Standard name Systematic name Name description Description
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S4, no bacterial homolog; RPS4B has a paralog, RPS4A, that arose from the whole genome duplication
Visualize the interactome of RPS4B
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 1.0 1.0 0.993

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 102000

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RPS4B 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 3 2 3 Affinity Capture-RNA, Affinity Capture-MS, Affinity Capture-RNA
GCN2 YDR283C Protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SOL2 YCR073W-A Protein with a possible role in tRNA export genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
THI74 YDR438W Mitochondrial transporter repressible by thiamine genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UBX6 YJL048C UBX (ubiquitin regulatory X) domain-containing protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TYW1 YPL207W Iron-sulfur protein required for synthesis of wybutosine modified tRNA genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
HBS1 YKR084C GTPase with similarity to translation release factors genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence
PAB1 YER165W Poly(A) binding protein physical 2 2 2 Co-fractionation, Co-purification
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 2 2 2 Synthetic Lethality, Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 2 2 Affinity Capture-RNA, Affinity Capture-MS
NOC4 YPR144C Nucleolar protein physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
LTV1 YKL143W Subunit of the EGO/GSE complex physical 2 2 2 Co-purification, Affinity Capture-MS
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class genetic 2 1 2 Negative Genetic, Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 2 1 2 Negative Genetic, Negative Genetic
TPC1 YGR096W Mitochondrial membrane transporter genetic 2 1 2 Negative Genetic, Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 2 1 2 Negative Genetic, Negative Genetic
TEX1 YNL253W Protein involved in mRNA export genetic 2 1 2 Negative Genetic, Negative Genetic
UBA3 YPR066W Protein that activates Rub1p (NEDD8) before neddylation genetic 2 1 2 Negative Genetic, Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 1 2 Negative Genetic, Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 2 1 2 Negative Genetic, Negative Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
EMP24 YGL200C Component of the p24 complex genetic 2 1 2 Negative Genetic, Negative Genetic
KIN3 YAR018C Nonessential serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 2 Positive Genetic, Positive Genetic
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
BUD32 YGR262C Protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
GAL7 YBR018C Galactose-1-phosphate uridyl transferase genetic 2 1 2 Negative Genetic, Negative Genetic
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p genetic 2 1 2 Positive Genetic, Positive Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 2 1 2 Negative Genetic, Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 2 1 2 Positive Genetic, Positive Genetic
MSN2 YMR037C Stress-responsive transcriptional activator genetic 2 1 2 Negative Genetic, Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 2 1 2 Negative Genetic, Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 2 1 2 Negative Genetic, Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 2 1 2 Negative Genetic, Negative Genetic
MFA2 YNL145W Mating pheromone a-factor genetic 2 1 2 Negative Genetic, Negative Genetic
BNS1 YGR230W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 2 1 2 Negative Genetic, Negative Genetic
ALD4 YOR374W Mitochondrial aldehyde dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
CUP9 YPL177C Homeodomain-containing transcriptional repressor genetic 2 1 2 Negative Genetic, Negative Genetic
RPS18B YML026C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Positive Genetic, Positive Genetic
LSC2 YGR244C Beta subunit of succinyl-CoA ligase genetic 2 1 2 Negative Genetic, Negative Genetic
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 2 1 2 Negative Genetic, Negative Genetic
LIP2 YLR239C Lipoyl ligase genetic 2 1 2 Negative Genetic, Negative Genetic
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 2 1 2 Negative Genetic, Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 2 1 1 Negative Genetic, Negative Genetic
UBI4 YLL039C Ubiquitin genetic 2 1 1 Negative Genetic, Negative Genetic
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 genetic 2 1 1 Negative Genetic, Negative Genetic
EXG2 YDR261C Exo-1,3-beta-glucanase genetic 2 1 1 Negative Genetic, Negative Genetic
RMA1 YKL132C Putative dihydrofolate synthetase genetic 2 1 1 Negative Genetic, Negative Genetic
ARN1 YHL040C ARN family transporter for siderophore-iron chelates genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
BRF1 YGR246C TFIIIB B-related factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes regulation 1 1 1 chromatin immunoprecipitation-seq evidence
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 1 1 1 Positive Genetic
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Positive Genetic
KAP123 YER110C Karyopherin beta genetic 1 1 1 Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome physical 1 1 1 Co-purification
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Positive Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family genetic 1 1 1 Negative Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
PWP2 YCR057C Conserved 90S pre-ribosomal component physical 1 1 1 Affinity Capture-MS
HCA4 YJL033W DEAD box RNA helicase genetic 1 1 1 Positive Genetic
LSM1 YJL124C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-RNA
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-RNA
TMA64 YDR117C Protein of unknown function that associates with ribosomes physical 1 1 1 Affinity Capture-MS
RRP9 YPR137W Protein involved in pre-rRNA processing physical 1 1 1 Affinity Capture-MS
UTP22 YGR090W Component of the small-subunit processome physical 1 1 1 Affinity Capture-MS
UTP9 YHR196W Nucleolar protein physical 1 1 1 Affinity Capture-MS
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 1 1 1 Affinity Capture-MS
SCD6 YPR129W Repressor of translation initiation physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
SPB4 YFL002C Putative ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
YPR114W YPR114W Protein distantly similar to ceramide synthases, Lag1p and Lac1p physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination physical 1 1 1 Co-purification
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
VSB1 YGR125W Vacuolar membrane protein required for uptake and storage of arginine genetic 1 1 1 Positive Genetic
TIR3 YIL011W Cell wall mannoprotein genetic 1 1 1 Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
TAF8 YML114C TFIID subunit (65 kDa) genetic 1 1 1 Negative Genetic
YPQ1 YOL092W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Negative Genetic
VIK1 YPL253C Protein that forms a kinesin-14 heterodimeric motor with Kar3p genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Positive Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Positive Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
SSF2 YDR312W Protein required for ribosomal large subunit maturation genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Negative Genetic
SPT6 YGR116W Nucleosome remodeling protein genetic 1 1 1 Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
SFI1 YLL003W Centrin (Cdc31p)-binding protein required for SPB duplication genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Negative Genetic
TIF11 YMR260C Translation initiation factor eIF1A genetic 1 1 1 Negative Genetic
SEC8 YPR055W Essential 121 kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
YAR035C-A YAR035C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SCO1 YBR037C Copper-binding protein of mitochondrial inner membrane genetic 1 1 1 Negative Genetic
VID24 YBR105C GID Complex regulatory subunit genetic 1 1 1 Negative Genetic
VHC1 YBR235W Vacuolar membrane cation-chloride cotransporter (CCC) genetic 1 1 1 Negative Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Negative Genetic
SPS22 YCL048W Protein of unknown function genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
YDR194W-A YDR194W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
YDR524C-B YDR524C-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
UTR4 YEL038W Protein with sequence similarity to acireductone synthases genetic 1 1 1 Negative Genetic
TOS3 YGL179C Protein kinase genetic 1 1 1 Negative Genetic
ZIP2 YGL249W Meiosis-specific protein genetic 1 1 1 Negative Genetic
XKS1 YGR194C Xylulokinase genetic 1 1 1 Negative Genetic
YHR022C-A YHR022C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
YIL046W-A YIL046W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Negative Genetic
TMH11 YJR085C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
URA8 YJR103W Minor CTP synthase isozyme (see also URA7) genetic 1 1 1 Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Negative Genetic
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 1 1 1 Negative Genetic
SUL2 YLR092W High affinity sulfate permease genetic 1 1 1 Negative Genetic
YLR464W YLR464W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YNL040W YNL040W Protein of unknown function genetic 1 1 1 Negative Genetic
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 1 1 1 Negative Genetic
TRS33 YOR115C Core component of TRAPP complexes I, II and IV genetic 1 1 1 Negative Genetic
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Negative Genetic
SKI3 YPR189W Ski complex component and TPR protein genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Positive Genetic
SKI8 YGL213C Ski complex component and WD-repeat protein genetic 1 1 1 Negative Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Positive Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 1 1 1 Positive Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
CDC33 YOL139C Translation initiation factor eIF4E physical 1 1 1 Co-purification
CSL4 YNL232W Exosome non-catalytic core component physical 1 1 1 Affinity Capture-MS
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Positive Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RLI1 YDR091C Essential Fe-S protein physical 1 1 1 Affinity Capture-MS
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Phenotypic Suppression
AAR2 YBL074C Component of the U5 snRNP complex genetic 1 1 1 Negative Genetic
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Negative Genetic
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Affinity Capture-MS
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP physical 1 1 1 Affinity Capture-MS
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CDC16 YKL022C Subunit of the anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Synthetic Growth Defect
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Negative Genetic
KGD2 YDR148C Dihydrolipoyl transsuccinylase genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL39 YML009C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
HTA1 YDR225W Histone H2A genetic 1 1 1 Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Negative Genetic
NAB6 YML117W Putative RNA-binding protein genetic 1 1 1 Negative Genetic
NOP14 YDL148C Nucleolar protein physical 1 1 1 Affinity Capture-MS
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
NAS6 YGR232W Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 1 1 1 Affinity Capture-MS
PCI8 YIL071C Possible shared subunit of Cop9 signalosome (CSN) and eIF3 genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Positive Genetic
PRP38 YGR075C Unique component of the U4/U6.U5 tri-snRNP particle genetic 1 1 1 Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Positive Genetic
CCT7 YJL111W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Negative Genetic
FAR8 YMR029C Protein involved in recovery from arrest in response to pheromone genetic 1 1 1 Negative Genetic
LSP1 YPL004C Eisosome core component genetic 1 1 1 Negative Genetic
FIN1 YDR130C Spindle pole body-related intermediate filament protein physical 1 1 1 Affinity Capture-Western
FIN1 YDR130C Spindle pole body-related intermediate filament protein genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Affinity Capture-MS
MGE1 YOR232W Mitochondrial matrix cochaperone genetic 1 1 1 Positive Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
PGM2 YMR105C Phosphoglucomutase genetic 1 1 1 Negative Genetic
PDC6 YGR087C Minor isoform of pyruvate decarboxylase genetic 1 1 1 Negative Genetic
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone genetic 1 1 1 Negative Genetic
DBF20 YPR111W Ser/Thr kinase involved in late nuclear division genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 1 1 1 Negative Genetic
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 1 1 1 Negative Genetic
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription genetic 1 1 1 Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Negative Genetic
GPN3 YLR243W Putative GTPase with a role in biogenesis of RNA pol II and polIII genetic 1 1 1 Positive Genetic
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome genetic 1 1 1 Negative Genetic
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 1 1 1 Negative Genetic
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport genetic 1 1 1 Negative Genetic
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Positive Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
GCY1 YOR120W Glycerol dehydrogenase genetic 1 1 1 Negative Genetic
RPL5 YPL131W Ribosomal 60S subunit protein L5 genetic 1 1 1 Positive Genetic
ASI3 YNL008C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
ADE8 YDR408C Phosphoribosyl-glycinamide transformylase genetic 1 1 1 Negative Genetic
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Negative Genetic
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 1 1 1 Negative Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Negative Genetic
PCL8 YPL219W Cyclin genetic 1 1 1 Negative Genetic
PCL9 YDL179W Cyclin genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
GNP1 YDR508C Broad specificity amino acid permease physical 1 1 1 Affinity Capture-MS
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Positive Genetic
PAL1 YDR348C Protein of unknown function thought to be involved in endocytosis genetic 1 1 1 Negative Genetic
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Negative Genetic
NNF1 YJR112W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Positive Genetic
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Lethality
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Positive Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Positive Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
RPL20B YOR312C Ribosomal 60S subunit protein L20B genetic 1 1 1 Positive Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
ESC1 YMR219W Protein involved in telomeric silencing physical 1 1 1 Affinity Capture-MS
JEM1 YJL073W DnaJ-like chaperone required for nuclear membrane fusion during mating physical 1 1 1 Affinity Capture-MS
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 1 1 1 Negative Genetic
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p genetic 1 1 1 Negative Genetic
RDI1 YDL135C Rho GDP dissociation inhibitor genetic 1 1 1 Negative Genetic
ERV29 YGR284C Protein localized to COPII-coated vesicles physical 1 1 1 Affinity Capture-MS
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
PAN3 YKL025C Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex genetic 1 1 1 Negative Genetic
MID1 YNL291C Stretch-activated Ca2+-permeable cation channel genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Positive Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Phenotypic Suppression
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Positive Genetic
CBS2 YDR197W Mitochondrial translational activator of the COB mRNA genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
MIG2 YGL209W Zinc finger transcriptional repressor genetic 1 1 1 Negative Genetic
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 1 1 1 Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 1 1 1 Positive Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
IAI11 YBL059W Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
CSR1 YLR380W Phosphatidylinositol transfer protein genetic 1 1 1 Negative Genetic
MVB12 YGR206W ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers genetic 1 1 1 Positive Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
JID1 YPR061C Probable Hsp40p co-chaperone genetic 1 1 1 Negative Genetic
AIM23 YJL131C Mitochondrial translation initiation factor 3 (IF3, mIF3) genetic 1 1 1 Negative Genetic
CWH41 YGL027C Processing alpha glucosidase I physical 1 1 1 Affinity Capture-MS
PTM1 YKL039W Protein of unknown function genetic 1 1 1 Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 1 1 1 Negative Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Positive Genetic
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Negative Genetic
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 1 1 1 Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Negative Genetic
MUP1 YGR055W High affinity methionine permease genetic 1 1 1 Negative Genetic
FCY2 YER056C Purine-cytosine permease genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Positive Genetic
BSC1 YDL037C Protein of unconfirmed function genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
ADK2 YER170W Mitochondrial adenylate kinase genetic 1 1 1 Negative Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
NRE1 YIR035C Putative cytoplasmic short-chain dehydrogenase/reductase genetic 1 1 1 Negative Genetic
MTC2 YKL098W Protein of unknown function genetic 1 1 1 Negative Genetic
HSP32 YPL280W Possible chaperone and cysteine protease genetic 1 1 1 Positive Genetic
GPI18 YBR004C Functional ortholog of human PIG-V genetic 1 1 1 Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
PBI1 YPL272C Putative protein of unknown function genetic 1 1 1 Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Negative Genetic
MCP1 YOR228C Mitochondrial protein of unknown function involved in lipid homeostas genetic 1 1 1 Positive Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
KNH1 YDL049C Protein with similarity to Kre9p genetic 1 1 1 Synthetic Growth Defect
FMP30 YPL103C Protein with a role in maintaining mitochondrial morphology genetic 1 1 1 Negative Genetic
ALG8 YOR067C Glucosyl transferase genetic 1 1 1 Phenotypic Suppression
RCI50 YKL133C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic
PDH1 YPR002W Putative 2-methylcitrate dehydratase genetic 1 1 1 Negative Genetic