Standard name Systematic name Name description Description
CTF8 YHR191C Subunit of a complex with Ctf18p Subunit of a complex with Ctf18p; shares some subunits with Replication Factor C; required for sister chromatid cohesion
Visualize the interactome of CTF8
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CTF8 1 10 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CHL1 YPL008W Probable DNA helicase genetic 13 6 9 Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Suppression
CSM3 YMR048W Replication fork associated factor genetic 13 4 8 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 12 4 9 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 11 3 9 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 11 3 9 Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 11 4 8 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Dosage Lethality, Negative Genetic, Negative Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 11 3 8 Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 11 3 6 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 10 3 8 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding genetic 10 3 8 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 10 2 8 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 10 3 7 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 10 3 6 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 9 2 8 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 9 2 7 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 9 1 7 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 9 3 6 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 9 2 6 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SLK19 YOR195W Kinetochore-associated protein genetic 8 2 7 Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 8 4 6 Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Positive Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 8 2 6 Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
DDC1 YPL194W DNA damage checkpoint protein genetic 8 2 6 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 8 1 6 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 7 2 7 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 7 3 6 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 7 3 6 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 7 3 6 Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 7 3 6 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 7 2 6 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
HTA1 YDR225W Histone H2A genetic 7 2 6 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
VIK1 YPL253C Protein that forms a kinesin-14 heterodimeric motor with Kar3p genetic 7 2 6 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RAD17 YOR368W Checkpoint protein genetic 7 2 6 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 7 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p physical 6 3 6 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
CIN8 YEL061C Bipolar kinesin motor protein genetic 6 2 6 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 6 2 5 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 6 2 5 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 6 2 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 6 2 5 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 6 2 5 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 6 2 5 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 6 2 5 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD61 YDR014W Subunit of a complex that inhibits sister chromatid cohesion genetic 6 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 6 2 4 Positive Genetic, Positive Genetic, Positive Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 6 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 5 2 5 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 5 3 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 5 3 4 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 5 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 5 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 5 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 5 2 4 Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein genetic 5 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 5 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 5 2 4 Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 5 1 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
SAC3 YDR159W mRNA export factor genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 5 3 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 5 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 5 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
SWI6 YLR182W Transcription cofactor genetic 4 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 4 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 4 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CDC45 YLR103C DNA replication initiation factor genetic 4 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
ECO1 YFR027W Acetyltransferase required for sister chromatid cohesion genetic 4 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 4 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 4 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RAD24 YER173W Checkpoint protein genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 4 2 3 Positive Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 4 3 2 Synthetic Growth Defect, Positive Genetic, Positive Genetic, Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 4 2 2 Positive Genetic, Negative Genetic, Positive Genetic, Negative Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 3 3 3 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
LSM1 YJL124C Lsm (Like Sm) protein genetic 3 3 3 Synthetic Growth Defect, Negative Genetic, Positive Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
CDC26 YFR036W Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 3 1 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
HUR1 YGL168W Protein with a role in DNA repair genetic 3 1 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 3 1 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
TUB3 YML124C Alpha-tubulin genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 3 2 2 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 3 2 2 Negative Genetic, Negative Genetic, Synthetic Growth Defect
RAD51 YER095W Strand exchange protein genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
APC9 YLR102C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PDS1 YDR113C Securin genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SSF2 YDR312W Protein required for ribosomal large subunit maturation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
SET6 YPL165C SET domain protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
RAD55 YDR076W Protein that stimulates strand exchange genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CMD1 YBR109C Calmodulin genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 2 2 2 Negative Genetic, Positive Genetic
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 2 2 Synthetic Lethality, Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 2 2 2 Synthetic Lethality, Negative Genetic
MCM2 YBL023C Protein involved in DNA replication genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
SGO1 YOR073W Component of the spindle checkpoint genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
LSM7 YNL147W Lsm (Like Sm) protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 2 2 2 Phenotypic Suppression, Negative Genetic
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder genetic 2 2 2 Phenotypic Suppression, Dosage Growth Defect
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
TOP3 YLR234W DNA Topoisomerase III genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SNF8 YPL002C Component of the ESCRT-II complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
VPS3 YDR495C Component of CORVET membrane tethering complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
VPS45 YGL095C Protein of the Sec1p/Munc-18 family genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
MDM20 YOL076W Non-catalytic subunit of the NatB N-terminal acetyltransferase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 2 1 2 Negative Genetic, Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 2 Negative Genetic, Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Positive Genetic, Positive Genetic
BUB2 YMR055C Mitotic exit network regulator genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 2 1 2 Negative Genetic, Negative Genetic
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 2 Negative Genetic, Negative Genetic
APN1 YKL114C Major apurinic/apyrimidinic endonuclease genetic 2 1 2 Negative Genetic, Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 2 1 2 Negative Genetic, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 2 1 2 Negative Genetic, Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 2 1 2 Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 2 1 2 Negative Genetic, Negative Genetic
DPB4 YDR121W Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
PAC2 YER007W Microtubule effector required for tubulin heterodimer formation genetic 2 1 2 Negative Genetic, Negative Genetic
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 2 1 2 Negative Genetic, Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 2 1 2 Positive Genetic, Positive Genetic
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 2 1 2 Positive Genetic, Positive Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 2 1 2 Positive Genetic, Positive Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 2 Negative Genetic, Negative Genetic
RBK1 YCR036W Ribokinase, phosphorylates ribose to ribose-5-phosphate genetic 2 1 2 Negative Genetic, Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 2 1 2 Negative Genetic, Negative Genetic
YIL161W YIL161W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
TAX4 YJL083W EH domain-containing protein genetic 2 1 2 Negative Genetic, Negative Genetic
PAM17 YKR065C Constituent of the TIM23 complex genetic 2 1 2 Negative Genetic, Negative Genetic
RCF2 YNR018W Cytochrome c oxidase subunit genetic 2 1 2 Negative Genetic, Negative Genetic
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
YOL014W YOL014W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
MSN5 YDR335W Karyopherin genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SPT2 YER161C Protein involved in negative regulation of transcription genetic 2 1 2 Negative Genetic, Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 2 1 2 Positive Genetic, Positive Genetic
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 2 1 2 Negative Genetic, Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 2 1 2 Negative Genetic, Negative Genetic
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 2 1 2 Negative Genetic, Negative Genetic
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 2 Negative Genetic, Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 2 1 2 Negative Genetic, Negative Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 2 1 2 Negative Genetic, Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 2 1 2 Negative Genetic, Negative Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 2 1 2 Negative Genetic, Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 2 1 2 Negative Genetic, Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 2 1 2 Positive Genetic, Positive Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 2 2 1 Positive Genetic, Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 2 1 1 Negative Genetic, Negative Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ASF1 YJL115W Nucleosome assembly factor genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 2 1 1 Negative Genetic, Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 2 1 1 Negative Genetic, Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 2 1 1 Negative Genetic, Negative Genetic
CDC16 YKL022C Subunit of the anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HHT1 YBR010W Histone H3 genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LCB4 YOR171C Sphingoid long-chain base kinase genetic 2 1 1 Negative Genetic, Negative Genetic
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD18 YCR066W E3 ubiquitin ligase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MPS3 YJL019W Nuclear envelope protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 2 1 1 Positive Genetic, Positive Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 2 1 1 Negative Genetic, Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 2 1 1 Negative Genetic, Negative Genetic
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 2 1 1 Negative Genetic, Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 2 1 1 Negative Genetic, Negative Genetic
SLD5 YDR489W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 2 1 1 Negative Genetic, Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 2 1 1 Negative Genetic, Negative Genetic
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
NBP35 YGL091C Essential cytoplasmic iron-sulfur cluster binding protein genetic 2 1 1 Negative Genetic, Negative Genetic
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 2 1 1 Negative Genetic, Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 1 Negative Genetic, Negative Genetic
PSF2 YJL072C Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 2 1 1 Negative Genetic, Negative Genetic
PRI2 YKL045W Subunit of DNA primase genetic 2 1 1 Negative Genetic, Negative Genetic
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex genetic 2 1 1 Negative Genetic, Negative Genetic
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex genetic 2 1 1 Negative Genetic, Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 2 1 1 Negative Genetic, Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 2 1 1 Negative Genetic, Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 2 1 1 Negative Genetic, Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
BRX1 YOL077C Nucleolar protein genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Growth Defect
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex genetic 1 1 1 Positive Genetic
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme genetic 1 1 1 Negative Genetic
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 1 1 1 Negative Genetic
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 1 1 1 Positive Genetic
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 1 1 1 Positive Genetic
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Synthetic Growth Defect
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Synthetic Growth Defect
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Positive Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 1 1 1 Negative Genetic
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor genetic 1 1 1 Negative Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Positive Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Synthetic Growth Defect
AKL1 YBR059C Ser/Thr protein kinase genetic 1 1 1 Positive Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism genetic 1 1 1 Synthetic Growth Defect
BOL2 YGL220W Cytosolic protein involved in repression of iron regulon transcription genetic 1 1 1 Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 1 1 1 Positive Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Negative Genetic
CIA1 YDR267C Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Positive Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes genetic 1 1 1 Synthetic Growth Defect
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-Western
RFC3 YNL290W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-Western
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-Western
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-Western
DPB2 YPR175W Second largest subunit of DNA polymerase II (DNA polymerase epsilon) physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
IRC3 YDR332W Double-stranded DNA-dependent helicase of the DExH/D-box family genetic 1 1 1 Synthetic Lethality
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Synthetic Lethality
MAM1 YER106W Monopolin genetic 1 1 1 Phenotypic Suppression
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Synthetic Lethality
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Synthetic Lethality
ORC5 YNL261W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Synthetic Lethality
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Synthetic Growth Defect
NPL6 YMR091C Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
RTT106 YNL206C Histone chaperone genetic 1 1 1 Negative Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 1 1 1 Negative Genetic
RAI1 YGL246C Nuclear decapping endonuclease genetic 1 1 1 Negative Genetic
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Negative Genetic
THP1 YOL072W Nuclear pore-associated protein genetic 1 1 1 Negative Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
RMI1 YPL024W Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex genetic 1 1 1 Negative Genetic
YUH1 YJR099W Ubiquitin C-terminal hydrolase genetic 1 1 1 Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Positive Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Positive Genetic
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex genetic 1 1 1 Positive Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Positive Genetic
ENV11 YGR071C Protein proposed to be involved in vacuolar functions genetic 1 1 1 Positive Genetic
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Positive Genetic
UBC5 YDR059C Ubiquitin-conjugating enzyme genetic 1 1 1 Positive Genetic
YCH1 YGR203W Phosphatase with sequence similarity to Mih1p genetic 1 1 1 Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Positive Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Positive Genetic
SPT6 YGR116W Nucleosome remodeling protein genetic 1 1 1 Positive Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 1 1 1 Synthetic Growth Defect
UBC13 YDR092W E2 ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
HSP31 YDR533C Methylglyoxalase that converts methylglyoxal to D-lactate genetic 1 1 1 Negative Genetic
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation genetic 1 1 1 Negative Genetic
HAP4 YKL109W Transcription factor genetic 1 1 1 Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 1 1 1 Negative Genetic
RFM1 YOR279C Component of the Sum1p-Rfm1p-Hst1p complex genetic 1 1 1 Negative Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Synthetic Growth Defect
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Synthetic Growth Defect
HIT1 YJR055W Protein involved in C/D snoRNP assembly genetic 1 1 1 Synthetic Growth Defect
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Synthetic Growth Defect
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Synthetic Growth Defect
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Synthetic Growth Defect
PEP5 YMR231W Histone E3 ligase, component of CORVET membrane tethering complex genetic 1 1 1 Synthetic Growth Defect
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Synthetic Growth Defect
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Synthetic Growth Defect
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Synthetic Growth Defect
UBP14 YBR058C Ubiquitin-specific protease genetic 1 1 1 Synthetic Growth Defect
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Synthetic Growth Defect
VPS16 YPL045W Subunit of the HOPS and the CORVET complexes genetic 1 1 1 Synthetic Growth Defect
VPS25 YJR102C Component of the ESCRT-II complex genetic 1 1 1 Synthetic Growth Defect
VPS33 YLR396C ATP-binding protein that is a subunit of the HOPS and CORVET complexes genetic 1 1 1 Synthetic Growth Defect
VPS36 YLR417W Component of the ESCRT-II complex genetic 1 1 1 Synthetic Growth Defect
IRC15 YPL017C Microtubule associated protein genetic 1 1 1 Synthetic Growth Defect
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Synthetic Growth Defect
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Synthetic Growth Defect
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Synthetic Growth Defect
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate genetic 1 1 1 Synthetic Growth Defect
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit genetic 1 1 1 Synthetic Lethality
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Synthetic Growth Defect
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 1 1 1 Synthetic Rescue
HST4 YDR191W NAD(+)-dependent protein deacetylase genetic 1 1 1 Synthetic Rescue
GAL80 YML051W Transcriptional regulator involved in the repression of GAL genes genetic 1 1 1 Positive Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 1 1 1 Negative Genetic
ZAP1 YJL056C Zinc-regulated transcription factor genetic 1 1 1 Positive Genetic
RDS2 YPL133C Transcription factor involved in regulating gluconeogenesis genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Negative Genetic
HHT2 YNL031C Histone H3 genetic 1 1 1 Negative Genetic
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Synthetic Growth Defect
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Positive Genetic
YVH1 YIR026C Dual specificity protein phosphatase genetic 1 1 1 Positive Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes genetic 1 1 1 Negative Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Negative Genetic
YRR1 YOR162C Zn2-Cys6 zinc-finger transcription factor genetic 1 1 1 Positive Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Negative Genetic
DMA2 YNL116W Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
MDS3 YGL197W Putative component of the TOR regulatory pathway genetic 1 1 1 Negative Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Synthetic Growth Defect
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
LSM2 YBL026W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Positive Genetic
NUS1 YDL193W Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 genetic 1 1 1 Positive Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Positive Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Positive Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Positive Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Positive Genetic
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase genetic 1 1 1 Positive Genetic
TFC1 YBR123C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Positive Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Positive Genetic
SEC53 YFL045C Phosphomannomutase genetic 1 1 1 Positive Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 1 1 1 Positive Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Positive Genetic
GPI1 YGR216C Membrane protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Positive Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Positive Genetic
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Positive Genetic
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Positive Genetic
RRN7 YJL025W Component of the core factor (CF) rDNA transcription factor complex genetic 1 1 1 Positive Genetic
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Positive Genetic
GAA1 YLR088W Subunit of the GPI:protein transamidase complex genetic 1 1 1 Positive Genetic
SEC10 YLR166C Essential 100kDa subunit of the exocyst complex genetic 1 1 1 Positive Genetic
SMC6 YLR383W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase genetic 1 1 1 Positive Genetic
LIP1 YMR298W Ceramide synthase subunit genetic 1 1 1 Positive Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Positive Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Positive Genetic
VPS68 YOL129W Vacuolar membrane protein of unknown function genetic 1 1 1 Positive Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Positive Genetic
SEC17 YBL050W Alpha-SNAP cochaperone genetic 1 1 1 Negative Genetic
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Negative Genetic
RIB5 YBR256C Riboflavin synthase genetic 1 1 1 Negative Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SCM3 YDL139C Nonhistone component of centromeric chromatin genetic 1 1 1 Negative Genetic
UBC1 YDR177W Ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Negative Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
PRE1 YER012W Beta 4 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Negative Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Negative Genetic
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
SPC42 YKL042W Central plaque component of spindle pole body (SPB) genetic 1 1 1 Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
TAF11 YML015C TFIID subunit (40 kDa) genetic 1 1 1 Negative Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 1 1 1 Negative Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Negative Genetic
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Negative Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Negative Genetic
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
HRP1 YOL123W Subunit of cleavage factor I genetic 1 1 1 Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
PUP1 YOR157C Beta 2 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 1 1 1 Negative Genetic
SPC29 YPL124W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 1 1 1 Negative Genetic
TAH18 YPR048W Conserved NAPDH-dependent diflavin reductase genetic 1 1 1 Negative Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
UTR5 YEL035C Protein of unknown function genetic 1 1 1 Negative Genetic
MCM6 YGL201C Protein involved in DNA replication genetic 1 1 1 Negative Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
RFA3 YJL173C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
DHR2 YKL078W Predominantly nucleolar DEAH-box ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
RSC4 YKR008W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Negative Genetic
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis genetic 1 1 1 Negative Genetic
MTR10 YOR160W Nuclear import receptor genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Negative Genetic
FUN19 YAL034C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
KIN3 YAR018C Nonessential serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex genetic 1 1 1 Negative Genetic
HSL7 YBR133C Protein arginine N-methyltransferase genetic 1 1 1 Negative Genetic
YBR221W-A YBR221W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YCR007C YCR007C Putative integral membrane protein genetic 1 1 1 Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Negative Genetic
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 1 1 1 Negative Genetic
RPL12B YDR418W Ribosomal 60S subunit protein L12B genetic 1 1 1 Negative Genetic
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Negative Genetic
UBC6 YER100W Ubiquitin-conjugating enzyme involved in ERAD genetic 1 1 1 Negative Genetic
SWP82 YFL049W Member of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
GTF1 YGR102C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
YGR122W YGR122W Protein that may be involved in pH regulation genetic 1 1 1 Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
GPC1 YGR149W Glycerophosphocholine acyltransferase (GPCAT) genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
PGI1 YBR196C Glycolytic enzyme phosphoglucose isomerase genetic 1 1 1 Negative Genetic
FAD1 YDL045C Flavin adenine dinucleotide (FAD) synthetase genetic 1 1 1 Negative Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 1 1 1 Negative Genetic
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Negative Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Negative Genetic
EMG1 YLR186W Methyltransferase for rRNA genetic 1 1 1 Negative Genetic
ORC1 YML065W Largest subunit of the origin recognition complex genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Negative Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
YJL136W-A YJL136W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
MNR2 YKL064W Vacuolar membrane protein required for magnesium homeostasis genetic 1 1 1 Negative Genetic
LMO1 YLL007C Homolog of mammalian ELMO (Engulfment and celL MOtility) genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 1 1 1 Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
YLR154C-H YLR154C-H Putative protein of unknown function genetic 1 1 1 Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
RPS1A YLR441C Ribosomal protein of the small (40S) subunit genetic 1 1 1 Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 1 1 1 Negative Genetic
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Negative Genetic
MTG1 YMR097C Putative GTPase peripheral to the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
GCV2 YMR189W P subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
GAS3 YMR215W Putative 1,3-beta-glucanosyltransferase genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
MPD2 YOL088C Member of the protein disulfide isomerase (PDI) family genetic 1 1 1 Negative Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Negative Genetic
YOR072W-B YOR072W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Negative Genetic
REF2 YDR195W RNA-binding protein genetic 1 1 1 Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Negative Genetic
YER134C YER134C Magnesium-dependent acid phosphatase genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Negative Genetic
YGL188C-A YGL188C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPS26A YGL189C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
DOC1 YGL240W Processivity factor genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 1 1 1 Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SDH4 YDR178W Membrane anchor subunit of succinate dehydrogenase (SDH) genetic 1 1 1 Negative Genetic
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 1 1 1 Negative Genetic
FIT1 YDR534C Mannoprotein that is incorporated into the cell wall genetic 1 1 1 Negative Genetic
IRC4 YDR540C Protein similar to bacterial secreted DfsB proteins genetic 1 1 1 Negative Genetic
PAN2 YGL094C Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex genetic 1 1 1 Negative Genetic
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 1 1 1 Negative Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
XYL2 YLR070C Xylitol dehydrogenase genetic 1 1 1 Negative Genetic
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Negative Genetic
MRPL39 YML009C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
HOS1 YPR068C Class I histone deacetylase (HDAC) family member genetic 1 1 1 Negative Genetic
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 1 1 1 Negative Genetic
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs genetic 1 1 1 Negative Genetic
SML1 YML058W Ribonucleotide reductase inhibitor genetic 1 1 1 Negative Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
YMR155W YMR155W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
PIN2 YOR104W Exomer-dependent cargo protein genetic 1 1 1 Negative Genetic
YOR376W-A YOR376W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Phenotypic Enhancement
DEF1 YKL054C RNAPII degradation factor genetic 1 1 1 Negative Genetic
PTP3 YER075C Phosphotyrosine-specific protein phosphatase genetic 1 1 1 Positive Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Positive Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 1 1 1 Positive Genetic
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Negative Genetic
MVP1 YMR004W Protein required for sorting proteins to the vacuole genetic 1 1 1 Negative Genetic
MRL1 YPR079W Membrane protein genetic 1 1 1 Negative Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Negative Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Negative Genetic
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Negative Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Negative Genetic
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Negative Genetic
ERV29 YGR284C Protein localized to COPII-coated vesicles genetic 1 1 1 Negative Genetic
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Negative Genetic
CNM67 YNL225C Component of the spindle pole body outer plaque genetic 1 1 1 Synthetic Growth Defect
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
BNR1 YIL159W Formin genetic 1 1 1 Negative Genetic
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Positive Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Negative Genetic
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
ALG1 YBR110W Mannosyltransferase genetic 1 1 1 Negative Genetic
ADE16 YLR028C Enzyme of 'de novo' purine biosynthesis genetic 1 1 1 Negative Genetic
ATG33 YLR356W Mitochondrial mitophagy-specific protein genetic 1 1 1 Negative Genetic
ALG13 YGL047W Catalytic component of UDP-GlcNAc transferase genetic 1 1 1 Positive Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 1 1 1 Positive Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
ALG2 YGL065C Mannosyltransferase in the N-linked glycosylation pathway genetic 1 1 1 Negative Genetic
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum genetic 1 1 1 Negative Genetic