Standard name Systematic name Name description Description
PAN3 YKL025C Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex; poly (A) mRNA binding subunit which recruits mRNA to the complex; the Pan2p-Pan3p complex controls poly(A) tail length and regulates the stoichiometry and activity of postreplication repair complexes
Visualize the interactome of PAN3
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.972 0.958 0.97

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 1600

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PAN3 5 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PAN2 YGL094C Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex physical 11 6 8 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Two-hybrid, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 7 2 6 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 5 3 5 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 4 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 3 2 2 Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TUB3 YML124C Alpha-tubulin genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PAB1 YER165W Poly(A) binding protein physical 2 2 2 Two-hybrid, Reconstituted Complex
SAC3 YDR159W mRNA export factor genetic 2 2 2 Phenotypic Suppression, Positive Genetic
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
CDC73 YLR418C Component of the Paf1p complex genetic 2 1 2 Negative Genetic, Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
IRA2 YOL081W GTPase-activating protein genetic 2 1 2 Negative Genetic, Negative Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 2 1 2 Negative Genetic, Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 2 2 1 Synthetic Growth Defect, Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 2 1 1 Negative Genetic, Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RSF2 YJR127C Zinc-finger protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BFR2 YDR299W Component of the SSU and 90S preribosomes genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Growth Defect
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Positive Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Synthetic Growth Defect
EMP24 YGL200C Component of the p24 complex genetic 1 1 1 Synthetic Growth Defect
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 1 1 1 Two-hybrid
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 1 1 1 Positive Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Synthetic Growth Defect
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
LTV1 YKL143W Subunit of the EGO/GSE complex genetic 1 1 1 Positive Genetic
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 1 1 1 Negative Genetic
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 1 1 1 Affinity Capture-MS
NGL2 YMR285C Protein involved in 5.8S rRNA processing genetic 1 1 1 Negative Genetic
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase physical 1 1 1 Two-hybrid
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 1 1 1 Synthetic Growth Defect
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Negative Genetic
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Negative Genetic
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Positive Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Negative Genetic
LST7 YGR057C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Positive Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 1 1 1 Negative Genetic
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 1 1 1 Positive Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 1 1 1 Positive Genetic
ITT1 YML068W Protein that modulates the efficiency of translation termination genetic 1 1 1 Positive Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 1 1 1 Synthetic Rescue
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
BPT1 YLL015W ABC type transmembrane transporter of MRP/CFTR family genetic 1 1 1 Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) physical 1 1 1 Two-hybrid
DPC29 YGR021W Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
AZF1 YOR113W Zinc-finger transcription factor genetic 1 1 1 Positive Genetic
RPC10 YHR143W-A RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III physical 1 1 1 Two-hybrid
PAN3 YKL025C Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex physical 1 1 1 Two-hybrid
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p physical 1 1 1 Biochemical Activity
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Synthetic Lethality
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Synthetic Growth Defect
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Synthetic Growth Defect
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Positive Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
PMT6 YGR199W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Positive Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Positive Genetic
TSR2 YLR435W Protein with a potential role in pre-rRNA processing genetic 1 1 1 Positive Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Negative Genetic
THS1 YIL078W Threonyl-tRNA synthetase genetic 1 1 1 Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Negative Genetic
SXM1 YDR395W Nuclear transport factor (karyopherin) genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
SOD2 YHR008C Mitochondrial manganese superoxide dismutase genetic 1 1 1 Negative Genetic
WSS1 YHR134W SUMO-ligase and SUMO-targeted metalloprotease genetic 1 1 1 Negative Genetic
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TPH3 YJL016W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL17B YJL177W Ribosomal 60S subunit protein L17B genetic 1 1 1 Negative Genetic
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 1 1 1 Negative Genetic
TOP3 YLR234W DNA Topoisomerase III genetic 1 1 1 Negative Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
SET6 YPL165C SET domain protein of unknown function genetic 1 1 1 Negative Genetic
YOR072W-B YOR072W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein genetic 1 1 1 Negative Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Negative Genetic
YOR268C YOR268C Putative protein of unknown function genetic 1 1 1 Positive Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Positive Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
CYB5 YNL111C Cytochrome b5 genetic 1 1 1 Negative Genetic
ADE12 YNL220W Adenylosuccinate synthase genetic 1 1 1 Negative Genetic
GLN4 YOR168W Glutamine tRNA synthetase genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
CIS3 YJL158C Mannose-containing glycoprotein constituent of the cell wall genetic 1 1 1 Negative Genetic
ITR1 YDR497C Myo-inositol transporter genetic 1 1 1 Negative Genetic
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type physical 1 1 1 Two-hybrid
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Negative Genetic
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Negative Genetic
MAL33 YBR297W MAL-activator protein genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Negative Genetic