RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
10 |
4 |
9 |
Co-crystal Structure, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
4 |
2 |
4 |
Co-crystal Structure, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
RPA135 |
YPR010C |
RNA polymerase I second largest subunit A135 |
physical |
3 |
2 |
3 |
Two-hybrid, Two-hybrid, Affinity Capture-MS |
RPB8 |
YOR224C |
RNA polymerase subunit ABC14.5 |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
ASR1 |
YPR093C |
Ubiquitin ligase that modifies and regulates RNA Pol II |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
2 |
2 |
Synthetic Rescue, Synthetic Haploinsufficiency, Synthetic Haploinsufficiency |
RPB4 |
YJL140W |
RNA polymerase II subunit B32 |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
2 |
2 |
2 |
Affinity Capture-MS, PCA |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPB7 |
YDR404C |
RNA polymerase II subunit B16 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
HHT1 |
YBR010W |
Histone H3 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RTR1 |
YER139C |
Dual specificity protein phosphatase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
TFC3 |
YAL001C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
TFC4 |
YGR047C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
2 |
2 |
1 |
Two-hybrid, Far Western |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC73 |
YLR418C |
Component of the Paf1p complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
genetic |
1 |
1 |
1 |
Dosage Lethality |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RPA135 |
YPR010C |
RNA polymerase I second largest subunit A135 |
genetic |
1 |
1 |
1 |
Dosage Lethality |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTB2 |
YBL002W |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
PCA |
MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBP2 |
YBR233W |
RNA binding protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB9 |
YGL070C |
RNA polymerase II subunit B12.6 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HTB1 |
YDR224C |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
NPA3 |
YJR072C |
Member of the conserved GPN-loop GTPase family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MUS81 |
YDR386W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
physical |
1 |
1 |
1 |
PCA |
GPN2 |
YOR262W |
Putative GTPase with a specific role in RNA pol II and polIII biogenes |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
GPN2 |
YOR262W |
Putative GTPase with a specific role in RNA pol II and polIII biogenes |
genetic |
1 |
1 |
1 |
Dosage Rescue |
BRF1 |
YGR246C |
TFIIIB B-related factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFC4 |
YGR047C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRB4 |
YER022W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Co-purification |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFG1 |
YGR186W |
TFIIF (Transcription Factor II) largest subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS5 |
YJR123W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GAL4 |
YPL248C |
DNA-binding transcription factor required for activating GAL genes |
physical |
1 |
1 |
1 |
PCA |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAN3 |
YKL025C |
Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
physical |
1 |
1 |
1 |
Two-hybrid |
INA22 |
YIR024C |
F1F0 ATP synthase peripheral stalk assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RBA50 |
YDR527W |
Protein involved in transcription |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |