SPC97 |
YHR172W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
physical |
25 |
5 |
16 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, FRET, FRET, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
SPC98 |
YNL126W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
physical |
11 |
4 |
8 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western |
SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
physical |
11 |
5 |
6 |
Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Co-purification, FRET, FRET, Affinity Capture-Western, Reconstituted Complex |
SPC72 |
YAL047C |
Gamma-tubulin small complex (gamma-TuSC) receptor |
physical |
9 |
5 |
5 |
Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Co-localization, Reconstituted Complex, Co-fractionation |
SPC98 |
YNL126W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
genetic |
8 |
4 |
4 |
Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Phenotypic Suppression, Phenotypic Enhancement |
MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
6 |
3 |
5 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
3 |
3 |
3 |
Negative Genetic, Positive Genetic, Synthetic Rescue |
DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect |
ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
3 |
3 |
2 |
Synthetic Lethality, Synthetic Rescue, Synthetic Growth Defect |
UBA3 |
YPR066W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
3 |
3 |
2 |
Negative Genetic, Synthetic Rescue, Synthetic Growth Defect |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
2 |
2 |
Synthetic Haploinsufficiency, Synthetic Haploinsufficiency, Negative Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Rescue |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
TIF1 |
YKR059W |
Translation initiation factor eIF4A |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Rescue |
RAD1 |
YPL022W |
Single-stranded DNA endonuclease (with Rad10p) |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Growth Defect |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Positive Genetic |
MAD3 |
YJL013C |
Subunit of spindle-assembly checkpoint complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SPC72 |
YAL047C |
Gamma-tubulin small complex (gamma-TuSC) receptor |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Growth Defect |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Growth Defect |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
HTD2 |
YHR067W |
Mitochondrial 3-hydroxyacyl-thioester dehydratase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Rescue |
IRC25 |
YLR021W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Growth Defect |
CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Rescue |
RTC6 |
YPL183W-A |
Protein involved in translation |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Rescue |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RTT10 |
YPL183C |
WD40 domain-containing protein involved in endosomal recycling |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
2 |
2 |
1 |
PCA, Biochemical Activity |
AEP2 |
YMR282C |
Mitochondrial protein |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
SKI3 |
YPR189W |
Ski complex component and TPR protein |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
RHO2 |
YNL090W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
ATG29 |
YPL166W |
Autophagy-specific protein |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
PST2 |
YDR032C |
FMN-dependent NAD(P)H:quinone oxidoreductase |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
BEM3 |
YPL115C |
Rho GTPase activating protein (RhoGAP) |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
HUA2 |
YOR284W |
Cytoplasmic protein of unknown function |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
YPL225W |
YPL225W |
Protein of unknown function |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
YOR342C |
YOR342C |
Protein of unknown function |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
TUM1 |
YOR251C |
Rhodanese domain sulfur transferase |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
YPR071W |
YPR071W |
Putative membrane protein |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
physical |
2 |
2 |
1 |
Reconstituted Complex, Co-fractionation |
RPL33B |
YOR234C |
Ribosomal 60S subunit protein L33B |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
RTT106 |
YNL206C |
Histone chaperone |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
MDM38 |
YOL027C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
DYN3 |
YMR299C |
Dynein light intermediate chain (LIC) |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
FSF1 |
YOR271C |
Putative protein |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
STP1 |
YDR463W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE1 |
YLR007W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NOP16 |
YER002W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HOL1 |
YNR055C |
Putative transporter in the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
NUC1 |
YJL208C |
Major mitochondrial nuclease |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PUS7 |
YOR243C |
Pseudouridine synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPS4B |
YHR203C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF2 |
YJL138C |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TEX1 |
YNL253W |
Protein involved in mRNA export |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RSC2 |
YLR357W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PUF6 |
YDR496C |
Pumilio-homology domain protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TSR2 |
YLR435W |
Protein with a potential role in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ADE4 |
YMR300C |
Phosphoribosylpyrophosphate amidotransferase (PRPPAT) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP11 |
YNL315C |
Molecular chaperone |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HAP2 |
YGL237C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HAT1 |
YPL001W |
Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HIS4 |
YCL030C |
Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HST1 |
YOL068C |
NAD(+)-dependent histone deacetylase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
IOC3 |
YFR013W |
Subunit of the Isw1a complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
KGD1 |
YIL125W |
Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAL12 |
YGR292W |
Maltase (alpha-D-glucosidase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MBP1 |
YDL056W |
Transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM10 |
YAL010C |
Subunit of both the ERMES and the SAM complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EHD3 |
YDR036C |
3-hydroxyisobutyryl-CoA hydrolase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MLC2 |
YPR188C |
Regulatory light chain for the type II myosin Myo1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CMD1 |
YBR109C |
Calmodulin |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HER1 |
YOR227W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
NPL4 |
YBR170C |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ADE57 |
YGL234W |
Bifunctional enzyme of 'de novo' purine nucleotide pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RKM1 |
YPL208W |
SET-domain lysine-N-methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL2A |
YFR031C-A |
Ribosomal 60S subunit protein L2A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SGN1 |
YIR001C |
Cytoplasmic RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HOS4 |
YIL112W |
Subunit of the Set3 complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AVT4 |
YNL101W |
Vacuolar transporter |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HRK1 |
YOR267C |
Protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BSP1 |
YPR171W |
Adapter that links synaptojanins to the cortical actin cytoskeleton |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLC1 |
YDL052C |
1-acyl-sn-glycerol-3-phosphate acyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPE3 |
YPR069C |
Spermidine synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC65 |
YML105C |
Subunit of the signal recognition particle (SRP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
CAM1 |
YPL048W |
One of two isoforms of the gamma subunit of eEF1B |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
TKL1 |
YPR074C |
Transketolase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TRP2 |
YER090W |
Anthranilate synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPC97 |
YHR172W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ECM30 |
YLR436C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ALT2 |
YDR111C |
Catalytically inactive alanine transaminase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SAW1 |
YAL027W |
5'- and 3'-flap DNA binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPP1 |
YPL138C |
Subunit of COMPASS (Set1C) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
LYS9 |
YNR050C |
Saccharopine dehydrogenase (NADP+, L-glutamate-forming) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CIR2 |
YOR356W |
Putative ortholog of human ETF-dH |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM41 |
YOR215C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LSP1 |
YPL004C |
Eisosome core component |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FET4 |
YMR319C |
Low-affinity Fe(II) transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PPQ1 |
YPL179W |
Protein phosphatase that regulates the mating response |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ATG31 |
YDR022C |
Autophagy-specific protein required for autophagosome formation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AAC3 |
YBR085W |
Mitochondrial inner membrane ADP/ATP translocator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PRB1 |
YEL060C |
Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SER1 |
YOR184W |
3-phosphoserine aminotransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CNA1 |
YLR433C |
Calcineurin A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CNB1 |
YKL190W |
Calcineurin B |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GDE1 |
YPL110C |
Glycerophosphocholine (GroPCho) phosphodiesterase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FKH1 |
YIL131C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FDO1 |
YMR144W |
Protein involved in directionality of mating type switching |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EGD1 |
YPL037C |
Subunit beta1 of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AMF1 |
YOR378W |
Low affinity NH4+ transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ENV7 |
YPL236C |
Vacuolar membrane protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAS1 |
YOR101W |
GTPase involved in G-protein signaling in adenylate cyclase activation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
DDC1 |
YPL194W |
DNA damage checkpoint protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARG4 |
YHR018C |
Argininosuccinate lyase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
OM45 |
YIL136W |
Mitochondrial outer membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SOD2 |
YHR008C |
Mitochondrial manganese superoxide dismutase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
APT1 |
YML022W |
Adenine phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AIP1 |
YMR092C |
Actin cortical patch component |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
DAS1 |
YJL149W |
Putative SCF ubiquitin ligase F-box protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GID8 |
YMR135C |
Subunit of GID Complex, binds strongly to central component Vid30p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PSK2 |
YOL045W |
PAS-domain containing serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ATG7 |
YHR171W |
Autophagy-related protein and dual specificity member of the E1 family |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ETP1 |
YHL010C |
Protein of unknown function required for growth on ethanol |
physical |
1 |
1 |
1 |
Two-hybrid |
FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
LTP1 |
YPR073C |
Protein phosphotyrosine phosphatase of unknown cellular role |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LRO1 |
YNR008W |
Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PEX6 |
YNL329C |
AAA-peroxin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PBA1 |
YLR199C |
Protein involved in 20S proteasome assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TMA19 |
YKL056C |
Protein that associates with ribosomes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PTC7 |
YHR076W |
Type 2C serine/threonine protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AIM46 |
YHR199C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PDX1 |
YGR193C |
E3-binding protein of the mitochondrial pyruvate dehydrogenase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ARE1 |
YCR048W |
Acyl-CoA:sterol acyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
FAA1 |
YOR317W |
Long chain fatty acyl-CoA synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ISU1 |
YPL135W |
Conserved protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HHO1 |
YPL127C |
Histone H1, linker histone with roles in meiosis and sporulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MEK1 |
YOR351C |
Meiosis-specific serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BUD7 |
YOR299W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SMK1 |
YPR054W |
Middle sporulation-specific mitogen-activated protein kinase (MAPK) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
LSC1 |
YOR142W |
Alpha subunit of succinyl-CoA ligase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MIH1 |
YMR036C |
Protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PTP2 |
YOR208W |
Phosphotyrosine-specific phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AHC1 |
YOR023C |
Subunit of the Ada histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SKM1 |
YOL113W |
Member of the PAK family of serine/threonine protein kinases |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SNO2 |
YNL334C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NDE1 |
YMR145C |
Mitochondrial external NADH dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LOS1 |
YKL205W |
Nuclear pore protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVT2 |
YEL064C |
Putative transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MSG5 |
YNL053W |
Dual-specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUF1 |
YOL087C |
Ubiquitin-binding protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LEM3 |
YNL323W |
Membrane protein of the plasma membrane and ER |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CBR1 |
YIL043C |
Cytochrome b reductase and NADH-dependent reductase for Dph3p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ADH6 |
YMR318C |
NADPH-dependent medium chain alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PRS5 |
YOL061W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RIM11 |
YMR139W |
Protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
DAP1 |
YPL170W |
Heme-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GCY1 |
YOR120W |
Glycerol dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MET16 |
YPR167C |
3'-phosphoadenylsulfate reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ROD1 |
YOR018W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RAD28 |
YDR030C |
Protein involved in DNA repair |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
JJJ1 |
YNL227C |
Co-chaperone that stimulates the ATPase activity of Ssa1p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RED1 |
YLR263W |
Protein component of the synaptonemal complex axial elements |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PSO2 |
YMR137C |
Nuclease required for DNA single- and double-strand break repair |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CRC1 |
YOR100C |
Mitochondrial inner membrane carnitine transporter |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUE5 |
YOR042W |
Ubiquitin-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SNZ2 |
YNL333W |
Protein involved in thiamine and pyridoxine biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PEX29 |
YDR479C |
ER-resident protein involved in peroxisomal biogenesis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ADE8 |
YDR408C |
Phosphoribosyl-glycinamide transformylase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CIN4 |
YMR138W |
GTP-binding protein involved in beta-tubulin (Tub2p) folding |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ECM31 |
YBR176W |
Ketopantoate hydroxymethyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ARG81 |
YML099C |
Zinc finger transcription factor involved in arginine-responsive genes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GDS1 |
YOR355W |
Protein involved in histone H4 acetylation at ribosomal protein genes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ISU2 |
YOR226C |
Mitochondrial protein required for iron-sulfur protein synthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MPD2 |
YOL088C |
Member of the protein disulfide isomerase (PDI) family |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEX21 |
YGR239C |
Peroxin required for peroxisomal matrix protein targeting |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CLG1 |
YGL215W |
Cyclin-like protein that interacts with Pho85p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PCL8 |
YPL219W |
Cyclin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PPG1 |
YNR032W |
Serine protein phosphatase involved in formation of FAR complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RGA1 |
YOR127W |
GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RRN10 |
YBL025W |
Protein involved in promoting high level transcription of rDNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATG34 |
YOL083W |
Receptor protein involved in selective autophagy during starvation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GNP1 |
YDR508C |
Broad specificity amino acid permease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SKI8 |
YGL213C |
Ski complex component and WD-repeat protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PFS1 |
YHR185C |
Sporulation protein required for prospore membrane formation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SSP1 |
YHR184W |
Protein involved in the control of meiotic nuclear division |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
STD1 |
YOR047C |
Protein involved in control of glucose-regulated gene expression |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRM3 |
YPL192C |
Protein required for nuclear envelope fusion during karyogamy |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
DAS2 |
YDR020C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STB2 |
YMR053C |
Protein that interacts with Sin3p in a two-hybrid assay |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SNA3 |
YJL151C |
Protein involved in efficient MVB sorting of proteins to the vacuole |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PRM9 |
YAR031W |
Pheromone-regulated protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LAM6 |
YLR072W |
Sterol transporter that transfers sterols between membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
ITT1 |
YML068W |
Protein that modulates the efficiency of translation termination |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SWM2 |
YNR004W |
Protein with a role in snRNA and snoRNA cap trimethylation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
FMP40 |
YPL222W |
Mitochondrial AMPylator in the pseudokinase selenoprotein-O family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GIP3 |
YPL137C |
Cytoplasmic protein that regulates protein phosphatase 1 Glc7p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEX17 |
YNL214W |
Membrane peroxin of the peroxisomal importomer complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPS4A |
YJR145C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL9A |
YGL147C |
Ribosomal 60S subunit protein L9A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPL9B |
YNL067W |
Ribosomal 60S subunit protein L9B |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HOS3 |
YPL116W |
Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPL20B |
YOR312C |
Ribosomal 60S subunit protein L20B |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ELO3 |
YLR372W |
Elongase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HOS1 |
YPR068C |
Class I histone deacetylase (HDAC) family member |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
physical |
1 |
1 |
1 |
Reconstituted Complex |
KAR9 |
YPL269W |
Spindle positioning factor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PEA2 |
YER149C |
Coiled-coil 12S polarisome subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PNG1 |
YPL096W |
Conserved peptide N-glycanase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PUP1 |
YOR157C |
Beta 2 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFM1 |
YOR279C |
Component of the Sum1p-Rfm1p-Hst1p complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TIM18 |
YOR297C |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TUB4 |
YLR212C |
Gamma-tubulin |
physical |
1 |
1 |
1 |
Two-hybrid |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKL075C |
YKL075C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR053C |
YLR053C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YMD8 |
YML038C |
Putative nucleotide sugar transporter |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VAC14 |
YLR386W |
Enzyme regulator |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YTP1 |
YNL237W |
Probable type-III integral membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
URA5 |
YML106W |
Major orotate phosphoribosyltransferase (OPRTase) isozyme |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YNR029C |
YNR029C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YIM1 |
YMR152W |
Aldehyde reductase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YML108W |
YML108W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YNR021W |
YNR021W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YVC1 |
YOR087W |
Vacuolar cation channel |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YJL206C |
YJL206C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YAP1801 |
YHR161C |
Protein of the AP180 family, involved in clathrin cage assembly |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YJL213W |
YJL213W |
Protein of unknown function that may interact with ribosomes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YHL008C |
YHL008C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VID30 |
YGL227W |
Central component of GID Complex, involved in FBPase degradation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YIL165C |
YIL165C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
UBC8 |
YEL012W |
Ubiquitin-conjugating enzyme that regulates gluconeogenesis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YSP3 |
YOR003W |
Putative precursor of the subtilisin-like protease III |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VID28 |
YIL017C |
GID Complex subunit, serves as adaptor for regulatory subunit Vid24p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YHR022C |
YHR022C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
URA4 |
YLR420W |
Dihydroorotase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YHL017W |
YHL017W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YGR111W |
YGR111W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YHM2 |
YMR241W |
Citrate and oxoglutarate carrier protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YML053C |
YML053C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YFL012W |
YFL012W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YOR111W |
YOR111W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YIL152W |
YIL152W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YHR033W |
YHR033W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YNL134C |
YNL134C |
NADH-dependent aldehyde reductase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YML037C |
YML037C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TWF1 |
YGR080W |
Twinfilin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YOR019W |
YOR019W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YOL057W |
YOL057W |
Dipeptidyl-peptidase III |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YNR014W |
YNR014W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YOR012W |
YOR012W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
WAR1 |
YML076C |
Homodimeric Zn2Cys6 zinc finger transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YKE4 |
YIL023C |
Zinc transporter |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VID24 |
YBR105C |
GID Complex regulatory subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YOL163W |
YOL163W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YHK8 |
YHR048W |
Presumed antiporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
WSC4 |
YHL028W |
Endoplasmic reticulum (ER) membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YOX1 |
YML027W |
Homeobox transcriptional repressor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YOR062C |
YOR062C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YNL190W |
YNL190W |
Hydrophilin essential in desiccation-rehydration process |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YJL193W |
YJL193W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
UBC7 |
YMR022W |
Ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YBR238C |
YBR238C |
Mitochondrial membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YIL060W |
YIL060W |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
UBP12 |
YJL197W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YIR016W |
YIR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YMR226C |
YMR226C |
NADP(+)-dependent serine dehydrogenase and carbonyl reductase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YSA1 |
YBR111C |
Nudix hydrolase family member with ADP-ribose pyrophosphatase activity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VIK1 |
YPL253C |
Protein that forms a kinesin-14 heterodimeric motor with Kar3p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YGL081W |
YGL081W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YER084W |
YER084W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPT7 |
YML001W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YOR338W |
YOR338W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YEH2 |
YLR020C |
Steryl ester hydrolase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ZRT2 |
YLR130C |
Low-affinity zinc transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YDL211C |
YDL211C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YLR036C |
YLR036C |
Putative protein predicted to have transmembrane domains |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YNG1 |
YOR064C |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBC11 |
YOR339C |
Ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YTA6 |
YPL074W |
Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VTC3 |
YPL019C |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YDC1 |
YPL087W |
Alkaline dihydroceramidase, involved in sphingolipid metabolism |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YIG1 |
YPL201C |
Protein that interacts with glycerol 3-phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBP16 |
YPL072W |
Deubiquitinating enzyme anchored to the outer mitochondrial membrane |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOR289W |
YOR289W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ULA1 |
YPL003W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPR148C |
YPR148C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPL068C |
YPL068C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOR365C |
YOR365C |
Putative protein involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YDR042C |
YDR042C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPL113C |
YPL113C |
Glyoxylate reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
WTM2 |
YOR229W |
Transcriptional modulator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOR385W |
YOR385W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPL088W |
YPL088W |
Putative aryl alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPL257W |
YPL257W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOL153C |
YOL153C |
Blocked reading frame, contains two in-frame stops in translation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YEL023C |
YEL023C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPL071C |
YPL071C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TYW1 |
YPL207W |
Iron-sulfur protein required for synthesis of wybutosine modified tRNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
WSS1 |
YHR134W |
SUMO-ligase and SUMO-targeted metalloprotease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YAP1802 |
YGR241C |
Protein of the AP180 family, involved in clathrin cage assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPL199C |
YPL199C |
Protein involved in nonstop mRNA decay |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VSB1 |
YGR125W |
Vacuolar membrane protein required for uptake and storage of arginine |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
WTM1 |
YOR230W |
Transcriptional modulator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOR283W |
YOR283W |
Phosphatase with a broad substrate specificity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPL108W |
YPL108W |
Cytoplasmic protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPR027C |
YPR027C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOR268C |
YOR268C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ZEO1 |
YOL109W |
Peripheral membrane protein of the plasma membrane |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPL216W |
YPL216W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UIP4 |
YPL186C |
Protein that interacts with Ulp1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPL191C |
YPL191C |
K48-specific deubiquitinating (DUB) enzyme |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TYE7 |
YOR344C |
Serine-rich protein that contains a bHLH DNA binding motif |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOR296W |
YOR296W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YDR109C |
YDR109C |
D-ribulokinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
USV1 |
YPL230W |
Putative transcription factor containing a C2H2 zinc finger |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOR238W |
YOR238W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YMC1 |
YPR058W |
Secondary mitochondrial inner membrane glycine transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOP1 |
YPR028W |
Reticulon-interacting protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATG2 |
YNL242W |
Peripheral membrane protein required for autophagic vesicle formation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
DPH2 |
YKL191W |
Protein required for synthesis of diphthamide |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HRB1 |
YNL004W |
Poly(A+) RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PHO2 |
YDL106C |
Homeobox transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST6 |
YML019W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MBF1 |
YOR298C-A |
Transcriptional coactivator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TRS33 |
YOR115C |
Core component of TRAPP complexes I, II and IV |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSO1 |
YNR049C |
Lipid-interacting protein in SNARE complex assembly machinery |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RBL2 |
YOR265W |
Protein involved in microtubule morphogenesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARG80 |
YMR042W |
Transcription factor involved in regulating arginine-responsive genes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CHS3 |
YBR023C |
Chitin synthase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESC1 |
YMR219W |
Protein involved in telomeric silencing |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GNT1 |
YOR320C |
N-acetylglucosaminyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DBP1 |
YPL119C |
ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DCN1 |
YLR128W |
Scaffold-type E3 ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BCH1 |
YMR237W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
EMA17 |
YIL029C |
Protein involved in targeting mitochondrial membrane protein precursor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEX25 |
YPL112C |
Peripheral peroxisomal membrane peroxin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEX28 |
YHR150W |
Peroxisomal integral membrane peroxin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMR2 |
YOR093C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RLM1 |
YPL089C |
MADS-box transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARK1 |
YNL020C |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MKK1 |
YOR231W |
MAPKK involved in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPA2 |
YLL021W |
Component of the polarisome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TEA1 |
YOR337W |
Ty1 enhancer activator involved in Ty enhancer-mediated transcription |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEX27 |
YOR193W |
Peripheral peroxisomal membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SAM2 |
YDR502C |
S-adenosylmethionine synthetase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPL1A |
YPL220W |
Ribosomal 60S subunit protein L1A |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPO21 |
YOL091W |
Component of the meiotic outer plaque of the spindle pole body |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENT2 |
YLR206W |
Epsin-like protein required for endocytosis and actin patch assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
REV3 |
YPL167C |
Catalytic subunit of DNA polymerase zeta |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ALG5 |
YPL227C |
UDP-glucose:dolichyl-phosphate glucosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TCO89 |
YPL180W |
Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CCH1 |
YGR217W |
Voltage-gated high-affinity calcium channel |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
KAR1 |
YNL188W |
Protein involved in karyogamy and spindle pole body duplication |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CQD1 |
YPL109C |
UbiB family mitochondrial protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TOF2 |
YKR010C |
Protein required for rDNA silencing and mitotic rDNA condensation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ASH1 |
YKL185W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
COX17 |
YLL009C |
Copper metallochaperone that transfers copper to Sco1p and Cox11p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KEX2 |
YNL238W |
Kexin, a subtilisin-like protease (proprotein convertase) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HPA2 |
YPR193C |
Tetrameric histone acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ERV29 |
YGR284C |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
REC8 |
YPR007C |
Meiosis-specific component of the sister chromatid cohesion complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PMT3 |
YOR321W |
Protein O-mannosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TCB1 |
YOR086C |
Lipid-binding ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MDL1 |
YLR188W |
Mitochondrial inner membrane half-type ABC transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ENV11 |
YGR071C |
Protein proposed to be involved in vacuolar functions |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MNN14 |
YJR061W |
Protein required for N-glycan mannosylphosphorylation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GSM1 |
YJL103C |
Putative zinc cluster protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MNT4 |
YNR059W |
Putative alpha-1,3-mannosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
KAP120 |
YPL125W |
Karyopherin responsible for the nuclear import of Rpf1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ASN1 |
YPR145W |
Asparagine synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CIN2 |
YPL241C |
GTPase-activating protein (GAP) for Cin4p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL11B |
YGR085C |
Ribosomal 60S subunit protein L11B |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HUB1 |
YNR032C-A |
Ubiquitin-like protein modifier |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
COX14 |
YML129C |
Mitochondrial cytochrome c oxidase (complex IV) assembly factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CLB3 |
YDL155W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TUB1 |
YML085C |
Alpha-tubulin |
physical |
1 |
1 |
1 |
Co-localization |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDR12 |
YPL058C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AQR1 |
YNL065W |
Plasma membrane transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EFT1 |
YOR133W |
Elongation factor 2 (EF-2), also encoded by EFT2 |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PER33 |
YLR064W |
Protein that localizes to the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPL13A |
YDL082W |
Ribosomal 60S subunit protein L13A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MDM31 |
YHR194W |
Mitochondrial protein that may have a role in phospholipid metabolism |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL29 |
YFR032C-A |
Ribosomal 60S subunit protein L29 |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ERG5 |
YMR015C |
C-22 sterol desaturase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MMT2 |
YPL224C |
Putative metal transporter involved in mitochondrial iron accumulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MIT1 |
YEL007W |
Transcriptional regulator of pseudohyphal growth |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRR1 |
YLR213C |
Putative glycoside hydrolase of the spore wall envelope |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
REV1 |
YOR346W |
Deoxycytidyl transferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ARO8 |
YGL202W |
Aromatic aminotransferase I |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KIP2 |
YPL155C |
Kinesin-related motor protein involved in mitotic spindle positioning |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GPB1 |
YOR371C |
Multistep regulator of cAMP-PKA signaling |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GLR1 |
YPL091W |
Cytosolic and mitochondrial glutathione oxidoreductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATP18 |
YML081C-A |
Subunit of the mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PIH1 |
YHR034C |
Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ADE1 |
YAR015W |
N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FMO1 |
YHR176W |
Flavin-containing monooxygenase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ATF1 |
YOR377W |
Alcohol acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARR3 |
YPR201W |
Plasma membrane metalloid/H+ antiporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DUS3 |
YLR401C |
Dihydrouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCH2 |
YKR027W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NDJ1 |
YOL104C |
Protein that regulates meiotic SPB cohesion and telomere clustering |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SIA1 |
YOR137C |
Protein of unassigned function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CAN1 |
YEL063C |
Plasma membrane arginine permease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MF(ALPHA)1 |
YPL187W |
Mating pheromone alpha-factor, made by alpha cells |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PYK2 |
YOR347C |
Pyruvate kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCE102 |
YPR149W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ASE1 |
YOR058C |
Mitotic spindle midzone-localized microtubule bundling protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TIP1 |
YBR067C |
Major cell wall mannoprotein with possible lipase activity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL43B |
YJR094W-A |
Ribosomal 60S subunit protein L43B |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
FRE3 |
YOR381W |
Ferric reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
PHR1 |
YOR386W |
DNA photolyase involved in photoreactivation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DSE4 |
YNR067C |
Daughter cell-specific secreted protein with similarity to glucanases |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
COQ10 |
YOL008W |
Coenzyme Q (ubiquinone) binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PIP2 |
YOR363C |
Autoregulatory, oleate-activated transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NAT5 |
YOR253W |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD34 |
YDR314C |
Protein involved in nucleotide excision repair (NER) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PUF4 |
YGL014W |
Member of the PUF protein family |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
STP1 |
YDR463W |
Transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
JIP4 |
YDR475C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
COQ11 |
YLR290C |
Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DDR48 |
YMR173W |
DNA damage-responsive protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HIS2 |
YFR025C |
Histidinolphosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATG38 |
YLR211C |
Homodimeric subunit of autophagy-specific PtdIns-3-kinase complex I |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CUE3 |
YGL110C |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MET12 |
YPL023C |
Protein with MTHFR activity in vitro |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MPP6 |
YNR024W |
Nuclear exosome-associated RNA binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MVB12 |
YGR206W |
ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
IRC3 |
YDR332W |
Double-stranded DNA-dependent helicase of the DExH/D-box family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BIO2 |
YGR286C |
Biotin synthase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MRP35 |
YNL122C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
LYS14 |
YDR034C |
Transcriptional activator involved in regulating lysine biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NDT80 |
YHR124W |
Meiosis-specific transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
INA22 |
YIR024C |
F1F0 ATP synthase peripheral stalk assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RTC4 |
YNL254C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IZH3 |
YLR023C |
Membrane protein involved in zinc ion homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MUK1 |
YPL070W |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CGI121 |
YML036W |
Component of the EKC/KEOPS complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPP1A |
YDL081C |
Ribosomal stalk protein P1 alpha |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPL37A |
YLR185W |
Ribosomal 60S subunit protein L37A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
KIN4 |
YOR233W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
INA17 |
YPL099C |
F1F0 ATPase synthase peripheral stalk assembly factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS25B |
YLR333C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MDM36 |
YPR083W |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM3 |
YOR092W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ANY1 |
YMR010W |
Protein involved in phospholipid flippase function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HFD1 |
YMR110C |
Dehydrogenase involved in ubiquinone and sphingolipid metabolism |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL42A |
YNL162W |
Ribosomal 60S subunit protein L42A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ERV2 |
YPR037C |
Flavin-linked sulfhydryl oxidase localized to the ER lumen |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SHM2 |
YLR058C |
Cytosolic serine hydroxymethyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NPT1 |
YOR209C |
Nicotinate phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MRS2 |
YOR334W |
Mitochondrial inner membrane Mg(2+) channel |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ALD4 |
YOR374W |
Mitochondrial aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SYH1 |
YPL105C |
Protein of unknown function that influences nuclear pore distribution |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RDS2 |
YPL133C |
Transcription factor involved in regulating gluconeogenesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IDP3 |
YNL009W |
Peroxisomal NADP-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
KRE28 |
YDR532C |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
LDB19 |
YOR322C |
Alpha-arrestin, Ub-ligase adaptor for Rsp5p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MSS18 |
YPR134W |
Nuclear encoded protein needed for splicing of mitochondrial intron |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARO3 |
YDR035W |
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL24A |
YGL031C |
Ribosomal 60S subunit protein L24A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SDD3 |
YOL098C |
Putative metalloprotease |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPL7B |
YPL198W |
Ribosomal 60S subunit protein L7B |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL8B |
YLL045C |
Ribosomal 60S subunit protein L8A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PMS1 |
YNL082W |
ATP-binding protein required for mismatch repair |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RTR1 |
YER139C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS21A |
YKR057W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CHS6 |
YJL099W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SQS1 |
YNL224C |
Protein that stimulates the ATPase and helicase activities of Prp43p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GVP36 |
YIL041W |
BAR domain protein that localizes to early and late Golgi vesicles |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPP2A |
YOL039W |
Ribosomal protein P2 alpha |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL36A |
YMR194W |
Ribosomal 60S subunit protein L36A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS29B |
YDL061C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPL34A |
YER056C-A |
Ribosomal 60S subunit protein L34A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ABP140 |
YOR239W |
AdoMet-dependent tRNA methyltransferase and actin binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATG21 |
YPL100W |
Phosphoinositide binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AIM29 |
YKR074W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ARN2 |
YHL047C |
Transporter |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ABM1 |
YJR108W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PHO91 |
YNR013C |
Low-affinity vacuolar phosphate transporter |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
IRC23 |
YOR044W |
Protein of unknown function involved in multidrug resistance |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AIM39 |
YOL053W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HIS5 |
YIL116W |
Histidinol-phosphate aminotransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PIB2 |
YGL023C |
Phosphatidylinositol 3-phosphate binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RNY1 |
YPL123C |
Vacuolar RNase of the T(2) family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TMA22 |
YJR014W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
DIA1 |
YMR316W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LCL1 |
YPL056C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TIP41 |
YPR040W |
Tap42p-interacting protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ECM7 |
YLR443W |
Putative integral membrane protein with a role in calcium uptake |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SIT1 |
YEL065W |
Ferrioxamine B transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PNT1 |
YOR266W |
Mitochondrial integral inner membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TOS4 |
YLR183C |
Putative transcription factor, contains Forkhead Associated domain |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SMF1 |
YOL122C |
Divalent metal ion transporter |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TRI1 |
YMR233W |
Non-essential sumoylated protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RGS2 |
YOR107W |
Negative regulator of glucose-induced cAMP signaling |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS18B |
YML026C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SGE1 |
YPR198W |
Plasma membrane multidrug transporter |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
COX10 |
YPL172C |
Heme A:farnesyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NRM1 |
YNR009W |
Transcriptional co-repressor of MBF-regulated gene expression |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS27B |
YHR021C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SNX3 |
YOR357C |
Sorting nexin for late-Golgi enzymes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EST2 |
YLR318W |
Reverse transcriptase subunit of the telomerase holoenzyme |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ASI1 |
YMR119W |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
OSW1 |
YOR255W |
Protein involved in sporulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RRT2 |
YBR246W |
Methylesterase performing penultimate step of diphthamide biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEX31 |
YGR004W |
Peroxisomal integral membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
THR1 |
YHR025W |
Homoserine kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
APE4 |
YHR113W |
Cytoplasmic aspartyl aminopeptidase with possible vacuole function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RSF1 |
YMR030W |
Protein required for respiratory growth |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
COQ2 |
YNR041C |
Para hydroxybenzoate polyprenyl transferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PNC1 |
YGL037C |
Nicotinamidase that converts nicotinamide to nicotinic acid |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PNP1 |
YLR209C |
Purine nucleoside phosphorylase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RDL1 |
YOR285W |
Thiosulfate sulfurtransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EEB1 |
YPL095C |
Acyl-coenzymeA:ethanol O-acyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPO11 |
YHL022C |
Meiosis-specific protein required for meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCR2 |
YDR003W |
Vacuolar ubiquitin ligase-substrate adaptor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NPR1 |
YNL183C |
Protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPS16B |
YDL083C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ARF3 |
YOR094W |
Glucose-repressible ADP-ribosylation factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HXT2 |
YMR011W |
High-affinity glucose transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
FRE1 |
YLR214W |
Ferric reductase and cupric reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SUR7 |
YML052W |
Plasma membrane protein, component of eisosomes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AIM34 |
YMR003W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRY1 |
YJL079C |
Lipid binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MET8 |
YBR213W |
Bifunctional dehydrogenase and ferrochelatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FLC1 |
YPL221W |
Flavin adenine dinucleotide transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DUR3 |
YHL016C |
Plasma membrane transporter for both urea and polyamines |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RBS1 |
YDL189W |
Protein involved in assembly of the RNA Pol III complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPO19 |
YPL130W |
Meiosis-specific prospore protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CGR1 |
YGL029W |
Protein involved in nucleolar integrity and processing of pre-rRNA |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PIN2 |
YOR104W |
Exomer-dependent cargo protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TPO4 |
YOR273C |
Polyamine transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ALG12 |
YNR030W |
Alpha-1,6-mannosyltransferase localized to the ER |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SHR5 |
YOL110W |
Palmitoyltransferase subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DCW1 |
YKL046C |
Putative mannosidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ARO7 |
YPR060C |
Chorismate mutase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLM4 |
YBR077C |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MRN1 |
YPL184C |
RNA-binding protein that may be involved in translational regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FRT1 |
YOR324C |
Tail-anchored ER membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AMD2 |
YDR242W |
Putative amidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PXP1 |
YEL020C |
Peroxisomal matrix protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPE1 |
YJL121C |
D-ribulose-5-phosphate 3-epimerase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MLO127 |
YJR039W |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ISC1 |
YER019W |
Inositol phosphosphingolipid phospholipase C |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HAL9 |
YOL089C |
Putative transcription factor containing a zinc finger |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CUR1 |
YPR158W |
Sorting factor, central regulator of spatial protein quality control |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DAT1 |
YML113W |
DNA binding protein that recognizes oligo(dA).oligo(dT) tracts |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AGA1 |
YNR044W |
Anchorage subunit of a-agglutinin of a-cells |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
FRE5 |
YOR384W |
Putative ferric reductase with similarity to Fre2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FIT3 |
YOR383C |
Mannoprotein that is incorporated into the cell wall |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EMI1 |
YDR512C |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AFT2 |
YPL202C |
Iron-regulated transcriptional activator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATO2 |
YNR002C |
Putative transmembrane protein involved in export of ammonia |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ELO1 |
YJL196C |
Elongase I, medium-chain acyl elongase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CSM4 |
YPL200W |
Protein required for accurate chromosome segregation during meiosis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
COX12 |
YLR038C |
Subunit VIb of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CRT10 |
YOL063C |
Protein required for the degradation of mutant 25S rRNAs |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SLY41 |
YOR307C |
Protein involved in ER-to-Golgi transport |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
OPT1 |
YJL212C |
Proton-coupled oligopeptide transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STP2 |
YHR006W |
Transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PHA2 |
YNL316C |
Prephenate dehydratase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SCW10 |
YMR305C |
Cell wall protein with similarity to glucanases |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SET6 |
YPL165C |
SET domain protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MTO1 |
YGL236C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPS25A |
YGR027C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GPM3 |
YOL056W |
Nonfunctional homolog of Gpm1p phosphoglycerate mutase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ATH1 |
YPR026W |
Acid trehalase required for utilization of extracellular trehalose |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HIS1 |
YER055C |
ATP phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MAM3 |
YOL060C |
Protein involved in magnesium homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ARN1 |
YHL040C |
ARN family transporter for siderophore-iron chelates |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SRL1 |
YOR247W |
Mannoprotein that exhibits a tight association with the cell wall |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TDA5 |
YLR426W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MPC1 |
YGL080W |
Highly conserved subunit of mitochondrial pyruvate carrier (MPC) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
COX5B |
YIL111W |
Subunit Vb of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DPC25 |
YPL107W |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FSH3 |
YOR280C |
Putative serine hydrolase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MCP1 |
YOR228C |
Mitochondrial protein of unknown function involved in lipid homeostas |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MIC27 |
YNL100W |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ARR1 |
YPR199C |
Transcriptional activator of the basic leucine zipper (bZIP) family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HPF1 |
YOL155C |
Haze-protective mannoprotein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MZM1 |
YDR493W |
Protein required for assembly of the cytochrome bc(1) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MPC2 |
YHR162W |
Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
DSC2 |
YOL073C |
Multi-transmembrane subunit of the DSC ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LMO1 |
YLL007C |
Homolog of mammalian ELMO (Engulfment and celL MOtility) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CYT2 |
YKL087C |
Cytochrome c1 heme lyase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AGC1 |
YPR021C |
Mitochondrial amino acid transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AIM20 |
YIL158W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EFM4 |
YIL064W |
Lysine methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CPR8 |
YNR028W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GSH2 |
YOL049W |
Glutathione synthetase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LDS2 |
YOL047C |
Protein Involved in spore wall assembly |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
BIO5 |
YNR056C |
Putative transmembrane protein involved in the biotin biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MOD5 |
YOR274W |
Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LDO16 |
YMR148W |
Protein of unknown function with possible role in spore wall assembly |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ALE1 |
YOR175C |
Broad-specificity lysophospholipid acyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LEE1 |
YPL054W |
Zinc-finger protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FMP30 |
YPL103C |
Protein with a role in maintaining mitochondrial morphology |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MIX14 |
YDR031W |
Mitochondrial intermembrane space protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL24B |
YGR148C |
Ribosomal 60S subunit protein L24B |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
REH1 |
YLR387C |
Cytoplasmic 60S subunit biogenesis factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ENB1 |
YOL158C |
Ferric enterobactin transmembrane transporter |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATR2 |
YMR279C |
Putative boron transporter involved in boron efflux and resistance |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GUP2 |
YPL189W |
Probable membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MNN1 |
YER001W |
Alpha-1,3-mannosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FLX1 |
YIL134W |
Mitochondrial flavin adenine dinucleotide transporter |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AQY1 |
YPR192W |
Spore-specific water channel |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PET8 |
YNL003C |
S-adenosylmethionine transporter of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SMF2 |
YHR050W |
Divalent metal ion transporter involved in manganese homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HXT8 |
YJL214W |
Protein of unknown function with similarity to hexose transporters |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CNE1 |
YAL058W |
Calnexin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ODC1 |
YPL134C |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HXT17 |
YNR072W |
Putative transmembrane polyol transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ALG8 |
YOR067C |
Glucosyl transferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MFM1 |
YPL060W |
Mitochondrial inner membrane magnesium transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PXP2 |
YJR111C |
Peroxisomal matrix protein with naturally active promoter |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PEX35 |
YGR168C |
Regulator of peroxisome abundance |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS30B |
YOR182C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ARR2 |
YPR200C |
Arsenate reductase required for arsenate resistance |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MGR2 |
YPL098C |
Subunit of the TIM23 translocase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NGL1 |
YOL042W |
Putative endonuclease |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
OAR1 |
YKL055C |
Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MFA1 |
YDR461W |
Mating pheromone a-factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SCS3 |
YGL126W |
Protein required for normal ER membrane biosynthesis in response to ER |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PUS6 |
YGR169C |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS28B |
YLR264W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS29A |
YLR388W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SDH5 |
YOL071W |
Protein required for flavinylation of Sdh1p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CSS3 |
YOL159C |
Protein of unknown function, secreted when constitutively expressed |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS28A |
YOR167C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SCP1 |
YOR367W |
Component of yeast cortical actin cytoskeleton |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SFM1 |
YOR021C |
SPOUT methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HTC1 |
YPL067C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PAN6 |
YIL145C |
Pantothenate synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AIF1 |
YNR074C |
Mitochondrial cell death effector |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SPR3 |
YGR059W |
Sporulation-specific homolog of the CDC3/10/11/12 family of genes |
physical |
1 |
1 |
1 |
Two-hybrid |
SYM1 |
YLR251W |
Protein required for ethanol metabolism |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RKR1 |
YMR247C |
RING domain E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MSC6 |
YOR354C |
Multicopy suppressor of HER2 involved in mitochondrial translation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PGC1 |
YPL206C |
Phosphatidylglycerol phospholipase C |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SIM1 |
YIL123W |
Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PPM1 |
YDR435C |
Carboxyl methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SOL3 |
YHR163W |
6-phosphogluconolactonase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HPM1 |
YIL110W |
AdoMet-dependent methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SPE4 |
YLR146C |
Spermine synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MRX11 |
YPL041C |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
OXR1 |
YPL196W |
Protein involved in regulation of vacuolar V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRY3 |
YJL078C |
GPI-anchored cell wall protein involved in export of sterols |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SLH1 |
YGR271W |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MRX4 |
YPL168W |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TMA16 |
YOR252W |
Protein of unknown function that associates with ribosomes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FRE7 |
YOL152W |
Putative ferric reductase with similarity to Fre2p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FLO10 |
YKR102W |
Member of the FLO family of cell wall flocculation proteins |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
THI20 |
YOL055C |
Trifunctional enzyme of thiamine biosynthesis, degradation and salvage |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GRE1 |
YPL223C |
Hydrophilin essential in desiccation-rehydration process |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPO22 |
YIL073C |
Meiosis-specific protein essential for chromosome synapsis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TOM6 |
YOR045W |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MNE1 |
YOR350C |
Protein involved in splicing Group I aI5-beta intron from COX1 mRNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PAU23 |
YLR037C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HES1 |
YOR237W |
Protein implicated in the regulation of ergosterol biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MTC6 |
YHR151C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TRM10 |
YOL093W |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ECM23 |
YPL021W |
Non-essential protein of unconfirmed function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RTC5 |
YOR118W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SRL4 |
YPL033C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
FYV12 |
YOR183W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PAU4 |
YLR461W |
Member of the seripauperin multigene family |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RRT8 |
YOL048C |
Protein involved in spore wall assembly |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TPP1 |
YMR156C |
DNA 3'-phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RCH1 |
YMR034C |
Negative regulator of cytosolic calcium homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SPR2 |
YOR214C |
Putative spore wall protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TRP4 |
YDR354W |
Anthranilate phosphoribosyl transferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TDA6 |
YPR157W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHH3 |
YMR118C |
Putative mitochondrial inner membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SSU1 |
YPL092W |
Plasma membrane sulfite pump involved in sulfite metabolism |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TFB6 |
YOR352W |
Subunit of TFIIH complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MTC7 |
YEL033W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |