Standard name Systematic name Name description Description
PGI1 YBR196C Glycolytic enzyme phosphoglucose isomerase Glycolytic enzyme phosphoglucose isomerase; catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate; required for cell cycle progression and completion of the gluconeogenic events of sporulation
Visualize the interactome of PGI1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.996 1.0 0.993

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 91600

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PGI1 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0467 (glucose-6-phosphate isomerase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 3 2 3 Affinity Capture-RNA, Affinity Capture-MS, Affinity Capture-RNA
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 2 2 2 Biochemical Activity, Affinity Capture-MS
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PGI1 YBR196C Glycolytic enzyme phosphoglucose isomerase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT2 YER161C Protein involved in negative regulation of transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
MAK16 YAL025C Essential nuclear protein genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
MES1 YGR264C Methionyl-tRNA synthetase physical 1 1 1 Affinity Capture-RNA
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-RNA
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 1 1 1 Affinity Capture-MS
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Positive Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Affinity Capture-Western
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease physical 1 1 1 Affinity Capture-MS
ECM5 YMR176W Subunit of the Snt2C complex physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
EHD3 YDR036C 3-hydroxyisobutyryl-CoA hydrolase physical 1 1 1 Proximity Label-MS
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Negative Genetic
NHP6B YBR089C-A High-mobility group (HMG) protein genetic 1 1 1 Negative Genetic
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Phenotypic Enhancement
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Negative Genetic
SAW1 YAL027W 5'- and 3'-flap DNA binding protein physical 1 1 1 Affinity Capture-MS
SAP4 YGL229C Protein required for function of the Sit4p protein phosphatase physical 1 1 1 Two-hybrid
SUP35 YDR172W Translation termination factor eRF3 physical 1 1 1 Affinity Capture-MS
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain physical 1 1 1 Affinity Capture-MS
SPO12 YHR152W Nucleolar protein of unknown function physical 1 1 1 Affinity Capture-MS
SKP1 YDR328C Evolutionarily conserved kinetochore protein physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
RPL7A YGL076C Ribosomal 60S subunit protein L7A physical 1 1 1 Affinity Capture-MS
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RMP1 YLR145W Subunit of RNase MRP physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
SNQ2 YDR011W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation physical 1 1 1 Affinity Capture-MS
VID24 YBR105C GID Complex regulatory subunit physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
SME1 YOR159C Core Sm protein Sm E genetic 1 1 1 Negative Genetic
RPL13A YDL082W Ribosomal 60S subunit protein L13A genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
SKN1 YGR143W Protein involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
PMT3 YOR321W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
SKG6 YHR149C Integral membrane protein genetic 1 1 1 Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
ABF2 YMR072W Mitochondrial DNA-binding protein physical 1 1 1 Affinity Capture-MS
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III genetic 1 1 1 Positive Genetic
GAL3 YDR009W Transcriptional regulator genetic 1 1 1 Phenotypic Enhancement
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
CYS3 YAL012W Cystathionine gamma-lyase genetic 1 1 1 Negative Genetic
GDH2 YDL215C NAD(+)-dependent glutamate dehydrogenase genetic 1 1 1 Dosage Rescue
APL4 YPR029C Gamma-adaptin physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance physical 1 1 1 Affinity Capture-MS
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Negative Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 1 1 1 Affinity Capture-MS
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 1 1 1 Negative Genetic
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly genetic 1 1 1 Negative Genetic
ATP15 YPL271W Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
AIM22 YJL046W Lipoate-protein ligase genetic 1 1 1 Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Negative Genetic
GEP7 YGL057C Protein of unknown function genetic 1 1 1 Negative Genetic
ATG32 YIL146C Mitochondrial outer membrane protein required to initiate mitophagy genetic 1 1 1 Negative Genetic
CUL3 YGR003W Ubiquitin-protein ligase genetic 1 1 1 Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Negative Genetic
FLO11 YIR019C GPI-anchored cell surface glycoprotein (flocculin) genetic 1 1 1 Phenotypic Suppression
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
COA3 YJL062W-A Mitochondrial protein required for cytochrome c oxidase assembly physical 1 1 1 Affinity Capture-MS
GAA1 YLR088W Subunit of the GPI:protein transamidase complex physical 1 1 1 Affinity Capture-MS
HEM1 YDR232W 5-aminolevulinate synthase genetic 1 1 1 Negative Genetic
GIS1 YDR096W Histone demethylase and transcription factor physical 1 1 1 Affinity Capture-MS
MUP1 YGR055W High affinity methionine permease genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Negative Genetic
MYG1 YER156C Protein involved in mitochondrial function physical 1 1 1 Proximity Label-MS
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Negative Genetic
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic
NCA3 YJL116C Protein involved in mitochondrion organization genetic 1 1 1 Negative Genetic