Standard name Systematic name Name description Description
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance Protein involved in mitochondrial fission and peroxisome abundance; may have a distinct role in tethering protein aggregates to mitochondria in order to retain them in the mother cell; required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation
Visualize the interactome of FIS1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.919 0.925 0.892
Vac/Vac Memb 0.054 NaN NaN
Mito NaN NaN 0.054

GFP localization & abundance

GFP localization GFP abundance
ambiguous 2410

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
FIS1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MDV1 YJL112W Peripheral protein of cytosolic face of mitochondrial outer membrane physical 22 6 11 Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Two-hybrid, Co-localization, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Two-hybrid, Affinity Capture-Western, Co-localization, Two-hybrid, Co-crystal Structure, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS
CAF4 YKR036C WD40 repeat-containing protein associated with the CCR4-NOT complex physical 11 5 5 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Two-hybrid, Co-localization, Co-crystal Structure, Two-hybrid, Affinity Capture-Western, Co-localization, Affinity Capture-Western, Affinity Capture-MS
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ATP20 YPR020W Subunit g of the mitochondrial F1F0 ATP synthase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance physical 4 3 3 Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
MDV1 YJL112W Peripheral protein of cytosolic face of mitochondrial outer membrane genetic 4 2 3 Dosage Rescue, Dosage Rescue, Phenotypic Enhancement, Phenotypic Enhancement
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUM1 YDR150W Protein required for nuclear migration genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MGR3 YMR115W Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
JNM1 YMR294W Component of the yeast dynactin complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization physical 3 2 3 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
NIP100 YPL174C Large subunit of the dynactin complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 3 2 2 Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Enhancement
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion genetic 3 2 2 Synthetic Rescue, Phenotypic Enhancement, Synthetic Rescue
CAF4 YKR036C WD40 repeat-containing protein associated with the CCR4-NOT complex genetic 3 1 2 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ATG11 YPR049C Adapter protein for pexophagy and the Cvt targeting pathway physical 2 2 2 FRET, PCA
HSP82 YPL240C Hsp90 chaperone genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 2 2 2 Negative Genetic, Positive Genetic
EMP24 YGL200C Component of the p24 complex genetic 2 1 2 Negative Genetic, Negative Genetic
DUR12 YBR208C Urea amidolyase genetic 2 1 2 Negative Genetic, Negative Genetic
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone genetic 2 1 2 Negative Genetic, Negative Genetic
ATP5 YDR298C Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase genetic 2 1 2 Negative Genetic, Negative Genetic
PEX34 YCL056C Protein that regulates peroxisome populations physical 2 1 2 Two-hybrid, Two-hybrid
MIC60 YKR016W Component of the MICOS complex genetic 2 1 2 Negative Genetic, Negative Genetic
SSD1 YDR293C Translational repressor genetic 2 1 2 Negative Genetic, Negative Genetic
TIM11 YDR322C-A Subunit e of mitochondrial F1F0-ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
YPT31 YER031C Rab family GTPase genetic 2 1 2 Negative Genetic, Negative Genetic
RTS3 YGR161C Putative component of the protein phosphatase type 2A complex genetic 2 1 2 Negative Genetic, Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 2 1 2 Negative Genetic, Negative Genetic
NFU1 YKL040C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 2 1 2 Positive Genetic, Positive Genetic
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation genetic 2 1 2 Negative Genetic, Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 2 1 2 Negative Genetic, Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 2 1 2 Negative Genetic, Negative Genetic
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 2 1 2 Negative Genetic, Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
LCB4 YOR171C Sphingoid long-chain base kinase genetic 2 1 2 Negative Genetic, Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 2 1 2 Negative Genetic, Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 2 1 2 Negative Genetic, Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 2 1 2 Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 1 2 Negative Genetic, Negative Genetic
CST9 YLR394W SUMO E3 ligase genetic 2 1 2 Negative Genetic, Negative Genetic
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 2 1 2 Negative Genetic, Negative Genetic
CPR8 YNR028W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 2 1 2 Negative Genetic, Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 2 2 1 Phenotypic Enhancement, Phenotypic Suppression
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LEU3 YLR451W Zinc-knuckle transcription factor, repressor and activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Positive Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Positive Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
BNI1 YNL271C Formin genetic 1 1 1 Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Positive Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
CUS1 YMR240C Protein required for assembly of U2 snRNP into the spliceosome genetic 1 1 1 Negative Genetic
CIA2 YHR122W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase physical 1 1 1 Affinity Capture-MS
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase physical 1 1 1 Affinity Capture-MS
CPA2 YJR109C Large subunit of carbamoyl phosphate synthetase physical 1 1 1 Affinity Capture-MS
ADE57 YGL234W Bifunctional enzyme of 'de novo' purine nucleotide pathway physical 1 1 1 Affinity Capture-MS
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization genetic 1 1 1 Negative Genetic
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Negative Genetic
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
DPS1 YLL018C Aspartyl-tRNA synthetase, primarily cytoplasmic physical 1 1 1 Affinity Capture-MS
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Reconstituted Complex
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
DLD3 YEL071W 2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase physical 1 1 1 Affinity Capture-MS
ACS2 YLR153C Acetyl-coA synthetase isoform physical 1 1 1 Affinity Capture-MS
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 1 1 1 Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase physical 1 1 1 PCA
ATG4 YNL223W Conserved cysteine protease required for autophagy genetic 1 1 1 Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
ARO9 YHR137W Aromatic aminotransferase II physical 1 1 1 Affinity Capture-MS
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Negative Genetic
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
BIT2 YBR270C Subunit of TORC2 membrane-associated complex genetic 1 1 1 Negative Genetic
BMT2 YBR141C Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
JSN1 YJR091C Member of the Puf family of RNA-binding proteins physical 1 1 1 Two-hybrid
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p physical 1 1 1 Two-hybrid
TPD3 YAL016W Regulatory subunit A of the heterotrimeric PP2A complex physical 1 1 1 Two-hybrid
SEC72 YLR292C Non-essential subunit of Sec63 complex physical 1 1 1 PCA
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone physical 1 1 1 Affinity Capture-Western
PLN1 YKR046C Perilipin, involved in formation and stability of lipid droplets physical 1 1 1 PCA
TUB2 YFL037W Beta-tubulin physical 1 1 1 Affinity Capture-Western
MIC60 YKR016W Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
PEX11 YOL147C Peroxisomal protein required for medium-chain fatty acid oxidation physical 1 1 1 Affinity Capture-Western
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) physical 1 1 1 Affinity Capture-MS
HSP60 YLR259C Tetradecameric mitochondrial chaperonin physical 1 1 1 Affinity Capture-MS
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Affinity Capture-MS
NOT5 YPR072W Component of the CCR4-NOT core complex, involved in mRNA decapping physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-MS
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
MET6 YER091C Cobalamin-independent methionine synthase physical 1 1 1 Affinity Capture-MS
SSA3 YBL075C ATPase involved in protein folding and the response to stress physical 1 1 1 Affinity Capture-MS
YHR214C-B YHR214C-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
TKL1 YPR074C Transketolase physical 1 1 1 Affinity Capture-MS
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
TIF2 YJL138C Translation initiation factor eIF4A physical 1 1 1 Affinity Capture-MS
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 1 1 1 Affinity Capture-MS
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
MRX18 YBR056W Putative glycoside hydrolase of the mitochondrial intermembrane space physical 1 1 1 Affinity Capture-MS
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) physical 1 1 1 Affinity Capture-MS
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 Affinity Capture-MS
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase physical 1 1 1 Affinity Capture-MS
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) physical 1 1 1 Affinity Capture-MS
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p physical 1 1 1 Affinity Capture-MS
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 Affinity Capture-MS
LYS21 YDL131W Homocitrate synthase isozyme physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein physical 1 1 1 Affinity Capture-MS
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs physical 1 1 1 Affinity Capture-MS
TDH2 YJR009C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 physical 1 1 1 Affinity Capture-MS
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 Affinity Capture-MS
HMRA1 YCR097W Silenced copy of a1 at HMR physical 1 1 1 Affinity Capture-MS
RPL17A YKL180W Ribosomal 60S subunit protein L17A physical 1 1 1 Affinity Capture-MS
RPL22A YLR061W Ribosomal 60S subunit protein L22A physical 1 1 1 Affinity Capture-MS
MET17 YLR303W O-acetyl homoserine-O-acetyl serine sulfhydrylase physical 1 1 1 Affinity Capture-MS
SAM2 YDR502C S-adenosylmethionine synthetase physical 1 1 1 Affinity Capture-MS
PGI1 YBR196C Glycolytic enzyme phosphoglucose isomerase physical 1 1 1 Affinity Capture-MS
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 1 1 1 Affinity Capture-MS
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone physical 1 1 1 Affinity Capture-MS
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Affinity Capture-MS
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
KGD2 YDR148C Dihydrolipoyl transsuccinylase physical 1 1 1 Affinity Capture-MS
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) physical 1 1 1 Affinity Capture-MS
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter physical 1 1 1 Affinity Capture-MS
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 1 1 1 Affinity Capture-MS
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Negative Genetic
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
MAE1 YKL029C Mitochondrial malic enzyme physical 1 1 1 Affinity Capture-MS
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
SSP120 YLR250W Protein packaged into COPII vesicles for ER to Golgi trafficking physical 1 1 1 Affinity Capture-MS
TDA10 YGR205W ATP-binding protein of unknown function physical 1 1 1 Affinity Capture-MS
VPS70 YJR126C Protein of unknown function involved in vacuolar protein sorting physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL1B YGL135W Ribosomal 60S subunit protein L1B physical 1 1 1 Affinity Capture-MS
PRP43 YGL120C RNA helicase in the DEAH-box family physical 1 1 1 Affinity Capture-MS
UBI4 YLL039C Ubiquitin physical 1 1 1 Affinity Capture-MS
YPR1 YDR368W NADPH-dependent aldo-keto reductase physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs physical 1 1 1 Reconstituted Complex
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
MGM1 YOR211C Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p genetic 1 1 1 Synthetic Rescue
POP4 YBR257W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
SHR3 YDL212W Endoplasmic reticulum packaging chaperone genetic 1 1 1 Negative Genetic
SRF1 YDL133W Regulator of phospholipase D (Spo14p) genetic 1 1 1 Positive Genetic
PAU10 YDR542W Protein of unknown function genetic 1 1 1 Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
RPL26B YGR034W Ribosomal 60S subunit protein L26B genetic 1 1 1 Negative Genetic
SPR3 YGR059W Sporulation-specific homolog of the CDC3/10/11/12 family of genes genetic 1 1 1 Negative Genetic
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
YGR266W YGR266W Protein of unknown function genetic 1 1 1 Negative Genetic
RTC3 YHR087W Protein of unknown function involved in RNA metabolism genetic 1 1 1 Negative Genetic
OSM1 YJR051W Fumarate reductase, catalyzes the reduction of fumarate to succinate genetic 1 1 1 Negative Genetic
URA8 YJR103W Minor CTP synthase isozyme (see also URA7) genetic 1 1 1 Negative Genetic
YJR120W YJR120W Protein of unknown function genetic 1 1 1 Negative Genetic
JEN1 YKL217W Monocarboxylate/proton symporter of the plasma membrane genetic 1 1 1 Negative Genetic
YKR018C YKR018C Protein of unknown function genetic 1 1 1 Negative Genetic
YLL058W YLL058W Putative protein of unknown function with similarity to Str2p genetic 1 1 1 Negative Genetic
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
HXT2 YMR011W High-affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Positive Genetic
HOL1 YNR055C Putative transporter in the major facilitator superfamily genetic 1 1 1 Negative Genetic
FRE7 YOL152W Putative ferric reductase with similarity to Fre2p genetic 1 1 1 Negative Genetic
MCP1 YOR228C Mitochondrial protein of unknown function involved in lipid homeostas genetic 1 1 1 Negative Genetic
OYE3 YPL171C Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Positive Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 1 1 1 Positive Genetic
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Negative Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Negative Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
MHR1 YDR296W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Phenotypic Enhancement
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Positive Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Positive Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Positive Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Positive Genetic
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 1 1 1 Positive Genetic
PRM7 YDL039C Pheromone-regulated protein genetic 1 1 1 Positive Genetic
UBP1 YDL122W Ubiquitin-specific protease genetic 1 1 1 Positive Genetic
YGL114W YGL114W Putative protein of unknown function genetic 1 1 1 Positive Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Positive Genetic
PCP1 YGR101W Mitochondrial serine protease genetic 1 1 1 Positive Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Positive Genetic
MRPL6 YHR147C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Positive Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Positive Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Positive Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Positive Genetic
SMY1 YKL079W Kinesin-like myosin passenger-protein genetic 1 1 1 Positive Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
YNR021W YNR021W Putative protein of unknown function genetic 1 1 1 Positive Genetic
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Positive Genetic
ISU1 YPL135W Conserved protein of the mitochondrial matrix genetic 1 1 1 Positive Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Negative Genetic
GCD2 YGR083C Delta subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
GRC3 YLL035W Polynucleotide kinase present on rDNA genetic 1 1 1 Negative Genetic
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 1 1 1 Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Negative Genetic
SMD1 YGR074W Core Sm protein Sm D1 genetic 1 1 1 Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Negative Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Negative Genetic
SLX1 YBR228W Endonuclease involved in DNA recombination and repair genetic 1 1 1 Negative Genetic
RGT2 YDL138W Plasma membrane high glucose sensor that regulates glucose transport genetic 1 1 1 Negative Genetic
LRG1 YDL240W GTPase-activating protein (GAP) genetic 1 1 1 Negative Genetic
NSI1 YDR026C RNA polymerase I termination factor genetic 1 1 1 Negative Genetic
NVJ3 YDR179W-A Protein with a potential role in tethering ER and vacuoles genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
YDR391C YDR391C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YPS5 YGL259W Protein with similarity to GPI-anchored aspartic proteases genetic 1 1 1 Negative Genetic
YGR035C YGR035C Putative protein of unknown function, potential Cdc28p substrate genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
XKS1 YGR194C Xylulokinase genetic 1 1 1 Negative Genetic
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
RPL35A YDL191W Ribosomal 60S subunit protein L35A genetic 1 1 1 Negative Genetic
GEP7 YGL057C Protein of unknown function genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
MGR2 YPL098C Subunit of the TIM23 translocase complex genetic 1 1 1 Negative Genetic
RTC6 YPL183W-A Protein involved in translation genetic 1 1 1 Negative Genetic
YJL163C YJL163C Putative protein of unknown function genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
YKL075C YKL075C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL6B YLR448W Ribosomal 60S subunit protein L6B genetic 1 1 1 Negative Genetic
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder genetic 1 1 1 Negative Genetic
ICY1 YMR195W Protein of unknown function genetic 1 1 1 Negative Genetic
MIC27 YNL100W Component of the MICOS complex genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
GSH2 YOL049W Glutathione synthetase genetic 1 1 1 Negative Genetic
TIR4 YOR009W Cell wall mannoprotein genetic 1 1 1 Negative Genetic
RPL20B YOR312C Ribosomal 60S subunit protein L20B genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Positive Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Positive Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 1 1 1 Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Synthetic Rescue
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Positive Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Negative Genetic
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Negative Genetic
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
CLC1 YGR167W Clathrin light chain genetic 1 1 1 Positive Genetic
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
ENT5 YDR153C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Negative Genetic
ASN2 YGR124W Asparagine synthetase physical 1 1 1 Affinity Capture-MS
ANT1 YPR128C Peroxisomal adenine nucleotide transporter genetic 1 1 1 Positive Genetic
COQ10 YOL008W Coenzyme Q (ubiquinone) binding protein genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
ALD6 YPL061W Cytosolic aldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Positive Genetic
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Positive Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Positive Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Positive Genetic
ARO7 YPR060C Chorismate mutase genetic 1 1 1 Positive Genetic
BOL1 YAL044W-A Mitochondrial matrix protein involved in Fe-S cluster biogenesis physical 1 1 1 Affinity Capture-MS
ALK1 YGL021W Atypical protein kinase genetic 1 1 1 Negative Genetic
COX20 YDR231C Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3 genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic