Standard name Systematic name Name description Description
SSF2 YDR312W Protein required for ribosomal large subunit maturation Protein required for ribosomal large subunit maturation; functionally redundant with Ssf1p; member of the Brix family; SSF2 has a paralog, SSF1, that arose from the whole genome duplication
Visualize the interactome of SSF2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.168 0.110 0.078
Nucleolus 0.548 0.548 0.756
Nucleus 0.434 0.370 0.160
Endosome NaN NaN 0.081
SpindlePole NaN NaN 0.192

GFP localization & abundance

GFP localization GFP abundance
nucleolus, nucleus 1350

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SSF2 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 6 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RRP15 YPR143W Nucleolar protein physical 4 2 2 Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
COX5A YNL052W Subunit Va of cytochrome c oxidase genetic 2 1 2 Negative Genetic, Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
ELO3 YLR372W Elongase genetic 2 1 2 Negative Genetic, Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
SIT1 YEL065W Ferrioxamine B transporter genetic 2 1 2 Negative Genetic, Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 2 1 2 Negative Genetic, Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 2 2 1 Positive Genetic, Negative Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BRX1 YOL077C Nucleolar protein genetic 1 1 1 Negative Genetic
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly physical 1 1 1 Two-hybrid
NSA1 YGL111W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit physical 1 1 1 Co-purification
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
SSF1 YHR066W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
PRP43 YGL120C RNA helicase in the DEAH-box family physical 1 1 1 Affinity Capture-MS
NOP15 YNL110C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
CIC1 YHR052W Essential protein that interacts with proteasome components physical 1 1 1 Affinity Capture-MS
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Synthetic Lethality
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Positive Genetic
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Dosage Rescue
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC genetic 1 1 1 Negative Genetic
NOC4 YPR144C Nucleolar protein physical 1 1 1 Affinity Capture-MS
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Biochemical Activity
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Positive Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
AKL1 YBR059C Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein physical 1 1 1 Affinity Capture-MS
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) physical 1 1 1 Biochemical Activity
NOP53 YPL146C Nucleolar protein physical 1 1 1 Two-hybrid
AIR1 YIL079C Zinc knuckle protein genetic 1 1 1 Synthetic Lethality
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases physical 1 1 1 Affinity Capture-Western
SIR1 YKR101W Protein involved in silencing at mating-type loci HML and HMR genetic 1 1 1 Dosage Rescue
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
FAR3 YMR052W Protein of unknown function genetic 1 1 1 Negative Genetic
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Negative Genetic
RPL20B YOR312C Ribosomal 60S subunit protein L20B genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Positive Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
DYS1 YHR068W Deoxyhypusine synthase genetic 1 1 1 Negative Genetic
PTR3 YFR029W Component of the SPS plasma membrane amino acid sensor system genetic 1 1 1 Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 1 1 1 Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Negative Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Positive Genetic
SPB4 YFL002C Putative ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
RTR1 YER139C Dual specificity protein phosphatase genetic 1 1 1 Negative Genetic
RSA3 YLR221C Protein with a likely role in ribosomal maturation genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Biochemical Activity
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein genetic 1 1 1 Negative Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
STE4 YOR212W G protein beta subunit genetic 1 1 1 Phenotypic Suppression
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Positive Genetic
TFB2 YPL122C Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
YBL055C YBL055C 3'-->5' exonuclease and endonuclease with a possible role in apoptosis genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
YLL006W-A YLL006W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
ATG15 YCR068W Phospholipase genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Negative Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Negative Genetic
HMI1 YOL095C Mitochondrial inner membrane localized ATP-dependent DNA helicase genetic 1 1 1 Positive Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
MSC6 YOR354C Multicopy suppressor of HER2 involved in mitochondrial translation genetic 1 1 1 Negative Genetic