PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
4 |
1 |
4 |
Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA |
RTC6 |
YPL183W-A |
Protein involved in translation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TMA17 |
YDL110C |
Regulatory gamma subunit of fatty acid synthase (FAS) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PHB1 |
YGR132C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
INA17 |
YPL099C |
F1F0 ATPase synthase peripheral stalk assembly factor |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DAL82 |
YNL314W |
Positive regulator of allophanate inducible genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
physical |
1 |
1 |
1 |
Two-hybrid |
EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
EHD3 |
YDR036C |
3-hydroxyisobutyryl-CoA hydrolase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM17 |
YHL021C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Positive Genetic |
FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CBP3 |
YPL215W |
Mitochondrial protein required for assembly of cytochrome bc1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CBP6 |
YBR120C |
Mitochondrial protein required for translation of the COB mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ARH1 |
YDR376W |
Oxidoreductase of the mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Two-hybrid |
ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX2 |
Q0250 |
Subunit II of cytochrome c oxidase (Complex IV) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
COX1 |
Q0045 |
Subunit I of cytochrome c oxidase (Complex IV) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
COB |
Q0105 |
Cytochrome b |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
COX3 |
Q0275 |
Subunit III of cytochrome c oxidase (Complex IV) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ATP6 |
Q0085 |
Subunit a of the F0 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
COX19 |
YLL018C-A |
Protein required for cytochrome c oxidase assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC10 |
YHR143W-A |
RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OLI1 |
Q0130 |
F0-ATP synthase subunit c (ATPase-associated proteolipid) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
TPO5 |
YKL174C |
Protein involved in excretion of putrescine and spermidine |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Positive Genetic |
TMA64 |
YDR117C |
Protein of unknown function that associates with ribosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRPL8 |
YJL063C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
YMR155W |
YMR155W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
PHO91 |
YNR013C |
Low-affinity vacuolar phosphate transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPL039W |
YPL039W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTR4 |
YJL050W |
RNA duplex-sensing translocase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM50 |
YPL063W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET100 |
YDR079W |
Chaperone that facilitates the assembly of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
REF2 |
YDR195W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
QCR7 |
YDR529C |
Subunit 7 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOM1 |
YEL059C-A |
Subunit of the mitochondrial inner membrane peptidase (IMP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
OXA1 |
YER154W |
Mitochondrial inner membrane insertase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAR029W |
YAR029W |
Member of DUP240 gene family but contains no transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX10 |
YDR265W |
Peroxisomal membrane E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIL161W |
YIL161W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL107C |
YJL107C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIR5 |
YJL160C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR415C |
YLR415C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOL1 |
YNR034W |
Protein with a possible role in tRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM12 |
YOL009C |
Mitochondrial outer membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL057W |
YOL057W |
Dipeptidyl-peptidase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET127 |
YOR017W |
Protein with a role in 5'-end processing of mitochondrial RNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
WHI5 |
YOR083W |
Repressor of G1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSC1 |
YOR142W |
Alpha subunit of succinyl-CoA ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGR2 |
YPL098C |
Subunit of the TIM23 translocase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LTP1 |
YPR073C |
Protein phosphotyrosine phosphatase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRP49 |
YKL167C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET309 |
YLR067C |
Specific translational activator for the COX1 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
QRI5 |
YLR204W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET111 |
YMR257C |
Mitochondrial translational activator specific for the COX2 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
MFA2 |
YNL145W |
Mating pheromone a-factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GIS1 |
YDR096W |
Histone demethylase and transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IFM1 |
YOL023W |
Mitochondrial translation initiation factor 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP8 |
Q0080 |
Subunit 8 of the F0 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CBP4 |
YGR174C |
Mitochondrial protein required for assembly of cytochrome bc1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CMC2 |
YBL059C-A |
Protein involved in respiratory chain complex assembly or maintenance |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPI8 |
YJL133C-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
HMX1 |
YLR205C |
ER localized heme oxygenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Dosage Rescue |
FMT1 |
YBL013W |
Methionyl-tRNA formyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |