |
1 |
Co-localization |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VTC1 |
YER072W |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
VTC4 |
YJL012C |
Vacuolar membrane polyphosphate polymerase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDL157C |
YDL157C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT7 |
YML001W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YMD8 |
YML038C |
Putative nucleotide sugar transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
YGL114W |
YGL114W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YIR016W |
YIR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPT1 |
YFL038C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YEA4 |
YEL004W |
Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
YER152C |
YER152C |
Protein with 2-aminoadipate transaminase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS45 |
YGL095C |
Protein of the Sec1p/Munc-18 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCH1 |
YGR203W |
Phosphatase with sequence similarity to Mih1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR283C |
YGR283C |
Putative methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR045W |
YHR045W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKR015C |
YKR015C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
XYL2 |
YLR070C |
Xylitol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR179C |
YLR179C |
Protein of unknown function with similarity to Tfs1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS36 |
YLR417W |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML037C |
YML037C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR321C |
YMR321C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL194C |
YNL194C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL159C-A |
YOL159C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPF1 |
YKL100C |
Intramembrane aspartyl protease of the perinuclear ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CST9 |
YLR394W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
RSM19 |
YNR037C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
IVY1 |
YDR229W |
Phospholipid-binding protein that interacts with both Ypt7p and Vps33p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MGA1 |
YGR249W |
Protein similar to heat shock transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL1B |
YGL135W |
Ribosomal 60S subunit protein L1B |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCW4 |
YGR279C |
Cell wall protein with similarity to glucanases |
genetic |
1 |
1 |
1 |
Negative Genetic |
AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BSD2 |
YBR290W |
Heavy metal ion homeostasis protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
1 |
1 |
1 |
Negative Genetic |
STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
UBX7 |
YBR273C |
UBX (ubiquitin regulatory X) domain-containing protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF6 |
YJR082C |
Subunit of the NuA4 acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEU1 |
YLR017W |
Methylthioadenosine phosphorylase (MTAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTA1 |
YEL043W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARR3 |
YPR201W |
Plasma membrane metalloid/H+ antiporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSG1 |
YKL077W |
Protein that promotes the transport and maturation of Pma1 with Exp1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DIC1 |
YLR348C |
Mitochondrial dicarboxylate carrier |
genetic |
1 |
1 |
1 |
Negative Genetic |
LYS20 |
YDL182W |
Homocitrate synthase isozyme and functions in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NGR1 |
YBR212W |
RNA binding protein that negatively regulates growth rate |
genetic |
1 |
1 |
1 |
Negative Genetic |
NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ICL1 |
YER065C |
Isocitrate lyase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
UBP2 |
YOR124C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MVB12 |
YGR206W |
ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP1A |
YDL081C |
Ribosomal stalk protein P1 alpha |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMT1 |
YJL147C |
Translational repressor of the mitochondrial ATP6/8 mRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS25B |
YLR333C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAC14 |
YLR386W |
Enzyme regulator |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PGS1 |
YCL004W |
Phosphatidylglycerolphosphate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB2 |
YFL037W |
Beta-tubulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SND1 |
YDR186C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI17 |
YDR434W |
Transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPT1 |
YDR072C |
Inositolphosphotransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LOA1 |
YPR139C |
Lysophosphatidic acid acyltransferase |
physical |
1 |
1 |
1 |
Co-fractionation |
VCX1 |
YDL128W |
Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
FMP45 |
YDL222C |
Integral membrane protein localized to mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
AST2 |
YER101C |
Lipid raft associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
KIP3 |
YGL216W |
Kinesin-related antiparallel sliding motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG4 |
YGL012W |
C-24(28) sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
PMC1 |
YGL006W |
Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GOT1 |
YMR292W |
Homodimeric protein that is packaged into COPII vesicles |
genetic |
1 |
1 |
1 |
Positive Genetic |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
physical |
1 |
1 |
1 |
PCA |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARO7 |
YPR060C |
Chorismate mutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BSC4 |
YNL269W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHA2 |
YNL316C |
Prephenate dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VNX1 |
YNL321W |
Calcium/H+ antiporter localized to the endoplasmic reticulum membrane |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MYG1 |
YER156C |
Protein involved in mitochondrial function |
physical |
1 |
1 |
1 |
Proximity Label-MS |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
1 |
1 |
1 |
Negative Genetic |
TDA5 |
YLR426W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOG2 |
YHR043C |
2-deoxyglucose-6-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AFG1 |
YEL052W |
Protein that may act as a chaperone for cytochrome c oxidase subunits |
genetic |
1 |
1 |
1 |
Positive Genetic |
IRC20 |
YLR247C |
E3 ubiquitin ligase and putative helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
APS3 |
YJL024C |
Small subunit of the clathrin-associated adaptor complex AP-3 |
genetic |
1 |
1 |
1 |
Positive Genetic |
HXT9 |
YJL219W |
Putative hexose transporter that is nearly identical to Hxt11p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADY2 |
YCR010C |
Acetate transporter required for normal sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ALG8 |
YOR067C |
Glucosyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALK2 |
YBL009W |
Atypical protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRM7 |
YDL039C |
Pheromone-regulated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EFM3 |
YJR129C |
S-adenosylmethionine-dependent methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNT3 |
YIL014W |
Alpha-1,3-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM14 |
YHR132C |
Conserved fungal protein with similarity to zinc carboxypeptidases |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
RML2 |
YEL050C |
Mitochondrial ribosomal protein of the large subunit (L2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RSO55 |
YLR281C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMD9 |
YGL107C |
Mitochondrial protein that controls mitochondrial gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSC10 |
YBR265W |
3-ketosphinganine reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAU11 |
YGL261C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |