YCF1 |
YDR135C |
Vacuolar glutathione S-conjugate transporter |
genetic |
7 |
3 |
6 |
Synthetic Growth Defect, Phenotypic Enhancement, Dosage Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Dosage Rescue, Synthetic Growth Defect |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ARR1 |
YPR199C |
Transcriptional activator of the basic leucine zipper (bZIP) family |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENA2 |
YDR039C |
P-type ATPase sodium pump |
physical |
1 |
1 |
1 |
PCA |
EMP24 |
YGL200C |
Component of the p24 complex |
physical |
1 |
1 |
1 |
PCA |
ERP2 |
YAL007C |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
PCA |
SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
physical |
1 |
1 |
1 |
PCA |
IFA38 |
YBR159W |
Microsomal beta-keto-reductase |
physical |
1 |
1 |
1 |
PCA |
GMC1 |
YDR506C |
Protein involved in meiotic progression |
physical |
1 |
1 |
1 |
PCA |
VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
physical |
1 |
1 |
1 |
PCA |
CBP4 |
YGR174C |
Mitochondrial protein required for assembly of cytochrome bc1 complex |
physical |
1 |
1 |
1 |
PCA |
ERP4 |
YOR016C |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
PCA |
MRL1 |
YPR079W |
Membrane protein |
physical |
1 |
1 |
1 |
PCA |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MET4 |
YNL103W |
Leucine-zipper transcriptional activator |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ARR3 |
YPR201W |
Plasma membrane metalloid/H+ antiporter |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
OPT2 |
YPR194C |
Oligopeptide transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRY1 |
YKL218C |
3-hydroxyaspartate dehydratase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Positive Genetic |
NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEM12 |
YDR047W |
Uroporphyrinogen decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBS1 |
YDL069C |
Mitochondrial translational activator of the COB mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL2A |
YFR031C-A |
Ribosomal 60S subunit protein L2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL6 |
YHR147C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS55 |
YJR044C |
Late endosomal protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSM26 |
YJR101W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX19 |
YDL065C |
Chaperone and import receptor for newly-synthesized class I PMPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX5 |
YDR244W |
Peroxisomal membrane signal receptor for peroxisomal matrix proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX14 |
YGL153W |
Central component of the peroxisomal importomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX4 |
YGR133W |
Peroxisomal ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
genetic |
1 |
1 |
1 |
Negative Genetic |
GND2 |
YGR256W |
6-phosphogluconate dehydrogenase (decarboxylating) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
NVJ1 |
YHR195W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TDA4 |
YJR116W |
Protein distantly similar to ceramide synthases, Lag1p and Lac1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENT3 |
YJR125C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAN1 |
YJR150C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX1 |
YKL197C |
AAA-peroxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX13 |
YLR191W |
Peroxisomal importomer complex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT7 |
YML001W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS18B |
YML026C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARR2 |
YPR200C |
Arsenate reductase required for arsenate resistance |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |