Standard name Systematic name Name description Description
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase Cytoplasmic and mitochondrial glycyl-tRNA synthase; ligates glycine to the cognate anticodon-bearing tRNA; transcription termination factor that may interact with the 3'-end of pre-mRNA to promote 3'-end formation; GRS1 has a paralog, GRS2, that arose from the whole genome duplication; human homolog GARS implicated in Charcot-Marie-Tooth disease, can complement yeast null mutant
Visualize the interactome of GRS1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.991 0.992 0.982

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 98400

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
GRS1 3 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0512 (glycyl-tRNA synthetase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 2 2 Synthetic Haploinsufficiency, Positive Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
CHS1 YNL192W Chitin synthase I genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
RRP6 YOR001W Nuclear exosome exonuclease component physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 2 1 2 Negative Genetic, Negative Genetic
CHS5 YLR330W Component of the exomer complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
HRT3 YLR097C Putative SCF-ubiquitin ligase F-box protein physical 2 2 1 Two-hybrid, Affinity Capture-Western
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
KGD2 YDR148C Dihydrolipoyl transsuccinylase genetic 2 1 1 Negative Genetic, Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 2 1 1 Negative Genetic, Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
CYC8 YBR112C General transcriptional co-repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Positive Genetic
EMW1 YNL313C Essential conserved protein with a role in cell wall integrity physical 1 1 1 Affinity Capture-MS
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
CCL1 YPR025C Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p genetic 1 1 1 Negative Genetic
ATP11 YNL315C Molecular chaperone genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Negative Genetic
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome genetic 1 1 1 Positive Genetic
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 1 1 1 Negative Genetic
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) genetic 1 1 1 Positive Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Positive Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Positive Genetic
SUI1 YNL244C Translation initiation factor eIF1 physical 1 1 1 Affinity Capture-MS
MAG2 YLR427W Cytoplasmic protein of unknown function physical 1 1 1 Affinity Capture-MS
PRP6 YBR055C Splicing factor physical 1 1 1 Affinity Capture-MS
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 1 1 1 Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 1 1 1 Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex physical 1 1 1 Affinity Capture-MS
LAS1 YKR063C Endonuclease involved in pre-rRNA processing at both ends of ITS2 physical 1 1 1 Affinity Capture-MS
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 PCA
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 PCA
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
IRA2 YOL081W GTPase-activating protein physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
MYG1 YER156C Protein involved in mitochondrial function physical 1 1 1 Proximity Label-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Positive Genetic
HST2 YPL015C Cytoplasmic NAD(+)-dependent protein deacetylase genetic 1 1 1 Synthetic Growth Defect
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Negative Genetic
SDH1 YKL148C Flavoprotein subunit of succinate dehydrogenase genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
GRS2 YPR081C Glycine-tRNA synthetase, not expressed under normal growth conditions genetic 1 1 1 Dosage Rescue
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Positive Genetic
NAS2 YIL007C Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 1 1 1 Positive Genetic
RPS1B YML063W Ribosomal protein of the small (40S) subunit genetic 1 1 1 Positive Genetic
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Positive Genetic
PMS1 YNL082W ATP-binding protein required for mismatch repair genetic 1 1 1 Positive Genetic
MAY24 YPR153W Peripheral ER membrane protein genetic 1 1 1 Positive Genetic
REF2 YDR195W RNA-binding protein genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 1 1 1 Negative Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
URA6 YKL024C Uridylate kinase genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
RPC11 YDR045C RNA polymerase III subunit C11 genetic 1 1 1 Negative Genetic
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Negative Genetic
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
RBA50 YDR527W Protein involved in transcription genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
RPC82 YPR190C RNA polymerase III subunit C82 genetic 1 1 1 Negative Genetic
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
RPL13A YDL082W Ribosomal 60S subunit protein L13A genetic 1 1 1 Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
IOC3 YFR013W Subunit of the Isw1a complex genetic 1 1 1 Negative Genetic
RPL24A YGL031C Ribosomal 60S subunit protein L24A genetic 1 1 1 Negative Genetic
RME1 YGR044C Zinc finger protein involved in control of meiosis genetic 1 1 1 Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease genetic 1 1 1 Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
NCA3 YJL116C Protein involved in mitochondrion organization genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Negative Genetic
LOS1 YKL205W Nuclear pore protein genetic 1 1 1 Negative Genetic
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
RPS18B YML026C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
OCA1 YNL099C Putative protein tyrosine phosphatase genetic 1 1 1 Negative Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Negative Genetic
SPS4 YOR313C Protein whose expression is induced during sporulation genetic 1 1 1 Negative Genetic
YBR072C-A YBR072C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YDR061W YDR061W Protein with similarity to ABC transporter family members genetic 1 1 1 Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
YPQ2 YDR352W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Negative Genetic
RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
MIT1 YEL007W Transcriptional regulator of pseudohyphal growth genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
IGD1 YFR017C Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity genetic 1 1 1 Negative Genetic
PES4 YFR023W Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation genetic 1 1 1 Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Negative Genetic
RIF2 YLR453C Protein that binds to the Rap1p C-terminus genetic 1 1 1 Negative Genetic
LDS2 YOL047C Protein Involved in spore wall assembly genetic 1 1 1 Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Synthetic Growth Defect
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Positive Genetic
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family genetic 1 1 1 Positive Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 1 1 1 Synthetic Lethality
AIM18 YHR198C Protein of unknown function genetic 1 1 1 Positive Genetic
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Synthetic Lethality
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Positive Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Lethality
CQD1 YPL109C UbiB family mitochondrial protein genetic 1 1 1 Positive Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 1 1 1 Positive Genetic
BAP3 YDR046C Amino acid permease genetic 1 1 1 Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Positive Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
ALD6 YPL061W Cytosolic aldehyde dehydrogenase genetic 1 1 1 Positive Genetic
ATP12 YJL180C Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Negative Genetic
ATG33 YLR356W Mitochondrial mitophagy-specific protein genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b genetic 1 1 1 Negative Genetic
AIM11 YER093C-A Protein of unknown function genetic 1 1 1 Positive Genetic
ARO7 YPR060C Chorismate mutase genetic 1 1 1 Negative Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 1 1 1 Positive Genetic
ECM32 YER176W DNA dependent ATPase/DNA helicase genetic 1 1 1 Positive Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic