ERP1 |
YAR002C-A |
Member of the p24 family involved in ER to Golgi transport |
physical |
9 |
3 |
6 |
Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
ERP2 |
YAL007C |
Member of the p24 family involved in ER to Golgi transport |
physical |
6 |
3 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS, Affinity Capture-Western |
ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
physical |
6 |
3 |
5 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PMT1 |
YDL095W |
Protein O-mannosyltransferase of the ER membrane |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC13 |
YLR208W |
Structural component of 3 complexes |
genetic |
3 |
1 |
3 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SAR1 |
YPL218W |
ARF family GTPase |
physical |
3 |
3 |
2 |
Affinity Capture-Western, Reconstituted Complex, Co-purification |
ERP4 |
YOR016C |
Member of the p24 family involved in ER to Golgi transport |
physical |
3 |
3 |
2 |
PCA, Affinity Capture-MS, Affinity Capture-Western |
ERP5 |
YHR110W |
Protein with similarity to Emp24p and Erv25p |
physical |
3 |
3 |
2 |
PCA, Affinity Capture-MS, Affinity Capture-Western |
ERP3 |
YDL018C |
Protein with similarity to Emp24p and Erv25p |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect |
BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression |
ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
2 |
2 |
Synthetic Haploinsufficiency, Positive Genetic |
SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Co-purification |
SEC13 |
YLR208W |
Structural component of 3 complexes |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
SEC21 |
YNL287W |
Gamma subunit of coatomer |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Lethality |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
GEM1 |
YAL048C |
Outer mitochondrial membrane GTPase, subunit of the ERMES complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YHR045W |
YHR045W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS4B |
YHR203C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SOP4 |
YJL192C |
ER-membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RSF2 |
YJR127C |
Zinc-finger protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HFL1 |
YKR051W |
Vacuole membrane protein that interacts with Atg8p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YNL095C |
YNL095C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MDM12 |
YOL009C |
Mitochondrial outer membrane protein, ERMES complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MCP1 |
YOR228C |
Mitochondrial protein of unknown function involved in lipid homeostas |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CHS1 |
YNL192W |
Chitin synthase I |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CHS3 |
YBR023C |
Chitin synthase III |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
DDR48 |
YMR173W |
DNA damage-responsive protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-MS |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Synthetic Rescue |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YIP5 |
YGL161C |
Protein that interacts with Rab GTPases |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
CCC2 |
YDR270W |
Cu(+2)-transporting P-type ATPase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
LEU3 |
YLR451W |
Zinc-knuckle transcription factor, repressor and activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP7 |
YPR034W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Reconstituted Complex |
NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBP4 |
YDL053C |
Pbp1p binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GSY1 |
YFR015C |
Glycogen synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NMD5 |
YJR132W |
Karyopherin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TAT1 |
YBR069C |
Amino acid transporter for valine, leucine, isoleucine, and tyrosine |
physical |
1 |
1 |
1 |
PCA |
SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
physical |
1 |
1 |
1 |
PCA |
IFA38 |
YBR159W |
Microsomal beta-keto-reductase |
physical |
1 |
1 |
1 |
PCA |
TSC13 |
YDL015C |
Enoyl reductase |
physical |
1 |
1 |
1 |
PCA |
UGA4 |
YDL210W |
GABA (gamma-aminobutyrate) permease |
physical |
1 |
1 |
1 |
PCA |
SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
physical |
1 |
1 |
1 |
PCA |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
physical |
1 |
1 |
1 |
PCA |
TMN2 |
YDR107C |
Protein with a role in cellular adhesion and filamentous growth |
physical |
1 |
1 |
1 |
PCA |
SUR2 |
YDR297W |
Sphinganine C4-hydroxylase |
physical |
1 |
1 |
1 |
PCA |
PMP2 |
YEL017C-A |
Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p) |
physical |
1 |
1 |
1 |
PCA |
MST27 |
YGL051W |
Putative integral membrane protein, involved in vesicle formation |
physical |
1 |
1 |
1 |
PCA |
ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
physical |
1 |
1 |
1 |
PCA |
ERV29 |
YGR284C |
Protein localized to COPII-coated vesicles |
physical |
1 |
1 |
1 |
PCA |
EPT1 |
YHR123W |
sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase |
physical |
1 |
1 |
1 |
PCA |
YHR140W |
YHR140W |
Endoplasmic reticulum protein |
physical |
1 |
1 |
1 |
PCA |
SNL1 |
YIL016W |
Ribosome-associated protein |
physical |
1 |
1 |
1 |
PCA |
PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
physical |
1 |
1 |
1 |
PCA |
STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
physical |
1 |
1 |
1 |
PCA |
YET1 |
YKL065C |
Endoplasmic reticulum transmembrane protein |
physical |
1 |
1 |
1 |
PCA |
SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
physical |
1 |
1 |
1 |
PCA |
SEC61 |
YLR378C |
Conserved ER protein translocation channel |
physical |
1 |
1 |
1 |
PCA |
GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
physical |
1 |
1 |
1 |
PCA |
GAS3 |
YMR215W |
Putative 1,3-beta-glucanosyltransferase |
physical |
1 |
1 |
1 |
PCA |
TPO2 |
YGR138C |
Polyamine transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
PCA |
PRM10 |
YJL108C |
Pheromone-regulated protein |
physical |
1 |
1 |
1 |
PCA |
OPT2 |
YPR194C |
Oligopeptide transporter |
physical |
1 |
1 |
1 |
PCA |
EMP24 |
YGL200C |
Component of the p24 complex |
physical |
1 |
1 |
1 |
PCA |
PMT1 |
YDL095W |
Protein O-mannosyltransferase of the ER membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPS1 |
YLR120C |
Aspartic protease |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
physical |
1 |
1 |
1 |
Protein-peptide |
PRP40 |
YKL012W |
U1 snRNP protein involved in splicing |
physical |
1 |
1 |
1 |
Protein-peptide |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERP6 |
YGL002W |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRT6 |
YGL146C |
Integral membrane protein, member of the p24 family |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS34 |
YLR240W |
Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS15 |
YBR097W |
Serine/threonine protein kinase involved in vacuolar protein sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCS3 |
YGL126W |
Protein required for normal ER membrane biosynthesis in response to ER |
physical |
1 |
1 |
1 |
PCA |
GEA1 |
YJR031C |
Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
GEA1 |
YJR031C |
Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC21 |
YNL287W |
Gamma subunit of coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
HKR1 |
YDR420W |
Mucin family member that functions as an osmosensor in the HOG pathway |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PAN3 |
YKL025C |
Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
INP51 |
YIL002C |
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Positive Genetic |
RSO55 |
YLR281C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
FRE7 |
YOL152W |
Putative ferric reductase with similarity to Fre2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTC5 |
YOR118W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KRE6 |
YPR159W |
Glucosyl hydrolase required for beta-1,6-glucan biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SVP26 |
YHR181W |
ER exit adaptor for Golgi mannosyltransferases |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MNL2 |
YLR057W |
Putative mannosidase involved in ER-associated protein degradation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMT4 |
YJR143C |
Protein O-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT1 |
YFL038C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RER1 |
YCL001W |
Protein involved in retention of membrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK16 |
YAL025C |
Essential nuclear protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPC19 |
YDR201W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI1 |
YGR216C |
Membrane protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
MOB1 |
YIL106W |
Component of the mitotic exit network |
genetic |
1 |
1 |
1 |
Positive Genetic |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MVD1 |
YNR043W |
Mevalonate pyrophosphate decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Positive Genetic |
NSL1 |
YPL233W |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERD2 |
YBL040C |
HDEL receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEL2 |
YGR099W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKI6 |
YGR195W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRE9 |
YJL174W |
Glycoprotein involved in cell wall beta-glucan assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
GFA1 |
YKL104C |
Glutamine-fructose-6-phosphate amidotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLN4 |
YOR168W |
Glutamine tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NVJ3 |
YDR179W-A |
Protein with a potential role in tethering ER and vacuoles |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRD3 |
YLR207W |
ER membrane protein that plays a central role in ERAD |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
GEA2 |
YEL022W |
Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG27 |
YJL178C |
Type I membrane protein involved in autophagy and the Cvt pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CPT1 |
YNL130C |
Cholinephosphotransferase |
physical |
1 |
1 |
1 |
PCA |
ATG23 |
YLR431C |
Peripheral membrane protein required for autophagy and CVT |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG8 |
YBL078C |
Ub-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BRN1 |
YBL097W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
physical |
1 |
1 |
1 |
PCA |
ELO3 |
YLR372W |
Elongase |
physical |
1 |
1 |
1 |
PCA |
ELO3 |
YLR372W |
Elongase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ALG5 |
YPL227C |
UDP-glucose:dolichyl-phosphate glucosyltransferase |
physical |
1 |
1 |
1 |
PCA |
AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARR3 |
YPR201W |
Plasma membrane metalloid/H+ antiporter |
physical |
1 |
1 |
1 |
PCA |
ALG1 |
YBR110W |
Mannosyltransferase |
physical |
1 |
1 |
1 |
PCA |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAB4 |
YGR277C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CWP2 |
YKL096W-A |
Covalently linked cell wall mannoprotein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
DNF1 |
YER166W |
Aminophospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
PCA |
CWH41 |
YGL027C |
Processing alpha glucosidase I |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CCW14 |
YLR390W-A |
Covalently linked cell wall glycoprotein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |